Tag: personalised medicine

Genomics England PanelApp is a publicly-available knowledgebase that allows virtual gene panels related to human disorders to be created, stored and queried. It includes a crowdsourcing tool that allows genes and genomic entities (short tandem repeat ...

The AlloMAPS database provides data on the energetics of communication in proteins with well-documented allosteric regulation, allosteric signalling in PDBselect chains, and allosteric effects of mutations. In addition to energetics of allosteric sig ...

An open-source platform to distribute and interpret data from multiplexed assays of variant effect. Table of Multiplexed Assay of Variant Effect (MAVE) studies. MaveDB - A repository for MAVE assay datasets. To cite this document, please use the c ...

lncRNA-associated ceRNA networks

PhenoDis is a manually annotated database providing symptomatic, genetic and imprinting information about rare cardiac diseases. PhenoDis is primarily concerned with the assignment of clinical symptoms to rare diseases using the biomedical literature ...

The GA4GH Toolkit outlines a suite of secure standards and frameworks that will enable more meaningful research and patient data harmonization and sharing. This suite addresses a variety of challenges across the data sharing life cycle and is applica ...

A computational genomic medicine platform for searching network perturbing alleles linking genotype to phenotype. My Personal Mutanome: A Personalized Cancer Medicine Platform for Searching Network Perturbing Alleles Linking Somatic Genotype to Phen ...

An international, open and dynamic library for up-to-date clinical information. Collect information about clinic management and research projects.

An updated database of experimentally supported ceRNA interactions and personalized networks contributing to precision medicine.

An authentic learning approach to teaching cancer genomics. On this site you can both (a) make and upload, and (b) download and analyse simulated patient case studies.

Heart Failure Integrated Platform (HFIP) is an integrated multi-omics data and knowledge platform for the precision medicine of heart failure.

A biomarker knowledge database for heart failure heterogeneity and personalized applications.

A database for tracking the contribution of genomics and precision health to the COVID-19 pandemic response.

DBPOM is a comprehensive database of pharmaco-omics for cancer precision medicine.

A manually curated and comprehensive knowledge base for myocardial infarction.

A platform for evidence-based drug annotation for genetic variants in cancer

A standardized database to study deep sequenced metagenomic data from human fecal specimen.

A Database for Exploring the Mutation Markers of Anti-Cancer Drug Sensitivity

GPCards is an integrated database of genotype-phenotype correlations in human genetic diseases.

SAMS is a database and phenotyping tool for precision medicine. Physicians can enter clinical signs from the Human Phenotype Ontology as well complete diagnoses, and patients can be involved by sharing the symptoms they encounter.

Chinese Millionome Database (CMDB), a database that contains 9.04 million single nucleotide variants (SNV) with allele frequency information derived from low-coverage (0.06×–0.1×) whole-genome sequencing (WGS) data of 141 431 unrelated healthy Chines ...

An integrative resource for investigating genetic model of drug response in cancer. An integrative database for investigating genetic model of drug response in cancer. iGMDR database collects predictive models of response for anti-cancer drugs. Th ...

a web server for allele-specific sgRNA design in precision medicine | Abstract Allele-specific targeting by CRISPR provides a point of entry for personalized gene therapy of dominantly inherited diseases, by selectively disrupting the mutant alleles ...

ClinGen Variant Curation Interface is a variant classification platform for the application of evidence criteria from ACMG/AMP guidelines.

LBD (Lymphoma Biomarker Database) is a manually curated database of literature-supported biomarkers for lymphoma. It contains 793 biomarkers (715 single biomarkers and 78 combined biomarkers) for different subtypes of lymphoma which have been verifie ...