Exposure to GABAA Receptor Antagonist Picrotoxin in Pregnant Mice Causes Autism-Like Behaviors and Aberrant Gene Expression in Offspring.
PMID:35185658
A gene expression biomarker for predictive toxicology to identify chemical modulators of NF-κB.
PMID:35108274
GCN5 maintains muscle integrity by acetylating YY1 to promote dystrophin expression.
PMID:35024765
The role of epithelial progesterone receptor isoforms in embryo implantation.
PMID:34934913
Repurposing haloperidol for the treatment of rheumatoid arthritis: an integrative approach using data mining techniques.
PMID:34589142
H3K4 di-methylation governs smooth muscle lineage identity and promotes vascular homeostasis by restraining plasticity.
PMID:34582749
Epigenome-Wide DNA Methylation and Pesticide Use in the Agricultural Lung Health Study.
PMID:34516295
Similarities of developmental gene expression changes in the brain between human and experimental animals: rhesus monkey, mouse, Zebrafish, and Drosophila.
PMID:34493287
Cobalt-induced oxidative stress contributes to alveolar/bronchiolar carcinogenesis in B6C3F1/N mice.
PMID:34468815
Profiling of Adipose and Skeletal Muscle in Human Pancreatic Cancer Cachexia Reveals Distinct Gene Profiles with Convergent Pathways.
PMID:33923976
Malignant Pleural Mesothelioma Interactome with 364 Novel Protein-Protein Interactions.
PMID:33916178
Identifying Molecular Signatures of Distinct Modes of Collective Migration in Response to the Microenvironment Using Three-Dimensional Breast Cancer Models.
PMID:33804802
Development and validation of the TGx-HDACi transcriptomic biomarker to detect histone deacetylase inhibitors in human TK6 cells.
PMID:33770205
Higher PGD2 production by synovial mast cells from rheumatoid arthritis patients compared with osteoarthritis patients via miR-199a-3p/prostaglandin synthetase 2 axis.
PMID:33707464
TGx-DDI, a Transcriptomic Biomarker for Genotoxicity Hazard Assessment of Pharmaceuticals and Environmental Chemicals.
PMID:33693359
Transcriptome from opaque cornea of Fanconi anemia patient uncovers fibrosis and two connected players.
PMID:33552906
Aberrant Dyskerin Expression Is Related to Proliferation and Poor Survival in Endometrial Cancer.
PMID:33450922
A Comparison of Gene Expression Changes in the Blood of Individuals Consuming Diets Supplemented with Olives, Nuts or Long-Chain Omega-3 Fatty Acids.
PMID:33302351
Human Endometrial Carcinogenesis Is Associated with Significant Reduction in Long Non-Coding RNA, TERRA.
PMID:33217925
Meta-analysis of global and high throughput public gene array data for robust vascular gene expression discovery in chronic rhinosinusitis: Implications in controlled release.
PMID:33144181
Thresholds Derived From Common Measures in Rat Studies Are Predictive of Liver Tumorigenic Chemicals.
PMID:33084515
FGF13 interaction with SHCBP1 activates AKT-GSK3α/β signaling and promotes the proliferation of A549 cells.
PMID:33064958
Therapeutic Opportunities for Intestinal Angioectasia- Targeting PPARγ and Oxidative Stress.
PMID:33048460
Mining a human transcriptome database for chemical modulators of NRF2.
PMID:32986742
Induction of ER Stress by an AAV5 BDD FVIII Construct Is Dependent on the Strength of the Hepatic-Specific Promoter.
PMID:32775496
Potentially repurposable drugs for COVID-19 identified from SARS-CoV-2 Host Protein Interactome.
PMID:32702734
Interactome of SARS-CoV-2 / nCoV19 modulated host proteins with computationally predicted PPIs.
PMID:32702714
A Set of Six Gene Expression Biomarkers Identify Rat Liver Tumorigens in Short-term Assays.
PMID:32603430
A human lung tumor microenvironment interactome identifies clinically relevant cell-type cross-talk.
PMID:32381040
Transcriptomic and Network Analysis Identifies Shared and Unique Pathways across Dementia Spectrum Disorders.
PMID:32192109
Uterine Patterning, Endometrial Gland Development, and Implantation Failure in Mice Exposed Neonatally to Genistein.
PMID:32186404
ORSO (Online Resource for Social Omics): A data-driven social network connecting scientists to genomics datasets.
PMID:31978042
In Vitro, In Vivo, and In Silico Methods for Assessment of Muscle Size and Muscle Growth Regulation.
PMID:31939770
Transcriptomic and Network Analysis Highlight the Association of Diabetes at Different Stages of Alzheimer's Disease.
PMID:31849586
Integrative analysis of clinical and bioinformatics databases to identify anticancer properties of digoxin.
PMID:31719612
Peripheral loss of EphA4 ameliorates TBI-induced neuroinflammation and tissue damage.
PMID:31711546
Meta-Analysis of Gene Expression Changes in the Blood of Patients with Mild Cognitive Impairment and Alzheimer's Disease Dementia.
PMID:31671574
Evaluation of Serum Biomarkers (FGF-2, HGF, MIF and PTN) in Patients With Testicular Germ Cell Cancer.
PMID:31662522
Hippocampal Subregions Express Distinct Dendritic Transcriptomes that Reveal Differences in Mitochondrial Function in CA2.
PMID:31597108
Potentially repurposable drugs for schizophrenia identified from its interactome.
PMID:31481665
SHCBP1 regulates apoptosis in lung cancer cells through phosphatase and tensin homolog.
PMID:31423258
Pharmacological inhibition of NPY receptors illustrates dissociable features of experimental colitis in the mouse DSS model: Implications for preclinical evaluation of efficacy in an inflammatory bowel disease model.
PMID:31369588
Transgenic mice overexpressing miR-137 in the brain show schizophrenia-associated behavioral deficits and transcriptome profiles.
PMID:31361772
Axonal pathology in hPSC-based models of Parkinson's disease results from loss of Nrf2 transcriptional activity at the Map1b gene locus.
PMID:31235589
An Ontology to Standardize Research Output of Nutritional Epidemiology: From Paper-Based Standards to Linked Content.
PMID:31181762
RNA sequencing of intestinal mucosa reveals novel pathways functionally linked to celiac disease pathogenesis.
PMID:30998704
Frequent Modulation of the Sterol Regulatory Element Binding Protein (SREBP) by Chemical Exposure in the Livers of Rats.
PMID:30931410
mTOR inhibition affects Yap1-β-catenin-induced hepatoblastoma growth and development.
PMID:30863496
Transcriptomic evidence for immaturity induced by antidepressant fluoxetine in the hippocampus and prefrontal cortex.
PMID:30772953
Isolation and characterization of patient-derived CNS metastasis-associated stromal cell lines.
PMID:30700832
Transcriptomic immaturity inducible by neural hyperexcitation is shared by multiple neuropsychiatric disorders.
PMID:30675529
Systems Analysis of Transcriptomic and Proteomic Profiles Identifies Novel Regulation of Fibrotic Programs by miRNAs in Pulmonary Fibrosis Fibroblasts.
PMID:30501089
Abnormally located SSEA1+/SOX9+ endometrial epithelial cells with a basalis-like phenotype in the eutopic functionalis layer may play a role in the pathogenesis of endometriosis.
PMID:30496412
Assessment of the performance of the TGx-DDI biomarker to detect DNA damage-inducing agents using quantitative RT-PCR in TK6 cells.
PMID:30488505
A computational strategy for finding novel targets and therapeutic compounds for opioid dependence.
PMID:30403753
RND1 regulates migration of human glioblastoma stem-like cells according to their anatomical localization and defines a prognostic signature in glioblastoma.
PMID:30333910
Using a gene expression biomarker to identify DNA damage-inducing agents in microarray profiles.
PMID:30329178
An integrative approach using real-world data to identify alternative therapeutic uses of existing drugs.
PMID:30300381
Resveratrol Improves Recovery and Survival of Diet-Induced Obese Mice Undergoing Extended Major (80%) Hepatectomy.
PMID:30284135
Chemical Activation of the Constitutive Androstane Receptor Leads to Activation of Oxidant-Induced Nrf2.
PMID:30203046
High AGR2 protein is a feature of low grade endometrial cancer cells.
PMID:30140383
Activation of Nrf2 in the liver is associated with stress resistance mediated by suppression of the growth hormone-regulated STAT5b transcription factor.
PMID:30114225
Identification of Androgen Receptor Modulators in a Prostate Cancer Cell Line Microarray Compendium.
PMID:30085300
Chemogenomics Systems Pharmacology Mapping of Potential Drug Targets for Treatment of Traumatic Brain Injury.
PMID:30014763
Multi-omics monitoring of drug response in rheumatoid arthritis in pursuit of molecular remission.
PMID:30013029
Early Transcriptional Responses After Dengue Vaccination Mirror the Response to Natural Infection and Predict Neutralizing Antibody Titers.
PMID:30010906
Does human endometrial LGR5 gene expression suggest the existence of another hormonally regulated epithelial stem cell niche?
PMID:29648645
A novel two-score system for interferon status segregates autoimmune diseases and correlates with clinical features.
PMID:29643425
The ablation of the matricellular protein EMILIN2 causes defective vascularization due to impaired EGFR-dependent IL-8 production affecting tumor growth.
PMID:29483644
Meloxicam increases epidermal growth factor receptor expression improving survival after hepatic resection in diet-induced obese mice.
PMID:29361369
Identity crisis in pulmonary arterial hypertension.
PMID:29206084
NitroSynapsin therapy for a mouse MEF2C haploinsufficiency model of human autism.
PMID:29133852
Microfluidic chest cavities reveal that transmural pressure controls the rate of lung development.
PMID:29084801
Loss of NLRX1 Exacerbates Neural Tissue Damage and NF-κB Signaling following Brain Injury.
PMID:28993512
Melanoma antigen A12 regulates cell cycle via tumor suppressor p21 expression.
PMID:28978129
From the Cover: Genomic Effects of Androstenedione and Sex-Specific Liver Cancer Susceptibility in Mice.
PMID:28973534
Arid1b Haploinsufficiency Causes Abnormal Brain Gene Expression and Autism-Related Behaviors in Mice.
PMID:28867767
Changes in Global Transcriptional Profiling of Women Following Obesity Surgery Bypass.
PMID:28735374
Editor's Highlight: Transcriptome Profiling Reveals Bisphenol A Alternatives Activate Estrogen Receptor Alpha in Human Breast Cancer Cells.
PMID:28591870
Generating testable hypotheses for schizophrenia and rheumatoid arthritis pathogenesis by integrating epidemiological, genomic, and protein interaction data.
PMID:28560257
PPARα-independent transcriptional targets of perfluoroalkyl acids revealed by transcript profiling.
PMID:28558994
Blood Transcriptomic Meta-analysis Identifies Dysregulation of Hemoglobin and Iron Metabolism in Parkinson' Disease.
PMID:28424608
Modeling vascular inflammation and atherogenicity after inhalation of ambient levels of ozone: exploratory lessons from transcriptomics.
PMID:28412860
Exosomal MicroRNA Transfer Into Macrophages Mediates Cellular Postconditioning.
PMID:28411247
Mathematical deconvolution uncovers the genetic regulatory signal of cancer cellular heterogeneity on resistance to paclitaxel.
PMID:28386641
Transcriptomic immaturity of the hippocampus and prefrontal cortex in patients with alcoholism.
PMID:28295046
Enhanced Mucosal Defense and Reduced Tumor Burden in Mice with the Compromised Negative Regulator IRAK-M.
PMID:27939424
Identification of an Efficient Gene Expression Panel for Glioblastoma Classification.
PMID:27855170
Coinhibition of the deubiquitinating enzymes, USP14 and UCHL5, with VLX1570 is lethal to ibrutinib- or bortezomib-resistant Waldenstrom macroglobulinemia tumor cells.
PMID:27813535
CD8+ T Cells and Macrophages Regulate Pathogenesis in a Mouse Model of Middle East Respiratory Syndrome.
PMID:27795435
Integrative transcriptomic meta-analysis of Parkinson's disease and depression identifies NAMPT as a potential blood biomarker for de novo Parkinson's disease.
PMID:27680512
Hepatic transcriptomic alterations for N,N-dimethyl-p-toluidine (DMPT) and p-toluidine after 5-day exposure in rats.
PMID:27638505
Human Cathelicidin Compensates for the Role of Apolipoproteins in Hepatitis C Virus Infectious Particle Formation.
PMID:27440892
LATS2 Positively Regulates Polycomb Repressive Complex 2.
PMID:27434182
Technology-Based Innovations to Foster Personalized Healthy Lifestyles and Well-Being: A Targeted Review.
PMID:27342137
Nonessential Role for the NLRP1 Inflammasome Complex in a Murine Model of Traumatic Brain Injury.
PMID:27199506
Developing a Gene Biomarker at the Tipping Point of Adaptive and Adverse Responses in Human Bronchial Epithelial Cells.
PMID:27195669
Transcriptional profiling of the mouse hippocampus supports an NMDAR-mediated neurotoxic mode of action for benzo[a]pyrene.
PMID:27195522
Lipoprotein Receptors Redundantly Participate in Entry of Hepatitis C Virus.
PMID:27152966
Integrative genomic deconvolution of rheumatoid arthritis GWAS loci into gene and cell type associations.
PMID:27140173
NLRX1 suppresses tumorigenesis and attenuates histiocytic sarcoma through the negative regulation of NF-κB signaling.
PMID:27105514
Molecular Changes in the Nasal Cavity after N, N-dimethyl-p-toluidine Exposure.
PMID:27099258
Identification of modulators of autophagic flux in an image-based high content siRNA screen.
PMID:27050463
Disruption of STAT5b-Regulated Sexual Dimorphism of the Liver Transcriptome by Diverse Factors Is a Common Event.
PMID:26959975
Chemical and Hormonal Effects on STAT5b-Dependent Sexual Dimorphism of the Liver Transcriptome.
PMID:26959237
Moving Toward Integrating Gene Expression Profiling Into High-Throughput Testing: A Gene Expression Biomarker Accurately Predicts Estrogen Receptor α Modulation in a Microarray Compendium.
PMID:26865669
Identification of the dopamine transporter SLC6A3 as a biomarker for patients with renal cell carcinoma.
PMID:26831905
Fish connectivity mapping: linking chemical stressors by their mechanisms of action-driven transcriptomic profiles.
PMID:26822894
A common molecular signature in ASD gene expression: following Root 66 to autism.
PMID:26731442
Luminal long non-coding RNAs regulated by estrogen receptor alpha in a ligand-independent manner show functional roles in breast cancer.
PMID:26621851
Aberrant Activation of Notch Signaling Inhibits PROX1 Activity to Enhance the Malignant Behavior of Thyroid Cancer Cells.
PMID:26609053
Cancer RNA-Seq Nexus: a database of phenotype-specific transcriptome profiling in cancer cells.
PMID:26602695
Carbon black nanoparticles induce biphasic gene expression changes associated with inflammatory responses in the lungs of C57BL/6 mice following a single intratracheal instillation.
PMID:26551751
Merkel cell polyomavirus T antigens promote cell proliferation and inflammatory cytokine gene expression.
PMID:26385761
Mining the Archives: A Cross-Platform Analysis of Gene Expression Profiles in Archival Formalin-Fixed Paraffin-Embedded Tissues.
PMID:26361796
Specificity protein (Sp) transcription factors and metformin regulate expression of the long non-coding RNA HULC.
PMID:26317792
Evasion of affinity-based selection in germinal centers by Epstein-Barr virus LMP2A.
PMID:26305967
Pharmacokinetics and Pharmacodynamics with Extended Dosing of CC-486 in Patients with Hematologic Malignancies.
PMID:26296092
Genomic Profiling Reveals Unique Molecular Alterations in Hepatoblastomas and Adjacent Hepatocellular Carcinomas in B6C3F1 Mice.
PMID:26289556
Screening a mouse liver gene expression compendium identifies modulators of the aryl hydrocarbon receptor (AhR).
PMID:26215100
ZNF555 protein binds to transcriptional activator site of 4qA allele and ANT1: potential implication in Facioscapulohumeral dystrophy.
PMID:26184877
An interactive web application for the dissemination of human systems immunology data.
PMID:26088622
Identification of chemical modulators of the constitutive activated receptor (CAR) in a gene expression compendium.
PMID:25949234
Technical guide for applications of gene expression profiling in human health risk assessment of environmental chemicals.
PMID:25944780
The long non-coding RNA HOTTIP enhances pancreatic cancer cell proliferation, survival and migration.
PMID:25912306
Drug screen in patient cells suggests quinacrine to be repositioned for treatment of acute myeloid leukemia.
PMID:25885427
Effective Targeting of Estrogen Receptor-Negative Breast Cancers with the Protein Kinase D Inhibitor CRT0066101.
PMID:25852060
Meta-analysis of gene expression profiles indicates genes in spliceosome pathway are up-regulated in hepatocellular carcinoma (HCC).
PMID:25731616
The NLRP1 inflammasome attenuates colitis and colitis-associated tumorigenesis.
PMID:25725098
Regulation of epithelial-mesenchymal transition in breast cancer cells by cell contact and adhesion.
PMID:25698877
Expression and functional role of orphan receptor GPR158 in prostate cancer growth and progression.
PMID:25693195
Identification of modulators of the nuclear receptor peroxisome proliferator-activated receptor α (PPARα) in a mouse liver gene expression compendium.
PMID:25689681
Silencing LRH-1 in colon cancer cell lines impairs proliferation and alters gene expression programs.
PMID:25675535
Reply to Warren et al. and Shay et al.: Commonalities across species do exist and are potentially important.
PMID:25540421
Amphipathic α-helices in apolipoproteins are crucial to the formation of infectious hepatitis C virus particles.
PMID:25502789
Caspase-11 attenuates gastrointestinal inflammation and experimental colitis pathogenesis.
PMID:25414099
Protein interaction networks reveal novel autism risk genes within GWAS statistical noise.
PMID:25409314
Hope for GWAS: relevant risk genes uncovered from GWAS statistical noise.
PMID:25268625
Identification of the transcription factor ZEB1 as a central component of the adipogenic gene regulatory network.
PMID:25163748
Unexpected phenotype of mice lacking Shcbp1, a protein induced during T cell proliferation.
PMID:25153088
The concordance between RNA-seq and microarray data depends on chemical treatment and transcript abundance.
PMID:25150839
Genomic responses in mouse models greatly mimic human inflammatory diseases.
PMID:25092317
The hypoxia-inducible epigenetic regulators Jmjd1a and G9a provide a mechanistic link between angiogenesis and tumor growth.
PMID:25071150
Activin A balance regulates epithelial invasiveness and tumorigenesis.
PMID:25068654
Characterization of functional reprogramming during osteoclast development using quantitative proteomics and mRNA profiling.
PMID:25044017
Functional genomics identifies novel genes essential for clear cell renal cell carcinoma tumor cell proliferation and migration.
PMID:24979721
Neuronal pentraxin 2 supports clear cell renal cell carcinoma by activating the AMPA-selective glutamate receptor-4.
PMID:24962026
STAT1-induced ASPP2 transcription identifies a link between neuroinflammation, cell polarity, and tumor suppression.
PMID:24958857
Biochemical characterization of human gluconokinase and the proposed metabolic impact of gluconic acid as determined by constraint based metabolic network analysis.
PMID:24896608
Transcriptomic evidence for immaturity of the prefrontal cortex in patients with schizophrenia.
PMID:24886351
Innate host defense requires TFEB-mediated transcription of cytoprotective and antimicrobial genes.
PMID:24882217
Tumor cell-derived MMP3 orchestrates Rac1b and tissue alterations that promote pancreatic adenocarcinoma.
PMID:24850902
ROS-induced epithelial-mesenchymal transition in mammary epithelial cells is mediated by NF-kB-dependent activation of Snail.
PMID:24811539
Tumor cell-produced matrix metalloproteinase 9 (MMP-9) drives malignant progression and metastasis of basal-like triple negative breast cancer.
PMID:24811362
Increasing consistency of disease biomarker prediction across datasets.
PMID:24740471
Notch signaling genes: myogenic DNA hypomethylation and 5-hydroxymethylcytosine.
PMID:24670287
Novel permissive cell lines for complete propagation of hepatitis C virus.
PMID:24599999
The CO-Regulation Database (CORD): a tool to identify coordinately expressed genes.
PMID:24599084
Global meta-analysis of transcriptomics studies.
PMID:24586684
Alveolar macrophages infected with Ames or Sterne strain of Bacillus anthracis elicit differential molecular expression patterns.
PMID:24516547
Nitrite reductase and nitric-oxide synthase activity of the mitochondrial molybdopterin enzymes mARC1 and mARC2.
PMID:24500710
Cell cycle-dependent Rho GTPase activity dynamically regulates cancer cell motility and invasion in vivo.
PMID:24386239
Isogenic human iPSC Parkinson's model shows nitrosative stress-induced dysfunction in MEF2-PGC1α transcription.
PMID:24290359
Transcriptomic analysis of genetically defined autism candidate genes reveals common mechanisms of action.
PMID:24238429
Formation of chimeric genes by copy-number variation as a mutational mechanism in schizophrenia.
PMID:24094746
CellMinerHCC: a microarray-based expression database for hepatocellular carcinoma cell lines.
PMID:24016071
Calpastatin gene (CAST) is not associated with late onset sporadic Parkinson's disease in the Han Chinese population.
PMID:23951044
Distinctive patterns of DNA methylation associated with Parkinson disease: identification of concordant epigenetic changes in brain and peripheral blood leukocytes.
PMID:23907097
Confero: an integrated contrast data and gene set platform for computational analysis and biological interpretation of omics data.
PMID:23895370
Proteolysis controls endogenous substance P levels.
PMID:23894327
PGMRA: a web server for (phenotype x genotype) many-to-many relation analysis in GWAS.
PMID:23761451
Human TREX component Thoc5 affects alternative polyadenylation site choice by recruiting mammalian cleavage factor I.
PMID:23685434
Integrating murine gene expression studies to understand obstructive lung disease due to chronic inhaled endotoxin.
PMID:23675439
Synaptosomal-associated protein 25 mutation induces immaturity of the dentate granule cells of adult mice.
PMID:23497716
Genome-wide analysis of LXRα activation reveals new transcriptional networks in human atherosclerotic foam cells.
PMID:23393188
Temporal dynamics of the transcriptional response to dengue virus infection in Nicaraguan children.
PMID:23285306
Gene expression profiling to identify potentially relevant disease outcomes and support human health risk assessment for carbon black nanoparticle exposure.
PMID:23146762
CellLineNavigator: a workbench for cancer cell line analysis.
PMID:23118487
An in vivo screen of secreted proteins identifies adiponectin as a regulator of murine cutaneous wound healing.
PMID:23096717
Dynamic distribution of linker histone H1.5 in cellular differentiation.
PMID:22956909
Differential transcriptomic analysis of spontaneous lung tumors in B6C3F1 mice: comparison to human non-small cell lung cancer.
PMID:22688403
Genome-scale analysis of DNA methylation in lung adenocarcinoma and integration with mRNA expression.
PMID:22613842
Expression of microRNA miR-122 facilitates an efficient replication in nonhepatic cells upon infection with hepatitis C virus.
PMID:22593164
Matrix metalloproteinase-10 is required for lung cancer stem cell maintenance, tumor initiation and metastatic potential.
PMID:22545096
NLRP12 suppresses colon inflammation and tumorigenesis through the negative regulation of noncanonical NF-κB signaling.
PMID:22503542
An animal model of MYC-driven medulloblastoma.
PMID:22340590
Antipsychotics activate the TGFβ pathway effector SMAD3.
PMID:22290122
Identification of aberrant pathways and network activities from high-throughput data.
PMID:22287794
Characterization of polybrominated diphenyl ether toxicity in Wistar Han rats and use of liver microarray data for predicting disease susceptibilities.
PMID:22267650
Comprehensive literature review and statistical considerations for microarray meta-analysis.
PMID:22262733
ProKinO: an ontology for integrative analysis of protein kinases in cancer.
PMID:22194913
Data-driven information retrieval in heterogeneous collections of transcriptomics data links SIM2s to malignant pleural mesothelioma.
PMID:22106335
Matrix metalloproteinase-10 promotes Kras-mediated bronchio-alveolar stem cell expansion and lung cancer formation.
PMID:22022614
Discovery of nonsteroidal anti-inflammatory drug and anticancer drug enhancing reprogramming and induced pluripotent stem cell generation.
PMID:21898684
Homozygosity mapping and targeted genomic sequencing reveal the gene responsible for cerebellar hypoplasia and quadrupedal locomotion in a consanguineous kindred.
PMID:21885617
Global gene profiling of spontaneous hepatocellular carcinoma in B6C3F1 mice: similarities in the molecular landscape with human liver cancer.
PMID:21571946
In search of the Golden Fleece: unraveling principles of morphogenesis by studying the integrative biology of skin appendages.
PMID:21437328