R-BIND

An Interactive Database for Exploring and Developing RNA-Targeted Chemical Probes. R-BIND: The RNA-Targeted BIoactive ligaNd Database. The dataset includes only bioactive ligands with demonstrated activity in cell culture and/or animal models. This database is expected to expedite the discovery of RNA chemical probes. R-BIND was created by the Hargrove Lab at Duke University

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R-BIND: An Interactive Database for Exploring and Developing RNA-Targeted Chemical Probes
PMID: 31589399

metasource: bio.tools
version: extracted_at: 2022-11-04T11:29:40.634020

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• R-BIND: An Interactive Database for Exploring and Developing RNA-Targeted Chemical Probes PubMed citations: 17.

  17 articles citing: R-BIND: An Interactive Database for Exploring and Developing RNA-Targeted Chemical Probes

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  RNALigands: a database and web server for RNA-ligand interactions. PMID:34732566

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  Screening of Minimalist Noncanonical Sites in Duplex DNA and RNA Reveals Context and Motif-Selective Binding by Fluorogenic Base Probes. PMID:34693570

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  SMART v1.0: A Database for Small Molecules with Functional Implications in Plants. PMID:34648133

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  RPocket: an intuitive database of RNA pocket topology information with RNA-ligand data resources. PMID:34496744

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  DrugPred_RNA-A Tool for Structure-Based Druggability Predictions for RNA Binding Sites. PMID:34286972

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  Programmable technologies to manipulate gene expression at the RNA level. PMID:33930627

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  Targeting RNA with small molecules: from fundamental principles towards the clinic. PMID:33458725

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  Frameworks for targeting RNA with small molecules. PMID:33334887

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  Small molecule-RNA targeting: starting with the fundamentals. PMID:33201954

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  New Chemical Modalities Enabling Specific RNA Targeting and Degradation: Application to SARS-CoV-2 RNA. PMID:33140031

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  Understanding the characteristics of nonspecific binding of drug-like compounds to canonical stem-loop RNAs and their implications for functional cellular assays. PMID:33028652

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  Specific suppression of D-RNA G-quadruplex-protein interaction with an L-RNA aptamer. PMID:32976590

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  Unnatural bases for recognition of noncoding nucleic acid interfaces. PMID:32969496

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  Expanded DNA and RNA Trinucleotide Repeats in Myotonic Dystrophy Type 1 Select Their Own Multitarget, Sequence-Selective Inhibitors. PMID:32856901

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  Target-Directed Approaches for Screening Small Molecules against RNA Targets. PMID:32419578

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  How We Think about Targeting RNA with Small Molecules. PMID:32212706

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  Template-guided selection of RNA ligands using imine-based dynamic combinatorial chemistry. PMID:32104839

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probes and primers

metasource: bio.tools
version: extracted_at: 2022-11-04T11:29:40.634020

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cheminformatics

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version: extracted_at: 2022-11-04T11:29:40.634020

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small molecules

metasource: bio.tools
version: extracted_at: 2022-11-04T11:29:40.634020

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functional, regulatory and non-coding rna

metasource: bio.tools
version: extracted_at: 2022-11-04T11:29:40.634020

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medicinal chemistry

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probes and primers cheminformatics small molecule functional, regulatory and non-coding rna medicinal chemistry