mirDNMR
mirDNMR is a database for the collection of gene-centered background DNMRs obtained from different methods and population variation data. The database has the following functions: (i) browse and search the background DNMRs of each gene predicted by four different methods, including GC content (DNMR-GC), sequence context (DNMR-SC), multiple factors (DNMR-MF) and local DNA methylation level (DNMR-DM); (ii) search variant frequencies in publicly available databases, including ExAC, ESP6500, UK10K, 1000G and dbSNP and (iii) investigate the DNM burden to prioritize candidate genes based on the four background DNMRs using three statistical methods (TADA, Binomial and Poisson test). In conclusion, mirDNMR can be widely used to identify the genetic basis of sporadic genetic diseases.
Description
More detailed information about this field from each metasource.
mirDNMR is a database for the collection of gene-centered background DNMRs obtained from different methods and population variation data. The database has the following functions: (i) browse and search the background DNMRs of each gene predicted by four different methods, including GC content (DNMR-GC), sequence context (DNMR-SC), multiple factors (DNMR-MF) and local DNA methylation level (DNMR-DM); (ii) search variant frequencies in publicly available databases, including ExAC, ESP6500, UK10K, 1000G and dbSNP and (iii) investigate the DNM burden to prioritize candidate genes based on the four background DNMRs using three statistical methods (TADA, Binomial and Poisson test). In conclusion, mirDNMR can be widely used to identify the genetic basis of sporadic genetic diseases.
metasource: Fairsharing.orgversion: FAIRsharing.org: mirDNMR; mirDNMR; DOI: https://doi.org/10.25504/FAIRsharing.68f4xz; Last edited: Jan. 8, 2019, 1:23 p.m.; Last accessed: Jan 03 2022 7:05 p.m.
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657
Webpage:
https://www.wzgenomics.cn/mirdnmr/Webpage
More detailed information about this field from each metasource.
https://www.wzgenomics.cn/mirdnmr/
metasource: Fairsharing.orgversion: FAIRsharing.org: mirDNMR; mirDNMR; DOI: https://doi.org/10.25504/FAIRsharing.68f4xz; Last edited: Jan. 8, 2019, 1:23 p.m.; Last accessed: Jan 03 2022 7:05 p.m.
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657
Publications:
Publications
More detailed information about this field from each metasource.
mirDNMR: a gene-centered database of background de novo mutation rates in human
PMID: 27799474
metasource: Fairsharing.org
version: FAIRsharing.org: mirDNMR; mirDNMR; DOI: https://doi.org/10.25504/FAIRsharing.68f4xz; Last edited: Jan. 8, 2019, 1:23 p.m.; Last accessed: Jan 03 2022 7:05 p.m.
http://dx.doi.org/10.1093/nar/1964
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657
Publications
More detailed information about this field from each metasource.
mirDNMR: a gene-centered database of background de novo mutation rates in human
PMID: 27799474
metasource: Fairsharing.org
version: FAIRsharing.org: mirDNMR; mirDNMR; DOI: https://doi.org/10.25504/FAIRsharing.68f4xz; Last edited: Jan. 8, 2019, 1:23 p.m.; Last accessed: Jan 03 2022 7:05 p.m.
http://dx.doi.org/10.1093/nar/1964
metasource: Nucleic Acid Research database catalogueversion: extracted_at: 2022-11-04T11:16:25.468657
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mirDNMR: a gene-centered database of background de novo mutation rates in human
PubMed citations: 4.
4 articles citing: mirDNMR: a gene-centered database of background de novo mutation rates in human
Gene4Denovo: an integrated database and analytic platform for de novo mutations in humans. PMID:31642496
De novo Mutations From Whole Exome Sequencing in Neurodevelopmental and Psychiatric Disorders: From Discovery to Application. PMID:31001316
Prioritized High-Confidence Risk Genes for Intellectual Disability Reveal Molecular Convergence During Brain Development. PMID:30279698
The 24th annual Nucleic Acids Research database issue: a look back and upcoming changes. PMID:28053160 - http://dx.doi.org/10.1093/nar/1964
Tags:
Tags
More detailed information about this field from each metasource.
mutation
metasource: Fairsharing.org
version: FAIRsharing.org: mirDNMR; mirDNMR; DOI: https://doi.org/10.25504/FAIRsharing.68f4xz; Last edited: Jan. 8, 2019, 1:23 p.m.; Last accessed: Jan 03 2022 7:05 p.m.
mutation analysis
metasource: Fairsharing.org
version: FAIRsharing.org: mirDNMR; mirDNMR; DOI: https://doi.org/10.25504/FAIRsharing.68f4xz; Last edited: Jan. 8, 2019, 1:23 p.m.; Last accessed: Jan 03 2022 7:05 p.m.
human genes and diseases
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657
general polymorphism databases
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657
Tags
More detailed information about this field from each metasource.
mutation
metasource: Fairsharing.orgversion: FAIRsharing.org: mirDNMR; mirDNMR; DOI: https://doi.org/10.25504/FAIRsharing.68f4xz; Last edited: Jan. 8, 2019, 1:23 p.m.; Last accessed: Jan 03 2022 7:05 p.m.
mutation analysis
metasource: Fairsharing.orgversion: FAIRsharing.org: mirDNMR; mirDNMR; DOI: https://doi.org/10.25504/FAIRsharing.68f4xz; Last edited: Jan. 8, 2019, 1:23 p.m.; Last accessed: Jan 03 2022 7:05 p.m.
human genes and diseases
metasource: Nucleic Acid Research database catalogueversion: extracted_at: 2022-11-04T11:16:25.468657
general polymorphism databases
metasource: Nucleic Acid Research database catalogueversion: extracted_at: 2022-11-04T11:16:25.468657
mutation mutation analysis human genes and diseases polymorphism
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