D3DistalMutation is a database to explore the effect of distal mutations on enzyme activity. In general, D3DistalMutation describes the effect of distal mutation (mutations more than 10 Å away from the active site) on enzyme activity and classified enzymes into four classes, viz., no activity change, decrease activity, loss of activity and increase activity. The D3DistalMutation provides information including mutation residues, active sites, the closest distances, activity change description and references.
protein binding sites enzyme genetic variation