IRESite
Names
More detailed information about this field from each metasource.
IRESite
metasource: Fairsharing.org
version: FAIRsharing.org: IRESite; IRESite; DOI: https://doi.org/10.25504/FAIRsharing.kd39j4; Last edited: Jan. 8, 2019, 1:16 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657
metasource: bio.tools
version: extracted_at: 2022-11-04T11:26:21.276445
iresite
metasource: bio.tools
version: extracted_at: 2022-11-04T11:26:21.276445
Names
More detailed information about this field from each metasource.
IRESite
metasource: Fairsharing.orgversion: FAIRsharing.org: IRESite; IRESite; DOI: https://doi.org/10.25504/FAIRsharing.kd39j4; Last edited: Jan. 8, 2019, 1:16 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657
metasource: bio.tools
version: extracted_at: 2022-11-04T11:26:21.276445
iresite
metasource: bio.toolsversion: extracted_at: 2022-11-04T11:26:21.276445
Names
More detailed information about this field from each metasource.
IRESite
metasource: Fairsharing.orgversion: FAIRsharing.org: IRESite; IRESite; DOI: https://doi.org/10.25504/FAIRsharing.kd39j4; Last edited: Jan. 8, 2019, 1:16 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657
metasource: bio.tools
version: extracted_at: 2022-11-04T11:26:21.276445
iresite
metasource: bio.toolsversion: extracted_at: 2022-11-04T11:26:21.276445
The IRESite database presents information about experimentally studied IRES (Internal Ribosome Entry Site) segments. IRES regions are known to attract the eukaryotic ribosomal translation initiation complex and thus promote translation initiation independently of the presence of the commonly utilized 5'-terminal 7mG cap structure.
Description
More detailed information about this field from each metasource.
The IRESite database presents information about experimentally studied IRES (Internal Ribosome Entry Site) segments. IRES regions are known to attract the eukaryotic ribosomal translation initiation complex and thus promote translation initiation independently of the presence of the commonly utilized 5'-terminal 7mG cap structure.
metasource: Fairsharing.orgversion: FAIRsharing.org: IRESite; IRESite; DOI: https://doi.org/10.25504/FAIRsharing.kd39j4; Last edited: Jan. 8, 2019, 1:16 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
IRESite is a searchable collection of data concerning the Internal Ribosome Entry Segments (IRES) both of viral and cellular origin. IRESs are the RNA regions which are mostly defined functionally by their ability to attract a eukaryotic ribosomal translation initiation complex independently of presence of the commonly utilized 5'-terminal 7mG cap structure and thus to promote translation initiation even at the internal part of the RNA molecule. IRESite can provide a broad set of information referring to particular IRES - briefly: primary sequence data, functional data, RNA structure and possible ribosomal RNA complementarity data, RNA:protein interaction data, links to primary databases, information about the relevant experiments and more. Most of the data are not available in the primary databases and are manually extracted from literature sources by IRESite curators. New data can also be submitted through the publicly available IRESite web interface after creating a personal account, however their release needs the curators' approval. Brief graphical overview of the database is present at http://www.iresite.org/docs/iresite.pdf
metasource: Nucleic Acid Research database catalogueversion: extracted_at: 2022-11-04T11:16:25.468657
Our database presents experimental evidence of many eukaryotic viral and cellular internal ribosome entry site (IRES) regions.
metasource: bio.toolsversion: extracted_at: 2022-11-04T11:26:21.276445
Webpage:
http://www.iresite.orgWebpage
More detailed information about this field from each metasource.
http://www.iresite.org
metasource: Fairsharing.orgversion: FAIRsharing.org: IRESite; IRESite; DOI: https://doi.org/10.25504/FAIRsharing.kd39j4; Last edited: Jan. 8, 2019, 1:16 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
http://www.iresite.org/
metasource: Nucleic Acid Research database catalogueversion: extracted_at: 2022-11-04T11:16:25.468657
http://iresite.org/
metasource: bio.toolsversion: extracted_at: 2022-11-04T11:26:21.276445
Licence:
Name: NIH Web Policies and NoticesLicence name
More detailed information about this field from each metasource.
NIH Web Policies and Notices
metasource: Fairsharing.orgversion: FAIRsharing.org: IRESite; IRESite; DOI: https://doi.org/10.25504/FAIRsharing.kd39j4; Last edited: Jan. 8, 2019, 1:16 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
Licence URL
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https://www.nih.gov/web-policies-notices
metasource: Fairsharing.orgversion: FAIRsharing.org: IRESite; IRESite; DOI: https://doi.org/10.25504/FAIRsharing.kd39j4; Last edited: Jan. 8, 2019, 1:16 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
Publications:
Publications
More detailed information about this field from each metasource.
IRESite--a tool for the examination of viral and cellular internal ribosome entry sites
PMID: 19917642
metasource: Fairsharing.org
version: FAIRsharing.org: IRESite; IRESite; DOI: https://doi.org/10.25504/FAIRsharing.kd39j4; Last edited: Jan. 8, 2019, 1:16 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
IRESite: the database of experimentally verified IRES structures (www.iresite.org)
PMID: 16381829
metasource: Fairsharing.org
version: FAIRsharing.org: IRESite; IRESite; DOI: https://doi.org/10.25504/FAIRsharing.kd39j4; Last edited: Jan. 8, 2019, 1:16 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
http://dx.doi.org/10.1093/nar/gkp981
metasource: bio.tools
version: extracted_at: 2022-11-04T11:26:21.276445
Publications
More detailed information about this field from each metasource.
IRESite--a tool for the examination of viral and cellular internal ribosome entry sites
PMID: 19917642
metasource: Fairsharing.org
version: FAIRsharing.org: IRESite; IRESite; DOI: https://doi.org/10.25504/FAIRsharing.kd39j4; Last edited: Jan. 8, 2019, 1:16 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
IRESite: the database of experimentally verified IRES structures (www.iresite.org)
PMID: 16381829
metasource: Fairsharing.org
version: FAIRsharing.org: IRESite; IRESite; DOI: https://doi.org/10.25504/FAIRsharing.kd39j4; Last edited: Jan. 8, 2019, 1:16 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
http://dx.doi.org/10.1093/nar/gkp981
metasource: bio.toolsversion: extracted_at: 2022-11-04T11:26:21.276445
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IRESite--a tool for the examination of viral and cellular internal ribosome entry sites
PubMed citations: 80.
80 articles citing: IRESite--a tool for the examination of viral and cellular internal ribosome entry sites
Roles of circRNAs in hematological malignancies. PMID:35840998
RNA-Binding Proteins as Regulators of Internal Initiation of Viral mRNA Translation. PMID:35215780
Reversal of G-Quadruplexes' Role in Translation Control When Present in the Context of an IRES. PMID:35204814
circSLC41A1 Resists Porcine Granulosa Cell Apoptosis and Follicular Atresia by Promoting SRSF1 through miR-9820-5p Sponging. PMID:35163432
Introduction to Bioinformatics Resources for Post-transcriptional Regulation of Gene Expression. PMID:34694601
Structured elements drive extensive circular RNA translation. PMID:34437836
Circular RNA translation, a path to hidden proteome. PMID:34342387
Comprehensive Analysis of Peripheral Exosomal circRNAs in Large Artery Atherosclerotic Stroke. PMID:34239876
Translation role of circRNAs in cancers. PMID:34097315
Current Practice in Bicistronic IRES Reporter Use: A Systematic Review. PMID:34068921
Human IRES Atlas: an integrative platform for studying IRES-driven translational regulation in humans. PMID:33942874
Combined Transcriptomic and Proteomic Analysis of Perk Toxicity Pathways. PMID:33925631
Extreme conservation encodes the structural dynamics and function of 5' UTRs. PMID:33888910
Circular RNAs in Human Cancer. PMID:33537235
Internal Ribosome Entry Sites Mediate Cap-Independent Translation of Bmi1 in Nasopharyngeal Carcinoma. PMID:33014838
Siblings or doppelgängers? Deciphering the evolution of structured cis-regulatory RNAs beyond homology. PMID:32869842
Translation Regulation by eIF2α Phosphorylation and mTORC1 Signaling Pathways in Non-Communicable Diseases (NCDs). PMID:32722591
Regulation of Epithelial-to-Mesenchymal Transition by Alternative Translation Initiation Mechanisms and Its Implications for Cancer Metastasis. PMID:32517298
The switch-like expression of heme-regulated kinase 1 mediates neuronal proteostasis following proteasome inhibition. PMID:32329716
Endoplasmic reticulum stress: New insights into the pathogenesis and treatment of retinal degenerative diseases. PMID:32272207
Translational Regulations in Response to Endoplasmic Reticulum Stress in Cancers. PMID:32111004
Translation and functional roles of circular RNAs in human cancer. PMID:32059672
Closing the circle: current state and perspectives of circular RNA databases. PMID:31998941
Messenger RNAs of Yeast Virus-Like Elements Contain Non-templated 5' Poly(A) Leaders, and Their Expression Is Independent of eIF4E and Pab1. PMID:31736885
ILF3 contributes to the establishment of the antiviral type I interferon program. PMID:31701124
Identification and characterization of circRNAs as competing endogenous RNAs for miRNA-mRNA in colorectal cancer. PMID:31579577
IRES-mediated cap-independent translation, a path leading to hidden proteome. PMID:31504667
IRESpy: an XGBoost model for prediction of internal ribosome entry sites. PMID:31362694
RNA-mediated translation regulation in viral genomes: computational advances in the recognition of sequences and structures. PMID:31204430
Marine RNA Virus Quasispecies Are Distributed throughout the Oceans. PMID:30944212
The PERK Branch of the Unfolded Protein Response Promotes DLL4 Expression by Activating an Alternative Translation Mechanism. PMID:30691003
Exploring the Role of AUG Triplets in Human Cap-Independent Translation Enhancing Elements. PMID:30371061
Circular RNAs in the cardiovascular system. PMID:30159434
Human rhinovirus internal ribosome entry site element enhances transgene expression in transfected CHO-S cells. PMID:29703950
Know Your Enemy: Successful Bioinformatic Approaches to Predict Functional RNA Structures in Viral RNAs. PMID:29354101
Circular RNAs: Biogenesis, Function, and a Role as Possible Cancer Biomarkers. PMID:29349062
Functional 5' UTR mRNA structures in eukaryotic translation regulation and how to find them. PMID:29165424
Sequence features of viral and human Internal Ribosome Entry Sites predictive of their activity. PMID:28922394
Ribosome profiling reveals translational regulation of mammalian cells in response to hypoxic stress. PMID:28826393
Plant dehydrins: shedding light on structure and expression patterns of dehydrin gene family in barley. PMID:28389925
Differential Sensitivity of Target Genes to Translational Repression by miR-17~92. PMID:28241004
Advancing viral RNA structure prediction: measuring the thermodynamics of pyrimidine-rich internal loops. PMID:28213527
Netrin-1 Protects Hepatocytes Against Cell Death Through Sustained Translation During the Unfolded Protein Response. PMID:28174720
PRMT5 regulates IRES-dependent translation via methylation of hnRNP A1. PMID:28115626
Mammalian Polycistronic mRNAs and Disease. PMID:28012572
More than just scanning: the importance of cap-independent mRNA translation initiation for cellular stress response and cancer. PMID:27913822
Characterization of new transposable element sub-families from white clover (Trifolium repens) using PCR amplification. PMID:27671023
Roles of different IRES-dependent FGF2 isoforms in the acquisition of the major aggressive features of human metastatic melanoma. PMID:27558498
Toward a systematic understanding of translational regulatory elements in human and viruses. PMID:27442807
IRESPred: Web Server for Prediction of Cellular and Viral Internal Ribosome Entry Site (IRES). PMID:27264539
A Novel Method for Gene-Specific Enhancement of Protein Translation by Targeting 5'UTRs of Selected Tumor Suppressors. PMID:27171412
Endoplasmic Reticulum Stress Induced Synthesis of a Novel Viral Factor Mediates Efficient Replication of Genotype-1 Hepatitis E Virus. PMID:27035822
The Human Papillomavirus 16 E7 Oncoprotein Attenuates AKT Signaling To Promote Internal Ribosome Entry Site-Dependent Translation and Expression of c-MYC. PMID:27030265
CircInteractome: A web tool for exploring circular RNAs and their interacting proteins and microRNAs. PMID:26669964
IRES-dependent translated genes in fungi: computational prediction, phylogenetic conservation and functional association. PMID:26666532
A deep learning framework for modeling structural features of RNA-binding protein targets. PMID:26467480
Regulation of human PTCH1b expression by different 5' untranslated region cis-regulatory elements. PMID:25826662
Translation of 5' leaders is pervasive in genes resistant to eIF2 repression. PMID:25621764
Molecular biology: Entry signals control development. PMID:25409148
TRAP1-dependent regulation of p70S6K is involved in the attenuation of protein synthesis and cell migration: relevance in human colorectal tumors. PMID:24962791
The characterization of RNA viruses in tropical seawater using targeted PCR and metagenomics. PMID:24939887
The kissing-loop T-shaped structure translational enhancer of Pea enation mosaic virus can bind simultaneously to ribosomes and a 5' proximal hairpin. PMID:23986599
VEGF-A mRNA processing, stability and translation: a paradigm for intricate regulation of gene expression at the post-transcriptional level. PMID:23851566
Genome-wide profiling of human cap-independent translation-enhancing elements. PMID:23770754
Structure of the full-length HCV IRES in solution. PMID:23511476
The current status of vertebrate cellular mRNA IRESs. PMID:23378589
Toward a genome-wide landscape of translational control. PMID:23209130
Translational mechanisms at work in the cohesinopathies. PMID:23138777
Tuning the engine: an introduction to resources on post-transcriptional regulation of gene expression. PMID:22995832
Mining Functional Elements in Messenger RNAs: Overview, Challenges, and Perspectives. PMID:22639614
Topology of the human and mouse m6A RNA methylomes revealed by m6A-seq. PMID:22575960
A unifying model for mTORC1-mediated regulation of mRNA translation. PMID:22552098
Global or local? Predicting secondary structure and accessibility in mRNAs. PMID:22373926
Modulation of gurken translation by insulin and TOR signaling in Drosophila. PMID:22328499
Analysis of the 5' untranslated region (5'UTR) of the alcohol oxidase 1 (AOX1) gene in recombinant protein expression in Pichia pastoris. PMID:22285974
The structures of nonprotein-coding RNAs that drive internal ribosome entry site function. PMID:22215521
The 2012 Nucleic Acids Research Database Issue and the online Molecular Biology Database Collection. PMID:22144685
An internal ribosome entry site directs translation of the 3'-gene from Pelargonium flower break virus genomic RNA: implications for infectivity. PMID:21818349
Cellular IRES-mediated translation: the war of ITAFs in pathophysiological states. PMID:21220943
Analysis of the protein expression changes during taxol-induced apoptosis under translation inhibition conditions. PMID:20717708 -
IRESite: the database of experimentally verified IRES structures (www.iresite.org)
PubMed citations: 36.
36 articles citing: IRESite: the database of experimentally verified IRES structures (www.iresite.org)
Role of the receptor for activated C kinase 1 during viral infection. PMID:35763066
RNA-Binding Proteins as Regulators of Internal Initiation of Viral mRNA Translation. PMID:35215780
Reversal of G-Quadruplexes' Role in Translation Control When Present in the Context of an IRES. PMID:35204814
circSLC41A1 Resists Porcine Granulosa Cell Apoptosis and Follicular Atresia by Promoting SRSF1 through miR-9820-5p Sponging. PMID:35163432
circ-EIF6 encodes EIF6-224aa to promote TNBC progression via stabilizing MYH9 and activating the Wnt/beta-catenin pathway. PMID:34450253
Sp1-Mediated circRNA circHipk2 Regulates Myogenesis by Targeting Ribosomal Protein Rpl7. PMID:34066653
Coordination of transcriptional and translational regulations in human epithelial cells infected by Listeria monocytogenes. PMID:32584699
IRESbase: A Comprehensive Database of Experimentally Validated Internal Ribosome Entry Sites. PMID:32512182
Discordant Activity of Kaempferol Towards Dengue Virus and Japanese Encephalitis Virus. PMID:32164193
Emerging role of tumor-related functional peptides encoded by lncRNA and circRNA. PMID:32019587
Current prevalence status of gastric cancer and recent studies on the roles of circular RNAs and methods used to investigate circular RNAs. PMID:31428168
Host targeted antiviral (HTA): functional inhibitor compounds of scaffold protein RACK1 inhibit herpes simplex virus proliferation. PMID:31143369
Circular RNAs: Functions and Prospects in Glioma. PMID:30460608
A peptide encoded by circular form of LINC-PINT suppresses oncogenic transcriptional elongation in glioblastoma. PMID:30367041
The ribosomal RPL10 R98S mutation drives IRES-dependent BCL-2 translation in T-ALL. PMID:29930300
A novel protein encoded by the circular form of the SHPRH gene suppresses glioma tumorigenesis. PMID:29343848
Novel Role of FBXW7 Circular RNA in Repressing Glioma Tumorigenesis. PMID:28903484
Poly(ADP-ribose) polymerase-13 and RNA regulation in immunity and cancer. PMID:25851173
The impact of RNA structure on coding sequence evolution in both bacteria and eukaryotes. PMID:24758737
TISdb: a database for alternative translation initiation in mammalian cells. PMID:24203712
Internal ribosome entry segment activity of ATXN8 opposite strand RNA. PMID:24040107
Translational control of gene expression in the gonadotrope. PMID:24035865
Hyperglycemia mediates a shift from cap-dependent to cap-independent translation via a 4E-BP1-dependent mechanism. PMID:23434932
Alternative Mechanisms to Initiate Translation in Eukaryotic mRNAs. PMID:22536116
Two independent mechanisms promote expression of an N-terminal truncated USP18 isoform with higher DeISGylation activity in the nucleus. PMID:22170061
Complete genome sequence of an Argentinean isolate of Solenopsis invicta virus 3. PMID:20033838
CUG start codon generates thioredoxin/glutathione reductase isoforms in mouse testes. PMID:20018845
IRSS: a web-based tool for automatic layout and analysis of IRES secondary structure prediction and searching system in silico. PMID:19473520
VARNA: Interactive drawing and editing of the RNA secondary structure. PMID:19398448
Cap-independent translation of human SP-A 5'-UTR variants: a double-loop structure and cis-element contribution. PMID:19181744
Transterm: a database to aid the analysis of regulatory sequences in mRNAs. PMID:18984623
Rfam: updates to the RNA families database. PMID:18953034
Firefly luciferase gene contains a cryptic promoter. PMID:18697919
Hypoxia-mediated selective mRNA translation by an internal ribosome entry site-independent mechanism. PMID:18430730
Translational control of retroviruses. PMID:17224922
Searching for IRES. PMID:16957278 - http://dx.doi.org/10.1093/nar/gkp981
Tags:
Tags
More detailed information about this field from each metasource.
biological regulation
metasource: Fairsharing.org
version: FAIRsharing.org: IRESite; IRESite; DOI: https://doi.org/10.25504/FAIRsharing.kd39j4; Last edited: Jan. 8, 2019, 1:16 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
nucleic acid sequence
metasource: Fairsharing.org
version: FAIRsharing.org: IRESite; IRESite; DOI: https://doi.org/10.25504/FAIRsharing.kd39j4; Last edited: Jan. 8, 2019, 1:16 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
peptide
metasource: Fairsharing.org
version: FAIRsharing.org: IRESite; IRESite; DOI: https://doi.org/10.25504/FAIRsharing.kd39j4; Last edited: Jan. 8, 2019, 1:16 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
plasmid
metasource: Fairsharing.org
version: FAIRsharing.org: IRESite; IRESite; DOI: https://doi.org/10.25504/FAIRsharing.kd39j4; Last edited: Jan. 8, 2019, 1:16 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
ribonucleic acid
metasource: Fairsharing.org
version: FAIRsharing.org: IRESite; IRESite; DOI: https://doi.org/10.25504/FAIRsharing.kd39j4; Last edited: Jan. 8, 2019, 1:16 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
ribosomal rna
metasource: Fairsharing.org
version: FAIRsharing.org: IRESite; IRESite; DOI: https://doi.org/10.25504/FAIRsharing.kd39j4; Last edited: Jan. 8, 2019, 1:16 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
rna sequence databases
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657
rna
metasource: bio.tools
version: extracted_at: 2022-11-04T11:26:21.276445
structural biology
metasource: bio.tools
version: extracted_at: 2022-11-04T11:26:21.276445
sequence sites, features and motifs
metasource: bio.tools
version: extracted_at: 2022-11-04T11:26:21.276445
Tags
More detailed information about this field from each metasource.
biological regulation
metasource: Fairsharing.orgversion: FAIRsharing.org: IRESite; IRESite; DOI: https://doi.org/10.25504/FAIRsharing.kd39j4; Last edited: Jan. 8, 2019, 1:16 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
nucleic acid sequence
metasource: Fairsharing.orgversion: FAIRsharing.org: IRESite; IRESite; DOI: https://doi.org/10.25504/FAIRsharing.kd39j4; Last edited: Jan. 8, 2019, 1:16 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
peptide
metasource: Fairsharing.orgversion: FAIRsharing.org: IRESite; IRESite; DOI: https://doi.org/10.25504/FAIRsharing.kd39j4; Last edited: Jan. 8, 2019, 1:16 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
plasmid
metasource: Fairsharing.orgversion: FAIRsharing.org: IRESite; IRESite; DOI: https://doi.org/10.25504/FAIRsharing.kd39j4; Last edited: Jan. 8, 2019, 1:16 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
ribonucleic acid
metasource: Fairsharing.orgversion: FAIRsharing.org: IRESite; IRESite; DOI: https://doi.org/10.25504/FAIRsharing.kd39j4; Last edited: Jan. 8, 2019, 1:16 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
ribosomal rna
metasource: Fairsharing.orgversion: FAIRsharing.org: IRESite; IRESite; DOI: https://doi.org/10.25504/FAIRsharing.kd39j4; Last edited: Jan. 8, 2019, 1:16 p.m.; Last accessed: Jan 03 2022 7:07 p.m.
rna sequence databases
metasource: Nucleic Acid Research database catalogueversion: extracted_at: 2022-11-04T11:16:25.468657
rna
metasource: bio.toolsversion: extracted_at: 2022-11-04T11:26:21.276445
structural biology
metasource: bio.toolsversion: extracted_at: 2022-11-04T11:26:21.276445
sequence sites, features and motifs
metasource: bio.toolsversion: extracted_at: 2022-11-04T11:26:21.276445
biological regulation nucleic acid sequence peptide plasmid rna ribosomal rna rna sequence rna structural biology sequence sites, features and motifs
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