MitoCheck
MitoCheck aims to integrate information on cellular function of human genes while giving access to supporting information such as microscopy images of phenotypes.
Description
More detailed information about this field from each metasource.
MitoCheck aims to integrate information on cellular function of human genes while giving access to supporting information such as microscopy images of phenotypes.
metasource: Fairsharing.orgversion: FAIRsharing.org: MitoCheck; MitoCheck; DOI: https://doi.org/10.25504/FAIRsharing.j4ebq1; Last edited: April 26, 2021, 4:04 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
Webpage:
http://www.mitocheck.orgWebpage
More detailed information about this field from each metasource.
http://www.mitocheck.org
metasource: Fairsharing.orgversion: FAIRsharing.org: MitoCheck; MitoCheck; DOI: https://doi.org/10.25504/FAIRsharing.j4ebq1; Last edited: April 26, 2021, 4:04 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
Publications:
Publications
More detailed information about this field from each metasource.
Phenotypic profiling of the human genome by time-lapse microscopy reveals cell division genes
PMID: 20360735
metasource: Fairsharing.org
version: FAIRsharing.org: MitoCheck; MitoCheck; DOI: https://doi.org/10.25504/FAIRsharing.j4ebq1; Last edited: April 26, 2021, 4:04 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
Systematic analysis of human protein complexes identifies chromosome segregation proteins
PMID: 20360068
metasource: Fairsharing.org
version: FAIRsharing.org: MitoCheck; MitoCheck; DOI: https://doi.org/10.25504/FAIRsharing.j4ebq1; Last edited: April 26, 2021, 4:04 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
Experimental and computational framework for a dynamic protein atlas of human cell division
PMID: 30202089
metasource: Fairsharing.org
version: FAIRsharing.org: MitoCheck; MitoCheck; DOI: https://doi.org/10.25504/FAIRsharing.j4ebq1; Last edited: April 26, 2021, 4:04 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
Publications
More detailed information about this field from each metasource.
Phenotypic profiling of the human genome by time-lapse microscopy reveals cell division genes
PMID: 20360735
metasource: Fairsharing.org
version: FAIRsharing.org: MitoCheck; MitoCheck; DOI: https://doi.org/10.25504/FAIRsharing.j4ebq1; Last edited: April 26, 2021, 4:04 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
Systematic analysis of human protein complexes identifies chromosome segregation proteins
PMID: 20360068
metasource: Fairsharing.org
version: FAIRsharing.org: MitoCheck; MitoCheck; DOI: https://doi.org/10.25504/FAIRsharing.j4ebq1; Last edited: April 26, 2021, 4:04 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
Experimental and computational framework for a dynamic protein atlas of human cell division
PMID: 30202089
metasource: Fairsharing.org
version: FAIRsharing.org: MitoCheck; MitoCheck; DOI: https://doi.org/10.25504/FAIRsharing.j4ebq1; Last edited: April 26, 2021, 4:04 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
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Phenotypic profiling of the human genome by time-lapse microscopy reveals cell division genes
PubMed citations: 422.
422 articles citing: Phenotypic profiling of the human genome by time-lapse microscopy reveals cell division genes
Mitosis, Focus on Calcium. PMID:35784871
A commercial ARHGEF17/TEM4 antibody cross-reacts with Nuclear Mitotic Apparatus protein 1 (NuMA). PMID:35776709
Fine-tuning cell organelle dynamics during mitosis by small GTPases. PMID:35759087
The Interplay of Cohesin and RNA Processing Factors: The Impact of Their Alterations on Genome Stability. PMID:35409298
Mitotic spindle formation in the absence of Polo kinase. PMID:35286199
The N-terminal domain of TET1 promotes the formation of dense chromatin regions refractory to transcription. PMID:35235010
The PRP19 Ubiquitin Ligase, Standing at the Cross-Roads of mRNA Processing and Genome Stability. PMID:35205626
CFTR interactome mapping using the mammalian membrane two-hybrid high-throughput screening system. PMID:35156780
DynaMorph: self-supervised learning of morphodynamic states of live cells. PMID:35138913
Pooled genetic perturbation screens with image-based phenotypes. PMID:35022620
Effects of aneuploidy on cell behaviour and function. PMID:34987171
Loss of USP28 and SPINT2 expression promotes cancer cell survival after whole genome doubling. PMID:34962618
A community-based approach to image analysis of cells, tissues and tumors. PMID:34864359
Opposing motors provide mechanical and functional robustness in the human spindle. PMID:34614397
Subcellular proteomics. PMID:34549195
Alternative splicing regulation of cell-cycle genes by SPF45/SR140/CHERP complex controls cell proliferation. PMID:34544891
Wnt signaling recruits KIF2A to the spindle to ensure chromosome congression and alignment during mitosis. PMID:34417301
An engineered transcriptional reporter of protein localization identifies regulators of mitochondrial and ER membrane protein trafficking in high-throughput CRISPRi screens. PMID:34414886
Fetal brain arrest broadens the spectrum of WDR81-related developmental brain malformations. PMID:34338917
Condensation of pericentrin proteins in human cells illuminates phase separation in centrosome assembly. PMID:34308971
High-precision targeting workflow for volume electron microscopy. PMID:34160561
Single-cell image analysis to explore cell-to-cell heterogeneity in isogenic populations. PMID:34139168
High-Resolution Analysis of Centrosome Behavior During Mitosis. PMID:34085223
Inactivating Mutations of the IK Gene Weaken Ku80/Ku70-Mediated DNA Repair and Sensitize Endometrial Cancer to Chemotherapy. PMID:34065218
Secreted midbody remnants are a class of extracellular vesicles molecularly distinct from exosomes and microparticles. PMID:33767328
Identification of small molecules that mitigate vincristine-induced neurotoxicity while sensitizing leukemia cells to vincristine. PMID:33742760
PRMT5 inhibition disrupts splicing and stemness in glioblastoma. PMID:33579912
Visual4DTracker: a tool to interact with 3D + t image stacks. PMID:33557754
Bioimage Analysis and Cell Motility. PMID:33511365
Multi-parametric characterization of drug effects on cells. PMID:33363713
Image-based profiling for drug discovery: due for a machine-learning upgrade? PMID:33353986
Machine learning-enabled multiplexed microfluidic sensors. PMID:33343782
SECAT: Quantifying Protein Complex Dynamics across Cell States by Network-Centric Analysis of SEC-SWATH-MS Profiles. PMID:33333029
A role for Cep70 in centriole amplification in multiciliated cells. PMID:33285087
Stem cell imaging through convolutional neural networks: current issues and future directions in artificial intelligence technology. PMID:33240655
OpSeF: Open Source Python Framework for Collaborative Instance Segmentation of Bioimages. PMID:33117778
The 3D Topography of Mitotic Chromosomes. PMID:32768407
Ex vivo assessment of targeted therapies in a rare metastatic epithelial-myoepithelial carcinoma. PMID:32645560
Moonlighting in Mitosis: Analysis of the Mitotic Functions of Transcription and Splicing Factors. PMID:32604778
Deubiquitinase USP47-stabilized splicing factor IK regulates the splicing of ATM pre-mRNA. PMID:32377397
Highly parallel and efficient single cell mRNA sequencing with paired picoliter chambers. PMID:32355211
A high-content RNAi screen reveals multiple roles for long noncoding RNAs in cell division. PMID:32296040
Automated 3D light-sheet screening with high spatiotemporal resolution reveals mitotic phenotypes. PMID:32295847
Hyaluronan Mediated Motility Receptor (HMMR) Encodes an Evolutionarily Conserved Homeostasis, Mitosis, and Meiosis Regulator Rather than a Hyaluronan Receptor. PMID:32231069
Microneedle manipulation of the mammalian spindle reveals specialized, short-lived reinforcement near chromosomes. PMID:32191206
Uniform intensity in multifocal microscopy using a spatial light modulator. PMID:32160259
KCML: a machine-learning framework for inference of multi-scale gene functions from genetic perturbation screens. PMID:32141232
Membrane and organelle dynamics during cell division. PMID:32034394
Phase separation of TPX2 enhances and spatially coordinates microtubule nucleation. PMID:31937751
Network of Interactions between ZIKA Virus Non-Structural Proteins and Human Host Proteins. PMID:31936331
Spatially and temporally defined lysosomal leakage facilitates mitotic chromosome segregation. PMID:31932607
On the epigenetic role of guanosine oxidation. PMID:31926624
A solid-phase transfection platform for arrayed CRISPR screens. PMID:31885201
High-Content Image-Based Single-Cell Phenotypic Analysis for the Testicular Toxicity Prediction Induced by Bisphenol A and Its Analogs Bisphenol S, Bisphenol AF, and Tetrabromobisphenol A in a Three-Dimensional Testicular Cell Co-culture Model. PMID:31750923
A feedback loop of conditionally stable circuits drives the cell cycle from checkpoint to checkpoint. PMID:31712566
Review of high-content screening applications in toxicology. PMID:31664499
Optical Pooled Screens in Human Cells. PMID:31626775
Domain-invariant features for mechanism of action prediction in a multi-cell-line drug screen. PMID:31608933
The midbody interactome reveals unexpected roles for PP1 phosphatases in cytokinesis. PMID:31586073
Poly(ADP-ribose)-dependent chromatin unfolding facilitates the association of DNA-binding proteins with DNA at sites of damage. PMID:31566235
A novel assay to screen siRNA libraries identifies protein kinases required for chromosome transmission. PMID:31515286
Smu1 and RED are required for activation of spliceosomal B complexes assembled on short introns. PMID:31409787
High-throughput time-resolved morphology screening in bacteria reveals phenotypic responses to antibiotics. PMID:31341968
From observing to predicting single-cell structure and function with high-throughput/high-content microscopy. PMID:31243141
Structural Basis of an Asymmetric Condensin ATPase Cycle. PMID:31226277
The exocyst complex and Rab5 are required for abscission by localizing ESCRT III subunits to the cytokinetic bridge. PMID:31221728
Absolute quantification of cohesin, CTCF and their regulators in human cells. PMID:31204999
Dissecting the mechanisms of cell division. PMID:31175154
Rho-dependent control of the Citron kinase, Sticky, drives midbody ring maturation. PMID:31166845
Software tools for automated transmission electron microscopy. PMID:31086343
High Expression of Human AugminComplex Submit 3 Indicates Poor Prognosis and Associates with Tumor Progression in Hepatocellular Carcinoma. PMID:31031853
Systematic proteomics of endogenous human cohesin reveals an interaction with diverse splicing factors and RNA-binding proteins required for mitotic progression. PMID:31010829
REEP3 and REEP4 determine the tubular morphology of the endoplasmic reticulum during mitosis. PMID:30995177
Calcium Sensors in Neuronal Function and Dysfunction. PMID:30833454
Splicing events in the control of genome integrity: role of SLU7 and truncated SRSF3 proteins. PMID:30657957
Centromere and Pericentromere Transcription: Roles and Regulation … in Sickness and in Health. PMID:30627137
Cholinergic Receptor Nicotinic Alpha 5 (CHRNA5) RNAi is associated with cell cycle inhibition, apoptosis, DNA damage response and drug sensitivity in breast cancer. PMID:30543688
Human nuclear RNAi-defective 2 (NRDE2) is an essential RNA splicing factor. PMID:30538148
TIAR marks nuclear G2/M transition granules and restricts CDK1 activity under replication stress. PMID:30538118
Splicing factors Sf3A2 and Prp31 have direct roles in mitotic chromosome segregation. PMID:30475206
Parts list for a microtubule depolymerising kinesin. PMID:30467119
Assembly of a parts list of the human mitotic cell cycle machinery. PMID:30452682
A computational framework to study sub-cellular RNA localization. PMID:30389932
Identification of pharmacological inhibitors of conventional protein secretion. PMID:30297865
PPP1R35 is a novel centrosomal protein that regulates centriole length in concert with the microcephaly protein RTTN. PMID:30168418
Leader of the SAC: molecular mechanisms of Mps1/TTK regulation in mitosis. PMID:30111590
The Spindle: Integrating Architecture and Mechanics across Scales. PMID:30093097
What's the Function of Connexin 32 in the Peripheral Nervous System? PMID:30042657
Systematic exploration of cell morphological phenotypes associated with a transcriptomic query. PMID:30011038
Systematic RNA-interference in primary human monocyte-derived macrophages: A high-throughput platform to study foam cell formation. PMID:30002403
Environmental properties of cells improve machine learning-based phenotype recognition accuracy. PMID:29973621
Proteomic Profiling of Microtubule Self-organization in M-phase. PMID:29970457
NEK7 regulates dendrite morphogenesis in neurons via Eg5-dependent microtubule stabilization. PMID:29899413
Nucleolar integrity during interphase supports faithful Cdk1 activation and mitotic entry. PMID:29881774
Bacterial Cytological Profiling Reveals the Mechanism of Action of Anticancer Metal Complexes. PMID:29865789
Specificity of RNAi, LNA and CRISPRi as loss-of-function methods in transcriptional analysis. PMID:29860520
Sharing and reusing cell image data. PMID:29851565
Quantitative mapping of fluorescently tagged cellular proteins using FCS-calibrated four-dimensional imaging. PMID:29844523
Comparison of Cell Arrays and Multi-Well Plates in Microscopy-Based Screening. PMID:29762489
Deep learning massively accelerates super-resolution localization microscopy. PMID:29658943
Mitotic spindle assembly and γ-tubulin localisation depend on the integral nuclear membrane protein Samp1. PMID:29514856
Quantitative proteomic and phosphoproteomic comparison of human colon cancer DLD-1 cells differing in ploidy and chromosome stability. PMID:29496963
SAM68 is required for regulation of Pumilio by the NORAD long noncoding RNA. PMID:29386330
The nonmotor adaptor HMMR dampens Eg5-mediated forces to preserve the kinetics and integrity of chromosome segregation. PMID:29386294
Visualization of human karyopherin beta-1/importin beta-1 interactions with protein partners in mitotic cells by co-immunoprecipitation and proximity ligation assays. PMID:29382863
Kinesin-6 KIF20B is required for efficient cytokinetic furrowing and timely abscission in human cells. PMID:29167382
miR-486 functions as a tumor suppressor in esophageal cancer by targeting CDK4/BCAS2. PMID:29115564
Fiat Lux: illuminating the cell cycle. PMID:29104761
Genome-scale single-cell mechanical phenotyping reveals disease-related genes involved in mitotic rounding. PMID:29097687
Deep machine learning provides state-of-the-art performance in image-based plant phenotyping. PMID:29020747
HMMR acts in the PLK1-dependent spindle positioning pathway and supports neural development. PMID:28994651
Structural Basis for a Safety-Belt Mechanism That Anchors Condensin to Chromosomes. PMID:28988770
A deep learning and novelty detection framework for rapid phenotyping in high-content screening. PMID:28954863
Spindle Misorientation of Cerebral and Cerebellar Progenitors Is a Mechanistic Cause of Megalencephaly. PMID:28943256
Solid-phase reverse transfection for intracellular delivery of functionally active proteins. PMID:28874398
Data-analysis strategies for image-based cell profiling. PMID:28858338
DNA Cross-Bridging Shapes a Single Nucleus from a Set of Mitotic Chromosomes. PMID:28841419
A 'synthetic-sickness' screen for senescence re-engagement targets in mutant cancer backgrounds. PMID:28806777
The Image Data Resource: A Bioimage Data Integration and Publication Platform. PMID:28775673
CRISPR/Cas9-mediated knockout of c-REL in HeLa cells results in profound defects of the cell cycle. PMID:28767691
High-Throughput Imaging for the Discovery of Cellular Mechanisms of Disease. PMID:28732598
A tunable refractive index matching medium for live imaging cells, tissues and model organisms. PMID:28708059
The small molecule inhibitor YK-4-279 disrupts mitotic progression of neuroblastoma cells, overcomes drug resistance and synergizes with inhibitors of mitosis. PMID:28602975
The long non-coding RNA LINC00152 is essential for cell cycle progression through mitosis in HeLa cells. PMID:28536419
DNA replication licensing factor Cdc6 and Plk4 kinase antagonistically regulate centrosome duplication via Sas-6. PMID:28447620
Hierarchical assembly of centriole subdistal appendages via centrosome binding proteins CCDC120 and CCDC68. PMID:28422092
Descriptive Analysis of LAP1 Distribution and That of Associated Proteins throughout Spermatogenesis. PMID:28387711
Robust microbial cell segmentation by optical-phase thresholding with minimal processing requirements. PMID:28371011
DHX9 suppresses RNA processing defects originating from the Alu invasion of the human genome. PMID:28355180
Loss of the RNA helicase SKIV2L2 impairs mitotic progression and replication-dependent histone mRNA turnover in murine cell lines. PMID:28351885
Pan-cancer analysis distinguishes transcriptional changes of aneuploidy from proliferation. PMID:28320919
A method for characterizing phenotypic changes in highly variable cell populations and its application to high content screening of Arabidopsis thaliana protoplasts. PMID:28245335
Large-Scale Analysis of CRISPR/Cas9 Cell-Cycle Knockouts Reveals the Diversity of p53-Dependent Responses to Cell-Cycle Defects. PMID:28216383
How can functional annotations be derived from profiles of phenotypic annotations? PMID:28183267
Mitotic cell death induction by targeting the mitotic spindle with tubulin-inhibitory indole derivative molecules. PMID:28160569
Accurate Detection of Dysmorphic Nuclei Using Dynamic Programming and Supervised Classification. PMID:28125723
Quantitative microscopy uncovers ploidy changes during mitosis in live Drosophila embryos and their effect on nuclear size. PMID:28108477
Pleckstrin homology domain-containing protein PHLDB3 supports cancer growth via a negative feedback loop involving p53. PMID:28008906
Perturb-Seq: Dissecting Molecular Circuits with Scalable Single-Cell RNA Profiling of Pooled Genetic Screens. PMID:27984732
Profiling DNA damage response following mitotic perturbations. PMID:27976684
Machine learning and computer vision approaches for phenotypic profiling. PMID:27940887
Genome-wide screen of cell-cycle regulators in normal and tumor cells identifies a differential response to nucleosome depletion. PMID:27929715
Imagining the future of bioimage analysis. PMID:27926723
Spliceosomal protein eftud2 mutation leads to p53-dependent apoptosis in zebrafish neural progenitors. PMID:27899647
Characterization and Genetic Analyses of New Genes Coding for NOD2 Interacting Proteins. PMID:27812135
Dissecting Torsin/cofactor function at the nuclear envelope: a genetic study. PMID:27798237
Condensin II mutation causes T-cell lymphoma through tissue-specific genome instability. PMID:27737961
A genome-wide screen to identify genes controlling the rate of entry into mitosis in fission yeast. PMID:27736299
XAB2 functions in mitotic cell cycle progression via transcriptional regulation of CENPE. PMID:27735937
The poly(ADP-ribose)-dependent chromatin remodeler Alc1 induces local chromatin relaxation upon DNA damage. PMID:27733626
Single cell dynamic phenotyping. PMID:27708391
SUMOylated NKAP is essential for chromosome alignment by anchoring CENP-E to kinetochores. PMID:27694884
A bead-based western for high-throughput cellular signal transduction analyses. PMID:27659302
Nuclear pore assembly proceeds by an inside-out extrusion of the nuclear envelope. PMID:27630123
πSPIM: high NA high resolution isotropic light-sheet imaging in cell culture dishes. PMID:27619647
Expanding the Diversity of Imaging-Based RNAi Screen Applications Using Cell Spot Microarrays. PMID:27605183
Living Cell Microarrays: An Overview of Concepts. PMID:27600077
Targeting protein function: the expanding toolkit for conditional disruption. PMID:27574023
ASPM and CITK regulate spindle orientation by affecting the dynamics of astral microtubules. PMID:27562601
Accurate Morphology Preserving Segmentation of Overlapping Cells based on Active Contours. PMID:27561654
The RNA-binding protein ATX-2 regulates cytokinesis through PAR-5 and ZEN-4. PMID:27559134
Responses of chromosome segregation machinery to mechanical perturbations. PMID:27493543
Mitotic noncoding RNA processing promotes kinetochore and spindle assembly in Xenopus. PMID:27402954
A high-resolution transcriptome map of cell cycle reveals novel connections between periodic genes and cancer. PMID:27364684
Ki-67 acts as a biological surfactant to disperse mitotic chromosomes. PMID:27362226
Through the Looking Glass: Time-lapse Microscopy and Longitudinal Tracking of Single Cells to Study Anti-cancer Therapeutics. PMID:27213923
The cellular microscopy phenotype ontology. PMID:27195102
Mechanisms of Mitotic Spindle Assembly. PMID:27145846
Identification of Candidate Cyclin-dependent kinase 1 (Cdk1) Substrates in Mitosis by Quantitative Phosphoproteomics. PMID:27134283
Image-based computational quantification and visualization of genetic alterations and tumour heterogeneity. PMID:27052161
A versatile multivariate image analysis pipeline reveals features of Xenopus extract spindles. PMID:27044897
MicroRNA-122 regulates polyploidization in the murine liver. PMID:27016325
Principles of dynamical modularity in biological regulatory networks. PMID:26979940
ARHGEF17 sets the timer for retention of Mps1 at kinetochores. PMID:26953355
ARHGEF17 is an essential spindle assembly checkpoint factor that targets Mps1 to kinetochores. PMID:26953350
Small RAB GTPases Regulate Multiple Steps of Mitosis. PMID:26925400
IK-guided PP2A suppresses Aurora B activity in the interphase of tumor cells. PMID:26906715
Rab8 directs furrow ingression and membrane addition during epithelial formation in Drosophila melanogaster. PMID:26839362
An analysis toolbox to explore mesenchymal migration heterogeneity reveals adaptive switching between distinct modes. PMID:26821527
Compact Wireless Microscope for In-Situ Time Course Study of Large Scale Cell Dynamics within an Incubator. PMID:26681552
Mineotaur: a tool for high-content microscopy screen sharing and visual analytics. PMID:26679168
High-throughput single-molecule screen for small-molecule perturbation of splicing and transcription kinetics. PMID:26655523
Torsins: not your typical AAA+ ATPases. PMID:26592310
A novel role for atypical MAPK kinase ERK3 in regulating breast cancer cell morphology and migration. PMID:26588708
The pathogenicity of splicing defects: mechanistic insights into pre-mRNA processing inform novel therapeutic approaches. PMID:26566663
Single-cell phenomics in budding yeast. PMID:26543200
CellProfiler Tracer: exploring and validating high-throughput, time-lapse microscopy image data. PMID:26537300
The γ-tubulin-specific inhibitor gatastatin reveals temporal requirements of microtubule nucleation during the cell cycle. PMID:26503935
Building cell models and simulations from microscope images. PMID:26484733
Targeting mitochondrial RNA polymerase in acute myeloid leukemia. PMID:26484416
Metadata management for high content screening in OMERO. PMID:26476368
Using ToxCast™ Data to Reconstruct Dynamic Cell State Trajectories and Estimate Toxicological Points of Departure. PMID:26473631
Ubiquitin systems mark pathogen-containing vacuoles as targets for host defense by guanylate binding proteins. PMID:26417105
Guanylate binding proteins enable rapid activation of canonical and noncanonical inflammasomes in Chlamydia-infected macrophages. PMID:26416908
Regulation of constitutive and alternative mRNA splicing across the human transcriptome by PRPF8 is determined by 5' splice site strength. PMID:26392272
Prediction of Functionally Important Phospho-Regulatory Events in Xenopus laevis Oocytes. PMID:26312481
An epigenetic regulator emerges as microtubule minus-end binding and stabilizing factor in mitosis. PMID:26243146
Identification of anti-tumour biologics using primary tumour models, 3-D phenotypic screening and image-based multi-parametric profiling. PMID:26227951
Publishing and sharing multi-dimensional image data with OMERO. PMID:26223880
An siRNA-based functional genomics screen for the identification of regulators of ciliogenesis and ciliopathy genes. PMID:26167768
Loading of PAX3 to Mitotic Chromosomes Is Mediated by Arginine Methylation and Associated with Waardenburg Syndrome. PMID:26149688
Cezanne regulates E2F1-dependent HIF2α expression. PMID:26148512
A generic methodological framework for studying single cell motility in high-throughput time-lapse data. PMID:26072499
Live imaging and modeling of inner nuclear membrane targeting reveals its molecular requirements in mammalian cells. PMID:26056140
A sensitised RNAi screen reveals a ch-TOG genetic interaction network required for spindle assembly. PMID:26037491
Transcriptional control of mitosis: deregulation and cancer. PMID:25999914
Application guide for omics approaches to cell signaling. PMID:25978996
Building the Microtubule Cytoskeleton Piece by Piece. PMID:25957410
CMTX1 patients' cells present genomic instability corrected by CamKII inhibitors. PMID:25947624
MXS-Chaining: A Highly Efficient Cloning Platform for Imaging and Flow Cytometry Approaches in Mammalian Systems. PMID:25909630
Shade avoidance components and pathways in adult plants revealed by phenotypic profiling. PMID:25874869
Cellular phenotype database: a repository for systems microscopy data. PMID:25861964
Cell-based screening: extracting meaning from complex data. PMID:25856492
Electroporation Knows No Boundaries: The Use of Electrostimulation for siRNA Delivery in Cells and Tissues. PMID:25851034
Centriolar satellite- and hMsd1/SSX2IP-dependent microtubule anchoring is critical for centriole assembly. PMID:25833712
Large-scale chemical similarity networks for target profiling of compounds identified in cell-based chemical screens. PMID:25826798
Zinc finger independent genome-wide binding of Sp2 potentiates recruitment of histone-fold protein Nf-y distinguishing it from Sp1 and Sp3. PMID:25793500
RHAMM deficiency disrupts folliculogenesis resulting in female hypofertility. PMID:25750434
Modulation of phosphatidylinositol 4-phosphate levels by CaBP7 controls cytokinesis in mammalian cells. PMID:25717182
Two-pore channel 1 interacts with citron kinase, regulating completion of cytokinesis. PMID:25665131
Loss of citron kinase affects a subset of progenitor cells that alters late but not early neurogenesis in the developing rat retina. PMID:25593024
Poisson-event-based analysis of cell proliferation. PMID:25572722
Visualizing cellular imaging data using PhenoPlot. PMID:25569359
A microfluidic platform for correlative live-cell and super-resolution microscopy. PMID:25545548
Structure of an APC3-APC16 complex: insights into assembly of the anaphase-promoting complex/cyclosome. PMID:25490258
Physical basis of spindle self-organization. PMID:25468965
Inhibition of SNW1 association with spliceosomal proteins promotes apoptosis in breast cancer cells. PMID:25450007
Single-cell and multivariate approaches in genetic perturbation screens. PMID:25446316
Host cell factor-1 recruitment to E2F-bound and cell-cycle-control genes is mediated by THAP11 and ZNF143. PMID:25437553
The BioGRID interaction database: 2015 update. PMID:25428363
Global linking of cell tracks using the Viterbi algorithm. PMID:25415983
The catalytically inactive tyrosine phosphatase HD-PTP/PTPN23 is a novel regulator of SMN complex localization. PMID:25392300
Cyclebase 3.0: a multi-organism database on cell-cycle regulation and phenotypes. PMID:25378319
The kinetochore protein Kis1/Eic1/Mis19 ensures the integrity of mitotic spindles through maintenance of kinetochore factors Mis6/CENP-I and CENP-A. PMID:25375240
A genomic Multiprocess survey of machineries that control and link cell shape, microtubule organization, and cell-cycle progression. PMID:25373780
LAP1 is a crucial protein for the maintenance of the nuclear envelope structure and cell cycle progression. PMID:25323962
Chemical dissection of the cell cycle: probes for cell biology and anti-cancer drug development. PMID:25321469
Splicing together sister chromatids. PMID:25266476
Functional genomics identifies a requirement of pre-mRNA splicing factors for sister chromatid cohesion. PMID:25257310
SNW1 enables sister chromatid cohesion by mediating the splicing of sororin and APC2 pre-mRNAs. PMID:25257309
Characterizing protein interactions employing a genome-wide siRNA cellular phenotyping screen. PMID:25255318
Deregulation of the replisome factor MCMBP prompts oncogenesis in colorectal carcinomas through chromosomal instability. PMID:25246271
Comparative assessment of fluorescent transgene methods for quantitative imaging in human cells. PMID:25232003
Systems and synthetic biology approaches to cell division. PMID:25136378
UBL5 is essential for pre-mRNA splicing and sister chromatid cohesion in human cells. PMID:25092792
Sororin pre-mRNA splicing is required for proper sister chromatid cohesion in human cells. PMID:25092791
Pericentriolar material structure and dynamics. PMID:25047613
Deep Imaging: the next frontier in microscopy. PMID:24989801
Integration of biological data by kernels on graph nodes allows prediction of new genes involved in mitotic chromosome condensation. PMID:24943848
A new role for Rab GTPases during early mitotic stages. PMID:24921241
Spatial regulation of Aurora A activity during mitotic spindle assembly requires RHAMM to correctly localize TPX2. PMID:24875404
The conserved ubiquitin-like protein Hub1 plays a critical role in splicing in human cells. PMID:24872507
The translational landscape of the splicing factor SRSF1 and its role in mitosis. PMID:24842991
Association of condensin with chromosomes depends on DNA binding by its HEAT-repeat subunits. PMID:24837193
Automated identification of subcellular organelles by coherent anti-stokes Raman scattering. PMID:24806923
Modulation of the chromatin phosphoproteome by the Haspin protein kinase. PMID:24732914
What's that gene (or protein)? Online resources for exploring functions of genes, transcripts, and proteins. PMID:24723265
Increasing the Content of High-Content Screening: An Overview. PMID:24710339
Role of receptor for hyaluronan-mediated motility (RHAMM) in human head and neck cancers. PMID:24676428
A versatile assay for RNA-binding proteins in living cells. PMID:24664470
Integrated and correlative high-throughput and super-resolution microscopy. PMID:24647616
Noise genetics: inferring protein function by correlating phenotype with protein levels and localization in individual human cells. PMID:24603725
Exploiting cell-to-cell variability to detect cellular perturbations. PMID:24594940
cellXpress: a fast and user-friendly software platform for profiling cellular phenotypes. PMID:24564609
Deducing the mechanism of action of compounds identified in phenotypic screens by integrating their multiparametric profiles with a reference genetic screen. PMID:24481274
Stable RNA interference rules for silencing. PMID:24366030
Deducing protein function by forensic integrative cell biology. PMID:24358025
STRIPAK complexes: structure, biological function, and involvement in human diseases. PMID:24333164
The centrosomal adaptor TACC3 and the microtubule polymerase chTOG interact via defined C-terminal subdomains in an Aurora-A kinase-independent manner. PMID:24273164
Small GTPases as regulators of cell division. PMID:24265858
A novel phenotypic dissimilarity method for image-based high-throughput screens. PMID:24256072
Genes involved in centrosome-independent mitotic spindle assembly in Drosophila S2 cells. PMID:24255106
Tissue specificity in the nuclear envelope supports its functional complexity. PMID:24213376
The vertebrate-specific Kinesin-6, Kif20b, is required for normal cytokinesis of polarized cortical stem cells and cerebral cortex size. PMID:24173802
Dynamical modelling of phenotypes in a genome-wide RNAi live-cell imaging assay. PMID:24131777
Evaluation of the effectiveness of simple nuclei-segmentation methods on Caenorhabditis elegans embryogenesis images. PMID:24090283
Unsupervised automated high throughput phenotyping of RNAi time-lapse movies. PMID:24090185
The Prp19 complex directly functions in mitotic spindle assembly. PMID:24069358
The cytoskeletal protein RHAMM and ERK1/2 activity maintain the pluripotency of murine embryonic stem cells. PMID:24019927
A chemostat array enables the spatio-temporal analysis of the yeast proteome. PMID:24019481
Genome-wide RNAi high-throughput screen identifies proteins necessary for the AHR-dependent induction of CYP1A1 by 2,3,7,8-tetrachlorodibenzo-p-dioxin. PMID:23997114
PhenoTimer: software for the visual mapping of time-resolved phenotypic landscapes. PMID:23951317
NuMA phosphorylation by CDK1 couples mitotic progression with cortical dynein function. PMID:23921553
A systematic analysis of the PARP protein family identifies new functions critical for cell physiology. PMID:23917125
REEP3/4 ensure endoplasmic reticulum clearance from metaphase chromatin and proper nuclear envelope architecture. PMID:23911198
Systematic quantification of developmental phenotypes at single-cell resolution during embryogenesis. PMID:23861063
Zinc finger nuclease mediated knockout of ADP-dependent glucokinase in cancer cell lines: effects on cell survival and mitochondrial oxidative metabolism. PMID:23799003
Wide field-of-view Talbot grid-based microscopy for multicolor fluorescence imaging. PMID:23787643
A genome-wide resource of cell cycle and cell shape genes of fission yeast. PMID:23697806
A simple high-content cell cycle assay reveals frequent discrepancies between cell number and ATP and MTS proliferation assays. PMID:23691072
LIPS database with LIPService: a microscopic image database of intracellular structures in Arabidopsis guard cells. PMID:23679342
Notch2 regulates BMP signaling and epithelial morphogenesis in the ciliary body of the mouse eye. PMID:23676271
EGF-induced centrosome separation promotes mitotic progression and cell survival. PMID:23643362
Chapter 17: bioimage informatics for systems pharmacology. PMID:23633943
Light microscopy applications in systems biology: opportunities and challenges. PMID:23578051
The genomic and transcriptomic landscape of a HeLa cell line. PMID:23550136
RNAi-based functional profiling of loci from blood lipid genome-wide association studies identifies genes with cholesterol-regulatory function. PMID:23468663
CEP proteins: the knights of centrosome dynasty. PMID:23456457
Profiling of ubiquitin-like modifications reveals features of mitotic control. PMID:23452859
Visualization of protein interaction networks: problems and solutions. PMID:23368786
A kinetic model for RNA-interference of focal adhesions. PMID:23311633
miR-17-5p regulates endocytic trafficking through targeting TBC1D2/Armus. PMID:23285084
The study of muscle remodeling in Drosophila metamorphosis using in vivo microscopy and bioimage informatics. PMID:23282138
Quantitative analysis of chromosome condensation in fission yeast. PMID:23263988
Tubulin tyrosine ligase like 12, a TTLL family member with SET- and TTL-like domains and roles in histone and tubulin modifications and mitosis. PMID:23251473
Evolutionarily conserved protein ERH controls CENP-E mRNA splicing and is required for the survival of KRAS mutant cancer cells. PMID:23236152
Omcg1 is critically required for mitosis in rapidly dividing mouse intestinal progenitors and embryonic stem cells. PMID:23213458
Nucleotide composition of cellular internal ribosome entry sites defines dependence on NF45 and predicts a posttranscriptional mitotic regulon. PMID:23129811
miR-125b promotes cell death by targeting spindle assembly checkpoint gene MAD1 and modulating mitotic progression. PMID:23099851
R26R-GR: a Cre-activable dual fluorescent protein reporter mouse. PMID:23049968
Targeting protein for xenopus kinesin-like protein 2 (TPX2) regulates γ-histone 2AX (γ-H2AX) levels upon ionizing radiation. PMID:23045526
Cortical dynein is critical for proper spindle positioning in human cells. PMID:23027904
Shedding light on filovirus infection with high-content imaging. PMID:23012631
Charting the landscape of tandem BRCT domain-mediated protein interactions. PMID:22990118
Mitotic lamin disassembly is triggered by lipid-mediated signaling. PMID:22986494
A transcription factor-based mechanism for mouse heterochromatin formation. PMID:22983563
Visualizing global effects of the DNA damage response. PMID:22945255
A census of human soluble protein complexes. PMID:22939629
Active learning framework with iterative clustering for bioimage classification. PMID:22929789
A probabilistic model for cell population phenotyping using HCS data. PMID:22927936
Mapping the human phosphatome on growth pathways. PMID:22893001
G protein-coupled receptors participate in cytokinesis. PMID:22888021
Functional genomic and high-content screening for target discovery and deconvolution. PMID:22860749
New insights into subcomplex assembly and modifications of centrosomal proteins. PMID:22800182
Isolation of human mitotic protein phosphatase complexes: identification of a complex between protein phosphatase 1 and the RNA helicase Ddx21. PMID:22761809
BioImageXD: an open, general-purpose and high-throughput image-processing platform. PMID:22743773
Fiji: an open-source platform for biological-image analysis. PMID:22743772
Deformations within moving kinetochores reveal different sites of active and passive force generation. PMID:22722252
Computational analysis of high-throughput flow cytometry data. PMID:22708834
A novel function of Rab5 in mitosis. PMID:22694819
Genome-wide localization and expression profiling establish Sp2 as a sequence-specific transcription factor regulating vitally important genes. PMID:22684502
Functional repurposing revealed by comparing S. pombe and S. cerevisiae genetic interactions. PMID:22682253
Genome-wide RNAi screening identifies human proteins with a regulatory function in the early secretory pathway. PMID:22660414
Development of cysteine-free fluorescent proteins for the oxidative environment. PMID:22649538
Unsupervised modeling of cell morphology dynamics for time-lapse microscopy. PMID:22635062
MicroSCALE screening reveals genetic modifiers of therapeutic response in melanoma. PMID:22589389
Evolutionary conservation and network structure characterize genes of phenotypic relevance for mitosis in human. PMID:22577488
Shaping the nucleus: factors and forces. PMID:22566057
Semantic integration of physiology phenotypes with an application to the Cellular Phenotype Ontology. PMID:22539675
Single-cell analysis of population context advances RNAi screening at multiple levels. PMID:22531119
Arena3D: visualizing time-driven phenotypic differences in biological systems. PMID:22439608
How to link ontologies and protein-protein interactions to literature: text-mining approaches and the BioCreative experience. PMID:22438567
Uncovering the molecular machinery of the human spindle--an integration of wet and dry systems biology. PMID:22427808
Sm protein down-regulation leads to defects in nuclear pore complex disassembly and distribution in C. elegans embryos. PMID:22426005
Innovation in biological microscopy: current status and future directions. PMID:22408015
CC2D1A is a regulator of ESCRT-III CHMP4B. PMID:22406677
Cell cycle phase classification in 3D in vivo microscopy of Drosophila embryogenesis. PMID:22372955
Emerging regulatory mechanisms in ubiquitin-dependent cell cycle control. PMID:22357967
Development of novel mouse hybridomas producing monoclonal antibodies specific to human and mouse nucleolar protein SURF-6. PMID:22316485
Germline mutations in DIS3L2 cause the Perlman syndrome of overgrowth and Wilms tumor susceptibility. PMID:22306653
p27(Kip1) controls cytokinesis via the regulation of citron kinase activation. PMID:22293177
Microwell perfusion array for high-throughput, long-term imaging of clonal growth. PMID:22259644
G Protein-coupled receptor kinase 5 is localized to centrosomes and regulates cell cycle progression. PMID:22223642
Expression and role in glycolysis of human ADP-dependent glucokinase. PMID:22219026
Mutability and mutational spectrum of chromosome transmission fidelity genes. PMID:22198145
Normalizing for individual cell population context in the analysis of high-content cellular screens. PMID:22185194
Molecular basis for the association of microcephalin (MCPH1) protein with the cell division cycle protein 27 (Cdc27) subunit of the anaphase-promoting complex. PMID:22139841
A framework for image-based classification of mitotic cells in asynchronous populations. PMID:22084958
Nucleoporin NUP153 guards genome integrity by promoting nuclear import of 53BP1. PMID:22075984
The quantitative proteome of a human cell line. PMID:22068332
Systematic phosphorylation analysis of human mitotic protein complexes. PMID:22067460
Decidual cell polyploidization necessitates mitochondrial activity. PMID:22046353
K11-linked ubiquitin chains as novel regulators of cell division. PMID:21978762
TPX2 regulates the localization and activity of Eg5 in the mammalian mitotic spindle. PMID:21969468
Genomic analysis at the single-cell level. PMID:21942365
A Potential of microRNAs for High-Content Screening. PMID:21922044
Post-translational membrane insertion of tail-anchored transmembrane EF-hand Ca2+ sensor calneurons requires the TRC40/Asna1 protein chaperone. PMID:21878631
Formation of stable attachments between kinetochores and microtubules depends on the B56-PP2A phosphatase. PMID:21874008
Citron kinase controls abscission through RhoA and anillin. PMID:21849473
Extracting quantitative genetic interaction phenotypes from matrix combinatorial RNAi. PMID:21849035
Differential inhibitor sensitivity between human kinases VRK1 and VRK2. PMID:21829721
Live-cell microscopy reveals small molecule inhibitor effects on MAPK pathway dynamics. PMID:21829637
Automated microscopy and image analysis for androgen receptor function. PMID:21796534
Phenotypic profiling of the human genome reveals gene products involved in plasma membrane targeting of SRC kinases. PMID:21795383
Probing the in vivo function of Mad1:C-Mad2 in the spindle assembly checkpoint. PMID:21772247
Time-resolved human kinome RNAi screen identifies a network regulating mitotic-events as early regulators of cell proliferation. PMID:21765947
Insights into the micromechanical properties of the metaphase spindle. PMID:21703450
A high-throughput platform for lentiviral overexpression screening of the human ORFeome. PMID:21629697
Discovering the targets of drugs via computational systems biology. PMID:21566122
Mitotic moonlighting functions for membrane trafficking proteins. PMID:21564450
A protein network-guided screen for cell cycle regulators in Drosophila. PMID:21548953
A high-resolution C. elegans essential gene network based on phenotypic profiling of a complex tissue. PMID:21529718
Chromatin in the nuclear landscape. PMID:21502408
Stress-induced expression of p53 target genes is insensitive to SNW1/SKIP downregulation. PMID:21461980
How to be a mitotic chromosome. PMID:21461697
High-throughput phenotyping of multicellular organisms: finding the link between genotype and phenotype. PMID:21457493
Spindle assembly checkpoint protein Cdc20 transcriptionally activates expression of ubiquitin carrier protein UbcH10. PMID:21454660
A cell spot microarray method for production of high density siRNA transfection microarrays. PMID:21443765
Novel asymmetrically localizing components of human centrosomes identified by complementary proteomics methods. PMID:21399614
Myosin light chain kinases and phosphatase in mitosis and cytokinesis. PMID:21396909
Downregulation of VRK1 by p53 in response to DNA damage is mediated by the autophagic pathway. PMID:21386980
Cell death assays for drug discovery. PMID:21358741
The function of spliceosome components in open mitosis. PMID:21327086
The living microarray: a high-throughput platform for measuring transcription dynamics in single cells. PMID:21324195
53BP1 nuclear bodies form around DNA lesions generated by mitotic transmission of chromosomes under replication stress. PMID:21317883
Centriolar satellites are assembly points for proteins implicated in human ciliopathies, including oral-facial-digital syndrome 1. PMID:21266464
Micropilot: automation of fluorescence microscopy-based imaging for systems biology. PMID:21258339
Origins of regulated cell-to-cell variability. PMID:21224886
Systems biology in immunology: a computational modeling perspective. PMID:21219182
Where gene discovery turns into systems biology: genome-scale RNAi screens in Drosophila. PMID:21197652
The Plant Organelles Database 2 (PODB2): an updated resource containing movie data of plant organelle dynamics. PMID:21115470
A hybrid blob-slice model for accurate and efficient detection of fluorescence labeled nuclei in 3D. PMID:21114815
CENP-A, a protein required for chromosome segregation in mitosis, declines with age in islet but not exocrine cells. PMID:21068465
Human ASPM participates in spindle organisation, spindle orientation and cytokinesis. PMID:21044324
Building mitotic chromosomes. PMID:20974528
Timing is everything in the human embryo. PMID:20944588
High-throughput, single-cell NF-κB dynamics. PMID:20846851
Symplekin specifies mitotic fidelity by supporting microtubule dynamics. PMID:20823274
The protein composition of mitotic chromosomes determined using multiclassifier combinatorial proteomics. PMID:20813266
The Fanconi anemia pathway and ICL repair: implications for cancer therapy. PMID:20807115
Live-cell imaging RNAi screen identifies PP2A-B55alpha and importin-beta1 as key mitotic exit regulators in human cells. PMID:20711181
CellCognition: time-resolved phenotype annotation in high-throughput live cell imaging. PMID:20693996
Descriptive no more: the dawn of high-throughput microscopy. PMID:20667736
Systems microscopy approaches to understand cancer cell migration and metastasis. PMID:20556632
Discovering Mozart. PMID:20521367
Metadata matters: access to image data in the real world. PMID:20513764
High-content imaging. PMID:20458305
A molecular mechanism underlying the neural-specific defect in torsinA mutant mice. PMID:20457914
Prophase I arrest and progression to metaphase I in mouse oocytes: comparison of resumption of meiosis and recovery from G2-arrest in somatic cells. PMID:20453035
Cell cycle: dissecting mitosis. PMID:20419887
Cell biology forum: Genome-wide view of mitosis. PMID:20360724
Automated microscopy for high-content RNAi screening. PMID:20176920 -
Systematic analysis of human protein complexes identifies chromosome segregation proteins
PubMed citations: 287.
287 articles citing: Systematic analysis of human protein complexes identifies chromosome segregation proteins
Reconstitution and mechanistic dissection of the human microtubule branching machinery. PMID:35604367
Ki67 for evaluating the prognosis of gastrointestinal stromal tumors: A systematic review and meta-analysis. PMID:35527778
RBPMS is an RNA-binding protein that mediates cardiomyocyte binucleation and cardiovascular development. PMID:35472321
OpenCell: Endogenous tagging for the cartography of human cellular organization. PMID:35271311
The Dictyostelium Centrosome. PMID:34685637
Assembly defects of human tRNA splicing endonuclease contribute to impaired pre-tRNA processing in pontocerebellar hypoplasia. PMID:34584079
Interactome Analysis of KIN (Kin17) Shows New Functions of This Protein. PMID:34449532
Troy/Tnfrsf19 marks epidermal cells that govern interfollicular epidermal renewal and cornification. PMID:34358453
Condensation of pericentrin proteins in human cells illuminates phase separation in centrosome assembly. PMID:34308971
Molecular insight into how γ-TuRC makes microtubules. PMID:34297125
Application of PALM Superresolution Microscopy to the Analysis of Microtubule-Organizing Centers (MTOCs) in Aspergillus nidulans. PMID:34085230
Autoinhibition of Cnn binding to γ-TuRCs prevents ectopic microtubule nucleation and cell division defects. PMID:34042945
Accelerated Evolution of Tissue-Specific Genes Mediates Divergence Amidst Gene Flow in European Green Lizards. PMID:33988711
MZT2A promotes NSCLC viability and invasion by increasing Akt phosphorylation via the MOZART2 domain. PMID:33754417
Dual Inhibition of γ-Tubulin and Plk1 Induces Mitotic Cell Death. PMID:33584305
Biochemical reconstitutions reveal principles of human γ-TuRC assembly and function. PMID:33496729
Ecd promotes U5 snRNP maturation and Prp8 stability. PMID:33444449
Current and Potential Applications of Artificial Intelligence in Gastrointestinal Stromal Tumor Imaging. PMID:33304203
ESI mutagenesis: a one-step method for introducing mutations into bacterial artificial chromosomes. PMID:33293335
Serpin peptidase inhibitor clade A member 1-overexpression in gastric cancer promotes tumor progression in vitro and is associated with poor prognosis. PMID:33014156
Protein interactome mapping in Caenorhabditis elegans. PMID:32984658
Ordered dephosphorylation initiated by the selective proteolysis of cyclin B drives mitotic exit. PMID:32869743
Exome sequencing links CEP120 mutation to maternally derived aneuploid conception risk. PMID:32772081
MZT Proteins Form Multi-Faceted Structural Modules in the γ-Tubulin Ring Complex. PMID:32610146
Novel loss-of-function mutation in HERC2 is associated with severe developmental delay and paediatric lethality. PMID:32571899
Microtubule Nucleation Properties of Single Human γTuRCs Explained by Their Cryo-EM Structure. PMID:32433913
CRISPR-mediated gene targeting of CK1δ/ε leads to enhanced understanding of their role in endocytosis via phosphoregulation of GAPVD1. PMID:32321936
Microneedle manipulation of the mammalian spindle reveals specialized, short-lived reinforcement near chromosomes. PMID:32191206
Overexpression of SAPCD2 correlates with proliferation and invasion of colorectal carcinoma cells. PMID:32055236
Personalized CT-based radiomics nomogram preoperative predicting Ki-67 expression in gastrointestinal stromal tumors: a multicenter development and validation cohort. PMID:32006200
Asymmetric Molecular Architecture of the Human γ-Tubulin Ring Complex. PMID:31862189
Aldh1b1 expression defines progenitor cells in the adult pancreas and is required for Kras-induced pancreatic cancer. PMID:31548432
A novel assay to screen siRNA libraries identifies protein kinases required for chromosome transmission. PMID:31515286
The Tousled-like kinases regulate genome and epigenome stability: implications in development and disease. PMID:31302748
The Centrosome and the Primary Cilium: The Yin and Yang of a Hybrid Organelle. PMID:31295970
Reconstitution of Microtubule Nucleation In Vitro Reveals Novel Roles for Mzt1. PMID:31287970
Systematic identification of recognition motifs for the hub protein LC8. PMID:31266884
Live imaging screen reveals that TYRO3 and GAK ensure accurate spindle positioning in human cells. PMID:31253758
How to use a multipurpose SNARE: The emerging role of Snap29 in cellular health. PMID:31225470
Dissecting the mechanisms of cell division. PMID:31175154
High Expression of Human AugminComplex Submit 3 Indicates Poor Prognosis and Associates with Tumor Progression in Hepatocellular Carcinoma. PMID:31031853
The interaction networks of the budding yeast and human DNA replication-initiation proteins. PMID:30890025
Detecting Chromosome Instability in Cancer: Approaches to Resolve Cell-to-Cell Heterogeneity. PMID:30781398
Concerted expression of a cell cycle regulator and a metabolic enzyme from a bicistronic transcript in plants. PMID:30737513
Profiling proliferative cells and their progeny in damaged murine hearts. PMID:30530645
Roles of end-binding 1 protein and gamma-tubulin small complex in cytokinesis and flagella formation of Giardia lamblia. PMID:30318753
Microtubule nucleation by γ-tubulin complexes and beyond. PMID:30315097
Dynamic regulation of dynein localization revealed by small molecule inhibitors of ubiquitination enzymes. PMID:30257893
Integrin and microtubule crosstalk in the regulation of cellular processes. PMID:30206641
SHLD2/FAM35A co-operates with REV7 to coordinate DNA double-strand break repair pathway choice. PMID:30154076
Conditional control of fluorescent protein degradation by an auxin-dependent nanobody. PMID:30120238
The Spindle: Integrating Architecture and Mechanics across Scales. PMID:30093097
Tissue-specific degradation of essential centrosome components reveals distinct microtubule populations at microtubule organizing centers. PMID:30080857
The shieldin complex mediates 53BP1-dependent DNA repair. PMID:30022168
γ-TuRC Heterogeneity Revealed by Analysis of Mozart1. PMID:29983314
The replicative helicase MCM recruits cohesin acetyltransferase ESCO2 to mediate centromeric sister chromatid cohesion. PMID:29930102
NEK7 regulates dendrite morphogenesis in neurons via Eg5-dependent microtubule stabilization. PMID:29899413
RegenDbase: a comparative database of noncoding RNA regulation of tissue regeneration circuits across multiple taxa. PMID:29872545
Mitotic-Spindle Organizing Protein MztA Mediates Septation Signaling by Suppressing the Regulatory Subunit of Protein Phosphatase 2A-ParA in Aspergillus nidulans. PMID:29774021
PPI network analyses of human WD40 protein family systematically reveal their tendency to assemble complexes and facilitate the complex predictions. PMID:29745845
The kinase domain of CK1 enzymes contains the localization cue essential for compartmentalized signaling at the spindle pole. PMID:29742018
Degradation of a Novel DNA Damage Response Protein, Tankyrase 1 Binding Protein 1, following Adenovirus Infection. PMID:29593045
Aberrant GlyRS-HDAC6 interaction linked to axonal transport deficits in Charcot-Marie-Tooth neuropathy. PMID:29520015
Assembly and regulation of γ-tubulin complexes. PMID:29514869
HDAC6 is a therapeutic target in mutant GARS-induced Charcot-Marie-Tooth disease. PMID:29415205
Development of a yeast internal-subunit eGFP labeling strategy and its application in subunit identification in eukaryotic group II chaperonin TRiC/CCT. PMID:29403048
Troy+ brain stem cells cycle through quiescence and regulate their number by sensing niche occupancy. PMID:29311336
A High-Resolution Proteomic Landscaping of Primary Human Dental Stem Cells: Identification of SHED- and PDLSC-Specific Biomarkers. PMID:29304003
The nuclear matrix protein HNRNPU maintains 3D genome architecture globally in mouse hepatocytes. PMID:29273625
Microtubins: a novel class of small synthetic microtubule targeting drugs that inhibit cancer cell proliferation. PMID:29262617
Phase Transitioning the Centrosome into a Microtubule Nucleator. PMID:29256606
Visualizing the complex functions and mechanisms of the anaphase promoting complex/cyclosome (APC/C). PMID:29167309
EB1-binding-myomegalin protein complex promotes centrosomal microtubules functions. PMID:29162697
Genome-scale single-cell mechanical phenotyping reveals disease-related genes involved in mitotic rounding. PMID:29097687
HMMR acts in the PLK1-dependent spindle positioning pathway and supports neural development. PMID:28994651
An Endogenously Tagged Fluorescent Fusion Protein Library in Mouse Embryonic Stem Cells. PMID:28966122
ZATT (ZNF451)-mediated resolution of topoisomerase 2 DNA-protein cross-links. PMID:28912134
Nucleolar and spindle-associated protein 1 (NUSAP1) interacts with a SUMO E3 ligase complex during chromosome segregation. PMID:28900032
Differential DNA methylation at birth associated with mental disorder in individuals with 22q11.2 deletion syndrome. PMID:28850114
Ki67 is a biological marker of malignant risk of gastrointestinal stromal tumors: A systematic review and meta-analysis. PMID:28834915
Nuclear envelope: a new frontier in plant mechanosensing? PMID:28801801
Quantitative Assessment of the Effects of Trypsin Digestion Methods on Affinity Purification-Mass Spectrometry-based Protein-Protein Interaction Analysis. PMID:28726418
A Splice Variant of Centrosomin Converts Mitochondria to Microtubule-Organizing Centers. PMID:28669756
R2TP/Prefoldin-like component RUVBL1/RUVBL2 directly interacts with ZNHIT2 to regulate assembly of U5 small nuclear ribonucleoprotein. PMID:28561026
Large-Scale Analysis of CRISPR/Cas9 Cell-Cycle Knockouts Reveals the Diversity of p53-Dependent Responses to Cell-Cycle Defects. PMID:28216383
Mitotic spindle assembly in animal cells: a fine balancing act. PMID:28174430
Mitotic Spindle Assembly in Land Plants: Molecules and Mechanisms. PMID:28125061
MGO3 and GIP1 act synergistically for the maintenance of centromeric cohesion. PMID:28033038
Interaction of p190A RhoGAP with eIF3A and Other Translation Preinitiation Factors Suggests a Role in Protein Biosynthesis. PMID:28007963
MOZART1 and γ-tubulin complex receptors are both required to turn γ-TuSC into an active microtubule nucleation template. PMID:27920216
While the revolution will not be crystallized, biochemistry reigns supreme. PMID:27673321
Decoding sORF translation - from small proteins to gene regulation. PMID:27653973
An essential step of kinetochore formation controlled by the SNARE protein Snap29. PMID:27647876
Expanding the Diversity of Imaging-Based RNAi Screen Applications Using Cell Spot Microarrays. PMID:27605183
Topoisomerase II beta interacts with cohesin and CTCF at topological domain borders. PMID:27582050
ASPM and CITK regulate spindle orientation by affecting the dynamics of astral microtubules. PMID:27562601
Quantitative analysis of human centrosome architecture by targeted proteomics and fluorescence imaging. PMID:27539480
Rheology of the Active Cell Cortex in Mitosis. PMID:27508442
Responses of chromosome segregation machinery to mechanical perturbations. PMID:27493543
Characterization of the NTPR and BD1 interacting domains of the human PICH-BEND3 complex. PMID:27487930
GPRC5A is a potential oncogene in pancreatic ductal adenocarcinoma cells that is upregulated by gemcitabine with help from HuR. PMID:27415424
Mitotic Checkpoint Regulators Control Insulin Signaling and Metabolic Homeostasis. PMID:27374329
Proteomics Analysis with a Nano Random Forest Approach Reveals Novel Functional Interactions Regulated by SMC Complexes on Mitotic Chromosomes. PMID:27231315
Recent advances in large-scale protein interactome mapping. PMID:27158474
Mechanisms of Mitotic Spindle Assembly. PMID:27145846
A Dynamical Framework for the All-or-None G1/S Transition. PMID:27136687
Prickle3 synergizes with Wtip to regulate basal body organization and cilia growth. PMID:27062996
A Homozygous Nme7 Mutation Is Associated with Situs Inversus Totalis. PMID:27060491
Synergistic role of fission yeast Alp16GCP6 and Mzt1MOZART1 in γ-tubulin complex recruitment to mitotic spindle pole bodies and spindle assembly. PMID:27053664
Conformation-specific anti-Mad2 monoclonal antibodies for the dissection of checkpoint signaling. PMID:26986935
A transducible nuclear/nucleolar protein, mLLP, regulates neuronal morphogenesis and synaptic transmission. PMID:26961175
Proteomic data on the nuclear interactome of human MCM9. PMID:26870752
Control of APC/C-dependent ubiquitin chain elongation by reversible phosphorylation. PMID:26811472
Lamina Associated Polypeptide 1 (LAP1) Interactome and Its Functional Features. PMID:26784240
Quantitative proteomics reveals novel protein interaction partners of PP2A catalytic subunit in pancreatic β-cells. PMID:26780722
Augmin shapes the anaphase spindle for efficient cytokinetic furrow ingression and abscission. PMID:26764096
The conserved Wdr8-hMsd1/SSX2IP complex localises to the centrosome and ensures proper spindle length and orientation. PMID:26545777
The γ-tubulin-specific inhibitor gatastatin reveals temporal requirements of microtubule nucleation during the cell cycle. PMID:26503935
Protein domain mapping by internal labeling and single particle electron microscopy. PMID:26431894
The Prediction and Validation of Small CDSs Expand the Gene Repertoire of the Smallest Known Eukaryotic Genomes. PMID:26421846
γ-Tubulin complexes in microtubule nucleation and beyond. PMID:26316498
Microtubule nucleation at the centrosome and beyond. PMID:26316453
An Association Rule Mining Approach to Discover lncRNAs Expression Patterns in Cancer Datasets. PMID:26273587
Building a ninefold symmetrical barrel: structural dissections of centriole assembly. PMID:26269428
Size Scaling of Microtubule Assemblies in Early Xenopus Embryos. PMID:26261283
γ-Tubulin complex in Trypanosoma brucei: molecular composition, subunit interdependence and requirement for axonemal central pair protein assembly. PMID:26224545
Loss of apoptosis-inducing factor critically affects MIA40 function. PMID:26158520
Arabidopsis MZT1 homologs GIP1 and GIP2 are essential for centromere architecture. PMID:26124146
Quantitative proteomic analysis shows differentially expressed HSPB1 in glioblastoma as a discriminating short from long survival factor and NOVA1 as a differentiation factor between low-grade astrocytoma and oligodendroglioma. PMID:26108672
Enhancer of Rudimentary Homolog Affects the Replication Stress Response through Regulation of RNA Processing. PMID:26100022
Distinct domains in Bub1 localize RZZ and BubR1 to kinetochores to regulate the checkpoint. PMID:26031201
Microtubules in plants. PMID:26019693
The Msd1-Wdr8-Pkl1 complex anchors microtubule minus ends to fission yeast spindle pole bodies. PMID:25987607
Building the Microtubule Cytoskeleton Piece by Piece. PMID:25957410
Transposon mutagenesis identifies genetic drivers of Braf(V600E) melanoma. PMID:25848750
Pharmacological manipulation of transcription factor protein-protein interactions: opportunities and obstacles. PMID:25848531
Tctex1d2 associates with short-rib polydactyly syndrome proteins and is required for ciliogenesis. PMID:25830415
EML4 promotes the loading of NUDC to the spindle for mitotic progression. PMID:25789526
High-throughput fluorescence correlation spectroscopy enables analysis of proteome dynamics in living cells. PMID:25774713
The emerging roles of GPRC5A in diseases. PMID:25621293
An improved toolbox to unravel the plant cellular machinery by tandem affinity purification of Arabidopsis protein complexes. PMID:25521792
Structure of an APC3-APC16 complex: insights into assembly of the anaphase-promoting complex/cyclosome. PMID:25490258
SHCBP1 is required for midbody organization and cytokinesis completion. PMID:25486361
Inhibition of SNW1 association with spliceosomal proteins promotes apoptosis in breast cancer cells. PMID:25450007
Shift in GATA3 functions, and GATA3 mutations, control progression and clinical presentation in breast cancer. PMID:25410484
Cyclebase 3.0: a multi-organism database on cell-cycle regulation and phenotypes. PMID:25378319
The kinetochore protein Kis1/Eic1/Mis19 ensures the integrity of mitotic spindles through maintenance of kinetochore factors Mis6/CENP-I and CENP-A. PMID:25375240
Moonlighting functions of the NRZ (mammalian Dsl1) complex. PMID:25364732
Chemical dissection of the cell cycle: probes for cell biology and anti-cancer drug development. PMID:25321469
Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes. PMID:25281560
SNW1 enables sister chromatid cohesion by mediating the splicing of sororin and APC2 pre-mRNAs. PMID:25257309
Silencing of STRN4 suppresses the malignant characteristics of cancer cells. PMID:25250919
UBL5 is essential for pre-mRNA splicing and sister chromatid cohesion in human cells. PMID:25092792
Mapping early fate determination in Lgr5+ crypt stem cells using a novel Ki67-RFP allele. PMID:25092767
The centrosome-Golgi apparatus nexus. PMID:25047616
Pericentriolar material structure and dynamics. PMID:25047613
Molecular architecture and mechanism of the anaphase-promoting complex. PMID:25043029
Increasing the precision of orthology-based complex prediction through network alignment. PMID:24918034
Coiled-coil proteins facilitated the functional expansion of the centrosome. PMID:24901223
Nucleosome positioning and histone modifications define relationships between regulatory elements and nearby gene expression in breast epithelial cells. PMID:24885402
NME7 is a functional component of the γ-tubulin ring complex. PMID:24807905
NMR Characterization of Self-Association Domains Promoted by Interactions with LC8 Hub Protein. PMID:24757501
What's that gene (or protein)? Online resources for exploring functions of genes, transcripts, and proteins. PMID:24723265
Functional genomics evidence unearths new moonlighting roles of outer ring coat nucleoporins. PMID:24722254
Spatial rule-based modeling: a method and its application to the human mitotic kinetochore. PMID:24709796
GIP/MZT1 proteins orchestrate nuclear shaping. PMID:24570680
Synthetic genetic array screen identifies PP2A as a therapeutic target in Mad2-overexpressing tumors. PMID:24425774
γ-Tubulin Ring Complexes and EB1 play antagonistic roles in microtubule dynamics and spindle positioning. PMID:24421324
Interaction network of proteins associated with human cytomegalovirus IE2-p86 protein during infection: a proteomic analysis. PMID:24358118
Deducing protein function by forensic integrative cell biology. PMID:24358025
The GIP gamma-tubulin complex-associated proteins are involved in nuclear architecture in Arabidopsis thaliana. PMID:24348487
Spindle assembly checkpoint robustness requires Tpr-mediated regulation of Mad1/Mad2 proteostasis. PMID:24344181
C11ORF24 is a novel type I membrane protein that cycles between the Golgi apparatus and the plasma membrane in Rab6-positive vesicles. PMID:24312644
Network analysis of GWAS data. PMID:24287332
Centrosome dysfunction contributes to chromosome instability, chromoanagenesis, and genome reprograming in cancer. PMID:24282781
A Functional Proteomics Perspective of DBC1 as a Regulator of Transcription. PMID:24273392
The centrosomal adaptor TACC3 and the microtubule polymerase chTOG interact via defined C-terminal subdomains in an Aurora-A kinase-independent manner. PMID:24273164
A quantitative liposome microarray to systematically characterize protein-lipid interactions. PMID:24270602
Mutations in the gene encoding IFT dynein complex component WDR34 cause Jeune asphyxiating thoracic dystrophy. PMID:24183451
CD133 and Ki-67 expression is associated with gastrointestinal stromal tumor prognosis. PMID:24179510
Fodrin in centrosomes: implication of a role of fodrin in the transport of gamma-tubulin complex in brain. PMID:24098540
NDE1 and NDEL1: twin neurodevelopmental proteins with similar 'nature' but different 'nurture'. PMID:24093049
A DNA vaccine targeting p42.3 induces protective antitumor immunity via eliciting cytotoxic CD8+T lymphocytes in a murine melanoma model. PMID:24051432
The molecular basis for kinesin functional specificity during mitosis. PMID:24039047
A critical function of Mad2l2 in primordial germ cell development of mice. PMID:24009519
Mzt1/Tam4, a fission yeast MOZART1 homologue, is an essential component of the γ-tubulin complex and directly interacts with GCP3(Alp6). PMID:24006493
Aurora B and Kif2A control microtubule length for assembly of a functional central spindle during anaphase. PMID:23960144
NuMA phosphorylation by CDK1 couples mitotic progression with cortical dynein function. PMID:23921553
Fission yeast MOZART1/Mzt1 is an essential γ-tubulin complex component required for complex recruitment to the microtubule organizing center, but not its assembly. PMID:23885124
Augmin-dependent microtubule nucleation at microtubule walls in the spindle. PMID:23816620
Overexpression of p42.3 promotes cell growth and tumorigenicity in hepatocellular carcinoma. PMID:23704824
Overexpression of carbonic anhydrase II and Ki-67 proteins in prognosis of gastrointestinal stromal tumors. PMID:23674848
A protein phosphatase 2A complex spatially controls plant cell division. PMID:23673648
Baculovirus expression: tackling the complexity challenge. PMID:23628287
Genomic imbalances in patients with a clinical presentation in the spectrum of Cornelia de Lange syndrome. PMID:23551878
Self-organization of stabilized microtubules by both spindle and midzone mechanisms in Xenopus egg cytosol. PMID:23515222
LGALS3BP regulates centriole biogenesis and centrosome hypertrophy in cancer cells. PMID:23443559
The Colossus of ubiquitylation: decrypting a cellular code. PMID:23438855
A genomic toolkit to investigate kinesin and myosin motor function in cells. PMID:23417121
A kinetic model for RNA-interference of focal adhesions. PMID:23311633
Isotope coded protein labeling coupled immunoprecipitation (ICPL-IP): a novel approach for quantitative protein complex analysis from native tissue. PMID:23268931
Tubulin tyrosine ligase like 12, a TTLL family member with SET- and TTL-like domains and roles in histone and tubulin modifications and mitosis. PMID:23251473
Next-generation proteomics: towards an integrative view of proteome dynamics. PMID:23207911
Proteomics-based methods for discovery, quantification, and validation of protein-protein interactions. PMID:23157382
The microtubule-binding protein Cep170 promotes the targeting of the kinesin-13 depolymerase Kif2b to the mitotic spindle. PMID:23087211
Subdiffraction imaging of centrosomes reveals higher-order organizational features of pericentriolar material. PMID:23086237
Poc1A and Poc1B act together in human cells to ensure centriole integrity. PMID:23015594
Massively parallel measurements of molecular interaction kinetics on a microfluidic platform. PMID:23012409
APC15 mediates CDC20 autoubiquitylation by APC/C(MCC) and disassembly of the mitotic checkpoint complex. PMID:23007861
Analysis of candidate colitis genes in the Gdac1 locus of mice deficient in glutathione peroxidase-1 and -2. PMID:22970191
A census of human soluble protein complexes. PMID:22939629
A genome-scale resource for in vivo tag-based protein function exploration in C. elegans. PMID:22901814
Changes in Ect2 localization couple actomyosin-dependent cell shape changes to mitotic progression. PMID:22898780
SAMBA, a plant-specific anaphase-promoting complex/cyclosome regulator is involved in early development and A-type cyclin stabilization. PMID:22869741
Pivotal Role of AKAP12 in the Regulation of Cellular Adhesion Dynamics: Control of Cytoskeletal Architecture, Cell Migration, and Mitogenic Signaling. PMID:22811901
New insights into subcomplex assembly and modifications of centrosomal proteins. PMID:22800182
Aurora B is regulated by acetylation/deacetylation during mitosis in prostate cancer cells. PMID:22751009
Deformations within moving kinetochores reveal different sites of active and passive force generation. PMID:22722252
Beyond hairballs: The use of quantitative mass spectrometry data to understand protein-protein interactions. PMID:22710165
Misshapen-like kinase 1 (MINK1) is a novel component of striatin-interacting phosphatase and kinase (STRIPAK) and is required for the completion of cytokinesis. PMID:22665485
The APC/C Ubiquitin Ligase: From Cell Biology to Tumorigenesis. PMID:22655255
Proteomic profiling of ATM kinase proficient and deficient cell lines upon blockage of proteasome activity. PMID:22641158
Plk1 negatively regulates PRC1 to prevent premature midzone formation before cytokinesis. PMID:22621898
On the regulation, function, and localization of the DNA-dependent ATPase PICH. PMID:22527115
Cep57, a NEDD1-binding pericentriolar material component, is essential for spindle pole integrity. PMID:22508265
Characterization of the Arabidopsis augmin complex uncovers its critical function in the assembly of the acentrosomal spindle and phragmoplast microtubule arrays. PMID:22505726
An extended γ-tubulin ring functions as a stable platform in microtubule nucleation. PMID:22472440
The GCP3-interacting proteins GIP1 and GIP2 are required for γ-tubulin complex protein localization, spindle integrity, and chromosomal stability. PMID:22427335
A rapid FACS-based strategy to isolate human gene knockin and knockout clones. PMID:22393430
DISC1 conditioned GWAS for psychosis proneness in a large Finnish birth cohort. PMID:22363459
RED, a spindle pole-associated protein, is required for kinetochore localization of MAD1, mitotic progression, and activation of the spindle assembly checkpoint. PMID:22351768
Combined RNAi and localization for functionally dissecting long noncoding RNAs. PMID:22327834
Chromosome- and spindle-pole-derived signals generate an intrinsic code for spindle position and orientation. PMID:22327364
Genome-wide repression of NF-κB target genes by transcription factor MIBP1 and its modulation by O-linked β-N-acetylglucosamine (O-GlcNAc) transferase. PMID:22294689
Analysis of the key elements of FFAT-like motifs identifies new proteins that potentially bind VAP on the ER, including two AKAPs and FAPP2. PMID:22276202
γ-Tubulin 2 nucleates microtubules and is downregulated in mouse early embryogenesis. PMID:22235350
Mutability and mutational spectrum of chromosome transmission fidelity genes. PMID:22198145
Molecular basis for the association of microcephalin (MCPH1) protein with the cell division cycle protein 27 (Cdc27) subunit of the anaphase-promoting complex. PMID:22139841
Structural insights into anaphase-promoting complex function and mechanism. PMID:22084387
Systematic phosphorylation analysis of human mitotic protein complexes. PMID:22067460
Genomes, proteomes, and the central dogma. PMID:22010165
Uncovering ubiquitin and ubiquitin-like signaling networks. PMID:22004258
Microtubule nucleation by γ-tubulin complexes. PMID:21993292
A primary microcephaly protein complex forms a ring around parental centrioles. PMID:21983783
The phylogenomic analysis of the anaphase promoting complex and its targets points to complex and modern-like control of the cell cycle in the last common ancestor of eukaryotes. PMID:21943402
Formation of stable attachments between kinetochores and microtubules depends on the B56-PP2A phosphatase. PMID:21874008
Quantitative phospho-proteomics to investigate the polo-like kinase 1-dependent phospho-proteome. PMID:21857030
Large-scale de novo prediction of physical protein-protein association. PMID:21836163
Whole-exome sequencing identifies compound heterozygous mutations in WDR62 in siblings with recurrent polymicrogyria. PMID:21834044
Emerging Roles for SSeCKS/Gravin/AKAP12 in the Control of Cell Proliferation, Cancer Malignancy, and Barriergenesis. PMID:21779438
emb-1 encodes the APC16 subunit of the Caenorhabditis elegans anaphase-promoting complex. PMID:21775471
Time-resolved human kinome RNAi screen identifies a network regulating mitotic-events as early regulators of cell proliferation. PMID:21765947
Crenarchaeal CdvA forms double-helical filaments containing DNA and interacts with ESCRT-III-like CdvB. PMID:21760923
Augmin plays a critical role in organizing the spindle and phragmoplast microtubule arrays in Arabidopsis. PMID:21750235
PICH and BLM limit histone association with anaphase centromeric DNA threads and promote their resolution. PMID:21743438
Spatial exclusivity combined with positive and negative selection of phosphorylation motifs is the basis for context-dependent mitotic signaling. PMID:21712545
RAD21 cooperates with pluripotency transcription factors in the maintenance of embryonic stem cell identity. PMID:21589869
Building protein-protein interaction networks with proteomics and informatics tools. PMID:21566121
A high-resolution C. elegans essential gene network based on phenotypic profiling of a complex tissue. PMID:21529718
From RNAi screens to molecular function in embryonic stem cells. PMID:21526416
Processive ubiquitin chain formation by the anaphase-promoting complex. PMID:21477659
Microtubule stabilization in vivo by nucleation-incompetent γ-tubulin complex. PMID:21444751
Novel asymmetrically localizing components of human centrosomes identified by complementary proteomics methods. PMID:21399614
The function of spliceosome components in open mitosis. PMID:21327086
Augmented annotation of the Schizosaccharomyces pombe genome reveals additional genes required for growth and viability. PMID:21270388
Micropilot: automation of fluorescence microscopy-based imaging for systems biology. PMID:21258339
Systems biology in immunology: a computational modeling perspective. PMID:21219182
Anastral spindle assembly and γ-tubulin in Drosophila oocytes. PMID:21208439
Where gene discovery turns into systems biology: genome-scale RNAi screens in Drosophila. PMID:21197652
DISC1-binding proteins in neural development, signalling and schizophrenia. PMID:21195721
CDK5RAP2 stimulates microtubule nucleation by the gamma-tubulin ring complex. PMID:21135143
Lesson from the stoichiometry determination of the cohesin complex: a short protease mediated elution increases the recovery from cross-linked antibody-conjugated beads. PMID:21043528
Building mitotic chromosomes. PMID:20974528
Cep120 is asymmetrically localized to the daughter centriole and is essential for centriole assembly. PMID:20956381
Mutations in WDR62, encoding a centrosome-associated protein, cause microcephaly with simplified gyri and abnormal cortical architecture. PMID:20890278
The gammaTuRC revisited: a comparative analysis of interphase and mitotic human gammaTuRC redefines the set of core components and identifies the novel subunit GCP8. PMID:20861304
Topographic studies of the GroEL-GroES chaperonin complex by chemical cross-linking using diformyl ethynylbenzene: the power of high resolution electron transfer dissociation for determination of both peptide sequences and their attachment sites. PMID:20813910
The protein composition of mitotic chromosomes determined using multiclassifier combinatorial proteomics. PMID:20813266
Descriptive no more: the dawn of high-throughput microscopy. PMID:20667736
Human ESCRT-III and VPS4 proteins are required for centrosome and spindle maintenance. PMID:20616062
A genome-scale DNA repair RNAi screen identifies SPG48 as a novel gene associated with hereditary spastic paraplegia. PMID:20613862
Next-generation genomics: an integrative approach. PMID:20531367
Discovering Mozart. PMID:20521367
Quantitative proteomics combined with BAC TransgeneOmics reveals in vivo protein interactions. PMID:20479470
The next frontier of systems biology: higher-order and interspecies interactions. PMID:20441613
Cell cycle: dissecting mitosis. PMID:20419887
APC16 is a conserved subunit of the anaphase-promoting complex/cyclosome. PMID:20392738 -
Experimental and computational framework for a dynamic protein atlas of human cell division
PubMed citations: 39.
39 articles citing: Experimental and computational framework for a dynamic protein atlas of human cell division
Uncovering the mode of action of engineered T cells in patient cancer organoids. PMID:35879361
Function and regulation of transcription factors during mitosis-to-G1 transition. PMID:35642493
Extra kinetic dimensions for label discrimination. PMID:35304491
OpenCell: Endogenous tagging for the cartography of human cellular organization. PMID:35271311
Efficient and error-free fluorescent gene tagging in human organoids without double-strand DNA cleavage. PMID:35089911
Volumetric morphometry reveals spindle width as the best predictor of mammalian spindle scaling. PMID:34787651
Single-cell landscape of nuclear configuration and gene expression during stem cell differentiation and X inactivation. PMID:34579774
miRNATissueAtlas2: an update to the human miRNA tissue atlas. PMID:34570238
CTCF and transcription influence chromatin structure re-configuration after mitosis. PMID:34453048
CTCF chromatin residence time controls three-dimensional genome organization, gene expression and DNA methylation in pluripotent cells. PMID:34326481
Dynamic contrast with reversibly photoswitchable fluorescent labels for imaging living cells. PMID:34122788
Permitted and restricted steps of human kinetochore assembly in mitotic cell extracts. PMID:33956511
Regression plane concept for analysing continuous cellular processes with machine learning. PMID:33953203
Data science in cell imaging. PMID:33795377
Cohesin: behind dynamic genome topology and gene expression reprogramming. PMID:33766521
Imaging mitotic processes in three dimensions with lattice light-sheet microscopy. PMID:33694045
Estimating Cellular Abundances of Halo-tagged Proteins in Live Mammalian Cells by Flow Cytometry. PMID:33654751
Quantifying the roles of space and stochasticity in computer simulations for cell biology and cellular biochemistry. PMID:33237849
An image-based data-driven analysis of cellular architecture in a developing tissue. PMID:32501214
Dynamic regulation of histone modifications and long-range chromosomal interactions during postmitotic transcriptional reactivation. PMID:32499403
Digital Spindle: A New Way to Explore Mitotic Functions by Whole Cell Data Collection and a Computational Approach. PMID:32438637
Automated 3D light-sheet screening with high spatiotemporal resolution reveals mitotic phenotypes. PMID:32295847
Chemogenetic Control of Nanobodies. PMID:32066961
ESCO1 and CTCF enable formation of long chromatin loops by protecting cohesinSTAG1 from WAPL. PMID:32065581
Membrane and organelle dynamics during cell division. PMID:32034394
Chromatin structure dynamics during the mitosis-to-G1 phase transition. PMID:31776509
A chromosome folding intermediate at the condensin-to-cohesin transition during telophase. PMID:31685986
CTCF and cellular heterogeneity. PMID:31632638
Evaluating phase separation in live cells: diagnosis, caveats, and functional consequences. PMID:31594803
Borealin-nucleosome interaction secures chromosome association of the chromosomal passenger complex. PMID:31570499
Spatial and temporal tools for building a human cell atlas. PMID:31465255
From observing to predicting single-cell structure and function with high-throughput/high-content microscopy. PMID:31243141
Determining cellular CTCF and cohesin abundances to constrain 3D genome models. PMID:31205001
Absolute quantification of cohesin, CTCF and their regulators in human cells. PMID:31204999
Dissecting the mechanisms of cell division. PMID:31175154
Towards Building a Plant Cell Atlas. PMID:30777643
Spatial proteomics: a powerful discovery tool for cell biology. PMID:30659282
Transcription factor activity and nucleosome organization in mitosis. PMID:30655337
CTCF sites display cell cycle-dependent dynamics in factor binding and nucleosome positioning. PMID:30655336
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biological imaging
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version: FAIRsharing.org: MitoCheck; MitoCheck; DOI: https://doi.org/10.25504/FAIRsharing.j4ebq1; Last edited: April 26, 2021, 4:04 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
high-content screen
metasource: Fairsharing.org
version: FAIRsharing.org: MitoCheck; MitoCheck; DOI: https://doi.org/10.25504/FAIRsharing.j4ebq1; Last edited: April 26, 2021, 4:04 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
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biological imaging
metasource: Fairsharing.orgversion: FAIRsharing.org: MitoCheck; MitoCheck; DOI: https://doi.org/10.25504/FAIRsharing.j4ebq1; Last edited: April 26, 2021, 4:04 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
high-content screen
metasource: Fairsharing.orgversion: FAIRsharing.org: MitoCheck; MitoCheck; DOI: https://doi.org/10.25504/FAIRsharing.j4ebq1; Last edited: April 26, 2021, 4:04 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
biological imaging high-content screen
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