Knottin database
Names
More detailed information about this field from each metasource.
Knottin database
metasource: Fairsharing.org
version: FAIRsharing.org: KNOTTIN; Knottin database; DOI: https://doi.org/10.25504/FAIRsharing.hpyy7d; Last edited: Jan. 8, 2019, 1:16 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657
KNOTTIN
metasource: Fairsharing.org
version: FAIRsharing.org: KNOTTIN; Knottin database; DOI: https://doi.org/10.25504/FAIRsharing.hpyy7d; Last edited: Jan. 8, 2019, 1:16 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
Names
More detailed information about this field from each metasource.
Knottin database
metasource: Fairsharing.orgversion: FAIRsharing.org: KNOTTIN; Knottin database; DOI: https://doi.org/10.25504/FAIRsharing.hpyy7d; Last edited: Jan. 8, 2019, 1:16 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657
KNOTTIN
metasource: Fairsharing.orgversion: FAIRsharing.org: KNOTTIN; Knottin database; DOI: https://doi.org/10.25504/FAIRsharing.hpyy7d; Last edited: Jan. 8, 2019, 1:16 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
Names
More detailed information about this field from each metasource.
Knottin database
metasource: Fairsharing.orgversion: FAIRsharing.org: KNOTTIN; Knottin database; DOI: https://doi.org/10.25504/FAIRsharing.hpyy7d; Last edited: Jan. 8, 2019, 1:16 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657
KNOTTIN
metasource: Fairsharing.orgversion: FAIRsharing.org: KNOTTIN; Knottin database; DOI: https://doi.org/10.25504/FAIRsharing.hpyy7d; Last edited: Jan. 8, 2019, 1:16 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
The KNOTTIN database provides standardized data on the knottin structural family (also referred to as the "Inhibitor Cystine Knot (ICK) motif/family/fold").
Description
More detailed information about this field from each metasource.
The KNOTTIN database provides standardized data on the knottin structural family (also referred to as the "Inhibitor Cystine Knot (ICK) motif/family/fold").
metasource: Fairsharing.orgversion: FAIRsharing.org: KNOTTIN; Knottin database; DOI: https://doi.org/10.25504/FAIRsharing.hpyy7d; Last edited: Jan. 8, 2019, 1:16 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
Database of knottins - small proteins with an unusual "disulfide through disulfide" knot
metasource: Nucleic Acid Research database catalogueversion: extracted_at: 2022-11-04T11:16:25.468657
Webpage:
http://knottin.cbs.cnrs.fr/Webpage
More detailed information about this field from each metasource.
http://knottin.cbs.cnrs.fr/
metasource: Fairsharing.orgversion: FAIRsharing.org: KNOTTIN; Knottin database; DOI: https://doi.org/10.25504/FAIRsharing.hpyy7d; Last edited: Jan. 8, 2019, 1:16 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657
Publications:
Publications
More detailed information about this field from each metasource.
KNOTTIN: the knottin or inhibitor cystine knot scaffold in 2007
PMID: 18025039
metasource: Fairsharing.org
version: FAIRsharing.org: KNOTTIN; Knottin database; DOI: https://doi.org/10.25504/FAIRsharing.hpyy7d; Last edited: Jan. 8, 2019, 1:16 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
Publications
More detailed information about this field from each metasource.
KNOTTIN: the knottin or inhibitor cystine knot scaffold in 2007
PMID: 18025039
metasource: Fairsharing.org
version: FAIRsharing.org: KNOTTIN; Knottin database; DOI: https://doi.org/10.25504/FAIRsharing.hpyy7d; Last edited: Jan. 8, 2019, 1:16 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
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KNOTTIN: the knottin or inhibitor cystine knot scaffold in 2007
PubMed citations: 57.
57 articles citing: KNOTTIN: the knottin or inhibitor cystine knot scaffold in 2007
Immunomodulatory potential of black soldier fly larvae: applications beyond nutrition in animal feeding programs. PMID:35854966
Molecular diversity and evolutionary trends of cysteine-rich peptides from the venom glands of Chinese spider Heteropoda venatoria. PMID:33547373
Pathogenicity-associated protein domains: The fiercely-conserved evolutionary signatures. PMID:32363241
Alternative Transcription at Venom Genes and Its Role as a Complementary Mechanism for the Generation of Venom Complexity in the Common House Spider. PMID:31431897
Isolation, characterization, cloning and bioinformatics analysis of a novel receptor from black cut worm (Agrotis ipsilon) of Bacillus thuringiensis vip 3Aa toxins. PMID:31303843
First Transcriptome Analysis of Iranian Scorpion, Mesobuthus Eupeus Venom Gland. PMID:30568706
Secreted Cysteine-Rich Repeat Proteins "SCREPs": A Novel Multi-Domain Architecture. PMID:30524283
Protecting Encapsulin Nanoparticles with Cysteine-Knot Miniproteins. PMID:30047270
Molecular diversity and function of jasmintides from Jasminum sambac. PMID:29996766
Classes, Databases, and Prediction Methods of Pharmaceutically and Commercially Important Cystine-Stabilized Peptides. PMID:29921767
Assigning biological function using hidden signatures in cystine-stabilized peptide sequences. PMID:29899538
Biochemical and MALDI-TOF Mass Spectrometric Characterization of a Novel Native and Recombinant Cystine Knot Miniprotein from Solanum tuberosum subsp. andigenum cv. Churqueña. PMID:29495576
Analysis of the Salivary Gland Transcriptome of Unfed and Partially Fed Amblyomma sculptum Ticks and Descriptive Proteome of the Saliva. PMID:29209593
KNOTTIN: the database of inhibitor cystine knot scaffold after 10 years, toward a systematic structure modeling. PMID:29136213
β-Ginkgotides: Hyperdisulfide-constrained peptides from Ginkgo biloba. PMID:28733600
Molecular Characterization and Biodiversity of a Putative Chlorotoxin from the Iranian Yellow Scorpion Odontobuthus doriae. PMID:28415833
Peptidomic and transcriptomic profiling of four distinct spider venoms. PMID:28306751
In vitro-engineered non-antibody protein therapeutics. PMID:28271446
Identification and Characterization of Roseltide, a Knottin-type Neutrophil Elastase Inhibitor Derived from Hibiscus sabdariffa. PMID:27991569
Molecular cloning and in silico characterization of knottin peptide, U2-SCRTX-Lit2, from brown spider (Loxosceles intermedia) venom glands. PMID:27488102
A sodium channel inhibitor ISTX-I with a novel structure provides a new hint at the evolutionary link between two toxin folds. PMID:27407029
Plant cystine-knot peptides: pharmacological perspectives. PMID:26987851
Computational analysis of the MCoTI-II plant defence knottin reveals a novel intermediate conformation that facilitates trypsin binding. PMID:26975976
Genome-wide analysis identifies gain and loss/change of function within the small multigenic insecticidal Albumin 1 family of Medicago truncatula. PMID:26964738
Structural Basis for the Inhibition of Voltage-gated Sodium Channels by Conotoxin μO§-GVIIJ. PMID:26817840
The Cystine Knot Is Responsible for the Exceptional Stability of the Insecticidal Spider Toxin ω-Hexatoxin-Hv1a. PMID:26516914
Genome-Wide Reprogramming of Transcript Architecture by Temperature Specifies the Developmental States of the Human Pathogen Histoplasma. PMID:26177267
PredSTP: a highly accurate SVM based model to predict sequential cystine stabilized peptides. PMID:26142484
Bioinformatics-Aided Venomics. PMID:26110505
The knottin-like Blufensin family regulates genes involved in nuclear import and the secretory pathway in barley-powdery mildew interactions. PMID:26089830
Fragmentation follows structure: top-down mass spectrometry elucidates the topology of engineered cystine-knot miniproteins. PMID:25303319
Dramatic expansion of the black widow toxin arsenal uncovered by multi-tissue transcriptomics and venom proteomics. PMID:24916504
Clawing through evolution: toxin diversification and convergence in the ancient lineage Chilopoda (centipedes). PMID:24847043
Discovery, synthesis, and structure-activity relationships of conotoxins. PMID:24720541
99mTc-labeled cystine knot peptide targeting integrin αvβ6 for tumor SPECT imaging. PMID:24524409
Combinatorial optimization of cystine-knot peptides towards high-affinity inhibitors of human matriptase-1. PMID:24146945
Novel inhibitor cystine knot peptides from Momordica charantia. PMID:24116036
Isolation of an orally active insecticidal toxin from the venom of an Australian tarantula. PMID:24039872
Engineering agatoxin, a cystine-knot peptide from spider venom, as a molecular probe for in vivo tumor imaging. PMID:23573262
Formation of cystine slipknots in dimeric proteins. PMID:23520470
The insecticidal neurotoxin Aps III is an atypical knottin peptide that potently blocks insect voltage-gated sodium channels. PMID:23473802
Evolution of a horizontally acquired legume gene, albumin 1, in the parasitic plant Phelipanche aegyptiaca and related species. PMID:23425243
Discovery of linear cyclotides in monocot plant Panicum laxum of Poaceae family provides new insights into evolution and distribution of cyclotides in plants. PMID:23195955
Chemical synthesis, backbone cyclization and oxidative folding of cystine-knot peptides: promising scaffolds for applications in drug design. PMID:23095896
Dissecting a role of evolutionary-conserved but noncritical disulfide bridges in cysteine-rich peptides using ω-conotoxin GVIA and its selenocysteine analogs. PMID:22782563
Cupricyclins, novel redox-active metallopeptides based on conotoxins scaffold. PMID:22319584
Cyclotides, a novel ultrastable polypeptide scaffold for drug discovery. PMID:22204428
Isolation, amino acid sequence and biological activities of novel long-chain polyamine-associated peptide toxins from the sponge Axinyssa aculeata. PMID:21830292
Common structural traits for cystine knot domain of the TGFβ superfamily of proteins and three-fingered ectodomain of their cellular receptors. PMID:21369710
Diversity of conotoxin types from Conus californicus reflects a diversity of prey types and a novel evolutionary history. PMID:21172372
A diverse family of novel peptide toxins from an unusual cone snail, Conus californicus. PMID:21147978
Optimizing structural modeling for a specific protein scaffold: knottins or inhibitor cystine knots. PMID:21029427
Site-specific effects of diselenide bridges on the oxidative folding of a cystine knot peptide, omega-selenoconotoxin GVIA. PMID:20175537
Interrogating and predicting tolerated sequence diversity in protein folds: application to E. elaterium trypsin inhibitor-II cystine-knot miniprotein. PMID:19730675
Comparative structure analyses of cystine knot-containing molecules with eight aminoacyl ring including glycoprotein hormones (GPH) alpha and beta subunits and GPH-related A2 (GPA2) and B5 (GPB5) molecules. PMID:19715619
Aphids acquired symbiotic genes via lateral gene transfer. PMID:19284544
Knottin cyclization: impact on structure and dynamics. PMID:19077275
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Tags
More detailed information about this field from each metasource.
small molecule
metasource: Fairsharing.org
version: FAIRsharing.org: KNOTTIN; Knottin database; DOI: https://doi.org/10.25504/FAIRsharing.hpyy7d; Last edited: Jan. 8, 2019, 1:16 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
structure
metasource: Fairsharing.org
version: FAIRsharing.org: KNOTTIN; Knottin database; DOI: https://doi.org/10.25504/FAIRsharing.hpyy7d; Last edited: Jan. 8, 2019, 1:16 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
protein sequence databases
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657
databases of individual protein families
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657
Tags
More detailed information about this field from each metasource.
small molecule
metasource: Fairsharing.orgversion: FAIRsharing.org: KNOTTIN; Knottin database; DOI: https://doi.org/10.25504/FAIRsharing.hpyy7d; Last edited: Jan. 8, 2019, 1:16 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
structure
metasource: Fairsharing.orgversion: FAIRsharing.org: KNOTTIN; Knottin database; DOI: https://doi.org/10.25504/FAIRsharing.hpyy7d; Last edited: Jan. 8, 2019, 1:16 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
protein sequence databases
metasource: Nucleic Acid Research database catalogueversion: extracted_at: 2022-11-04T11:16:25.468657
databases of individual protein families
metasource: Nucleic Acid Research database catalogueversion: extracted_at: 2022-11-04T11:16:25.468657
small molecule structure protein sequence protein family
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