The Protein pKa Database (PPD) v1.0 provides a compendium of protein residue-specific ionisation equilibria (pKa values), as collated from the primary literature, in the form of a web-accessible postgreSQL relational database. Ionizable residues play key roles in the molecular mechanisms that underlie many biological phenomena, including protein folding and enzyme catalysis. The PPD database serves as a general protein pKa archive and as a source of data that allows for the development and improvement of pKa prediction systems. The database is accessed through an HTML interface, which offers two fast, efficient search methods: an amino acid-based query and a BLAST search. Entries also give details of experimental techniques and links to other key databases, such as NCBI and the Protein Data Bank, providing the user with considerable background information. The database can be found at the following URL: http://www.ddg-pharmfac.net/ppd/PPD/pKahomepage.htm.
protein sequence protein properties transcription factors and regulatory sites data submission, annotation and curation model organisms gene transcripts