Solution structure of the type I polyketide synthase Pks13 from Mycobacterium tuberculosis.
PMID:35729566
A MademoiseLLE domain binding platform links the key RNA transporter to endosomes.
PMID:35727840
Structural Characterization of the Full-Length Anti-CD20 Antibody Rituximab.
PMID:35480889
Integration of Experimental Data and Use of Automated Fitting Methods in Developing Protein Force Fields.
PMID:35382231
Overall structure of fully assembled cyanobacterial KaiABC circadian clock complex by an integrated experimental-computational approach.
PMID:35273347
Solution structure and dynamics of the mitochondrial-targeted GTPase-activating protein (GAP) VopE by an integrated NMR/SAXS approach.
PMID:35137487
Experimental Evidence of Intrinsic Disorder and Amyloid Formation by the Henipavirus W Proteins.
PMID:35055108
An integrative NMR-SAXS approach for structural determination of large RNAs defines the substrate-free state of a trans-cleaving Neurospora Varkud Satellite ribozyme.
PMID:34718697
Identification of a Region in the Common Amino-terminal Domain of Hendra Virus P, V, and W Proteins Responsible for Phase Transition and Amyloid Formation.
PMID:34572537
Mechanism of activation and regulation of deubiquitinase activity in MINDY1 and MINDY2.
PMID:34529927
pUL21 is a viral phosphatase adaptor that promotes herpes simplex virus replication and spread.
PMID:34398933
Decoding the intricate network of molecular interactions of a hyperstable engineered biocatalyst.
PMID:34094357
From integrative structural biology to cell biology.
PMID:33957123
Rational thermostabilisation of four-helix bundle dimeric de novo proteins.
PMID:33824364
Conjuring up a ghost: structural and functional characterization of FhuF, a ferric siderophore reductase from E. coli.
PMID:33559753
SHP2 Nuclear/Cytoplasmic Trafficking in Granulosa Cells Is Essential for Oocyte Meiotic Resumption and Maturation.
PMID:33553147
Interdomain Flexibility of Chikungunya Virus nsP2 Helicase-Protease Differentially Influences Viral RNA Replication and Infectivity.
PMID:33328310
Structures of three MORN repeat proteins and a re-evaluation of the proposed lipid-binding properties of MORN repeats.
PMID:33296386
Ensemble description of the intrinsically disordered N-terminal domain of the Nipah virus P/V protein from combined NMR and SAXS.
PMID:33177626
Structural basis for DNA recognition and allosteric control of the retinoic acid receptors RAR-RXR.
PMID:32974652
Structural analysis of a new carotenoid-binding protein: the C-terminal domain homolog of the OCP.
PMID:32968135
RovC - a novel type of hexameric transcriptional activator promoting type VI secretion gene expression.
PMID:32966346
Characterization of the nucleotide-binding domain NsrF from the BceAB-type ABC-transporter NsrFP from the human pathogen Streptococcus agalactiae.
PMID:32938989
Architecture and functional dynamics of the pentafunctional AROM complex.
PMID:32632294
Integrated Structural Modeling of Full-Length LRH-1 Reveals Inter-domain Interactions Contribute to Receptor Structure and Function.
PMID:32433991
An automated data processing and analysis pipeline for transmembrane proteins in detergent solutions.
PMID:32415234
Insights into herpesvirus assembly from the structure of the pUL7:pUL51 complex.
PMID:32391791
The HDOCK server for integrated protein-protein docking.
PMID:32269383
Determination of Protein Structural Ensembles by Hybrid-Resolution SAXS Restrained Molecular Dynamics.
PMID:32119546
Structural basis of cell-surface signaling by a conserved sigma regulator in Gram-negative bacteria.
PMID:32107313
Structure of the G protein chaperone and guanine nucleotide exchange factor Ric-8A bound to Gαi1.
PMID:32103024
Model Reconstruction from Small-Angle X-Ray Scattering Data Using Deep Learning Methods.
PMID:32092702
Obtaining Tertiary Protein Structures by the ab Initio Interpretation of Small Angle X-ray Scattering Data.
PMID:32023061
Zinc-finger protein CNBP alters the 3-D structure of lncRNA Braveheart in solution.
PMID:31919376
Conformational States of Exchange Protein Directly Activated by cAMP (EPAC1) Revealed by Ensemble Modeling and Integrative Structural Biology.
PMID:31877746
Staufen1 reads out structure and sequence features in ARF1 dsRNA for target recognition.
PMID:31875226
SAXSDom: Modeling multidomain protein structures using small-angle X-ray scattering data.
PMID:31860156
Structural Insights into the Intracellular Region of the Human Magnesium Transport Mediator CNNM4.
PMID:31842432
An intrinsically disordered proteins community for ELIXIR.
PMID:31824649
Federating Structural Models and Data: Outcomes from A Workshop on Archiving Integrative Structures.
PMID:31780431
Combination of SAXS and Protein Painting Discloses the Three-Dimensional Organization of the Bacterial Cysteine Synthase Complex, a Potential Target for Enhancers of Antibiotic Action.
PMID:31640223
Structural Organization and Dynamics of Homodimeric Cytohesin Family Arf GTPase Exchange Factors in Solution and on Membranes.
PMID:31601460
Structure of tRNA methyltransferase complex of Trm7 and Trm734 reveals a novel binding interface for tRNA recognition.
PMID:31586407
Aldehyde-alcohol dehydrogenase forms a high-order spirosome architecture critical for its activity.
PMID:31586059
Reporting on the future of integrative structural biology ORAU workshop.
PMID:31585877
SASBDB: Towards an automatically curated and validated repository for biological scattering data.
PMID:31576635
Structural and mechanistic insights into the interaction of the circadian transcription factor BMAL1 with the KIX domain of the CREB-binding protein.
PMID:31515273
Interaction of the tetratricopeptide repeat domain of aryl hydrocarbon receptor-interacting protein-like 1 with the regulatory Pγ subunit of phosphodiesterase 6.
PMID:31488544
Defects in t6A tRNA modification due to GON7 and YRDC mutations lead to Galloway-Mowat syndrome.
PMID:31481669
Solution structure and flexibility of the condensin HEAT-repeat subunit Ycg1.
PMID:31350339
Archiving and disseminating integrative structure models.
PMID:31278630
Solution Structure of SpoIVB Reveals Mechanism of PDZ Domain-Regulated Protease Activity.
PMID:31244791
Evolving SAXS versatility: solution X-ray scattering for macromolecular architecture, functional landscapes, and integrative structural biology.
PMID:31204190
Quaternary structure of α-amino-β-carboxymuconate-ϵ-semialdehyde decarboxylase (ACMSD) controls its activity.
PMID:31189654
Molecular Fingerprints for a Novel Enzyme Family in Actinobacteria with Glucosamine Kinase Activity.
PMID:31088917
Unique structural features of a bacterial autotransporter adhesin suggest mechanisms for interaction with host macromolecules.
PMID:31036849
Structure, dynamics and roX2-lncRNA binding of tandem double-stranded RNA binding domains dsRBD1,2 of Drosophila helicase Maleless.
PMID:30805612
Octa-repeat domain of the mammalian prion protein mRNA forms stable A-helical hairpin structure rather than G-quadruplexes.
PMID:30792490
Quantitative live-cell imaging and 3D modeling reveal critical functional features in the cytosolic complex of phagocyte NADPH oxidase.
PMID:30630949
A Metastable Contact and Structural Disorder in the Estrogen Receptor Transactivation Domain.
PMID:30581045
Structural and Biochemical Characterization of Aldehyde Dehydrogenase 12, the Last Enzyme of Proline Catabolism in Plants.
PMID:30580036
Crystal Structure of Aldehyde Dehydrogenase 16 Reveals Trans-Hierarchical Structural Similarity and a New Dimer.
PMID:30529746
CH2 domain orientation of human immunoglobulin G in solution: Structural comparison of glycosylated and aglycosylated Fc regions using small-angle X-ray scattering.
PMID:30513259
Mechanism of activating mutations and allosteric drug inhibition of the phosphatase SHP2.
PMID:30375376
SAXSMoW 2.0: Online calculator of the molecular weight of proteins in dilute solution from experimental SAXS data measured on a relative scale.
PMID:30371978
Protein Data Bank: the single global archive for 3D macromolecular structure data.
PMID:30357364
The molecular basis of protein toxin HicA-dependent binding of the protein antitoxin HicB to DNA.
PMID:30337369
The role of small-angle scattering in structure-based screening applications.
PMID:30306530
OCP-FRP protein complex topologies suggest a mechanism for controlling high light tolerance in cyanobacteria.
PMID:30250028
Human MICAL1: Activation by the small GTPase Rab8 and small-angle X-ray scattering studies on the oligomerization state of MICAL1 and its complex with Rab8.
PMID:30242933
Searching for 3D structural models from a library of biological shapes using a few 2D experimental images.
PMID:30208849
Human Dystrophin Structural Changes upon Binding to Anionic Membrane Lipids.
PMID:30197181
NAD+ promotes assembly of the active tetramer of aldehyde dehydrogenase 7A1.
PMID:30184263
Multidomain architecture of estrogen receptor reveals interfacial cross-talk between its DNA-binding and ligand-binding domains.
PMID:30166540
Comment on "Innovative scattering analysis shows that hydrophobic disordered proteins are expanded in water".
PMID:30166461
Structural complexity of the co-chaperone SGTA: a conserved C-terminal region is implicated in dimerization and substrate quality control.
PMID:29996828
Small but large enough: structural properties of armless mitochondrial tRNAs from the nematode Romanomermis culicivorax.
PMID:29986062
Redox Modulation of Oligomeric State in Proline Utilization A.
PMID:29925020
Machine Learning Methods for X-Ray Scattering Data Analysis from Biomacromolecular Solutions.
PMID:29874600
Structural biology data archiving - where we are and what lies ahead.
PMID:29749603
Consensus Bayesian assessment of protein molecular mass from solution X-ray scattering data.
PMID:29739979
Structure and hydrodynamics of a DNA G-quadruplex with a cytosine bulge.
PMID:29718405
UNRES server for physics-based coarse-grained simulations and prediction of protein structure, dynamics and thermodynamics.
PMID:29718313
Development of a Prototype System for Archiving Integrative/Hybrid Structure Models of Biological Macromolecules.
PMID:29657133
An N-terminally truncated form of cyclic GMP-dependent protein kinase Iα (PKG Iα) is monomeric and autoinhibited and provides a model for activation.
PMID:29602907
Dystrophin's central domain forms a complex filament that becomes disorganized by in-frame deletions.
PMID:29535188
Determination of protein oligomeric structure from small-angle X-ray scattering.
PMID:29352739
Structural Dynamics Control Allosteric Activation of Cytohesin Family Arf GTPase Exchange Factors.
PMID:29276036
Structural and functional dissection of the DH and PH domains of oncogenic Bcr-Abl tyrosine kinase.
PMID:29235475
A novel Porphyromonas gingivalis enzyme: An atypical dipeptidyl peptidase III with an ARM repeat domain.
PMID:29190734
PDBe: towards reusable data delivery infrastructure at protein data bank in Europe.
PMID:29126160
Relative merits and limiting factors for x-ray and electron microscopy of thick, hydrated organic materials.
PMID:29073575
New tools and functions in data-out activities at Protein Data Bank Japan (PDBj).
PMID:28815765
Highly selective tungstate transporter protein TupA from Desulfovibrio alaskensis G20.
PMID:28724964
A shape-shifting redox foldase contributes to Proteus mirabilis copper resistance.
PMID:28722010
Biophysical investigation of type A PutAs reveals a conserved core oligomeric structure.
PMID:28710792
Interactions between LHX3- and ISL1-family LIM-homeodomain transcription factors are conserved in Caenorhabditis elegans.
PMID:28676648
Skeletal Dysplasia Mutations Effect on Human Filamins' Structure and Mechanosensing.
PMID:28652603
Conformational plasticity and evolutionary analysis of the myotilin tandem Ig domains.
PMID:28638118
Protein Data Bank (PDB): The Single Global Macromolecular Structure Archive.
PMID:28573592
Combining NMR and small angle X-ray scattering for the study of biomolecular structure and dynamics.
PMID:28501583
Human βB2-Crystallin Forms a Face-en-Face Dimer in Solution: An Integrated NMR and SAXS Study.
PMID:28238532
The Shigella Virulence Factor IcsA Relieves N-WASP Autoinhibition by Displacing the Verprolin Homology/Cofilin/Acidic (VCA) Domain.
PMID:27881679
Engineering a trifunctional proline utilization A chimaera by fusing a DNA-binding domain to a bifunctional PutA.
PMID:27742866
Preparing monodisperse macromolecular samples for successful biological small-angle X-ray and neutron-scattering experiments.
PMID:27711050
Assessing heterogeneity in oligomeric AAA+ machines.
PMID:27669691
Intrinsic Disorder of the C-Terminal Domain of Drosophila Methoprene-Tolerant Protein.
PMID:27657508
A Structure-free Method for Quantifying Conformational Flexibility in proteins.
PMID:27358108
Immunosuppressive Yersinia Effector YopM Binds DEAD Box Helicase DDX3 to Control Ribosomal S6 Kinase in the Nucleus of Host Cells.
PMID:27300509
Analysis of self-assembly of S-layer protein slp-B53 from Lysinibacillus sphaericus.
PMID:27270294
Sampling Enrichment toward Target Structures Using Hybrid Molecular Dynamics-Monte Carlo Simulations.
PMID:27227775
X-Ray Solution Scattering Study of Four Escherichia coli Enzymes Involved in Stationary-Phase Metabolism.
PMID:27227414
Structure of ThiM from Vitamin B1 biosynthetic pathway of Staphylococcus aureus - Insights into a novel pro-drug approach addressing MRSA infections.
PMID:26960569
Hybrid Approaches to Structural Characterization of Conformational Ensembles of Complex Macromolecular Systems Combining NMR Residual Dipolar Couplings and Solution X-ray Scattering.
PMID:26739383
Structural Characterization of the Extracellular Domain of CASPR2 and Insights into Its Association with the Novel Ligand Contactin1.
PMID:26721881
RAID3--An interleukin-6 receptor-binding aptamer with post-selective modification-resistant affinity.
PMID:26383776
Flexible Structure of Peptide-Bound Filamin A Mechanosensor Domain Pair 20-21.
PMID:26322797
Dimerization-Induced Allosteric Changes of the Oxyanion-Hole Loop Activate the Pseudorabies Virus Assemblin pUL26N, a Herpesvirus Serine Protease.
PMID:26161660
Outcome of the First wwPDB Hybrid/Integrative Methods Task Force Workshop.
PMID:26095030
A posteriori determination of the useful data range for small-angle scattering experiments on dilute monodisperse systems.
PMID:25995844
pyDockSAXS: protein-protein complex structure by SAXS and computational docking.
PMID:25897115
WAXSiS: a web server for the calculation of SAXS/WAXS curves based on explicit-solvent molecular dynamics.
PMID:25855813
The 2015 Nucleic Acids Research Database Issue and molecular biology database collection.
PMID:25593347