CellPhoneDB
CellPhoneDB is a publicly available repository of curated receptors, ligands and their interactions. Subunit architecture is included for both ligands and receptors, representing heteromeric complexes accurately. This is crucial, as cell-cell communication relies on multi-subunit protein complexes that go beyond the binary representation used in most databases and studies.
Description
More detailed information about this field from each metasource.
CellPhoneDB is a publicly available repository of curated receptors, ligands and their interactions. Subunit architecture is included for both ligands and receptors, representing heteromeric complexes accurately. This is crucial, as cell-cell communication relies on multi-subunit protein complexes that go beyond the binary representation used in most databases and studies.
metasource: bio.toolsversion: extracted_at: 2022-11-04T11:28:34.753500
Webpage:
http://www.CellPhoneDB.orgWebpage
More detailed information about this field from each metasource.
Licence:
Name: MITLicence name
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Publications:
Publications
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CellPhoneDB: inferring cell-cell communication from combined expression of multi-subunit ligand-receptor complexes
PMID: 32103204
metasource: bio.tools
version: extracted_at: 2022-11-04T11:28:34.753500
Publications
More detailed information about this field from each metasource.
CellPhoneDB: inferring cell-cell communication from combined expression of multi-subunit ligand-receptor complexes
PMID: 32103204
metasource: bio.tools
version: extracted_at: 2022-11-04T11:28:34.753500
-
CellPhoneDB: inferring cell-cell communication from combined expression of multi-subunit ligand-receptor complexes
PubMed citations: 320.
320 articles citing: CellPhoneDB: inferring cell-cell communication from combined expression of multi-subunit ligand-receptor complexes
Single-cell Atlas of common variable immunodeficiency shows germinal center-associated epigenetic dysregulation in B-cell responses. PMID:35365635
Integrated Analysis Highlights the Immunosuppressive Role of TREM2+ Macrophages in Hepatocellular Carcinoma. PMID:35359989
Uncovering Pharmacological Opportunities for Cancer Stem Cells-A Systems Biology View. PMID:35359437
Coupling of angiogenesis and odontogenesis orchestrates tooth mineralization in mice. PMID:35319724
StemSC: a cross-dataset human stemness index for single-cell samples. PMID:35313979
Reconstructing codependent cellular cross-talk in lung adenocarcinoma using REMI. PMID:35302849
Single-Cell Transcriptomics Identifies Heterogeneity of Mouse Mammary Gland Fibroblasts With Distinct Functions, Estrogen Responses, Differentiation Processes, and Crosstalks With Epithelium. PMID:35300413
A single-cell atlas of human and mouse white adipose tissue. PMID:35296864
A multidimensional coding architecture of the vagal interoceptive system. PMID:35296859
Recent Advances in Models of Immune-Mediated Drug-Induced Liver Injury. PMID:35295156
The role of cell geometry and cell-cell communication in gradient sensing. PMID:35286298
Cell-Cell Communication Alterations via Intercellular Signaling Pathways in Substantia Nigra of Parkinson's Disease. PMID:35283752
Spatially Annotated Single Cell Sequencing for Unraveling Intratumor Heterogeneity. PMID:35273957
Deciphering tissue structure and function using spatial transcriptomics. PMID:35273328
Computation and visualization of cell-cell signaling topologies in single-cell systems data using Connectome. PMID:35264704
TraSig: inferring cell-cell interactions from pseudotime ordering of scRNA-Seq data. PMID:35255944
Tertiary lymphoid structure and decreased CD8+ T cell infiltration in minimally invasive adenocarcinoma. PMID:35243243
Single-cell transcriptomics links malignant T cells to the tumor immune landscape in cutaneous T cell lymphoma. PMID:35241665
Single-Cell Sequencing Technologies in Precision Oncology. PMID:35230694
Identification of kidney injury released circulating osteopontin as causal agent of respiratory failure. PMID:35213222
Single-Cell Sequencing Reveals an Intrinsic Heterogeneity of the Preovulatory Follicular Microenvironment. PMID:35204732
Cellular Phenotypic Transformation in Heart Failure Caused by Coronary Heart Disease and Dilated Cardiomyopathy: Delineating at Single-Cell Level. PMID:35203611
The Neuronal Transcription Factor Creb3l1 Potential Upregulates Ntrk2 in the Hypertensive Microenvironment to Promote Vascular Smooth Muscle Cell-Neuron Interaction and Prevent Neurons from Ferroptosis: A Bioinformatic Research of scRNA-seq Data. PMID:35186168
Identification of Synovial Fibroblast-Associated Neuropeptide Genes and m6A Factors in Rheumatoid Arthritis Using Single-Cell Analysis and Machine Learning. PMID:35186167
Single-Cell Transcriptomic and Epigenetic Analyses of Mouse Mammary Development Starting with the Embryo. PMID:35175591
Urine Single-Cell RNA Sequencing in Focal Segmental Glomerulosclerosis Reveals Inflammatory Signatures. PMID:35155868
Three-dimensional spatial transcriptomics uncovers cell type localizations in the human rheumatoid arthritis synovium. PMID:35149753
Single-cell analysis of human glioma and immune cells identifies S100A4 as an immunotherapy target. PMID:35140215
Lymphocyte infiltration and thyrocyte destruction are driven by stromal and immune cell components in Hashimoto's thyroiditis. PMID:35140214
Single-cell transcriptomic analysis of human colonic macrophages reveals niche-specific subsets. PMID:35139155
Temporal analyses of postnatal liver development and maturation by single-cell transcriptomics. PMID:35134346
RNA sequencing on muscle biopsy from a 5-week bed rest study reveals the effect of exercise and potential interactions with dorsal root ganglion neurons. PMID:35133080
Spatial components of molecular tissue biology. PMID:35132261
Single-cell RNA sequencing identifies an Il1rn+/Trem1+ macrophage subpopulation as a cellular target for mitigating the progression of thoracic aortic aneurysm and dissection. PMID:35132073
Selective multi-kinase inhibition sensitizes mesenchymal pancreatic cancer to immune checkpoint blockade by remodeling the tumor microenvironment. PMID:35122074
The Cancer Surfaceome Atlas integrates genomic, functional and drug response data to identify actionable targets. PMID:35121907
High Throughput scRNA-Seq Provides Insights Into Leydig Cell Senescence Induced by Experimental Autoimmune Orchitis: A Prominent Role of Interstitial Fibrosis and Complement Activation. PMID:35111154
Single-Cell Transcriptome Analysis of Chronic Antibody-Mediated Rejection After Renal Transplantation. PMID:35111153
Squidpy: a scalable framework for spatial omics analysis. PMID:35102346
Temporal modelling using single-cell transcriptomics. PMID:35102309
Tailoring Cardiac Synthetic Transcriptional Modulation Towards Precision Medicine. PMID:35097003
Identification of a unique tumor cell subset employing myeloid transcriptional circuits to create an immunomodulatory microenvironment in glioblastoma. PMID:35096487
Dissecting the heterogeneity of the microenvironment in primary and recurrent nasopharyngeal carcinomas using single-cell RNA sequencing. PMID:35096485
Single-cell RNA sequencing to track novel perspectives in HSC heterogeneity. PMID:35093185
The Crosstalk Between Malignant Cells and Tumor-Promoting Immune Cells Relevant to Immunotherapy in Pancreatic Ductal Adenocarcinoma. PMID:35087839
Single-Cell Profiles of Age-Related Osteoarthritis Uncover Underlying Heterogeneity Associated With Disease Progression. PMID:35083277
Back to the Future: Spatiotemporal Determinants of NK Cell Antitumor Function. PMID:35082797
New horizons in the stormy sea of multimodal single-cell data integration. PMID:35063095
An atlas of dynamic peripheral blood mononuclear cell landscapes in human perioperative anaesthesia/surgery. PMID:35061932
Coal dust exposure triggers heterogeneity of transcriptional profiles in mouse pneumoconiosis and Vitamin D remedies. PMID:35057792
Towards Tabula Gallus. PMID:35054796
Spatial omics: Navigating to the golden era of cancer research. PMID:35040595
SARS-CoV-2 infects the human kidney and drives fibrosis in kidney organoids. PMID:35032430
Integrated single-cell RNA sequencing analysis reveals distinct cellular and transcriptional modules associated with survival in lung cancer. PMID:35027529
Aging-related cell type-specific pathophysiologic immune responses that exacerbate disease severity in aged COVID-19 patients. PMID:35023286
The use of machine learning to discover regulatory networks controlling biological systems. PMID:35016036
Obesity modulates cell-cell interactions during ovarian folliculogenesis. PMID:35005562
Single-Cell Analysis Identify Transcription Factor BACH1 as a Master Regulator Gene in Vascular Cells During Aging. PMID:35004685
Single-Cell RNA Sequencing Reveals CXCLs Enriched Fibroblasts Within Odontogenic Keratocysts. PMID:34992422
Single-cell RNA sequencing reveals a pro-invasive cancer-associated fibroblast subgroup associated with poor clinical outcomes in patients with gastric cancer. PMID:34976204
Single-Cell Transcriptomic Analysis Reveals Developmental Relationships and Specific Markers of Mouse Periodontium Cellular Subsets. PMID:34966906
A Meta-Analysis of Human Transcriptomics Data in the Context of Peritoneal Dialysis Identifies Novel Receptor-Ligand Interactions as Potential Therapeutic Targets. PMID:34948074
Multifunctional barcoding with ClonMapper enables high-resolution study of clonal dynamics during tumor evolution and treatment. PMID:34939038
Resolving the immune landscape of human prostate at a single-cell level in health and cancer. PMID:34936871
Targeting uPA-uPAR interaction to improve intestinal epithelial barrier integrity in inflammatory bowel disease. PMID:34933179
Heterocellular OSM-OSMR signalling reprograms fibroblasts to promote pancreatic cancer growth and metastasis. PMID:34921158
Comprehensive analysis of spatial architecture in primary liver cancer. PMID:34919432
Single-cell RNA sequencing infers the role of malignant cells in drug-resistant multiple myeloma. PMID:34918874
Deciphering functional tumor states at single-cell resolution. PMID:34918370
Single-Cell RNA Sequencing Analysis of the Heterogeneity in Gene Regulatory Networks in Colorectal Cancer. PMID:34917613
Single-cell transcriptome analysis identifies a unique tumor cell type producing multiple hormones in ectopic ACTH and CRH secreting pheochromocytoma. PMID:34905486
Dissecting the single-cell transcriptomeunderlying chronic liver injury. PMID:34900395
Clinical Response to Anti-CD47 Immunotherapy Is Associated with Rapid Reduction of Exhausted Bystander CD4+ BTLA+ T Cells in Tumor Microenvironment of Mycosis Fungoides. PMID:34885092
Single-cell analysis identifies a key role for Hhip in murine coronal suture development. PMID:34880220
A single-cell transcriptomic landscape of the lungs of patients with COVID-19. PMID:34876692
Mapping the temporal and spatial dynamics of the human endometrium in vivo and in vitro. PMID:34857954
Subclone-specific microenvironmental impact and drug response in refractory multiple myeloma revealed by single-cell transcriptomics. PMID:34845188
Multidimensional Single-Nuclei RNA-Seq Reconstruction of Adipose Tissue Reveals Adipocyte Plasticity Underlying Thermogenic Response. PMID:34831295
Updates on Immunotherapy and Immune Landscape in Renal Clear Cell Carcinoma. PMID:34831009
Special Issue "Microglia Heterogeneity and Its Relevance for Translational Research". PMID:34830232
Single-Cell Transcriptome Profiling Reveals Multicellular Ecosystem of Nucleus Pulposus during Degeneration Progression. PMID:34825784
Interrogation of the microenvironmental landscape in spinal ependymomas reveals dual functions of tumor-associated macrophages. PMID:34824203
Establishment of a prognosis Prediction Model Based on Pyroptosis-Related Signatures Associated With the Immune Microenvironment and Molecular Heterogeneity in Clear Cell Renal Cell Carcinoma. PMID:34804944
Application of single-cell RNA sequencing technology in liver diseases: a narrative review. PMID:34790804
Single-cell transcriptomic characterization of a gastrulating human embryo. PMID:34789876
Intraocular dendritic cells characterize HLA-B27-associated acute anterior uveitis. PMID:34783307
Intertwined Signaling Pathways Governing Tooth Development: A Give-and-Take Between Canonical Wnt and Shh. PMID:34778267
Maximizing the Utility of Transcriptomics Data in Inflammatory Skin Diseases. PMID:34777377
Single-Cell Transcriptomics Analysis of Human Small Antral Follicles. PMID:34769386
Single-cell analysis of human non-small cell lung cancer lesions refines tumor classification and patient stratification. PMID:34767762
Deciphering cell lineage specification of human lung adenocarcinoma with single-cell RNA sequencing. PMID:34764257
Besca, a single-cell transcriptomics analysis toolkit to accelerate translational research. PMID:34761219
ImmReg: the regulon atlas of immune-related pathways across cancer types. PMID:34755873
Network Biology Approaches to Achieve Precision Medicine in Inflammatory Bowel Disease. PMID:34745229
Single-Cell Integration Analysis of Heterotopic Ossification and Fibrocartilage Developmental Lineage: Endoplasmic Reticulum Stress Effector Xbp1 Transcriptionally Regulates the Notch Signaling Pathway to Mediate Fibrocartilage Differentiation. PMID:34737845
Integrated Single-Cell Bioinformatics Analysis Reveals Intrinsic and Extrinsic Biological Characteristics of Hematopoietic Stem Cell Aging. PMID:34737765
Identification of the distinctive role of DPT in dilated cardiomyopathy: a study based on bulk and single-cell transcriptomic analysis. PMID:34733953
Macrophages orchestrate the expansion of a proangiogenic perivascular niche during cancer progression. PMID:34730997
Systems biological assessment of altered cytokine responses to bacteria and fungi reveals impaired immune functionality in schizophrenia. PMID:34728799
Human prostate cancer bone metastases have an actionable immunosuppressive microenvironment. PMID:34719426
Mesenchymal Stromal Cells as a Cellular Target in Myeloid Malignancy: Chances and Challenges in the Genome Editing of Stromal Alterations. PMID:34713241
Transcriptomics of the depressed and PTSD brain. PMID:34703849
Exploring the oncostatin M (OSM) feed-forward signaling of glioblastoma via STAT3 in pan-cancer analysis. PMID:34702277
Cell-Cell Communication Networks in Tissue: Toward Quantitatively Linking Structure with Function. PMID:34693081
Aortic heterogeneity across segments and under high fat/salt/glucose conditions at the single-cell level. PMID:34692110
Making Blood from the Vessel: Extrinsic and Environmental Cues Guiding the Endothelial-to-Hematopoietic Transition. PMID:34685398
Characterizing Intercellular Communication of Pan-Cancer Reveals SPP1+ Tumor-Associated Macrophage Expanded in Hypoxia and Promoting Cancer Malignancy Through Single-Cell RNA-Seq Data. PMID:34676217
Analysis of Cellular Heterogeneity in Immune Microenvironment of Primary Central Nervous System Lymphoma by Single-Cell Sequencing. PMID:34671548
Single-cell RNA sequencing reveals distinct tumor microenvironmental patterns in lung adenocarcinoma. PMID:34663877
Single-cell transcriptomic analysis of the tumor ecosystems underlying initiation and progression of papillary thyroid carcinoma. PMID:34663816
Dysregulation of TFH-B-TRM lymphocyte cooperation is associated with unfavorable anti-PD-1 responses in EGFR-mutant lung cancer. PMID:34663810
Forecasting cellular states: from descriptive to predictive biology via single-cell multiomics. PMID:34660940
Insights From Single Cell RNA Sequencing Into the Immunology of Type 1 Diabetes- Cell Phenotypes and Antigen Specificity. PMID:34659258
Signatures of plasticity, metastasis, and immunosuppression in an atlas of human small cell lung cancer. PMID:34653364
Single Cell RNA-Sequencing Reveals a Murine Gallbladder Cell Transcriptome Atlas During the Process of Cholesterol Gallstone Formation. PMID:34650971
Inherent hepatocytic heterogeneity determines expression and retention of edited F9 alleles post-AAV/CRISPR infusion. PMID:34649996
CancerSCEM: a database of single-cell expression map across various human cancers. PMID:34643725
Single-Cell RNA Sequencing (scRNA-seq) in Cardiac Tissue: Applications and Limitations. PMID:34629873
Single-cell RNA-seq unravels alterations of the human spermatogonial stem cell compartment in patients with impaired spermatogenesis. PMID:34622232
Molecular and Cellular Dynamics of Aortic Aneurysms Revealed by Single-Cell Transcriptomics. PMID:34615376
Single-cell analysis reveals dynamic changes of neural cells in developing human spinal cord. PMID:34605607
Tumor-Infiltrating PD-1hiCD8+-T-Cell Signature as an Effective Biomarker for Immune Checkpoint Inhibitor Therapy Response Across Multiple Cancers. PMID:34604032
A single-cell interactome of human tooth germ from growing third molar elucidates signaling networks regulating dental development. PMID:34600587
Immune Cell Landscape of Patients With Diabetic Macular Edema by Single-Cell RNA Analysis. PMID:34594230
A cell-type-specific atlas of the inner ear transcriptional response to acoustic trauma. PMID:34592158
Single-cell RNA sequencing reveals markers of disease progression in primary cutaneous T-cell lymphoma. PMID:34583709
Single-Cell RNA Sequencing Identifies New Inflammation-Promoting Cell Subsets in Asian Patients With Chronic Periodontitis. PMID:34566966
Synovial single-cell heterogeneity, zonation and interactions: a patchwork of effectors in arthritis. PMID:34559213
Deciphering mouse uterine receptivity for embryo implantation at single-cell resolution. PMID:34558134
High-dimensional profiling reveals phenotypic heterogeneity and disease-specific alterations of granulocytes in COVID-19. PMID:34548411
Single-Cell Transcriptome Sequencing and Proteomics Reveal Neonatal Ileum Dynamic Developmental Potentials. PMID:34546071
Cooperation between melanoma cell states promotes metastasis through heterotypic cluster formation. PMID:34529939
Single-Cell RNA Sequencing Reveals the Migration of Osteoclasts in Giant Cell Tumor of Bone. PMID:34504794
LR Hunting: A Random Forest Based Cell-Cell Interaction Discovery Method for Single-Cell Gene Expression Data. PMID:34497635
A Novel Intercellular Communication-Associated Gene Signature for Prognostic Prediction and Clinical Value in Patients With Lung Adenocarcinoma. PMID:34497634
Cells of the human intestinal tract mapped across space and time. PMID:34497389
Multiplexed single-cell analysis of organoid signaling networks. PMID:34497385
Tumor-initiating stem cell shapes its microenvironment into an immunosuppressive barrier and pro-tumorigenic niche. PMID:34496236
A single-cell and spatially resolved atlas of human breast cancers. PMID:34493872
A single-cell atlas of liver metastases of colorectal cancer reveals reprogramming of the tumor microenvironment in response to preoperative chemotherapy. PMID:34489408
Modelling the impact of decidual senescence on embryo implantation in human endometrial assembloids. PMID:34487490
Aging, inflammation and DNA damage in the somatic testicular niche with idiopathic germ cell aplasia. PMID:34471128
Single-cell transcriptomes reveal heterogeneity of high-grade serous ovarian carcinoma. PMID:34459128
Roles of the Immune/Methylation/Autophagy Landscape on Single-Cell Genotypes and Stroke Risk in Breast Cancer Microenvironment. PMID:34457116
Regulatory T cells promote innate inflammation after skin barrier breach via TGF-β activation. PMID:34452925
Clinical Perspectives of Single-Cell RNA Sequencing. PMID:34439827
Interpretable systems biomarkers predict response to immune-checkpoint inhibitors. PMID:34430923
Elucidation of Tumor-Stromal Heterogeneity and the Ligand-Receptor Interactome by Single-Cell Transcriptomics in Real-world Pancreatic Cancer Biopsies. PMID:34426439
Single-cell sequencing of immune cells from anticitrullinated peptide antibody positive and negative rheumatoid arthritis. PMID:34404786
Exploring tissue architecture using spatial transcriptomics. PMID:34381231
Oncostatin M Receptor-Targeted Antibodies Suppress STAT3 Signaling and Inhibit Ovarian Cancer Growth. PMID:34380633
The developing mouse coronal suture at single-cell resolution. PMID:34376651
Hedgehog interacting protein-expressing lung fibroblasts suppress lymphocytic inflammation in mice. PMID:34375314
Integrated single-cell analysis revealed immune dynamics during Ad5-nCoV immunization. PMID:34373443
TIPS: trajectory inference of pathway significance through pseudotime comparison for functional assessment of single-cell RNAseq data. PMID:34370020
Single-Cell Transcriptomics Reveals the Complexity of the Tumor Microenvironment of Treatment-Naive Osteosarcoma. PMID:34367994
Single-Cell RNA Sequencing Reveals the Immunological Profiles of Renal Allograft Rejection in Mice. PMID:34367152
Regulatory Macrophages and Tolerogenic Dendritic Cells in Myeloid Regulatory Cell-Based Therapies. PMID:34360736
TNFR2 Signaling Regulates the Immunomodulatory Function of Oligodendrocyte Precursor Cells. PMID:34359956
Unveiling the Pathogenesis of Psychiatric Disorders Using Network Models. PMID:34356117
Computational reconstruction of the signalling networks surrounding implanted biomaterials from single-cell transcriptomics. PMID:34341534
Identification of HSC/MPP expansion units in fetal liver by single-cell spatiotemporal transcriptomics. PMID:34341490
CellCall: integrating paired ligand-receptor and transcription factor activities for cell-cell communication. PMID:34331449
Multimodal single-cell omics analysis identifies epithelium-immune cell interactions and immune vulnerability associated with sex differences in COVID-19. PMID:34330889
From bench to bedside: Single-cell analysis for cancer immunotherapy. PMID:34329587
Single-cell transcriptomics reveals heterogeneous progression and EGFR activation in pancreatic adenosquamous carcinoma. PMID:34326696
SARS-CoV-2 activates lung epithelial cell proinflammatory signaling and leads to immune dysregulation in COVID-19 patients. PMID:34311326
Statistical and machine learning methods for spatially resolved transcriptomics with histology. PMID:34285782
Intrathecal activation of CD8+ memory T cells in IgG4-related disease of the brain parenchyma. PMID:34254741
Single-cell RNA sequencing reveals distinct cellular factors for response to immunotherapy targeting CD73 and PD-1 in colorectal cancer. PMID:34253638
IDH Mutation Subgroup Status Associates with Intratumor Heterogeneity and the Tumor Microenvironment in Intrahepatic Cholangiocarcinoma. PMID:34250753
High-grade serous tubo-ovarian cancer refined with single-cell RNA sequencing: specific cell subtypes influence survival and determine molecular subtype classification. PMID:34238352
How Do Uterine Natural Killer and Innate Lymphoid Cells Contribute to Successful Pregnancy? PMID:34234770
Tumor-Infiltrating B Lymphocyte Profiling Identifies IgG-Biased, Clonally Expanded Prognostic Phenotypes in Triple-Negative Breast Cancer. PMID:34224371
Ligand-Receptor Interactions Elucidate Sex-Specific Pathways in the Trajectory From Primordial Germ Cells to Gonia During Human Development. PMID:34222234
Applications and analytical tools of cell communication based on ligand-receptor interactions at single cell level. PMID:34217372
The predicting roles of carcinoembryonic antigen and its underlying mechanism in the progression of coronavirus disease 2019. PMID:34217339
Single-Cell Transcriptional Heterogeneity of Lymphatic Endothelial Cells in Normal and Inflamed Murine Lymph Nodes. PMID:34199492
Single-cell analyses reveal suppressive tumor microenvironment of human colorectal cancer. PMID:34185431
Diversity and intratumoral heterogeneity in human gallbladder cancer progression revealed by single-cell RNA sequencing. PMID:34185421
Spatial transcriptome profiling by MERFISH reveals fetal liver hematopoietic stem cell niche architecture. PMID:34183665
The endogenous cellular protease inhibitor SPINT2 controls SARS-CoV-2 viral infection and is associated to disease severity. PMID:34181691
Multi-Omics Approaches in Immunological Research. PMID:34177908
Single-cell analysis of mouse and human prostate reveals novel fibroblasts with specialized distribution and microenvironment interactions. PMID:34173975
Single-cell RNA-seq reveals transcriptional landscape and intratumor heterogenicity in gallbladder cancer liver metastasis microenvironment. PMID:34164523
Single-cell transcriptomics defines heterogeneity of epicardial cells and fibroblasts within the infarcted murine heart. PMID:34152268
Integrating single-cell and spatial transcriptomics to elucidate intercellular tissue dynamics. PMID:34145435
Single-cell RNA-seq reveals fibroblast heterogeneity and increased mesenchymal fibroblasts in human fibrotic skin diseases. PMID:34140509
Machine Intelligence in Single-Cell Data Analysis: Advances and New Challenges. PMID:34135939
The role of single-cell sequencing in studying tumour evolution. PMID:34131659
Single-cell biology to decode the immune cellular composition of kidney inflammation. PMID:34125286
Applications of single-cell sequencing in cancer research: progress and perspectives. PMID:34108022
Resolving the graft ischemia-reperfusion injury during liver transplantation at the single cell resolution. PMID:34103479
Spatio-temporal mRNA tracking in the early zebrafish embryo. PMID:34099733
An integrative microenvironment approach for laryngeal carcinoma: the role of immune/methylation/autophagy signatures on disease clinical prognosis and single-cell genotypes. PMID:34093817
Recent Advances in Single-Cell Profiling and Multispecific Therapeutics: Paving the Way for a New Era of Precision Medicine Targeting Cardiac Fibroblasts. PMID:34081224
Cell-Cell Communication at the Embryo Implantation Site of Mouse Uterus Revealed by Single-Cell Analysis. PMID:34068395
Stromal Heterogeneity in the Human Proliferative Endometrium-A Single-Cell RNA Sequencing Study. PMID:34067358
Understanding the Adult Mammalian Heart at Single-Cell RNA-Seq Resolution. PMID:34055776
Single-nucleus transcriptomic landscape of primate hippocampal aging. PMID:34052996
Transcriptomic Profiling of Human Placenta in Gestational Diabetes Mellitus at the Single-Cell Level. PMID:34025588
Charting human development using a multi-endodermal organ atlas and organoid models. PMID:34019796
The multiple myeloma microenvironment is defined by an inflammatory stromal cell landscape. PMID:34017122
Single-cell co-expression analysis reveals that transcriptional modules are shared across cell types in the brain. PMID:34015329
Islet β-cells physiological difference study of old and young mice based on single-cell transcriptomics. PMID:34003589
Multi-omic profiling of lung and liver tumor microenvironments of metastatic pancreatic cancer reveals site-specific immune regulatory pathways. PMID:33985562
scConnect: a method for exploratory analysis of cell-cell communication based on single cell RNA sequencing data. PMID:33974001
The liver metastatic niche: modelling the extracellular matrix in metastasis. PMID:33973625
Maternal respiratory SARS-CoV-2 infection in pregnancy is associated with a robust inflammatory response at the maternal-fetal interface. PMID:33969332
Divergent and self-reactive immune responses in the CNS of COVID-19 patients with neurological symptoms. PMID:33969321
Longitudinal proteomic analysis of severe COVID-19 reveals survival-associated signatures, tissue-specific cell death, and cell-cell interactions. PMID:33969320
The landscape of cell-cell communication through single-cell transcriptomics. PMID:33969247
Single-Nucleus Transcriptomic Analysis Reveals Important Cell Cross-Talk in Diabetic Kidney Disease. PMID:33968963
A single-cell map of intratumoral changes during anti-PD1 treatment of patients with breast cancer. PMID:33958794
Single-cell analysis reveals urothelial cell heterogeneity and regenerative cues following cyclophosphamide-induced bladder injury. PMID:33953164
A cellular and spatial map of the choroid plexus across brain ventricles and ages. PMID:33932339
A molecular single-cell lung atlas of lethal COVID-19. PMID:33915568
Fibroblasts as immune regulators in infection, inflammation and cancer. PMID:33911232
Single-cell sequencing of human white adipose tissue identifies new cell states in health and obesity. PMID:33907320
Tumor restriction by type I collagen opposes tumor-promoting effects of cancer-associated fibroblasts. PMID:33905375
Rapid Identification of Druggable Targets and the Power of the PHENotype SIMulator for Effective Drug Repurposing in COVID-19. PMID:33880466
Mucosal-associated invariant T cell responses differ by sex in COVID-19. PMID:33870241
Investigating Mechanisms of Response or Resistance to Immune Checkpoint Inhibitors by Analyzing Cell-Cell Communications in Tumors Before and After Programmed Cell Death-1 (PD-1) Targeted Therapy: An Integrative Analysis Using Single-cell RNA and Bulk-RNA Sequencing Data. PMID:33868792
A single cell atlas of human cornea that defines its development, limbal progenitor cells and their interactions with the immune cells. PMID:33865984
Single-cell sequencing links multiregional immune landscapes and tissue-resident T cells in ccRCC to tumor topology and therapy efficacy. PMID:33861994
Single-cell transcriptomic profiling provides insights into the toxic effects of Zearalenone exposure on primordial follicle assembly. PMID:33859742
Unlocking immune-mediated disease mechanisms with transcriptomics. PMID:33843974
Single Cell Transcriptome Data Analysis Defines the Heterogeneity of Peripheral Nerve Cells in Homeostasis and Regeneration. PMID:33828460
Single-Cell RNA-seq Reveals Characteristics of Malignant Cells and Immune Microenvironment in Subcutaneous Panniculitis-Like T-Cell Lymphoma. PMID:33816243
Connecting the Dots: Resolving the Bone Marrow Niche Heterogeneity. PMID:33777933
Single-cell transcriptomics dissects hematopoietic cell destruction and T-cell engagement in aplastic anemia. PMID:33763704
High-resolution epigenome analysis in nasal samples derived from children with respiratory viral infections reveals striking changes upon SARS-CoV-2 infection. PMID:33758880
Comprehensive single-cell sequencing reveals the stromal dynamics and tumor-specific characteristics in the microenvironment of nasopharyngeal carcinoma. PMID:33750785
Integrated intra- and intercellular signaling knowledge for multicellular omics analysis. PMID:33749993
Haematopoietic ageing through the lens of single-cell technologies. PMID:33735102
Single-cell analysis can define distinct evolution of tumor sites in follicular lymphoma. PMID:33728464
Mapping the immune microenvironment for mandibular alveolar bone homeostasis at single-cell resolution. PMID:33723232
Progressive immune dysfunction with advancing disease stage in renal cell carcinoma. PMID:33711273
Tumor and immune reprogramming during immunotherapy in advanced renal cell carcinoma. PMID:33711272
Time-resolved single-cell analysis of Brca1 associated mammary tumourigenesis reveals aberrant differentiation of luminal progenitors. PMID:33686070
Single-cell meta-analysis of SARS-CoV-2 entry genes across tissues and demographics. PMID:33654293
Intercellular Interactions of an Adipogenic CXCL12-Expressing Stromal Cell Subset in Murine Bone Marrow. PMID:33651379
Application of Single-Cell Approaches to Study Myeloproliferative Neoplasm Biology. PMID:33641869
Understanding cell-cell communication and signaling in the colorectal cancer microenvironment. PMID:33635003
System Genetics Including Causal Inference Identify Immune Targets for Coronary Artery Disease and the Lifespan. PMID:33625251
Clonal expansion and activation of tissue-resident memory-like Th17 cells expressing GM-CSF in the lungs of severe COVID-19 patients. PMID:33622974
iMAP: integration of multiple single-cell datasets by adversarial paired transfer networks. PMID:33602306
Tumor-infiltrating dendritic cell states are conserved across solid human cancers. PMID:33601412
Dissection of intercellular communication using the transcriptome-based framework ICELLNET. PMID:33597528
Inference and analysis of cell-cell communication using CellChat. PMID:33597522
Next Generation Imaging Techniques to Define Immune Topographies in Solid Tumors. PMID:33584676
Single-cell RNA-seq dissects the intratumoral heterogeneity of triple-negative breast cancer based on gene regulatory networks. PMID:33575114
Single-cell transcriptomes of peripheral blood cells indicate and elucidate severity of COVID-19. PMID:33564978
Microglia and Central Nervous System-Associated Macrophages-From Origin to Disease Modulation. PMID:33556248
Stromal-immune cell crosstalk fundamentally alters the lung microenvironment following tissue insult. PMID:33556186
Engineered Tools to Study Intercellular Communication. PMID:33552865
SARS-CoV-2 infection in pregnancy is associated with robust inflammatory response at the maternal-fetal interface. PMID:33532791
Cross-species single-cell transcriptomic analysis reveals pre-gastrulation developmental differences among pigs, monkeys, and humans. PMID:33531465
Discriminating mild from critical COVID-19 by innate and adaptive immune single-cell profiling of bronchoalveolar lavages. PMID:33473155
Cellinker: a platform of ligand-receptor interactions for intercellular communication analysis. PMID:33471060
The orchestrated cellular and molecular responses of the kidney to endotoxin define a precise sepsis timeline. PMID:33448928
Regulation of immune responses by the airway epithelial cell landscape. PMID:33442032
Single-cell transcriptome analysis revealed the heterogeneity and microenvironment of gastrointestinal stromal tumors. PMID:33393143
Understanding the unimodal distributions of cancer occurrence rates: it takes two factors for a cancer to occur. PMID:33377150
Hypertension delays viral clearance and exacerbates airway hyperinflammation in patients with COVID-19. PMID:33361824
Single-Cell Transcriptional Survey of Ileal-Anal Pouch Immune Cells From Ulcerative Colitis Patients. PMID:33359089
Integrative Single-Cell RNA-Seq and ATAC-Seq Analysis of Human Developmental Hematopoiesis. PMID:33352111
Inferring microenvironmental regulation of gene expression from single-cell RNA sequencing data using scMLnet with an application to COVID-19. PMID:33341869
Exploring Additional Valuable Information From Single-Cell RNA-Seq Data. PMID:33335900
Harnessing Single-Cell RNA Sequencing to Better Understand How Diseased Cells Behave the Way They Do in Cardiovascular Disease. PMID:33327741
Distinct populations of crypt-associated fibroblasts act as signaling hubs to control colon homeostasis. PMID:33306673
Heterogeneous bone-marrow stromal progenitors drive myelofibrosis via a druggable alarmin axis. PMID:33301706
Turning Nature's own processes into design strategies for living bone implant biomanufacturing: a decade of Developmental Engineering. PMID:33290762
Single-Cell Sequencing of Developing Human Gut Reveals Transcriptional Links to Childhood Crohn's Disease. PMID:33290721
Single-cell transcriptome profiling of an adult human cell atlas of 15 major organs. PMID:33287869
Single-Cell Transcriptomic Analysis Reveals BCMA CAR-T Cell Dynamics in a Patient with Refractory Primary Plasma Cell Leukemia. PMID:33278564
Applying high-dimensional single-cell technologies to the analysis of cancer immunotherapy. PMID:33277626
Microglia Diversity in Health and Multiple Sclerosis. PMID:33240276
CSEA-DB: an omnibus for human complex trait and cell type associations. PMID:33211888
Bone marrow adipogenic lineage precursors promote osteoclastogenesis in bone remodeling and pathologic bone loss. PMID:33206630
High-resolution transcriptional and morphogenetic profiling of cells from micropatterned human ESC gastruloid cultures. PMID:33206048
Decoding myofibroblast origins in human kidney fibrosis. PMID:33176333
Deciphering cell-cell interactions and communication from gene expression. PMID:33168968
Single nuclei RNA-seq of mouse placental labyrinth development. PMID:33141023
PlacentaCellEnrich: A tool to characterize gene sets using placenta cell-specific gene enrichment analysis. PMID:33137644
Single-Cell Transcriptomics Reveals Early Emergence of Liver Parenchymal and Non-parenchymal Cell Lineages. PMID:33125890
Phenotypic and functional characterization of first-trimester human placental macrophages, Hofbauer cells. PMID:33075123
Predicting cell-to-cell communication networks using NATMI. PMID:33024107
Microanatomy of the Human Atherosclerotic Plaque by Single-Cell Transcriptomics. PMID:32981416
Kidney Single-Cell Atlas Reveals Myeloid Heterogeneity in Progression and Regression of Kidney Disease. PMID:32978267
Single-cell genomics to understand disease pathogenesis. PMID:32951011
Multi-layered Spatial Transcriptomics Identify Secretory Factors Promoting Human Hematopoietic Stem Cell Development. PMID:32946788
Exploratory neuroimmune profiling identifies CNS-specific alterations in COVID-19 patients with neurological involvement. PMID:32935102
Single-cell transcriptomic atlas of primate cardiopulmonary aging. PMID:32913304
Identifying signaling genes in spatial single-cell expression data. PMID:32886099
Contribution of plasma cells and B cells to hidradenitis suppurativa pathogenesis. PMID:32853177
Differentiation of Human Intestinal Organoids with Endogenous Vascular Endothelial Cells. PMID:32841595
Single-Cell RNA Sequencing for Precision Oncology: Current State-of-Art. PMID:32837038
The T cell differentiation landscape is shaped by tumour mutations in lung cancer. PMID:32803172
The Application of Single-Cell RNA Sequencing in Vaccinology. PMID:32802896
Unraveling the Complexity of the Cancer Microenvironment With Multidimensional Genomic and Cytometric Technologies. PMID:32793500
Clinical value of DNA methylation markers in autoimmune rheumatic diseases. PMID:32759997
Vascular Homeostasis and Inflammation in Health and Disease-Lessons from Single Cell Technologies. PMID:32630148
Breathing fresh air into respiratory research with single-cell RNA sequencing. PMID:32620586
The history and advances in cancer immunotherapy: understanding the characteristics of tumor-infiltrating immune cells and their therapeutic implications. PMID:32612154
COVID-19 severity correlates with airway epithelium-immune cell interactions identified by single-cell analysis. PMID:32591762
Single-cell transcriptome and antigen-immunoglobin analysis reveals the diversity of B cells in non-small cell lung cancer. PMID:32580738
Functional crosstalk between T cells and monocytes in cancer and atherosclerosis. PMID:32531833
Co-expression of SARS-CoV-2 entry genes in the superficial adult human conjunctival, limbal and corneal epithelium suggests an additional route of entry via the ocular surface. PMID:32502616
Lineage-dependent gene expression programs influence the immune landscape of colorectal cancer. PMID:32451460
New avenues for systematically inferring cell-cell communication: through single-cell transcriptomics data. PMID:32435978
COMUNET: a tool to explore and visualize intercellular communication. PMID:32399572
Single-cell RNA sequencing demonstrates the molecular and cellular reprogramming of metastatic lung adenocarcinoma. PMID:32385277
A human lung tumor microenvironment interactome identifies clinically relevant cell-type cross-talk. PMID:32381040
Single-cell expression and Mendelian randomization analyses identify blood genes associated with lifespan and chronic diseases. PMID:32358504
Single Cell RNA Sequencing in Atherosclerosis Research. PMID:32324494
Single-Cell Analysis of Neuroinflammatory Responses Following Intracranial Injection of G-Deleted Rabies Viruses. PMID:32265666
Single cell RNA sequencing of 13 human tissues identify cell types and receptors of human coronaviruses. PMID:32199615
SingleCellSignalR: inference of intercellular networks from single-cell transcriptomics. PMID:32196115
Single cell approaches to address adipose tissue stromal cell heterogeneity. PMID:32026949
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transcriptomics
metasource: bio.tools
version: extracted_at: 2022-11-04T11:28:34.753500
immunoproteins and antigens
metasource: bio.tools
version: extracted_at: 2022-11-04T11:28:34.753500
rna-seq
metasource: bio.tools
version: extracted_at: 2022-11-04T11:28:34.753500
molecular interactions, pathways and networks
metasource: bio.tools
version: extracted_at: 2022-11-04T11:28:34.753500
literature and language
metasource: bio.tools
version: extracted_at: 2022-11-04T11:28:34.753500
Tags
More detailed information about this field from each metasource.
transcriptomics
metasource: bio.toolsversion: extracted_at: 2022-11-04T11:28:34.753500
immunoproteins and antigens
metasource: bio.toolsversion: extracted_at: 2022-11-04T11:28:34.753500
rna-seq
metasource: bio.toolsversion: extracted_at: 2022-11-04T11:28:34.753500
molecular interactions, pathways and networks
metasource: bio.toolsversion: extracted_at: 2022-11-04T11:28:34.753500
literature and language
metasource: bio.toolsversion: extracted_at: 2022-11-04T11:28:34.753500
transcriptomics immunoproteins and antigens rna sequence molecular interactions, pathways and networks literature and language
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