Protein ANalysis THrough Evolutionary Relationships: Classification of Genes and Proteins
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Protein ANalysis THrough Evolutionary Relationships: Classification of Genes and Proteins
metasource: Fairsharing.org
version: FAIRsharing.org: PANTHER; Protein ANalysis THrough Evolutionary Relationships: Classification of Genes and Proteins; DOI: https://doi.org/10.25504/FAIRsharing.ty3dqs; Last edited: Jan. 8, 2019, 1:19 p.m.; Last accessed: Jan 03 2022 7:09 p.m.
PANTHER
metasource: Fairsharing.org
version: FAIRsharing.org: PANTHER; Protein ANalysis THrough Evolutionary Relationships: Classification of Genes and Proteins; DOI: https://doi.org/10.25504/FAIRsharing.ty3dqs; Last edited: Jan. 8, 2019, 1:19 p.m.; Last accessed: Jan 03 2022 7:09 p.m.
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657
Names
More detailed information about this field from each metasource.
Protein ANalysis THrough Evolutionary Relationships: Classification of Genes and Proteins
metasource: Fairsharing.orgversion: FAIRsharing.org: PANTHER; Protein ANalysis THrough Evolutionary Relationships: Classification of Genes and Proteins; DOI: https://doi.org/10.25504/FAIRsharing.ty3dqs; Last edited: Jan. 8, 2019, 1:19 p.m.; Last accessed: Jan 03 2022 7:09 p.m.
PANTHER
metasource: Fairsharing.orgversion: FAIRsharing.org: PANTHER; Protein ANalysis THrough Evolutionary Relationships: Classification of Genes and Proteins; DOI: https://doi.org/10.25504/FAIRsharing.ty3dqs; Last edited: Jan. 8, 2019, 1:19 p.m.; Last accessed: Jan 03 2022 7:09 p.m.
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657
Names
More detailed information about this field from each metasource.
Protein ANalysis THrough Evolutionary Relationships: Classification of Genes and Proteins
metasource: Fairsharing.orgversion: FAIRsharing.org: PANTHER; Protein ANalysis THrough Evolutionary Relationships: Classification of Genes and Proteins; DOI: https://doi.org/10.25504/FAIRsharing.ty3dqs; Last edited: Jan. 8, 2019, 1:19 p.m.; Last accessed: Jan 03 2022 7:09 p.m.
PANTHER
metasource: Fairsharing.orgversion: FAIRsharing.org: PANTHER; Protein ANalysis THrough Evolutionary Relationships: Classification of Genes and Proteins; DOI: https://doi.org/10.25504/FAIRsharing.ty3dqs; Last edited: Jan. 8, 2019, 1:19 p.m.; Last accessed: Jan 03 2022 7:09 p.m.
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657
The PANTHER (Protein ANalysis THrough Evolutionary Relationships) Classification System is a unique resource that classifies genes by their functions, using published scientific experimental evidence and evolutionary relationships to predict function even in the absence of direct experimental evidence.
Description
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The PANTHER (Protein ANalysis THrough Evolutionary Relationships) Classification System is a unique resource that classifies genes by their functions, using published scientific experimental evidence and evolutionary relationships to predict function even in the absence of direct experimental evidence.
metasource: Fairsharing.orgversion: FAIRsharing.org: PANTHER; Protein ANalysis THrough Evolutionary Relationships: Classification of Genes and Proteins; DOI: https://doi.org/10.25504/FAIRsharing.ty3dqs; Last edited: Jan. 8, 2019, 1:19 p.m.; Last accessed: Jan 03 2022 7:09 p.m.
PANTHER (Protein Analysis Through Evolutionary Relationships, http://www.pantherdb.org) is a resource for the evolutionary and functional classification of protein-coding genes from all domains of life. The evolutionary classification is based on a library of over 15,000 phylogenetic trees, and the functional classifications include Gene Ontology terms and pathways. Here, we analyze the current coverage of genes from genomes in different taxonomic groups, so that users can better understand what to expect when analyzing a gene list using PANTHER tools. We also describe extensive improvements to PANTHER made in the past two years. The PANTHER Protein Class ontology has been completely refactored, and 6101 PANTHER families have been manually assigned to a Protein Class, providing a high level classification of protein families and their genes. Users can access the TreeGrafter tool to add their own protein sequences to the reference phylogenetic trees in PANTHER, to infer evolutionary context as well as fine-grained annotations. We have added human enhancer-gene links that associate non-coding regions with the annotated human genes in PANTHER. We have also expanded the available services for programmatic access to PANTHER tools and data via application programming interfaces (APIs). Other improvements include additional plant genomes and an updated PANTHER GO-slim.
metasource: Nucleic Acid Research database catalogueversion: extracted_at: 2022-11-04T11:16:25.468657
Webpage:
http://www.pantherdb.orgWebpage
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http://www.pantherdb.org
metasource: Fairsharing.orgversion: FAIRsharing.org: PANTHER; Protein ANalysis THrough Evolutionary Relationships: Classification of Genes and Proteins; DOI: https://doi.org/10.25504/FAIRsharing.ty3dqs; Last edited: Jan. 8, 2019, 1:19 p.m.; Last accessed: Jan 03 2022 7:09 p.m.
http://www.pantherdb.org/
metasource: Nucleic Acid Research database catalogueversion: extracted_at: 2022-11-04T11:16:25.468657
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Name: Panther DB Data Policies and DisclaimerLicence name
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Panther DB Data Policies and Disclaimer
metasource: Fairsharing.orgversion: FAIRsharing.org: PANTHER; Protein ANalysis THrough Evolutionary Relationships: Classification of Genes and Proteins; DOI: https://doi.org/10.25504/FAIRsharing.ty3dqs; Last edited: Jan. 8, 2019, 1:19 p.m.; Last accessed: Jan 03 2022 7:09 p.m.
Licence URL
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http://www.pantherdb.org/terms/disclaimer.jsp
metasource: Fairsharing.orgversion: FAIRsharing.org: PANTHER; Protein ANalysis THrough Evolutionary Relationships: Classification of Genes and Proteins; DOI: https://doi.org/10.25504/FAIRsharing.ty3dqs; Last edited: Jan. 8, 2019, 1:19 p.m.; Last accessed: Jan 03 2022 7:09 p.m.
Publications:
(6)
Publications
More detailed information about this field from each metasource.
PANTHER: a library of protein families and subfamilies indexed by function
PMID: 12952881
metasource: Fairsharing.org
version: FAIRsharing.org: PANTHER; Protein ANalysis THrough Evolutionary Relationships: Classification of Genes and Proteins; DOI: https://doi.org/10.25504/FAIRsharing.ty3dqs; Last edited: Jan. 8, 2019, 1:19 p.m.; Last accessed: Jan 03 2022 7:09 p.m.
Large-scale gene function analysis with the PANTHER classification system
PMID: 23868073
metasource: Fairsharing.org
version: FAIRsharing.org: PANTHER; Protein ANalysis THrough Evolutionary Relationships: Classification of Genes and Proteins; DOI: https://doi.org/10.25504/FAIRsharing.ty3dqs; Last edited: Jan. 8, 2019, 1:19 p.m.; Last accessed: Jan 03 2022 7:09 p.m.
PANTHER version 11: expanded annotation data from Gene Ontology and Reactome pathways, and data analysis tool enhancements
PMID: 27899595
metasource: Fairsharing.org
version: FAIRsharing.org: PANTHER; Protein ANalysis THrough Evolutionary Relationships: Classification of Genes and Proteins; DOI: https://doi.org/10.25504/FAIRsharing.ty3dqs; Last edited: Jan. 8, 2019, 1:19 p.m.; Last accessed: Jan 03 2022 7:09 p.m.
PANTHER pathway: an ontology-based pathway database coupled with data analysis tools
PMID: 19597783
metasource: Fairsharing.org
version: FAIRsharing.org: PANTHER; Protein ANalysis THrough Evolutionary Relationships: Classification of Genes and Proteins; DOI: https://doi.org/10.25504/FAIRsharing.ty3dqs; Last edited: Jan. 8, 2019, 1:19 p.m.; Last accessed: Jan 03 2022 7:09 p.m.
PANTHER-PSEP: predicting disease-causing genetic variants using position-specific evolutionary preservation
PMID: 27193693
metasource: Fairsharing.org
version: FAIRsharing.org: PANTHER; Protein ANalysis THrough Evolutionary Relationships: Classification of Genes and Proteins; DOI: https://doi.org/10.25504/FAIRsharing.ty3dqs; Last edited: Jan. 8, 2019, 1:19 p.m.; Last accessed: Jan 03 2022 7:09 p.m.
https://doi.org/10.1093/nar/gkaa1106
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657
Publications
More detailed information about this field from each metasource.
PANTHER: a library of protein families and subfamilies indexed by function
PMID: 12952881
metasource: Fairsharing.org
version: FAIRsharing.org: PANTHER; Protein ANalysis THrough Evolutionary Relationships: Classification of Genes and Proteins; DOI: https://doi.org/10.25504/FAIRsharing.ty3dqs; Last edited: Jan. 8, 2019, 1:19 p.m.; Last accessed: Jan 03 2022 7:09 p.m.
Large-scale gene function analysis with the PANTHER classification system
PMID: 23868073
metasource: Fairsharing.org
version: FAIRsharing.org: PANTHER; Protein ANalysis THrough Evolutionary Relationships: Classification of Genes and Proteins; DOI: https://doi.org/10.25504/FAIRsharing.ty3dqs; Last edited: Jan. 8, 2019, 1:19 p.m.; Last accessed: Jan 03 2022 7:09 p.m.
PANTHER version 11: expanded annotation data from Gene Ontology and Reactome pathways, and data analysis tool enhancements
PMID: 27899595
metasource: Fairsharing.org
version: FAIRsharing.org: PANTHER; Protein ANalysis THrough Evolutionary Relationships: Classification of Genes and Proteins; DOI: https://doi.org/10.25504/FAIRsharing.ty3dqs; Last edited: Jan. 8, 2019, 1:19 p.m.; Last accessed: Jan 03 2022 7:09 p.m.
PANTHER pathway: an ontology-based pathway database coupled with data analysis tools
PMID: 19597783
metasource: Fairsharing.org
version: FAIRsharing.org: PANTHER; Protein ANalysis THrough Evolutionary Relationships: Classification of Genes and Proteins; DOI: https://doi.org/10.25504/FAIRsharing.ty3dqs; Last edited: Jan. 8, 2019, 1:19 p.m.; Last accessed: Jan 03 2022 7:09 p.m.
PANTHER-PSEP: predicting disease-causing genetic variants using position-specific evolutionary preservation
PMID: 27193693
metasource: Fairsharing.org
version: FAIRsharing.org: PANTHER; Protein ANalysis THrough Evolutionary Relationships: Classification of Genes and Proteins; DOI: https://doi.org/10.25504/FAIRsharing.ty3dqs; Last edited: Jan. 8, 2019, 1:19 p.m.; Last accessed: Jan 03 2022 7:09 p.m.
https://doi.org/10.1093/nar/gkaa1106
metasource: Nucleic Acid Research database catalogueversion: extracted_at: 2022-11-04T11:16:25.468657
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PANTHER: a library of protein families and subfamilies indexed by function
PubMed citations: 1383.
1383 articles citing: PANTHER: a library of protein families and subfamilies indexed by function
A brain precursor atlas reveals the acquisition of developmental-like states in adult cerebral tumours. PMID:35853870
Influence of Padina gymnospora on Apoptotic Proteins of Oral Cancer Cells-a Proteome-Wide Analysis. PMID:35849254
The cGAS-STING Pathway Affects Vertebral Bone but Does Not Promote Intervertebral Disc Cell Senescence or Degeneration. PMID:35769461
From drug repositioning to target repositioning: prediction of therapeutic targets using genetically perturbed transcriptomic signatures. PMID:35758779
Proteomic characterization of phagocytic primary human monocyte-derived macrophages. PMID:35755185
miRNAs Copy Number Variations Repertoire as Hallmark Indicator of Cancer Species Predisposition. PMID:35741808
Effect of the Symbiosis with Mycoplasma hominis and Candidatus Mycoplasma Girerdii on Trichomonas vaginalis Metronidazole Susceptibility. PMID:35740218
Dysregulated Gene Expression in Lymphoblasts from Parkinson's Disease. PMID:35736800
The chromosome-level genome for Toxicodendron vernicifluum provides crucial insights into Anacardiaceae evolution and urushiol biosynthesis. PMID:35733792
Mechanistic insight of the potential of geraniol against Alzheimer's disease. PMID:35701806
Single-cell analysis of human basal cell carcinoma reveals novel regulators of tumor growth and the tumor microenvironment. PMID:35687691
Neuropilin-1 is present on Foxp3+ T regulatory cell-derived small extracellular vesicles and mediates immunity against skin transplantation. PMID:35676234
Developing a bioinformatics pipeline for comparative protein classification analysis. PMID:35668373
Radiotherapy-activated NBTXR3 nanoparticles modulate cancer cell immunogenicity and TCR repertoire. PMID:35659676
Brain proteome profiling implicates the complement and coagulation cascade in multiple system atrophy brain pathology. PMID:35657417
BETA: a comprehensive benchmark for computational drug-target prediction. PMID:35649342
Annotation Query (AnnoQ): an integrated and interactive platform for large-scale genetic variant annotation. PMID:35640593
Endothelial Cell Protein Targeting by Myeloperoxidase-Derived 2-Chlorofatty Aldehyde. PMID:35624804
Strawberry notch homolog 2 regulates the response to interleukin-6 in the central nervous system. PMID:35624480
Two Different Species of Mycoplasma Endosymbionts Can Influence Trichomonas vaginalis Pathophysiology. PMID:35608298
An Arabidopsis pre-RNA processing8a (prp8a) missense allele restores splicing of a subset of mis-spliced mRNAs. PMID:35608297
Arabidopsis transcription factor TCP4 represses chlorophyll biosynthesis to prevent petal greening. PMID:35605201
Multi-Omics Analysis of Glioblastoma and Glioblastoma Cell Line: Molecular Insights Into the Functional Role of GPR56 and TG2 in Mesenchymal Transition. PMID:35600402
Epigenetic mechanisms of lung carcinogenesis involve differentially methylated CpG sites beyond those associated with smoking. PMID:35595947
Transcriptomic Profiling Revealed Lnc-GOLGA6A-1 as a Novel Prognostic Biomarker of Meningioma Recurrence. PMID:35551164
Novel Genomic Regions Linked to Ascochyta Blight Resistance in Two Differentially Resistant Cultivars of Chickpea. PMID:35548283
Mutational pattern of PIK3CA exon 20 in circulating DNA in breast cancer. PMID:35531214
Proteomic analysis of autoimmune retinopathy implicates NrCAM as a potential biomarker. PMID:35529077
A rice protein interaction network reveals high centrality nodes and candidate pathogen effector targets. PMID:35521542
Potential Biomarkers of Acute Ischemic Stroke Etiology Revealed by Mass Spectrometry-Based Proteomic Characterization of Formalin-Fixed Paraffin-Embedded Blood Clots. PMID:35518205
PRD-Class Homeobox Genes in Bovine Early Embryos: Function, Evolution, and Overlapping Roles. PMID:35512670
Gaur genome reveals expansion of sperm odorant receptors in domesticated cattle. PMID:35508966
Genome interpretation using in silico predictors of variant impact. PMID:35488922
Genome-wide DNA Methylation Differences in Nonfunctioning Pituitary Adenomas With and Without Postsurgical Progression. PMID:35485764
Copper Metabolism in Naegleria gruberi and Its Deadly Relative Naegleria fowleri. PMID:35478954
ZNF117 regulates glioblastoma stem cell differentiation towards oligodendroglial lineage. PMID:35459228
Circular RNA Profiles in Viremia and ART Suppression Predict Competing circRNA-miRNA-mRNA Networks Exclusive to HIV-1 Viremic Patients. PMID:35458413
The Tudor Domain-Containing Protein, Kotsubu (CG9925), Localizes to the Nuage and Functions in piRNA Biogenesis in D. melanogaster. PMID:35425810
A translation control module coordinates germline stem cell differentiation with ribosome biogenesis during Drosophila oogenesis. PMID:35413237
Preclinical Studies on Convalescent Human Immune Plasma-Derived Exosome: Omics and Antiviral Properties to SARS-CoV-2. PMID:35401544
Proteomic and Phosphoproteomic Changes of MAPK-Related Inflammatory Response in an Animal Model of Neuropathic Pain by Differential Target Multiplexed SCS and Low-Rate SCS. PMID:35392631
Neutrophil and natural killer cell imbalances prevent muscle stem cell-mediated regeneration following murine volumetric muscle loss. PMID:35377804
Circulating Tumor Cell-Free DNA Genes as Prognostic Gene Signature for Platinum Resistant Ovarian Cancer Diagnosis. PMID:35370397
Total-Body Irradiation Is Associated With Increased Incidence of Mesenchymal Neoplasia in a Radiation Late Effects Cohort of Rhesus Macaques (Macaca mulatta). PMID:35361520
ALGAEFUN with MARACAS, microALGAE FUNctional enrichment tool for MicroAlgae RnA-seq and Chip-seq AnalysiS. PMID:35361110
Computational analyses of mechanism of action (MoA): data, methods and integration. PMID:35360890
A Phase 1/2 Trial Combining Avelumab and Trabectedin for Advanced Liposarcoma and Leiomyosarcoma. PMID:35349638
Clr-f expression regulates kidney immune and metabolic homeostasis. PMID:35318366
Control of spinal motor neuron terminal differentiation through sustained Hoxc8 gene activity. PMID:35315772
Identification of novel alternative splicing associated with mastitis disease in Holstein dairy cows using large gap read mapping. PMID:35305573
Mining for New Sources of Resistance to Powdery Mildew in Genetic Resources of Winter Wheat. PMID:35300015
Peripheral blood mononuclear cell gene expression and cytokine profiling in patients with intermittent claudication who exhibit exercise induced acute renal injury. PMID:35298547
Novel alleles gained during the Beringian isolation period. PMID:35277570
Reconstruction and analysis of a large-scale binary Ras-effector signaling network. PMID:35246154
PUCHI represses early meristem formation in developing lateral roots of Arabidopsis thaliana. PMID:35224628
Organoids from human tooth showing epithelial stemness phenotype and differentiation potential. PMID:35217915
Unraveling the Genome Sequence of Plant Growth Promoting Aspergillus niger (CSR3) Provides Insight into the Synthesis of Secondary Metabolites and Its Comparative Genomics. PMID:35205861
Deep analysis of neuroblastoma core regulatory circuitries using online databases and integrated bioinformatics shows their pan-cancer roles as prognostic predictors. PMID:35201514
E-Protein Inhibition in ILC2 Development Shapes the Function of Mature ILC2s during Allergic Airway Inflammation. PMID:35181641
HIV-1 Tat and cocaine coexposure impacts piRNAs to affect astrocyte energy metabolism. PMID:35170353
Characterization of the 3'UTR of the BTD gene and identification of regulatory elements and microRNAs. PMID:35167647
Zebrafish information network, the knowledgebase for Danio rerio research. PMID:35166825
Transcriptomic Profile of Canine DH82 Macrophages Infected by Leishmania infantum Promastigotes with Different Virulence Behavior. PMID:35163386
Transcriptome-wide changes in gene expression, splicing, and lncRNAs in response to a live attenuated dengue virus vaccine. PMID:35139383
De novo and comparative transcriptomic analysis explain morphological differences in Panax notoginseng taproots. PMID:35100996
Hif1α and Wnt are required for posterior gene expression during Xenopus tropicalis tail regeneration. PMID:35065905
Capturing SNP Association across the NK Receptor and HLA Gene Regions in Multiple Sclerosis by Targeted Penalised Regression Models. PMID:35052430
Differential target multiplexed spinal cord stimulation programming modulates proteins involved in ion regulation in an animal model of neuropathic pain. PMID:35048719
Mitonuclear incompatibility as a hidden driver behind the genome ancestry of African admixed cattle. PMID:35039029
Effect of aneuploidy of a non-essential chromosome on gene expression in maize. PMID:34997647
Analysis of coding variants in the human FTO gene from the gnomAD database. PMID:34990463
Ataxin-2 is essential for cytoskeletal dynamics and neurodevelopment in Drosophila. PMID:34977501
The splicing factor DHX38/PRP16 is required for ovarian clear cell carcinoma tumorigenesis, as revealed by a CRISPR-Cas9 screen. PMID:34965029
Effects of Simultaneous Exposure to a Western Diet and Wheel-Running Training on Brain Energy Metabolism in Female Rats. PMID:34959794
Proteomic profiling reveals engineered chitosan nanoparticles mediated cellular crosstalk and immunomodulation for therapeutic application in apical periodontitis. PMID:34938914
Chromatin Landscape Dynamics in the Early Development of the Plant Parasitic Nematode Meloidogyne incognita. PMID:34938734
In-silico analysis reveals druggable single nucleotide polymorphisms in angiotensin 1 converting enzyme involved in the onset of blood pressure. PMID:34930451
Transcriptome-Wide Analyses Identify Dominant as the Predominantly Non-Conservative Alternative Splicing Inheritance Patterns in F1 Chickens. PMID:34925458
Network Analysis of Microarray Data. PMID:34902128
Navigating Multi-Scale Cancer Systems Biology Towards Model-Driven Clinical Oncology and Its Applications in Personalized Therapeutics. PMID:34900668
Overexpression screen of interferon-stimulated genes identifies RARRES3 as a restrictor of Toxoplasma gondii infection. PMID:34871166
Shoot and root single cell sequencing reveals tissue- and daytime-specific transcriptome profiles. PMID:34850215
Accurate expression quantification from nanopore direct RNA sequencing with NanoCount. PMID:34850115
Transcription Factor Action Orchestrates the Complex Expression Pattern of CRABS CLAW in Arabidopsis. PMID:34828269
Genome-wide transcriptome signatures of ant-farmed Squamellaria epiphytes reveal key functions in a unique symbiosis. PMID:34824797
Comparative genomics suggests local adaptations in the invasive small hive beetle. PMID:34824789
Development of a bioinformatics platform for analysis of quantitative transcriptomics and proteomics data: the OMnalysis. PMID:34820180
Ensembl Genomes 2022: an expanding genome resource for non-vertebrates. PMID:34791415
A joint analysis using exome and transcriptome data identifiescandidate polymorphisms and genes involved with umbilical hernia in pigs. PMID:34773987
Which Is the Best In Silico Program for the Missense Variations in IDUA Gene? A Comparison of 33 Programs Plus a Conservation Score and Evaluation of 586 Missense Variants. PMID:34746235
Rapid adaptation through genomic and epigenomic responses following translocations in an endangered salmonid. PMID:34745338
LncRNA Hmrhl regulates expression of cancer related genes in chronic myelogenous leukemia through chromatin association. PMID:34734184
miR-146a modulates TLR1/2 and 4 induced inflammation and links it with proliferation and lipid production via the indirect regulation of GNG7 in human SZ95 sebocytes. PMID:34728702
Toward Integrated Multi-Omics Intervention: Rice Trait Improvement and Stress Management. PMID:34721467
PhylomeDB V5: an expanding repository for genome-wide catalogues of annotated gene phylogenies. PMID:34718760
PANTHER: Making genome-scale phylogenetics accessible to all. PMID:34717010
Statin-mediated disruption of Rho GTPase prenylation and activity inhibits respiratory syncytial virus infection. PMID:34716403
Chromatin Remodelers Interact with Eya1 and Six2 to Target Enhancers to Control Nephron Progenitor Cell Maintenance. PMID:34716243
Genome-wide screening of novel RT-qPCR reference genes for study of GLRaV-3 infection in wine grapes and refinement of an RNA isolation protocol for grape berries. PMID:34711253
SLC25A39 is necessary for mitochondrial glutathione import in mammalian cells. PMID:34707288
K2P18.1 translates T cell receptor signals into thymic regulatory T cell development. PMID:34702947
Methylation of the tyrosine hydroxylase gene is dysregulated by cocaine dependence in the human striatum. PMID:34693223
The fungal root endophyte Serendipita vermifera displays inter-kingdom synergistic beneficial effects with the microbiota in Arabidopsis thaliana and barley. PMID:34686763
De Novo Genome Assembly of Chinese Plateau Honeybee Unravels Intraspecies Genetic Diversity in the Eastern Honeybee, Apis cerana. PMID:34680661
In silico Approach for Validating and Unveiling New Applications for Prognostic Biomarkers of Endometrial Cancer. PMID:34680205
Whole-Genome Sequencing and Genome-Wide Studies of Spiny Head Croaker (Collichthys lucidus) Reveals Potential Insights for Well-Developed Otoliths in the Family Sciaenidae. PMID:34659355
Short single-stranded DNAs with putative non-canonical structures comprise a new class of plasma cell-free DNA. PMID:34649537
TIGER: The gene expression regulatory variation landscape of human pancreatic islets. PMID:34644572
RNA-Seq reveals different responses to drought in Neotropical trees from savannas and seasonally dry forests. PMID:34641780
The genetic impact of an Ebola outbreak on a wild gorilla population. PMID:34635054
Transcriptomic analysis revealed increased expression of genes involved in keratinization in the tears of COVID-19 patients. PMID:34615949
Differential regulation of mRNA fate by the human Ccr4-Not complex is driven by coding sequence composition and mRNA localization. PMID:34615539
Genetic Analysis of Heterosis for Yield Influencing Traits in Brassica juncea Using a Doubled Haploid Population and Its Backcross Progenies. PMID:34603351
Recurrence-associated gene signature in patients with stage I non-small-cell lung cancer. PMID:34599262
A differential DNA methylome signature of pulmonary immune cells from individuals converting to latent tuberculosis infection. PMID:34593857
Identification of potential pathogenic mutations in Chinese children with first branchial cleft anomalies detected by whole-exome sequencing. PMID:34589676
RNA-RNA interactions between SARS-CoV-2 and host benefit viral development and evolution during COVID-19 infection. PMID:34585235
Genome-Wide Identification and Analyses of Drought/Salt-Responsive Cytochrome P450 Genes in Medicago truncatula. PMID:34576120
Protective Effect of Crocin on Malathion-induced Cardiotoxicity in Rats: A Biochemical, Histopathological and Proteomics Study. PMID:34567153
Quantitative proteomic analysis after neuroprotective MyD88 inhibition in the retinal degeneration 10 mouse. PMID:34562309
Identification of essential genes in Caenorhabditis elegans through whole-genome sequencing of legacy mutant collections. PMID:34550348
Prevalence and species distribution of the low-complexity, amyloid-like, reversible, kinked segment structural motif in amyloid-like fibrils. PMID:34537246
KinOrtho: a method for mapping human kinase orthologs across the tree of life and illuminating understudied kinases. PMID:34537014
Unraveling the Relevance of ARL GTPases in Cutaneous Melanoma Prognosis through Integrated Bioinformatics Analysis. PMID:34502169
Recipient APOL1 risk alleles associate with death-censored renal allograft survival and rejection episodes. PMID:34499625
Kinase-Catalyzed Biotinylation to Map Cell Signaling Pathways: Application to Epidermal Growth Factor Signaling. PMID:34491762
The investigation of nonsynonymous SNPs of human SLC6A4 gene associated with depression: An in silico approach. PMID:34466701
The α-Arrestin ARRDC3 Is an Emerging Multifunctional Adaptor Protein in Cancer. PMID:34465145
Regulatory T cells promote innate inflammation after skin barrier breach via TGF-β activation. PMID:34452925
A TALE/HOX code unlocks WNT signalling response towards paraxial mesoderm. PMID:34446717
Programmed Cell Death in Developing Brachypodium distachyon Grain. PMID:34445790
Proteomic Analysis of Niemann-Pick Type C Hepatocytes Reveals Potential Therapeutic Targets for Liver Damage. PMID:34440927
Overexpression and Activation of αvβ3 Integrin Differentially Affects TGFβ2 Signaling in Human Trabecular Meshwork Cells. PMID:34440692
Bothrops Jararaca Snake Venom Modulates Key Cancer-Related Proteins in Breast Tumor Cell Lines. PMID:34437390
TCF19 Impacts a Network of Inflammatory and DNA Damage Response Genes in the Pancreatic β-Cell. PMID:34436454
Reciprocal YAP1 loss and INSM1 expression in neuroendocrine prostate cancer. PMID:34431104
Excitotoxic stimulation activates distinct pathogenic and protective expression signatures in the hippocampus. PMID:34414662
Cadherin and Wnt signaling pathways as key regulators in diabetic nephropathy. PMID:34411124
Genomics pipelines to investigate susceptibility in whole genome and exome sequenced data for variant discovery, annotation, prediction and genotyping. PMID:34395068
Aspergillus sp. A31 and Curvularia geniculata P1 mitigate mercury toxicity to Oryza sativa L. PMID:34387704
Mapping gene and gene pathways associated with coronary artery disease: a CARDIoGRAM exome and multi-ancestry UK biobank analysis. PMID:34385509
Altered hippocampal transcriptome dynamics following sleep deprivation. PMID:34384474
The genome of a nonphotosynthetic diatom provides insights into the metabolic shift to heterotrophy and constraints on the loss of photosynthesis. PMID:34379807
Pathogenic nsSNPs that increase the risks of cancers among the Orang Asli and Malays. PMID:34373545
Developmental Alcohol Exposure in Drosophila: Effects on Adult Phenotypes and Gene Expression in the Brain. PMID:34366927
Computational and Mass Spectrometry-Based Approach Identify Deleterious Non-Synonymous Single Nucleotide Polymorphisms (nsSNPs) in JMJD6. PMID:34361805
Genome-wide association study of trypanosome prevalence and morphometric traits in purebred and crossbred Baoulé cattle of Burkina Faso. PMID:34351956
Identification of TBX15 as an adipose master trans regulator of abdominal obesity genes. PMID:34340684
Contribution of Congenital Heart Disorders Associated With Copy Number Variants in Mediating Risk for Brain Developmental Disorders: Evidence From 20-Year Retrospective Cohort Study. PMID:34336942
Draft Genome of the Mirrorwing Flyingfish (Hirundichthys speculiger). PMID:34306036
Changes to the identity of EndoC-βH1 beta cells may be mediated by stress-induced depletion of HNRNPD. PMID:34301309
The tweety Gene Family: From Embryo to Disease. PMID:34262434
Heat Stress-Dependent Association of Membrane Trafficking Proteins With mRNPs Is Selective. PMID:34249042
The commensal bacterium Lactiplantibacillus plantarum imprints innate memory-like responses in mononuclear phagocytes. PMID:34224309
The pattern of gene copy number alteration (CNAs) in hepatocellular carcinoma: an in silico analysis. PMID:34215297
IGFBP2 Is a Potential Master Regulator Driving the Dysregulated Gene Network Responsible for Short Survival in Glioblastoma Multiforme. PMID:34211498
Phytochemically rich dietary components and the risk of colorectal cancer: A systematic review and meta-analysis of observational studies. PMID:34189071
P23 Acts as Functional RBP in the Macrophage Inflammation Response. PMID:34179071
Genomic consequences of human-mediated translocations in margin populations of an endangered amphibian. PMID:34178108
Analysis of gene network bifurcation during optic cup morphogenesis in zebrafish. PMID:34162866
Schistosomiasis Drug Discovery in the Era of Automation and Artificial Intelligence. PMID:34135888
The cryptic gonadotropin-releasing hormone neuronal system of human basal ganglia. PMID:34128468
Revisiting the Characteristics of Testicular Germ Cell Lines GC-1(spg) and GC-2(spd)ts. PMID:34125394
Automated generation of context-specific gene regulatory networks with a weighted approach in Drosophila melanogaster. PMID:34123358
netgsa: Fast computation and interactive visualization for topology-based pathway enrichment analysis. PMID:34115744
Systematic quantification of the dynamics of newly synthesized proteins unveiling their degradation pathways in human cells. PMID:34109028
Lgr6 marks epidermal stem cells with a nerve-dependent role in wound re-epithelialization. PMID:34102139
Molecular omics resources should require sex annotation: a call for action. PMID:34099934
Mitochondrial disease patients with novel ND4 12058A > C and ND1 m.3911A > G variations: implications for a role in the phenotype following a bioinformatic investigation. PMID:34089464
A KMT2A-AFF1 gene regulatory network highlights the role of core transcription factors and reveals the regulatory logic of key downstream target genes. PMID:34088716
A forward genetics approach integrating genome-wide association study and expression quantitative trait locus mapping to dissect leaf development in maize (Zea mays). PMID:34087008
Co-expression Network Revealed Roles of RNA m6A Methylation in Human β-Cell of Type 2 Diabetes Mellitus. PMID:34084770
Nuclear Phosphatidylinositol 3,4,5-Trisphosphate Interactome Uncovers an Enrichment in Nucleolar Proteins. PMID:34048982
Chromosomal copy number heterogeneity predicts survival rates across cancers. PMID:34045449
Morpho-Physiological and Proteomic Response of Bt-Cotton and Non-Bt Cotton to Drought Stress. PMID:34040622
The Drosophila brain on cocaine at single-cell resolution. PMID:34035044
Health monitoring in birds using bio-loggers and whole blood transcriptomics. PMID:34031452
Transcriptomic and metabolomic characterization of post-hatch metabolic reprogramming during hepatic development in the chicken. PMID:34030631
Drainage-structuring of ancestral variation and a common functional pathway shape limited genomic convergence in natural high- and low-predation guppies. PMID:34029313
Core-binding factor leukemia hijacks the T-cell-prone PU.1 antisense promoter. PMID:34010414
Integration of 1:1 orthology maps and updated datasets into Echinobase. PMID:34010390
Generation of an isoform-level transcriptome atlas of macrophage activation. PMID:34000296
Profilin2 regulates actin rod assembly in neuronal cells. PMID:33986363
Extracellular vesicle-enriched miRNA profiles across pregnancy in the MADRES cohort. PMID:33979365
The RNA landscape of the human placenta in health and disease. PMID:33976128
Comparative transcriptomics between Drosophila mojavensis and D. arizonae reveals transgressive gene expression and underexpression of spermatogenesis-related genes in hybrid testes. PMID:33972659
Short chain fatty acids delay the development of hepatocellular carcinoma in HBx transgenic mice. PMID:33945993
Caveolin-1-driven membrane remodelling regulates hnRNPK-mediated exosomal microRNA sorting in cancer. PMID:33931969
Combined VEGFR and MAPK pathway inhibition in angiosarcoma. PMID:33931674
Dnmt2-null sperm block maternal transmission of a paramutant phenotype†. PMID:33929014
Machine Learning Neuroprotective Strategy Reveals a Unique Set of Parkinson Therapeutic Nicotine Analogs. PMID:33927788
TNF-α differentially modulates subunit levels of respiratory electron transport complexes of ER/PR +ve/-ve breast cancer cells to regulate mitochondrial complex activity and tumorigenic potential. PMID:33926547
mRNA Expressions of Candidate Genes in Gestational Day 16 Conceptus and Corresponding Endometrium in Repeat Breeder Dairy Cows with Suboptimal Uterine Environment Following Transfer of Different Quality Day 7 Embryos. PMID:33920430
Genome-Wide Mapping of Histone H3 Lysine 4 Trimethylation (H3K4me3) and Its Involvement in Fatty Acid Biosynthesis in Sunflower Developing Seeds. PMID:33917507
The long non-coding RNA MIR31HG regulates the senescence associated secretory phenotype. PMID:33911076
Translational control of gene expression by eIF2 modulates proteostasis and extends lifespan. PMID:33901016
Altered Transcription Factor Expression Responses to Exercise in Insulin Resistance. PMID:33897458
Temporal proteomic changes induced by nicotine in human cells: A quantitative proteomics approach. PMID:33895337
Toward Colorectal Cancer Biomarkers: The Role of Genetic Variation, Wnt Pathway, and Long Noncoding RNAs. PMID:33891491
An EPIC predictor of gestational age and its application to newborns conceived by assisted reproductive technologies. PMID:33875015
Systematic identification of A-to-I RNA editing in zebrafish development and adult organs. PMID:33872356
NASA GeneLab RNA-seq consensus pipeline: standardized processing of short-read RNA-seq data. PMID:33870146
The molecular signatures of compatible and incompatible pollination in Arabidopsis. PMID:33853522
The connectome of neural crest enhancers reveals regulatory features of signaling systems. PMID:33852891
Length variation in short tandem repeats affects gene expression in natural populations of Arabidopsis thaliana. PMID:33848350
Coding and non-coding roles of MOCCI (C15ORF48) coordinate to regulate host inflammation and immunity. PMID:33837217
iTRAQ-based proteome profiling revealed the role of Phytochrome A in regulating primary metabolism in tomato seedling. PMID:33824368
Functional assessment of the "two-hit" model for neurodevelopmental defects in Drosophila and X. laevis. PMID:33819264
Cell-type specific analysis of physiological action of estrogen in mouse oviducts. PMID:33818810
Covalent Cysteine Targeting of Bruton's Tyrosine Kinase (BTK) Family by Withaferin-A Reduces Survival of Glucocorticoid-Resistant Multiple Myeloma MM1 Cells. PMID:33807411
Probing into the Effects of Grapevine Leafroll-Associated Viruses on the Physiology, Fruit Quality and Gene Expression of Grapes. PMID:33807294
Protective Effects of Cannabidiol on the Membrane Proteome of UVB-Irradiated Keratinocytes. PMID:33800305
Discovery of RSV-Induced BRD4 Protein Interactions Using Native Immunoprecipitation and Parallel Accumulation-Serial Fragmentation (PASEF) Mass Spectrometry. PMID:33799525
C21orf91 Regulates Oligodendroglial Precursor Cell Fate-A Switch in the Glial Lineage? PMID:33796011
Regenerative cross talk between cardiac cells and macrophages. PMID:33769920
SBGN Bricks Ontology as a tool to describe recurring concepts in molecular networks. PMID:33758926
The AIM2 inflammasome exacerbates atherosclerosis in clonal haematopoiesis. PMID:33731931
Genotype-by-environment interaction in Holstein heifer fertility traits using single-step genomic reaction norm models. PMID:33731012
Extracellular signal-regulated kinase regulates microglial immune responses in Alzheimer's disease. PMID:33729626
Computational approach to decipher cellular interactors and drug targets during co-infection of SARS-CoV-2, Dengue, and Chikungunya virus. PMID:33723515
In vitro and in silico assessment of the effect of WWOX expression on invasiveness pathways associated with AP-2 transcription factors in bladder cancer. PMID:33691672
Genomic imbalance determines positive and negative modulation of gene expression in diploid maize. PMID:33677584
Comparison of plasma and cerebrospinal fluid proteomes identifies gene products guiding adult neurogenesis and neural differentiation in birds. PMID:33674647
Dysregulated Provision of Oxidisable Substrates to the Mitochondria in ME/CFS Lymphoblasts. PMID:33669532
Identification of Host Factors Associated with the Development of Equine Herpesvirus Myeloencephalopathy by Transcriptomic Analysis of Peripheral Blood Mononuclear Cells from Horses. PMID:33668216
Neuron-specific spinal cord translatomes reveal a neuropeptide code for mouse dorsal horn excitatory neurons. PMID:33664406
Integrated analysis of label-free quantitative proteomics and bioinformatics reveal insights into signaling pathways in male breast cancer. PMID:33656060
Neuronal hibernation following hippocampal demyelination. PMID:33648591
Nuclear sensing of breaks in mitochondrial DNA enhances immune surveillance. PMID:33627873
Detection of genes positively selected in Cuban Anolis lizards that naturally inhabit hot and open areas and currently thrive in urban areas. PMID:33613999
Skin Multi-Omics-Based Interactome Analysis: Integrating the Tissue and Mucus Exuded Layer for a Comprehensive Understanding of the Teleost Mucosa Functionality as Model of Study. PMID:33613538
Trans-ethnic meta-analysis identifies new loci associated with longitudinal blood pressure traits. PMID:33603002
Rapid divergence of the male reproductive proteins in the Drosophila dunni group and implications for postmating incompatibilities between species. PMID:33599779
Global variability analysis of mRNA and protein concentrations across and within human tissues. PMID:33575562
Prospective Identification of Elevated Circulating CDCP1 in Patients Years before Onset of Lung Cancer. PMID:33574093
MicroRNA Profiling of HL-1 Cardiac Cells-Derived Extracellular Vesicles. PMID:33573156
Genome assembly and annotation of the California harvester ant Pogonomyrmex californicus. PMID:33561225
SUMO pathway, blood coagulation and oxidative stress in SARS-CoV-2 infection. PMID:33558851
Genetic Diversity of Bubalus bubalis in Germany and Global Relations of Its Genetic Background. PMID:33552127
Detection of selection signatures for response to Aleutian mink disease virus infection in American mink. PMID:33536540
Regulatory Effects of CsrA in Vibrio cholerae. PMID:33531387
Radiation-induced cardiovascular disease: an overlooked role for DNA methylation? PMID:33522387
The Epstein-Barr virus deubiquitinase BPLF1 targets SQSTM1/p62 to inhibit selective autophagy. PMID:33509017
The Desmin (DES) Mutation p.A337P Is Associated with Left-Ventricular Non-Compaction Cardiomyopathy. PMID:33478057
Genomic signatures of the evolution of defence against its natural enemies in the poisonous and medicinal plant Datura stramonium (Solanaceae). PMID:33441607
Identification of loci associated with susceptibility to bovine paratuberculosis and with the dysregulation of the MECOM, eEF1A2, and U1 spliceosomal RNA expression. PMID:33432064
Capillary Electrophoresis Assessment of Plasma Protein Changes in an African Penguin (Spheniscus demersus) With Aspergillosis. PMID:33403290
Application of microRNA Database Mining in Biomarker Discovery and Identification of Therapeutic Targets for Complex Disease. PMID:33396619
Borrelia burgdorferi infection induces long-term memory-like responses in macrophages with tissue-wide consequences in the heart. PMID:33395408
Maternal immune activation in mice disrupts proteostasis in the fetal brain. PMID:33361822
Comprehensive Transcriptomic Analysis Reveals Dysregulated Competing Endogenous RNA Network in Endocrine Resistant Breast Cancer Cells. PMID:33324567
Protein Folding Stability Changes Across the Proteome Reveal Targets of Cu Toxicity in E. coli. PMID:33305953
Origin of a Giant Sex Chromosome. PMID:33300980
Transcriptome profiling revealed early vascular smooth muscle cell gene activation following focal ischemic stroke in female rats - comparisons with males. PMID:33297959
PANTHER version 16: a revised family classification, tree-based classification tool, enhancer regions and extensive API. PMID:33290554
Design and Characterization of a Novel Tool for the Antigenic Enrichment of Actinobacillus pleuropneumoniae Outer Membrane. PMID:33276526
Informatics Inference of Exercise-Induced Modulation of Brain Pathways Based on Cerebrospinal Fluid Micro-RNAs in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome. PMID:33274349
Poly(ADP-ribose) polymerase 1 in genome-wide expression control in Drosophila. PMID:33273587
Differential gene expression analysis reveals pathways important in early post-traumatic osteoarthritis in an equine model. PMID:33256611
Chemosensory-Related Gene Family Members of the Horn Fly, Haematobia irritans irritans (Diptera: Muscidae), Identified by Transcriptome Analysis. PMID:33228086
Histo-molecular differentiation of renal cancer subtypes by mass spectrometry imaging and rapid proteome profiling of formalin-fixed paraffin-embedded tumor tissue sections. PMID:33216824
Comparative proteomic analysis of dental cementum from deciduous and permanent teeth. PMID:33210734
Gene expression changes occurring at bolting time are associated with leaf senescence in Arabidopsis. PMID:33204935
Integrated transcriptome meta-analysis of pancreatic ductal adenocarcinoma and matched adjacent pancreatic tissues. PMID:33194391
Genome-Wide Assessment of DNA Methylation in Chicken Cardiac Tissue Exposed to Different Incubation Temperatures and CO2 Levels. PMID:33193638
Quantitative Structure-Mutation-Activity Relationship Tests (QSMART) model for protein kinase inhibitor response prediction. PMID:33183223
How to Make a Rodent Giant: Genomic Basis and Tradeoffs of Gigantism in the Capybara, the World's Largest Rodent. PMID:33169792
The Landscape of Pseudomonas aeruginosa Membrane-Associated Proteins. PMID:33167383
CLAVATA Signaling Ensures Reproductive Development in Plants across Thermal Environments. PMID:33157018
Transcriptome analysis of turkey (Meleagris gallopavo) reproductive tract revealed key pathways regulating spermatogenesis and post-testicular sperm maturation. PMID:33142529
Evaluation of an angiotensin Type 1 receptor blocker on the reconsolidation of fear memory. PMID:33110066
The wtf4 meiotic driver utilizes controlled protein aggregation to generate selective cell death. PMID:33108274
Human Histone Interaction Networks: An Old Concept, New Trends. PMID:33098859
Chitosan primes plant defence mechanisms against Botrytis cinerea, including expression of Avr9/Cf-9 rapidly elicited genes. PMID:33094513
Whole exome sequencing reveals pathogenic variants in MYO3A, MYO15A and COL9A3 and differential frequencies in ancestral alleles in hearing impairment genes among individuals from Cameroon. PMID:33078831
Repolarization of HSC attenuates HSCs failure in Shwachman-Diamond syndrome. PMID:33077869
Divergent genes in gerbils: prevalence, relation to GC-biased substitution, and phenotypic relevance. PMID:33076817
IL-4-BATF signaling directly modulates IL-9 producing mucosal mast cell (MMC9) function in experimental food allergy. PMID:33069715
Computational SNP Analysis and Molecular Simulation Revealed the Most Deleterious Missense Variants in the NBD1 Domain of Human ABCA1 Transporter. PMID:33066695
Distinct Pattern of Endoplasmic Reticulum Protein Processing and Extracellular Matrix Proteins in Functioning and Silent Corticotroph Pituitary Adenomas. PMID:33066652
A practical guide to mechanistic systems modeling in biology using a logic-based approach. PMID:33064138
Cocaine-related DNA methylation in caudate neurons alters 3D chromatin structure of the IRXA gene cluster. PMID:33046833
Machine learning approach to integrated endometrial transcriptomic datasets reveals biomarkers predicting uterine receptivity in cattle at seven days after estrous. PMID:33046742
Epigenetic Analysis through MSAP-NGS Coupled Technology: The Case Study of White Poplar Monoclonal Populations/Stands. PMID:33036388
The mole genome reveals regulatory rearrangements associated with adaptive intersexuality. PMID:33033216
Differential gene expression in skin RNA of horses affected with degenerative suspensory ligament desmitis. PMID:33028365
Identification of nitric oxide (NO)-responsive genes under hypoxia in tomato (Solanum lycopersicum L.) root. PMID:33020554
The Huntingtin-interacting protein SETD2/HYPB is an actin lysine methyltransferase. PMID:33008892
Proteomic profiles of unilateral cryptorchidism in pigs at different ages using MALDI-TOF mass spectrometry and in-gel digestion coupled with mass spectrometry (GeLC-MS/MS) approaches. PMID:33008399
Pancreatic Tissue Proteomics Unveils Key Proteins, Pathways, and Networks Associated with Type 1 Diabetes. PMID:33007151
An Integrative miRNA-mRNA Expression Analysis Reveals Striking Transcriptomic Similarities between Severe Equine Asthma and Specific Asthma Endotypes in Humans. PMID:32998415
Quantitative analysis of global protein stability rates in tissues. PMID:32994440
Altered Enhancer and Promoter Usage Leads to Differential Gene Expression in the Normal and Failed Human Heart. PMID:32993371
Human Fibroblasts In Vitro Exposed to 2.45 GHz Continuous and Pulsed Wave Signals: Evaluation of Biological Effects with a Multimethodological Approach. PMID:32992895
Clinical Translational Potential in Skin Wound Regeneration for Adipose-Derived, Blood-Derived, and Cellulose Materials: Cells, Exosomes, and Hydrogels. PMID:32992554
Whole transcriptome approach to evaluate the effect of aluminium hydroxide in ovine encephalon. PMID:32943671
Hypoxia inducible factor-2α importance for migration, proliferation, and self-renewal of trunk neural crest cells. PMID:32940375
DENR promotes translation reinitiation via ribosome recycling to drive expression of oncogenes including ATF4. PMID:32938922
Role of GATA3 exon 6 germline mutations in breast cancer progression in Egyptian female patients. PMID:32938228
Quantitative Protein Corona Composition and Dynamics on Carbon Nanotubes in Biological Environments. PMID:32931615
Unraveling the Genetic Basis for the Rapid Diversification of Male Genitalia between Drosophila Species. PMID:32931587
In-gel digestion coupled with mass spectrometry (GeLC-MS/MS)-based salivary proteomic profiling of canine oral tumors. PMID:32928212
Label-free quantitative proteomic analysis of gingival crevicular fluid to identify potential early markers for root resorption. PMID:32917196
iTRAQ‑based proteomic analysis reveals potential regulatory networks in dust mite‑related asthma treated with subcutaneous allergen immunotherapy. PMID:32901873
A tree frog (Boana pugnax) dataset of skin transcriptome for the identification of biomolecules with potential antimicrobial activities. PMID:32875010
Neurotoxic microglia promote TDP-43 proteinopathy in progranulin deficiency. PMID:32866962
Transcriptomic and proteomic signatures of stemness and differentiation in the colon crypt. PMID:32814826
The Coevolution of Cellularity and Metabolism Following the Origin of Life. PMID:32809045
Changes in the plasma microvesicle proteome during the ovarian hyperstimulation phase of assisted reproductive technology. PMID:32788624
EST-SNP Study of Olea europaea L. Uncovers Functional Polymorphisms between Cultivated and Wild Olives. PMID:32785094
Hydroxytyrosol as a Promising Ally in the Treatment of Fibromyalgia. PMID:32784915
Applications of Proteomic Tools to Study Insect Vector-Plant Virus Interactions. PMID:32784674
Altered miRNAs Expression Correlates With Gastroenteropancreatic Neuroendocrine Tumors Grades. PMID:32766159
Transcriptomic analysis reveals differential gene expression, alternative splicing, and novel exons during mouse trophoblast stem cell differentiation. PMID:32762732
Bacterial Evolution in High-Osmolarity Environments. PMID:32753494
An interspecies translation model implicates integrin signaling in infliximab-resistant inflammatory bowel disease. PMID:32753478
Cell death and survival pathways in Alzheimer's disease: an integrative hypothesis testing approach utilizing -omic data sets. PMID:32745806
Genome-Wide Screen for Context-Dependent Tumor Suppressors Identified Using in Vivo Models for Neoplasia in Drosophila. PMID:32737065
Regional sequence expansion or collapse in heterozygous genome assemblies. PMID:32735589
Immune network dysregulation precedes clinical diagnosis of asthma. PMID:32732938
The Expression of Cold-Inducible RNA-Binding Protein mRNA in Sow Genital Tract Is Modulated by Natural Mating, But Not by Seminal Plasma. PMID:32727091
Gcn2 eIF2α kinase mediates combinatorial translational regulation through nucleotide motifs and uORFs in target mRNAs. PMID:32710633
Improved Reference Genome for Cyclotella cryptica CCMP332, a Model for Cell Wall Morphogenesis, Salinity Adaptation, and Lipid Production in Diatoms (Bacillariophyta). PMID:32709619
Comparative proteomic analysis uncovers potential biomarkers involved in the anticancer effect of Scutellarein in human gastric cancer cells. PMID:32705238
Analysis of Cytoplasmic and Secreted Proteins of Staphylococcus aureus Revealed Adaptive Metabolic Homeostasis in Response to Changes in the Environmental Conditions Representative of the Human Wound Site. PMID:32698515
Tiotropium is Predicted to be a Promising Drug for COVID-19 Through Transcriptome-Based Comprehensive Molecular Pathway Analysis. PMID:32698440
Genomics of Heat Tolerance in Reproductive Performance Investigated in Four Independent Maternal Lines of Pigs. PMID:32695139
BRG1 Loss Predisposes Lung Cancers to Replicative Stress and ATR Dependency. PMID:32690724
The power and limitations of gene expression pathway analyses toward predicting population response to environmental stressors. PMID:32684953
Computational analysis of TP53 mutational landscape unveils key prognostic signatures and distinct pathobiological pathways in head and neck squamous cell cancer. PMID:32684626
Unique transcriptional changes in coagulation cascade genes in SARS-CoV-2-infected lung epithelial cells: A potential factor in COVID-19 coagulopathies. PMID:32676594
p190A RhoGAP induces CDH1 expression and cooperates with E-cadherin to activate LATS kinases and suppress tumor cell growth. PMID:32641858
Transcriptome Analyses of Candida albicans Biofilms, Exposed to Arachidonic Acid and Fluconazole, Indicates Potential Drug Targets. PMID:32631950
Genetic factors for short life span associated with evolution of the loss of flight ability. PMID:32607209
Fulvic acid increases forage legume growth inducing preferential up-regulation of nodulation and signalling-related genes. PMID:32599619
Tfam Knockdown Results in Reduction of mtDNA Copy Number, OXPHOS Deficiency and Abnormalities in Zebrafish Embryos. PMID:32596237
The MiDAC histone deacetylase complex is essential for embryonic development and has a unique multivalent structure. PMID:32591534
Expansions of chemosensory gene orthologs among selected tsetse fly species and their expressions in Glossina morsitans morsitans tsetse fly. PMID:32589659
Extracellular Vesicles of Human Periodontal Ligament Stem Cells Contain MicroRNAs Associated to Proto-Oncogenes: Implications in Cytokinesis. PMID:32582296
Time-series proteomic study of the response of HK-2 cells to hyperglycemic, hypoxic diabetic-like milieu. PMID:32579601
The ATGL lipase cooperates with ABHD5 to mobilize lipids for hepatitis C virus assembly. PMID:32542055
Antigenic membrane proteins of virulent variant of Entamoeba histolytica HM-1:IMSS. PMID:32536281
Studies of human twins reveal genetic variation that affects dietary fat perception. PMID:32516399
Single-Cell Transcriptomics Analysis Identifies Nuclear Protein 1 as a Regulator of Docetaxel Resistance in Prostate Cancer Cells. PMID:32513898
The Wnt non-canonical signaling modulates cabazitaxel sensitivity in prostate cancer cells. PMID:32484838
The Msi1-mTOR pathway drives the pathogenesis of mammary and extramammary Paget's disease. PMID:32457396
Comparative analysis of MACROD1, MACROD2 and TARG1 expression, localisation and interactome. PMID:32427867
Detecting qualitative changes in biological systems. PMID:32424123
The emerging roles of WBP2 oncogene in human cancers. PMID:32393834
Targeting Pyruvate Carboxylase by a Small Molecule Suppresses Breast Cancer Progression. PMID:32382484
Asian Zika Virus Isolate Significantly Changes the Transcriptional Profile and Alternative RNA Splicing Events in a Neuroblastoma Cell Line. PMID:32380717
Genomic competition for noise reduction shaped evolutionary landscape of mir-4673. PMID:32376854
Diversification of piRNAs expressed in PGCs and somatic cells during embryonic gonadal development. PMID:32375541
Unmasking Intra-tumoral Heterogeneity and Clonal Evolution in NF1-MPNST. PMID:32369930
Identifying Therapies to Combat Epithelial Mesenchymal Plasticity-Associated Chemoresistance to Conventional Breast Cancer Therapies Using An shRNA Library Screen. PMID:32365878
Proteomic profiling of Serratia marcescens by high-resolution mass spectrometry. PMID:32363156
Proteomic variations after short-term heat shock treatment reveal differentially expressed proteins involved in early microspore embryogenesis in cabbage (Brassica oleracea). PMID:32337101
Modeling Basins of Attraction for Breast Cancer Using Hopfield Networks. PMID:32318098
Structural and functional properties of proteins interacting with small heat shock proteins. PMID:32314314
Old Mice Have Less Transcriptional Activation But Similar Periosteal Cell Proliferation Compared to Young-Adult Mice in Response to in vivo Mechanical Loading. PMID:32311160
High-Throughput Sequencing Identifies 3 Novel Susceptibility Genes for Hereditary Melanoma. PMID:32276436
IL-6 blockade reverses bone marrow failure induced by human acute myeloid leukemia. PMID:32269167
Mesenchymal Stem Cell Derived Extracellular Vesicles Ameliorate Kidney Injury in Aristolochic Acid Nephropathy. PMID:32266268
Patterns of gene evolution following duplications and speciations in vertebrates. PMID:32266119
SMYD2 suppresses APC2 expression to activate the Wnt/β-catenin pathway and promotes epithelial-mesenchymal transition in colorectal cancer. PMID:32266106
A comprehensive analysis of sialolith proteins and the clinical implications. PMID:32265614
Prediction of cardiovascular risk in preterm neonates through urinary proteomics: An exploratory study. PMID:32258784
Genetic Deletion of Zebrafish Rab28 Causes Defective Outer Segment Shedding, but Not Retinal Degeneration. PMID:32258030
Age-Associated DNA Methylation Patterns Are Shared Between the Hippocampus and Peripheral Blood Cells. PMID:32211019
KANK2 Links αVβ5 Focal Adhesions to Microtubules and Regulates Sensitivity to Microtubule Poisons and Cell Migration. PMID:32195252
Genome-wide association meta-analysis of corneal curvature identifies novel loci and shared genetic influences across axial length and refractive error. PMID:32193507
Time course regulatory analysis based on paired expression and chromatin accessibility data. PMID:32188700
Antisense oligonucleotide treatment produces a type I interferon response that protects against diet-induced obesity. PMID:32180554
Revisiting Parameter Estimation in Biological Networks: Influence of Symmetries. PMID:32175871
Circular RNA expression profile in blood according to ischemic stroke etiology. PMID:32175077
A Novel System for Functional Determination of Variants of Uncertain Significance using Deep Convolutional Neural Networks. PMID:32144301
Alveolar Macrophage Chromatin Is Modified to Orchestrate Host Response to Mycobacterium bovis Infection. PMID:32117424
Transcriptomic Features of T Cell-Barren Tumors Are Conserved Across Diverse Tumor Types. PMID:32117236
In silico analysis of a novel causative mutation in Cadherin23 gene identified in an Omani family with hearing loss. PMID:32115674
Aberrant Development Corrected in Adult-Onset Huntington's Disease iPSC-Derived Neuronal Cultures via WNT Signaling Modulation. PMID:32109367
The Transcriptome of Pig Spermatozoa, and Its Role in Fertility. PMID:32106598
Interactome of vertebrate GAF/ThPOK reveals its diverse functions in gene regulation and DNA repair. PMID:32098917
Cellular Heterogeneity and Lineage Restriction during Mouse Digit Tip Regeneration at Single-Cell Resolution. PMID:32097654
EPSIN1 Modulates the Plasma Membrane Abundance of FLAGELLIN SENSING2 for Effective Immune Responses. PMID:32094305
Predicting clinical benefit of immunotherapy by antigenic or functional mutations affecting tumour immunogenicity. PMID:32075964
Association of functional variants and protein-to-protein physical interactions of human MutY homolog linked with familial adenomatous polyposis and colorectal cancer syndrome. PMID:32072083
Proteome data to explore the axolotl limb regeneration capacity at neotenic and metamorphic stages. PMID:32055664
Effects of gamma-aminobutyric acid and piperine on gene regulation in pig kidney epithelial cell lines. PMID:32054169
The quail genome: insights into social behaviour, seasonal biology and infectious disease response. PMID:32050986
TGF-ß1 Induces Changes in the Energy Metabolism of White Adipose Tissue-Derived Human Adult Mesenchymal Stem/Stromal Cells In Vitro. PMID:32046088
Active nuclear import of the deacetylase Sirtuin-2 is controlled by its C-terminus and importins. PMID:32042025
Defining the Adult Neural Stem Cell Niche Proteome Identifies Key Regulators of Adult Neurogenesis. PMID:32032526
Exosomes mediate sensory hair cell protection in the inner ear. PMID:32027617
RNA-Seq reveals novel genes and pathways associated with hypoxia duration and tolerance in tomato root. PMID:32015352
Avian Pathogenic Escherichia coli (APEC) Strain-Dependent Immunomodulation of Respiratory Granulocytes and Mononuclear Phagocytes in CSF1R-Reporter Transgenic Chickens. PMID:31998322
Selected microRNAs Increase Synaptic Resilience to the Damaging Binding of the Alzheimer's Disease Amyloid Beta Oligomers. PMID:31997075
Functional and population genetic features of copy number variations in two dairy cattle populations. PMID:31992181
A novel role of tumor suppressor ZMYND8 in inducing differentiation of breast cancer cells through its dual-histone binding function. PMID:31965980
Quantitative Characterization of the Neuropeptide Level Changes in Dorsal Horn and Dorsal Root Ganglia Regions of the Murine Itch Models. PMID:31957451
Dynamic changes in cis-regulatory occupancy by Six1 and its cooperative interactions with distinct cofactors drive lineage-specific gene expression programs during progressive differentiation of the auditory sensory epithelium. PMID:31956913
PTPN13 induces cell junction stabilization and inhibits mammary tumor invasiveness. PMID:31938048
Duodenum Intestine-Chip for preclinical drug assessment in a human relevant model. PMID:31933478
Fine-mapping of 150 breast cancer risk regions identifies 191 likely target genes. PMID:31911677
Sensitive detection of EBV microRNAs across cancer spectrum reveals association with decreased survival in adult acute myelocytic leukemia. PMID:31889055
Prediction and Structural Comparison of Deleterious Coding Nonsynonymous Single Nucleotide Polymorphisms (nsSNPs) in Human LEP Gene Associated with Obesity. PMID:31871931
Knowledge Base Commons (KBCommons) v1.1: a universal framework for multi-omics data integration and biological discoveries. PMID:31856718
Expression Profile of the Chromosome 14 MicroRNA Cluster (C14MC) Ortholog in Equine Maternal Circulation throughout Pregnancy and Its Potential Implications. PMID:31847075
A genome-scale CRISPR/Cas9 knockout screening reveals SH3D21 as a sensitizer for gemcitabine. PMID:31844142
Evolutionarily novel genes are expressed in transgenic fish tumors and their orthologs are involved in development of progressive traits in humans. PMID:31827597
Regulation of Tumor Initiation by the Mitochondrial Pyruvate Carrier. PMID:31813825
Determining the pathogenicity of CFTR missense variants: Multiple comparisons of in silico predictors and variant annotation databases. PMID:31808782
Systems pharmacology based approach to investigate the in-vivo therapeutic efficacy of Albizia lebbeck (L.) in experimental model of Parkinson's disease. PMID:31805998
Effects of culture condition on epigenomic profiles of brain tumor cells. PMID:31799379
Interleukin-22 orchestrates a pathological endoplasmic reticulum stress response transcriptional programme in colonic epithelial cells. PMID:31792136
Genomic Divergence in Swedish Warmblood Horses Selected for Equestrian Disciplines. PMID:31783652
A Comprehensive Analysis of Runs of Homozygosity of Eleven Cattle Breeds Representing Different Production Types. PMID:31775271
Comparative co-expression network analysis extracts the SlHSP70 gene affecting to shoot elongation of tomato. PMID:31768116
JASPer controls interphase histone H3S10 phosphorylation by chromosomal kinase JIL-1 in Drosophila. PMID:31767855
Exploratory analysis of transposable elements expression in the C. elegans early embryo. PMID:31757208
ENCORE: A Visualization Tool for Insight into Circadian Omics. PMID:31754663
The Firre locus produces a trans-acting RNA molecule that functions in hematopoiesis. PMID:31723143
MC1R and KIT Haplotypes Associate With Pigmentation Phenotypes of North American Yak (Bos grunniens). PMID:31714577
Improved Draft Genome Sequence of Microbacterium sp. Strain LKL04, a Bacterial Endophyte Associated with Switchgrass Plants. PMID:31699756
Notch1 signaling in NOTCH1-mutated mantle cell lymphoma depends on Delta-Like ligand 4 and is a potential target for specific antibody therapy. PMID:31676012
PACAP and Other Neuropeptide Targets Link Chronic Migraine and Opioid-induced Hyperalgesia in Mouse Models. PMID:31649062
Cis-regulatory basis of sister cell type divergence in the vertebrate retina. PMID:31633482
Quantitative Proteome Profiling of Coxiella burnetii Reveals Major Metabolic and Stress Differences Under Axenic and Cell Culture Cultivation. PMID:31620097
Identifying significantly impacted pathways: a comprehensive review and assessment. PMID:31597578
Anti-Inflammatory Effects of HDL (High-Density Lipoprotein) in Macrophages Predominate Over Proinflammatory Effects in Atherosclerotic Plaques. PMID:31578081
Catalytically inactive Dnmt3b rescues mouse embryonic development by accessory and repressive functions. PMID:31558711
Differential Gene Expression in Articular Cartilage and Subchondral Bone of Neonatal and Adult Horses. PMID:31557843
Population Genomics of an Obligately Halophilic Basidiomycete Wallemia ichthyophaga. PMID:31551960
Multi-Omics Analysis of Fatty Alcohol Production in Engineered Yeasts Saccharomyces cerevisiae and Yarrowia lipolytica. PMID:31543895
Signatures of selection in the genome of Swedish warmblood horses selected for sport performance. PMID:31533613
An integrated genome-wide multi-omics analysis of gene expression dynamics in the preimplantation mouse embryo. PMID:31527703
Proteogenomic Network Analysis of Context-Specific KRAS Signaling in Mouse-to-Human Cross-Species Translation. PMID:31521603
Tox4 modulates cell fate reprogramming. PMID:31519808
Glycogen storage diseases: Twenty-seven new variants in a cohort of 125 patients. PMID:31508908
Wnt signaling regulates trans-differentiation of stem cell like type 2 alveolar epithelial cells to type 1 epithelial cells. PMID:31492143
Identification of Molecular Targets of Dietary Grape-Mediated Chemoprevention of Ultraviolet B Skin Carcinogenesis: A Comparative Quantitative Proteomics Analysis. PMID:31487184
The Role of Extracellular Matrix Expression, ERK1/2 Signaling and Cell Cohesiveness for Cartilage Yield from iPSCs. PMID:31480758
Multidimensional Predictors of Susceptibility and Resilience to Social Defeat Stress. PMID:31466563
The Effects of Sindbis Viral Vectors on Neuronal Function. PMID:31440143
Functional analysis of a novel G87V TNFRSF1A mutation in patients with TNF receptor-associated periodic syndrome. PMID:31429073
Dynamic Enhancer DNA Methylation as Basis for Transcriptional and Cellular Heterogeneity of ESCs. PMID:31422875
Betaglycan drives the mesenchymal stromal cell osteogenic program and prostate cancer-induced osteogenesis. PMID:31409900
Fragile X mental retardation protein protects against tumour necrosis factor-mediated cell death and liver injury. PMID:31409605
Evaluation of the usefulness of saliva for DNA methylation analysis in cohort studies. PMID:31393092
A Myt1 family transcription factor defines neuronal fate by repressing non-neuronal genes. PMID:31386623
Impact of Heat Shock Protein 90 Inhibition on the Proteomic Profile of Lung Adenocarcinoma as Measured by Two-Dimensional Electrophoresis Coupled with Mass Spectrometry. PMID:31370342
Whole genome sequence and de novo assembly revealed genomic architecture of Indian Mithun (Bos frontalis). PMID:31357931
Ribosome profiling of selenoproteins in vivo reveals consequences of pathogenic Secisbp2 missense mutations. PMID:31350336
TAF1, associated with intellectual disability in humans, is essential for embryogenesis and regulates neurodevelopmental processes in zebrafish. PMID:31341187
Neonatal Intermittent Hypoxia Induces Lasting Sex-Specific Augmentation of Rat Microglial Cytokine Expression. PMID:31333645
Simultaneous Enrichment Analysis of all Possible Gene-sets: Unifying Self-Contained and Competitive Methods. PMID:31297505
Assessing predictions on fitness effects of missense variants in calmodulin. PMID:31283071
Landscape of Overlapping Gene Expression in the Equine Placenta. PMID:31269762
Hcr1/eIF3j Is a 60S Ribosomal Subunit Recycling Accessory Factor In Vivo. PMID:31269449
Glial α-synuclein promotes neurodegeneration characterized by a distinct transcriptional program in vivo. PMID:31267577
Proteomic analysis of the effect of the polyphenol pentagalloyl glucose on proteins involved in neurodegenerative diseases in activated BV‑2 microglial cells. PMID:31257500
Many rice genes are differentially spliced between roots and shoots but cytokinin has minimal effect on splicing. PMID:31245776
Dynamic adaptation of mesenchymal stem cell physiology upon exposure to surface micropatterns. PMID:31235713
Atlas of Subcellular RNA Localization Revealed by APEX-Seq. PMID:31230715
Altered keratinocyte differentiation is an early driver of keratin mutation-based palmoplantar keratoderma. PMID:31220272
Shigella promotes major alteration of gut epithelial physiology and tissue invasion by shutting off host intracellular transport. PMID:31209035
DNA methylation profiling allows for characterization of atrial and ventricular cardiac tissues and hiPSC-CMs. PMID:31186048
Spatial proteomics reveal that the protein phosphatase PTP1B interacts with and may modify tyrosine phosphorylation of the rhomboid protease RHBDL4. PMID:31177093
Aberrant NFATc1 signaling counteracts TGFβ-mediated growth arrest and apoptosis induction in pancreatic cancer progression. PMID:31171768
Genomic Evidence of Recombination in the Basidiomycete Wallemia mellicola. PMID:31167502
Differential gene expression in relation to mating system in Peromyscine rodents. PMID:31161013
Molecular profiling of anastatic cancer cells: potential role of the nuclear export pathway. PMID:31147963
New roles for the de-ubiquitylating enzyme OTUD4 in an RNA-protein network and RNA granules. PMID:31138677
Conventionally used reference genes are not outstanding for normalization of gene expression in human cancer research. PMID:31138119
Proteomic Analysis of MeJa-Induced Defense Responses in Rice against Wounding. PMID:31121967
Fifty Aureobasidium pullulans genomes reveal a recombining polyextremotolerant generalist. PMID:31112354
Proteomic insight into the pathogenesis of CAPN5-vitreoretinopathy. PMID:31110225
Proteomics Analysis of Urine to Examine Physical Effects of Warm Nano Mist Sauna Bathing. PMID:31109144
Genetics of cocaine and methamphetamine consumption and preference in Drosophila melanogaster. PMID:31107875
Multi-level Modulation of Light Signaling by GIGANTEA Regulates Both the Output and Pace of the Circadian Clock. PMID:31105011
Therapy-Induced MHC I Ligands Shape Neo-Antitumor CD8 T Cell Responses during Oncolytic Virus-Based Cancer Immunotherapy. PMID:31095916
Proteomic Profiling of Exosomes Derived from Plasma of HIV-Infected Alcohol Drinkers and Cigarette Smokers. PMID:31065972
CAMK2-Dependent Signaling in Neurons Is Essential for Survival. PMID:31064859
Novel transcriptional responses to heat revealed by turning up the heat at night. PMID:31062216
Genetically Distinct Behavioral Modules Underlie Natural Variation in Thermal Performance Curves. PMID:31048400
Porcine Epidemic Diarrhea Virus (PEDV) ORF3 Interactome Reveals Inhibition of Virus Replication by Cellular VPS36 Protein. PMID:31022991
Placental DNA methylation levels at CYP2E1 and IRS2 are associated with child outcome in a prospective autism study. PMID:31009952
Analysis of cyclin E co-expression genes reveals nuclear transcription factor Y subunit alpha is an oncogene in gastric cancer. PMID:30993263
Tracing the phylogenetic history of the Crl regulon through the Bacteria and Archaea genomes. PMID:30991941
An inducible model of human amylin overexpression reveals diverse transcriptional changes. PMID:30974231
A genome-wide association study of tramadol metabolism from post-mortem samples. PMID:30971809
Transcriptional changes in response to ketamine ester-analogs SN 35210 and SN 35563 in the rat brain. PMID:30971208
Physiological profile of undifferentiated bovine blastocyst-derived trophoblasts. PMID:30952696
Effects of early social deprivation on epigenetic statuses and adaptive behavior of young children: A study based on a cohort of institutionalized infants and toddlers. PMID:30913238
Gene expression imputation across multiple brain regions provides insights into schizophrenia risk. PMID:30911161
The First Report of Polymorphisms and Genetic Features of the prion-like Protein Gene (PRND) in a Prion Disease-Resistant Animal, Dog. PMID:30897750
Hawaiian picture-winged Drosophila exhibit adaptive population divergence along a narrow climatic gradient on Hawaii Island. PMID:30891191
O-GlcNAcylation Enhances Double-Strand Break Repair, Promotes Cancer Cell Proliferation, and Prevents Therapy-Induced Senescence in Irradiated Tumors. PMID:30885991
Powerful gene set analysis in GWAS with the Generalized Berk-Jones statistic. PMID:30875371
Meta-analysis suggests evidence of novel stress-related pathway components in Orsay virus - Caenorhabditis elegans viral model. PMID:30867481
A comparison between the abdominal and femoral adipose tissue proteome of overweight and obese women. PMID:30862933
G-protein Gα13 functions as a cytoskeletal and mitochondrial regulator to restrain osteoclast function. PMID:30862896
The histone methyltransferase G9a regulates tolerance to oxidative stress-induced energy consumption. PMID:30860988
A Study into the ADP-Ribosylome of IFN-γ-Stimulated THP-1 Human Macrophage-like Cells Identifies ARTD8/PARP14 and ARTD9/PARP9 ADP-Ribosylation. PMID:30848916
Mammary Gland Transcriptome and Proteome Modifications by Nutrient Restriction in Early Lactation Holstein Cows Challenged with Intra-Mammary Lipopolysaccharide. PMID:30845783
Making Sense of the Epigenome Using Data Integration Approaches. PMID:30837884
Cell lineage inference from SNP and scRNA-Seq data. PMID:30820578
Advancing Personalized Medicine Through the Application of Whole Exome Sequencing and Big Data Analytics. PMID:30809243
Protocol Update for large-scale genome and gene function analysis with the PANTHER classification system (v.14.0). PMID:30804569
Genomic evidence for shared common ancestry of East African hunting-gathering populations and insights into local adaptation. PMID:30782801
CirGO: an alternative circular way of visualising gene ontology terms. PMID:30777018
Protein stability of p53 targets determines their temporal expression dynamics in response to p53 pulsing. PMID:30745421
Reduced mitochondrial fusion and Huntingtin levels contribute to impaired dendritic maturation and behavioral deficits in Fmr1-mutant mice. PMID:30742117
Smp38 MAP Kinase Regulation in Schistosoma mansoni: Roles in Survival, Oviposition, and Protection Against Oxidative Stress. PMID:30733716
Global host molecular perturbations upon in situ loss of bacterial endosymbionts in the deep-sea mussel Bathymodiolus azoricus assessed using proteomics and transcriptomics. PMID:30727955
Comparative transcriptome analysis of mammary epithelial cells at different stages of lactation reveals wide differences in gene expression and pathways regulating milk synthesis between Jersey and Kashmiri cattle. PMID:30721247
Cyclin D1 integrates G9a-mediated histone methylation. PMID:30718920
Exploring the genetics of trotting racing ability in horses using a unique Nordic horse model. PMID:30717660
The translational regulator FMRP controls lipid and glucose metabolism in mice and humans. PMID:30686771
Synthetic lethality guiding selection of drug combinations in ovarian cancer. PMID:30682083
Complementary Proteomics, Genomics approaches identifies potential pathogenicity/virulence factors in Tilletia indica induced under the influence of host factor. PMID:30679765
Mycophenolate mofetil reduces STAT3 phosphorylation in systemic lupus erythematosus patients. PMID:30674728
Inhibition of monocyte-like cell extravasation protects from neurodegeneration in DBA/2J glaucoma. PMID:30670050
Comparative Analysis of Developmental Transcriptome Maps of Arabidopsis thaliana and Solanum lycopersicum. PMID:30650673
Extracellular ATP Shapes a Defense-Related Transcriptome Both Independently and along with Other Defense Signaling Pathways. PMID:30630869
Chromatin changes in Anopheles gambiae induced by Plasmodium falciparum infection. PMID:30616642
Innate immunity in the simplest animals - placozoans. PMID:30611207
LXR Suppresses Inflammatory Gene Expression and Neutrophil Migration through cis-Repression and Cholesterol Efflux. PMID:30590048
A Transcriptome Study of Progeroid Neurocutaneous Syndrome Reveals POSTN As a New Element in Proline Metabolic Disorder. PMID:30574417
Kinetics of the chromosome 14 microRNA cluster ortholog and its potential role during placental development in the pregnant mare. PMID:30572819
Computational Methods for the Pharmacogenetic Interpretation of Next Generation Sequencing Data. PMID:30564131
Synthetic lethal combinations of low-toxicity drugs for breast cancer identified in silico by genetic screens in yeast. PMID:30555636
SIN-3 as a key determinant of lifespan and its sex dependent differential role on healthspan in Caenorhabditis elegans. PMID:30541942
Coordinated regulation of transcription by CcpA and the Staphylococcus aureus two-component system HptRS. PMID:30540769
Time-resolved interaction proteomics of the GIGANTEA protein under diurnal cycles in Arabidopsis. PMID:30536871
Integrated In Vivo Quantitative Proteomics and Nutrient Tracing Reveals Age-Related Metabolic Rewiring of Pancreatic β Cell Function. PMID:30517875
Proteomic profiling of senescent human diploid fibroblasts treated with gamma-tocotrienol. PMID:30497457
Forced turnover of aged microglia induces an intermediate phenotype but does not rebalance CNS environmental cues driving priming to immune challenge. PMID:30477578
NeVOmics: An Enrichment Tool for Gene Ontology and Functional Network Analysis and Visualization of Data from OMICs Technologies. PMID:30477135
Proteome Investigation of Rat Lungs subjected to Ex Vivo Perfusion (EVLP). PMID:30467300
ProSave: an application for restoring quantitative data to manipulated subsets of protein lists. PMID:30459825
Toward the precision breast cancer survival prediction utilizing combined whole genome-wide expression and somatic mutation analysis. PMID:30454048
Large-Scale Analyses of Site-Specific Evolutionary Rates across Eukaryote Proteomes Reveal Confounding Interactions between Intrinsic Disorder, Secondary Structure, and Functional Domains. PMID:30441862
Global impacts of chromosomal imbalance on gene expression in Arabidopsis and other taxa. PMID:30429332
Promotion of tumor progression and cancer stemness by MUC15 in thyroid cancer via the GPCR/ERK and integrin-FAK signaling pathways. PMID:30420637
The crowns have eyes: multiple opsins found in the eyes of the crown-of-thorns starfish Acanthaster planci. PMID:30419810
Biofilm-induced profiles of immune response gene expression by oral epithelial cells. PMID:30407731
PANTHER version 14: more genomes, a new PANTHER GO-slim and improvements in enrichment analysis tools. PMID:30407594
Molecular Signature of Aluminum Hydroxide Adjuvant in Ovine PBMCs by Integrated mRNA and microRNA Transcriptome Sequencing. PMID:30405610
Combining QTL mapping with transcriptome and metabolome profiling reveals a possible role for ABA signaling in resistance against the cabbage whitefly in cabbage. PMID:30399182
Behavior-dependent cis regulation reveals genes and pathways associated with bower building in cichlid fishes. PMID:30397142
Induction of apoptosis in ovarian cancer cells by miR-493-3p directly targeting AKT2, STK38L, HMGA2, ETS1 and E2F5. PMID:30392041
The gut microbiome participates in transgenerational inheritance of low-temperature responses in Drosophila melanogaster. PMID:30372516
Ancestral Genomes: a resource for reconstructed ancestral genes and genomes across the tree of life. PMID:30371900
Determinants of promoter and enhancer transcription directionality in metazoans. PMID:30367057
Global expression profiling and pathway analysis in two different population groups in relation to high altitude. PMID:30341547
Transcriptome profiling of rubber tree (Hevea brasiliensis) discovers candidate regulators of the cold stress response. PMID:30315521
Increased levels of circulating MMP3 correlate with severe rejection in face transplantation. PMID:30297859
PRP4KA, a Putative Spliceosomal Protein Kinase, Is Important for Alternative Splicing and Development in Arabidopsis thaliana. PMID:30297453
Bone protection by inhibition of microRNA-182. PMID:30291236
Proteome and transcriptome profiling of equine myofibrillar myopathy identifies diminished peroxiredoxin 6 and altered cysteine metabolic pathways. PMID:30289745
IL-6 augments IL-4-induced polarization of primary human macrophages through synergy of STAT3, STAT6 and BATF transcription factors. PMID:30288360
In Search of Biomarkers for Pathogenesis and Control of Leishmaniasis by Global Analyses of Leishmania-Infected Macrophages. PMID:30283744
Personalized Proteomics for Precision Health: Identifying Biomarkers of Vitreoretinal Disease. PMID:30271679
Differentiation enhances Zika virus infection of neuronal brain cells. PMID:30266962
Differential Expression of Keratinocyte-Derived Extracellular Vesicle Mirnas Discriminate Exosomes From Apoptotic Bodies and Microvesicles. PMID:30258405
Time-resolved proteomics of adenovirus infected cells. PMID:30252905
Identification of a 3'-Untranslated Genetic Variant of RARB Associated With Carotid Intima-Media Thickness in Rheumatoid Arthritis: A Genome-Wide Association Study. PMID:30251476
Transcriptome profiling of the cardiac neural crest reveals a critical role for MafB. PMID:30236445
Gene regulation underlies environmental adaptation in house mice. PMID:30194096
MKK6 Functions in Two Parallel MAP Kinase Cascades in Immune Signaling. PMID:30185442
The first report of polymorphisms and genetic characteristics of the prion protein gene (PRNP) in horses. PMID:30165784
Systematic Dissection of the Evolutionarily Conserved WetA Developmental Regulator across a Genus of Filamentous Fungi. PMID:30131357
Co-expression of CD21L and IL17A defines a subset of rheumatoid synovia, characterised by large lymphoid aggregates and high inflammation. PMID:30114200
Non-Coding Transcriptome Maps across Twenty Tissues of the Korean Black Chicken, Yeonsan Ogye. PMID:30103450
Postsynaptic Proteome of Non-Demented Individuals with Alzheimer's Disease Neuropathology. PMID:30103319
Choline ameliorates adult learning deficits and reverses epigenetic modification of chromatin remodeling factors related to adolescent nicotine exposure. PMID:30099202
Programmed cell removal by calreticulin in tissue homeostasis and cancer. PMID:30097573
Human Liver Stem Cell-Derived Extracellular Vesicles Prevent Aristolochic Acid-Induced Kidney Fibrosis. PMID:30072992
In silico analysis of SLC3A1 and SLC7A9 mutations in Iranian patients with Cystinuria. PMID:30069816
Analysis of the Long-Lived Responses Induced by Immunostimulants and Their Effects on a Viral Infection in Zebrafish (Danio rerio). PMID:30038625
An integrative network-based approach to identify novel disease genes and pathways: a case study in the context of inflammatory bowel disease. PMID:30005591
Proteomic analysis of canine oral tumor tissues using MALDI-TOF mass spectrometry and in-gel digestion coupled with mass spectrometry (GeLC MS/MS) approaches. PMID:30001383
Overview of inactivating mutations in the protein-coding genome of the mouse reference strain C57BL/6J. PMID:29997285
Genetic selection of athletic success in sport-hunting dogs. PMID:29970415
Comprehensive ADP-ribosylome analysis identifies tyrosine as an ADP-ribose acceptor site. PMID:29954836
Genome data uncover four synergistic key regulators for extremely small body size in horses. PMID:29940849
Fate of uptaken host proteins in Taenia solium and Taenia crassiceps cysticerci. PMID:29921579
Systematic study of the dynamics and half-lives of newly synthesized proteins in human cells. PMID:29910897
Proteomic Analysis of Avian Influenza A (H7N9) Patients within a Family Cluster. PMID:29910565
MiR-744-5p inducing cell death by directly targeting HNRNPC and NFIX in ovarian cancer cells. PMID:29899543
Transcriptional profiling of antioxidant defense system and heat shock protein (Hsp) families in the cadmium- and copper-exposed marine ciliate Euplotes crassu. PMID:29892903
Transcriptional analyses provide new insight into the late-stage immune response of a diseased Caribbean coral. PMID:29892394
Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci. PMID:29892016
Two novel mutations in the GAN gene causing giant axonal neuropathy. PMID:29876741
Immune gene expression in kidney biopsies of lupus nephritis patients at diagnosis and at renal flare. PMID:29800348
Integrated proteomics, genomics, metabolomics approaches reveal oxalic acid as pathogenicity factor in Tilletia indica inciting Karnal bunt disease of wheat. PMID:29777151
Quantification of HLA-DM-Dependent Major Histocompatibility Complex of Class II Immunopeptidomes by the Peptide Landscape Antigenic Epitope Alignment Utility. PMID:29774024
ENTPRISE-X: Predicting disease-associated frameshift and nonsense mutations. PMID:29723276
Guanine Limitation Results in CodY-Dependent and -Independent Alteration of Staphylococcus aureus Physiology and Gene Expression. PMID:29712876
Genome-wide RNAi Screening to Identify Host Factors That Modulate Oncolytic Virus Therapy. PMID:29683442
Mechanical strain induced phospho-proteomic signaling in uterine smooth muscle cells. PMID:29661501
Shewanella oneidensis MR-1 Utilizes both Sodium- and Proton-Pumping NADH Dehydrogenases during Aerobic Growth. PMID:29654176
Inflammatory pathways are central to posterior cerebrovascular artery remodelling prior to the onset of congenital hypertension. PMID:29651914
BAG3 promotes tumour cell proliferation by regulating EGFR signal transduction pathways in triple negative breast cancer. PMID:29644001
Association of leptin, toll-like receptor 4, and chemokine receptor of interleukin 8 C-X-C motif single nucleotide polymorphisms with fertility traits in Czech Fleckvieh cattle. PMID:29642663
PARP1 depletion induces RIG-I-dependent signaling in human cancer cells. PMID:29590171
SUMOylome Profiling Reveals a Diverse Array of Nuclear Targets Modified by the SUMO Ligase SIZ1 during Heat Stress. PMID:29588388
Systematic Characterization of Stress-Induced RNA Granulation. PMID:29576526
Integrative proteomics in prostate cancer uncovers robustness against genomic and transcriptomic aberrations during disease progression. PMID:29563510
Allopregnanolone Alters the Gene Expression Profile of Human Glioblastoma Cells. PMID:29543748
Generalising better: Applying deep learning to integrate deleteriousness prediction scores for whole-exome SNV studies. PMID:29538399
SMILE: a novel procedure for subcellular module identification with localisation expansion. PMID:29533218
STAT3 precedes HIF1α transcriptional responses to oxygen and oxygen and glucose deprivation in human brain pericytes. PMID:29518129
RecQ Helicases Function in Development, DNA Repair, and Gene Targeting in Physcomitrella patens. PMID:29514942
Evaluation of involved proteins in colon adenocarcinoma: an interactome analysis. PMID:29511483
A multi-omic analysis reveals the regulatory role of CD180 during the response of macrophages to Borrelia burgdorferi. PMID:29511161
Targeted sequencing reveals complex, phenotype-correlated genotypes in cystic fibrosis. PMID:29504914
Loss of microRNA-128 promotes cardiomyocyte proliferation and heart regeneration. PMID:29453456
Time- and polarity-dependent proteomic changes associated with homeostatic scaling at central synapses. PMID:29447110
The vesicle trafficking regulator PN_SCD1 is demethylated and overexpressed in florets of apomictic Paspalum notatum genotypes. PMID:29445151
Interleukin-6 and Interferon-α Signaling via JAK1-STAT Differentially Regulate Oncolytic versus Cytoprotective Antiviral States. PMID:29441069
Pi-Pi contacts are an overlooked protein feature relevant to phase separation. PMID:29424691
Decellularization and Solubilization of Porcine Liver for Use as a Substrate for Porcine Hepatocyte Culture: Method Optimization and Comparison. PMID:29390876
Patterns of variation in cis-regulatory regions: examining evidence of purifying selection. PMID:29373957
Proteomic Analysis of Nucleus Pulposus Cell-derived Extracellular Matrix Niche and Its Effect on Phenotypic Alteration of Dermal Fibroblasts. PMID:29367647
TimeLapse-seq: adding a temporal dimension to RNA sequencing through nucleoside recoding. PMID:29355846
QuantumClone: clonal assessment of functional mutations in cancer based on a genotype-aware method for clonal reconstruction. PMID:29342233
Cardiac protein expression patterns are associated with distinct inborn exercise capacity in non-selectively bred rats. PMID:29340527
Characteristics of MUTYH variants in Japanese colorectal polyposis patients. PMID:29330641
In silico VHL Gene Mutation Analysis and Prognosis of Pancreatic Neuroendocrine Tumors in von Hippel-Lindau Disease. PMID:29294023
Experimental Determination and Prediction of the Fitness Effects of Random Point Mutations in the Biosynthetic Enzyme HisA. PMID:29294020
A meta-analysis of associations of LEPR Q223R and K109R polymorphisms with Type 2 diabetes risk. PMID:29293570
Genetic variation in N- and C-terminal regions of bovine DNAJA1 heat shock protein gene in African, Asian and American cattle. PMID:29290829
Protein-Protein Interaction Network Analysis for a Biomarker Panel Related to Human Esophageal Adenocarcinoma. PMID:29286604
Quantitative proteomic analysis of murine white adipose tissue for peritoneal cancer metastasis. PMID:29282499
Proteomic analyses identify ARH3 as a serine mono-ADP-ribosylhydrolase. PMID:29234005
Loci and pathways associated with uterine capacity for pregnancy and fertility in beef cattle. PMID:29228019
DDX5/p68 associated lncRNA LOC284454 is differentially expressed in human cancers and modulates gene expression. PMID:29227193
PRC2 Is Dispensable in Vivo for β-Catenin-Mediated Repression of Chondrogenesis in the Mouse Embryonic Cranial Mesenchyme. PMID:29223978
Modulation of Immune Signaling and Metabolism Highlights Host and Fungal Transcriptional Responses in Mouse Models of Invasive Pulmonary Aspergillosis. PMID:29213115
Temporal analysis of hippocampal CA3 gene coexpression networks in a rat model of febrile seizures. PMID:29196444
Constitutively Active SMAD2/3 Are Broad-Scope Potentiators of Transcription-Factor-Mediated Cellular Reprogramming. PMID:29174331
Transcriptome sequencing of the long-nosed bandicoot (Perameles nasuta) reveals conservation and innovation of immune genes in the marsupial order Peramelemorphia. PMID:29159447
Investigation of common, low-frequency and rare genome-wide variation in anorexia nervosa. PMID:29155802
Identification of Pleiotropic Cancer Susceptibility Variants from Genome-Wide Association Studies Reveals Functional Characteristics. PMID:29150481
Systematic and site-specific analysis of N-sialoglycosylated proteins on the cell surface by integrating click chemistry and MS-based proteomics. PMID:29142707
Crosstalk between Receptor and Non-receptor Mediated Chemical Modes of Action in Rat Livers Converges through a Dysregulated Gene Expression Network at Tumor Suppressor Tp53. PMID:29114260
Mammalian γ2 AMPK regulates intrinsic heart rate. PMID:29097735
Isogenic Cellular Systems Model the Impact of Genetic Risk Variants in the Pathogenesis of Type 1 Diabetes. PMID:29093700
Survival and divergence in a small group: The extraordinary genomic history of the endangered Apennine brown bear stragglers. PMID:29078308
Molecular basis of CENP-C association with the CENP-A nucleosome at yeast centromeres. PMID:29074736
Computational Analysis of High Risk Missense Variant in Human UTY Gene: A Candidate Gene of AZFa Sub-region. PMID:29062794
Association analysis identifies 65 new breast cancer risk loci. PMID:29059683
Xenbase: a genomic, epigenomic and transcriptomic model organism database. PMID:29059324
Lipid metabolic perturbation is an early-onset phenotype in adult spinster mutants: a Drosophila model for lysosomal storage disorders. PMID:29046397
Transcription factor 19 interacts with histone 3 lysine 4 trimethylation and controls gluconeogenesis via the nucleosome-remodeling-deacetylase complex. PMID:29042441
Data on chow, liver tissue and mitochondrial fatty acid compositions as well as mitochondrial proteome changes after feeding mice a western diet for 6-24 weeks. PMID:29034285
Genome-Wide Identification of Transcription Factor-Binding Sites in Quiescent Adult Neural Stem Cells. PMID:29030827
Resources for Interpreting Variants in Precision Genomic Oncology Applications. PMID:28975082
Low-dose rapamycin extends lifespan in a mouse model of mtDNA depletion syndrome. PMID:28973153
Quantitative multiplexed proteomics of Taenia solium cysts obtained from the skeletal muscle and central nervous system of pigs. PMID:28945737
Thiol-linked alkylation of RNA to assess expression dynamics. PMID:28945705
Spatial distribution of disease-associated variants in three-dimensional structures of protein complexes. PMID:28945216
Porcine Esophageal Submucosal Gland Culture Model Shows Capacity for Proliferation and Differentiation. PMID:28936470
Exploration of the bovine colostrum proteome and effects of heat treatment time on colostrum protein profile. PMID:28918156
Divergence in Morris Water Maze-Based Cognitive Performance under Chronic Stress Is Associated with the Hippocampal Whole Transcriptomic Modification in Mice. PMID:28912681
miR-217-5p induces apoptosis by directly targeting PRKCI, BAG3, ITGAV and MAPK1 in colorectal cancer cells. PMID:28905214
SERPING1 mRNA overexpression in monocytes from HIV+ patients. PMID:28889214
Identifying relationships between unrelated pharmaceutical target proteins on the basis of shared active compounds. PMID:28884009
Molecular modeling and structure-based drug discovery approach reveals protein kinases as off-targets for novel anticancer drug RH1. PMID:28879492
The immunosuppressive effect of the tick protein, Salp15, is long-lasting and persists in a murine model of hematopoietic transplant. PMID:28878331
Comparative quantitative proteomic analysis of disease stratified laser captured microdissected human islets identifies proteins and pathways potentially related to type 1 diabetes. PMID:28877242
BUFET: boosting the unbiased miRNA functional enrichment analysis using bitsets. PMID:28874117
Single-Base Resolution Mapping of 5-Hydroxymethylcytosine Modifications in Hippocampus of Alzheimer's Disease Subjects. PMID:28866733
Discerning the Origins of the Negritos, First Sundaland People: Deep Divergence and Archaic Admixture. PMID:28854687
Nevirapine induced mitochondrial dysfunction in HepG2 cells. PMID:28835669
Proteomic Analysis of Elevated Intraocular Pressure with Retinal Detachment. PMID:28825049
Genome-wide identification and expression analysis of E2 ubiquitin-conjugating enzymes in tomato. PMID:28819320
Systematic Selection of Reference Genes for the Normalization of Circulating RNA Transcripts in Pregnant Women Based on RNA-Seq Data. PMID:28777335
Dynamic hyper-editing underlies temperature adaptation in Drosophila. PMID:28746393
Genetic Architecture of Flooding Tolerance in the Dry Bean Middle-American Diversity Panel. PMID:28729876
Elucidation of the molecular mechanisms underlying adverse reactions associated with a kinase inhibitor using systems toxicology. PMID:28725458
Major Novel QTL for Resistance to Cassava Bacterial Blight Identified through a Multi-Environmental Analysis. PMID:28725234
Comparative proteome analysis for identification of differentially abundant proteins in SIDS. PMID:28717962
Microarray analysis reveals key genes and pathways in Tetralogy of Fallot. PMID:28713939
Temporal dynamics of neurogenomic plasticity in response to social interactions in male threespined sticklebacks. PMID:28704398
Transcriptomic Response of Purple Willow (Salix purpurea) to Arsenic Stress. PMID:28702037
Activating transcription factor 3 promotes loss of the acinar cell phenotype in response to cerulein-induced pancreatitis in mice. PMID:28701342
A case-control study on association of proteasome subunit beta 8 (PSMB8) and transporter associated with antigen processing 1 (TAP1) polymorphisms and their transcript levels in vitiligo from Gujarat. PMID:28700671
Large-Scale Analysis of Breast Cancer-Related Conformational Changes in Proteins Using SILAC-SPROX. PMID:28673085
RGIFE: a ranked guided iterative feature elimination heuristic for the identification of biomarkers. PMID:28666416
SUMOylation pathway alteration coupled with downregulation of SUMO E2 enzyme at mucosal epithelium modulates inflammation in inflammatory bowel disease. PMID:28659381
WetA bridges cellular and chemical development in Aspergillus flavus. PMID:28658268
Identification of introns harboring functional sequence elements through positional conservation. PMID:28646210
A sorghum (Sorghum bicolor) mutant with altered carbon isotope ratio. PMID:28640841
Delineating the genetic heterogeneity of OCA in Hungarian patients. PMID:28629449
Improving the detection of pathways in genome-wide association studies by combined effects of SNPs from Linkage Disequilibrium blocks. PMID:28615668
Time-Dependent, HIV-Tat-Induced Perturbation of Human Neurons In Vitro: Towards a Model for the Molecular Pathology of HIV-Associated Neurocognitive Disorders. PMID:28611588
PHF6 regulates phenotypic plasticity through chromatin organization within lineage-specific genes. PMID:28607179
Life or death: disease-tolerant coral species activate autophagy following immune challenge. PMID:28592676
KCNJ11, ABCC8 and TCF7L2 polymorphisms and the response to sulfonylurea treatment in patients with type 2 diabetes: a bioinformatics assessment. PMID:28587604
Evidence of Altered Mitochondrial Protein Expression After Chronic Ethanol Consumption in the Aged Estrogen-Deficient Female Rat Heart. PMID:28543099
Pharmacological Stimulation of Phagocytosis Enhances Amyloid Plaque Clearance; Evidence from a Transgenic Mouse Model of ATTR Neuropathy. PMID:28539873
Early social learning triggers neurogenomic expression changes in a swordtail fish. PMID:28515207
Across-proteome modeling of dimer structures for the bottom-up assembly of protein-protein interaction networks. PMID:28499419
Single-trait and multi-trait genome-wide association analyses identify novel loci for blood pressure in African-ancestry populations. PMID:28498854
microRNA-200a-3p increases 5-fluorouracil resistance by regulating dual specificity phosphatase 6 expression. PMID:28496200
Human DDX21 binds and unwinds RNA guanine quadruplexes. PMID:28472472
Chromosomal Alterations and Gene Expression Changes Associated with the Progression of Leukoplakia to Advanced Gingivobuccal Cancer. PMID:28433800
Evolutionary adaptation revealed by comparative genome analysis of woolly mammoths and elephants. PMID:28369217
Comparative analysis of MBD-seq and MeDIP-seq and estimation of gene expression changes in a rodent model of schizophrenia. PMID:28365388
Genome-wide methylation analysis identifies a core set of hypermethylated genes in CIMP-H colorectal cancer. PMID:28351398
Structure-based functional annotation of hypothetical proteins from Candida dubliniensis: a quest for potential drug targets. PMID:28324558
Extensive Copy Number Variation in Fermentation-Related Genes Among Saccharomyces cerevisiae Wine Strains. PMID:28292787
Neuropeptide VGF Promotes Maturation of Hippocampal Dendrites That Is Reduced by Single Nucleotide Polymorphisms. PMID:28287464
Genomic variants reveal differential evolutionary constraints on human transglutaminases and point towards unrecognized significance of transglutaminase 2. PMID:28248968
Preparing and Analyzing Expressed Sequence Tags (ESTs) Library for the Mammary Tissue of Local Turkish Kivircik Sheep. PMID:28239610
Fatty acid synthase inhibits the O-GlcNAcase during oxidative stress. PMID:28232487
Predicting phenotype from genotype: Improving accuracy through more robust experimental and computational modeling. PMID:28230923
Gene Expression Profiling in the Injured Spinal Cord of Trachemys scripta elegans: An Amniote with Self-Repair Capabilities. PMID:28223917
La Deletion from Mouse Brain Alters Pre-tRNA Metabolism and Accumulation of Pre-5.8S rRNA, with Neuron Death and Reactive Astrocytosis. PMID:28223366
The genome landscape of indigenous African cattle. PMID:28219390
Differential Binding of Three Major Human ADAR Isoforms to Coding and Long Non-Coding Transcripts. PMID:28208661
Transcriptome Profiling of In-Vivo Produced Bovine Pre-implantation Embryos Using Two-color Microarray Platform. PMID:28190024
A network-based pathway-expanding approach for pathway analysis. PMID:28155638
Transcriptomic Modification in the Cerebral Cortex following Noninvasive Brain Stimulation: RNA-Sequencing Approach. PMID:28119786
Identification of microRNAs implicated in the late differentiation stages of normal B cells suggests a central role for miRNA targets ZEB1 and TP53. PMID:28107180
Identification of shared and unique gene families associated with oral clefts. PMID:28106045
ProClaT, a new bioinformatics tool for in silico protein reclassification: case study of DraB, a protein coded from the draTGB operon in Azospirillum brasilense. PMID:28105917
Urinary Extracellular Vesicles: Potential Biomarkers of Renal Function in Diabetic Patients. PMID:28105442
Methyl-CpG-Binding Protein MBD1 Regulates Neuronal Lineage Commitment through Maintaining Adult Neural Stem Cell Identity. PMID:28100736
Genome-wide standing variation facilitates long-term response to bidirectional selection for antibody response in chickens. PMID:28100171
Differential Effects of Vitamins A and D on the Transcriptional Landscape of Human Monocytes during Infection. PMID:28094291
Transcriptomic evidence for the control of soybean root isoflavonoid content by regulation of overlapping phenylpropanoid pathways. PMID:28077078
pHMM-tree: phylogeny of profile hidden Markov models. PMID:28062446
A Genome-wide Association Study Identifies Risk Alleles in Plasminogen and P4HA2 Associated with Giant Cell Arteritis. PMID:28041642
Gene-based analyses reveal novel genetic overlap and allelic heterogeneity across five major psychiatric disorders. PMID:28035465
VaProS: a database-integration approach for protein/genome information retrieval. PMID:28012137
Weighted Protein Interaction Network Analysis of Frontotemporal Dementia. PMID:28004582
Evidence of Recent Intricate Adaptation in Human Populations. PMID:27992444
Senescence marker protein 30 (SMP30) serves as a potential prognostic indicator in hepatocellular carcinoma. PMID:27991558
Combination Epigenetic Therapy in Advanced Breast Cancer with 5-Azacitidine and Entinostat: A Phase II National Cancer Institute/Stand Up to Cancer Study. PMID:27979916
In Silico identification of SNP diversity in cultivated and wild tomato species: insight from molecular simulations. PMID:27929054
Dataset of eye disease-related proteins analyzed using the unfolding mutation screen. PMID:27922631
Association of SNP variants of MHC Class II DRB gene with thermo-physiological traits in tropical goats. PMID:27909914
In silico Mapping of Protein Unfolding Mutations for Inherited Disease. PMID:27905547
PANTHER version 11: expanded annotation data from Gene Ontology and Reactome pathways, and data analysis tool enhancements. PMID:27899595
Single Amino Acid Repeats in the Proteome World: Structural, Functional, and Evolutionary Insights. PMID:27893794
Towards Functional Annotation of the Preimplantation Transcriptome: An RNAi Screen in Mammalian Embryos. PMID:27869233
Normal chromosome conformation depends on subtelomeric facultative heterochromatin in Neurospora crassa. PMID:27856763
Multiparameter functional diversity of human C2H2 zinc finger proteins. PMID:27852650
Regulatory landscape and clinical implication of MBD3 in human malignant glioma. PMID:27835581
Characterization of exosomal release in bovine endometrial intercaruncular stromal cells. PMID:27829441
REST regulation of gene networks in adult neural stem cells. PMID:27819263
Large-Scale Analysis of Breast Cancer-Related Conformational Changes in Proteins Using Limited Proteolysis. PMID:27794609
Microenvironmental Gene Expression Plasticity Among Individual Drosophila melanogaster. PMID:27770026
Comparative functional characterization of novel non-syndromic GJB2 gene variant p.Gly45Arg and lethal syndromic variant p.Gly45Glu. PMID:27761313
Label-free LC-MS/MS shotgun proteomics to investigate the anti-inflammatory effect of rCC16. PMID:27748820
Foxp3 and Toll-like receptor signaling balance Treg cell anabolic metabolism for suppression. PMID:27695003
Analysis of microRNA and Gene Expression Profiles in Multiple Sclerosis: Integrating Interaction Data to Uncover Regulatory Mechanisms. PMID:27694855
Systematic Search for Evidence of Interdomain Horizontal Gene Transfer from Prokaryotes to Oomycete Lineages. PMID:27642638
Comparative protein profiling of B16 mouse melanoma cells susceptible and non-susceptible to alphavirus infection: Effect of the tumor microenvironment. PMID:27636533
PGD: a pangolin genome hub for the research community. PMID:27616775
Functional networks inference from rule-based machine learning models. PMID:27597880
Dynamic DNA methylation regulates neuronal intrinsic membrane excitability. PMID:27555660
Several type 2 diabetes-associated variants in genes annotated to WNT signaling interact with dietary fiber in relation to incidence of type 2 diabetes. PMID:27551309
Born blonde: a recessive loss-of-function mutation in the melanocortin 1 receptor is associated with cream coat coloration in Antarctic fur seals. PMID:27547348
Inferring Crohn's disease association from exome sequences by integrating biological knowledge. PMID:27535358
Comparative proteomic profiling of refractory/relapsed multiple myeloma reveals biomarkers involved in resistance to bortezomib-based therapy. PMID:27527861
Supplements of vitamins B9 and B12 affect hepatic and mammary gland gene expression profiles in lactating dairy cows. PMID:27526683
B Cell Receptor Activation Predominantly Regulates AKT-mTORC1/2 Substrates Functionally Related to RNA Processing. PMID:27487157
Mitochondria Biogenesis and Bioenergetics Gene Profiles in Isogenic Prostate Cells with Different Malignant Phenotypes. PMID:27478826
Genome-Wide Divergence in the West-African Malaria Vector Anopheles melas. PMID:27466271
A De Novo-Assembly Based Data Analysis Pipeline for Plant Obligate Parasite Metatranscriptomic Studies. PMID:27462318
MicroRNA expression and gene regulation drive breast cancer progression and metastasis in PyMT mice. PMID:27449149
Circulating cell-free mature microRNAs and their target gene prediction in bovine metritis. PMID:27404038
Molecular Profile of Tumor-Specific CD8+ T Cell Hypofunction in a Transplantable Murine Cancer Model. PMID:27371726
In silico analysis of deleterious single nucleotide polymorphisms in human BUB1 mitotic checkpoint serine/threonine kinase B gene. PMID:27331020
Target and resistance-related proteins of recombinant mutant human tumor necrosis factor-related apoptosis-inducing ligand on myeloma cell lines. PMID:27284413
Identification of RNA-binding Proteins in Macrophages by Interactome Capture. PMID:27281784
Tools for Predicting the Functional Impact of Nonsynonymous Genetic Variation. PMID:27270698
Characterization and use of HapT1-derived homologous tumors as a preclinical model to evaluate therapeutic efficacy of drugs against pancreatic tumor desmoplasia. PMID:27259232
A dataset for assessing temporal changes in gene expression during the aging process of adult Drosophila melanogaster. PMID:27252981
Transcriptome Analysis Reveals a Signature Profile for Tick-Borne Flavivirus Persistence in HEK 293T Cells. PMID:27222466
A de novo transcriptome analysis shows that modulation of the JAK-STAT signaling pathway by salmonid alphavirus subtype 3 favors virus replication in macrophage/dendritic-like TO-cells. PMID:27215196
Divergence of a conserved elongation factor and transcription regulation in budding and fission yeast. PMID:27197211
Whole-transcriptome analysis of UUO mouse model of renal fibrosis reveals new molecular players in kidney diseases. PMID:27189340
Towards Increasing the Clinical Relevance of In Silico Methods to Predict Pathogenic Missense Variants. PMID:27171182
StructMAn: annotation of single-nucleotide polymorphisms in the structural context. PMID:27150811
KeyPathwayMinerWeb: online multi-omics network enrichment. PMID:27150809
Comparison of pathogenicity prediction tools on missense variants in RYR1 and CACNA1S associated with malignant hyperthermia. PMID:27147545
Label-Free Quantitative Proteomics Reveals Differences in Molecular Mechanism of Atherosclerosis Related and Non-Related to Chronic Kidney Disease. PMID:27144566
Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) Protein-Protein Interaction Inhibitor Reveals a Non-catalytic Role for GAPDH Oligomerization in Cell Death. PMID:27129213
GCGene: a gene resource for gastric cancer with literature evidence. PMID:27127885
Mechanical cell competition kills cells via induction of lethal p53 levels. PMID:27109213
Analysis of microRNA expression during the torpor-arousal cycle of a mammalian hibernator, the 13-lined ground squirrel. PMID:27084747
GPR56 contributes to the development of acute myeloid leukemia in mice. PMID:27063597
Scaffold proteins LACK and TRACK as potential drug targets in kinetoplastid parasites: Development of inhibitors. PMID:27054066
Identification of Deleterious Mutations in Myostatin Gene of Rohu Carp (Labeo rohita) Using Modeling and Molecular Dynamic Simulation Approaches. PMID:27019850
Phylotranscriptomic analysis uncovers a wealth of tissue inhibitor of metalloproteinases variants in echinoderms. PMID:27017967
Integrative Single-Cell Transcriptomics Reveals Molecular Networks Defining Neuronal Maturation During Postnatal Neurogenesis. PMID:26989163
ENTPRISE: An Algorithm for Predicting Human Disease-Associated Amino Acid Substitutions from Sequence Entropy and Predicted Protein Structures. PMID:26982818
Novel point mutations in the ERG11 gene in clinical isolates of azole resistant Candida species. PMID:26982177
REGene: a literature-based knowledgebase of animal regeneration that bridge tissue regeneration and cancer. PMID:26975833
Mitonuclear Epistasis for Development Time and Its Modification by Diet in Drosophila. PMID:26966258
The Role of CD44 and ERM Proteins in Expression and Functionality of P-glycoprotein in Breast Cancer Cells. PMID:26938523
Type 1 diabetes cadaveric human pancreata exhibit a unique exocrine tissue proteomic profile. PMID:26935967
Uncovering the pathways underlying whole body regeneration in a chordate model, Botrylloides leachi using de novo transcriptome analysis. PMID:26879048
The next generation of metastatic melanoma: uncovering the genetic variants for anti-BRAF therapy response. PMID:26863566
HIV-1 transgenic rats display mitochondrial abnormalities consistent with abnormal energy generation and distribution. PMID:26843384
Reconstruction of the insulin-like signalling pathway of Haemonchus contortus. PMID:26842675
A review of the new HGNC gene family resource. PMID:26842383
Impact of germline and somatic missense variations on drug binding sites. PMID:26810135
Fast and Rigorous Computation of Gene and Pathway Scores from SNP-Based Summary Statistics. PMID:26808494
Differential gene expression in dentate granule cells in mesial temporal lobe epilepsy with and without hippocampal sclerosis. PMID:26799155
Insight into the Salivary Gland Transcriptome of Lygus lineolaris (Palisot de Beauvois). PMID:26789269
Genetic Variability Overrides the Impact of Parental Cell Type and Determines iPSC Differentiation Potential. PMID:26777058
CSGene: a literature-based database for cell senescence genes and its application to identify critical cell aging pathways and associated diseases. PMID:26775705
KDM4C and ATF4 Cooperate in Transcriptional Control of Amino Acid Metabolism. PMID:26774480
Identification of genomic variants putatively targeted by selection during dog domestication. PMID:26754411
Changes in Expression of Genes Regulating Airway Inflammation Following a High-Fat Mixed Meal in Asthmatics. PMID:26751474
ECGene: A Literature-Based Knowledgebase of Endometrial Cancer Genes. PMID:26699919
Accumulation of differentiating intestinal stem cell progenies drives tumorigenesis. PMID:26690827
Identification of methylated deoxyadenosines in vertebrates reveals diversity in DNA modifications. PMID:26689968
Genome-wide analysis reveals NRP1 as a direct HIF1α-E2F7 target in the regulation of motorneuron guidance in vivo. PMID:26681691
Integrating Diverse Types of Genomic Data to Identify Genes that Underlie Adverse Pregnancy Phenotypes. PMID:26641094
Elucidating the Molecular Composition of Cartilage by Proteomics. PMID:26632656
Mitochondrial Involvement in Vertebrate Speciation? The Case of Mito-nuclear Genetic Divergence in Chameleons. PMID:26590214
Draft Genome Sequence of the Fungus Trametes hirsuta 072. PMID:26586872
Protein Destabilization as a Common Factor in Diverse Inherited Disorders. PMID:26584803
Transcriptator: An Automated Computational Pipeline to Annotate Assembled Reads and Identify Non Coding RNA. PMID:26581084
PANTHER version 10: expanded protein families and functions, and analysis tools. PMID:26578592
Investigation of the fatty acid transporter-encoding genes SLC27A3 and SLC27A4 in autism. PMID:26548558
Exploring multiple quantitative trait loci models of hepatic fibrosis in a mouse intercross. PMID:26547557
A Novel SLC27A4 Splice Acceptor Site Mutation in Great Danes with Ichthyosis. PMID:26506231
An evidence-based knowledgebase of metastasis suppressors to identify key pathways relevant to cancer metastasis. PMID:26486520
Systems Biology for Smart Crops and Agricultural Innovation: Filling the Gaps between Genotype and Phenotype for Complex Traits Linked with Robust Agricultural Productivity and Sustainability. PMID:26484978
In silico analysis of consequences of non-synonymous SNPs of Slc11a2 gene in Indian bovines. PMID:26484229
MicroRNA-148a regulates LDL receptor and ABCA1 expression to control circulating lipoprotein levels. PMID:26437365
Apoptosis transcriptional mechanism of feline infectious peritonitis virus infected cells. PMID:26386572
Stimulation of Innate and Adaptive Immunity by Using Filamentous Bacteriophage fd Targeted to DEC-205. PMID:26380324
AntiAngioPred: A Server for Prediction of Anti-Angiogenic Peptides. PMID:26335203
A Genome-wide Scan for Selective Sweeps in Racing Horses. PMID:26333666
Proteomic Analysis of Disease Stratified Human Pancreas Tissue Indicates Unique Signature of Type 1 Diabetes. PMID:26302420
Identification of IDUA and WNT16 Phosphorylation-Related Non-Synonymous Polymorphisms for Bone Mineral Density in Meta-Analyses of Genome-Wide Association Studies. PMID:26256109
A draft network of ligand-receptor-mediated multicellular signalling in human. PMID:26198319
Inferring pathway dysregulation in cancers from multiple types of omic data. PMID:26170901
Genome-Wide Profiling of Histone Modifications (H3K9me2 and H4K12ac) and Gene Expression in Rust (Uromyces appendiculatus) Inoculated Common Bean (Phaseolus vulgaris L.). PMID:26167691
The miR-199-dynamin regulatory axis controls receptor-mediated endocytosis. PMID:26163491
Cancer as the Disintegration of Robustness: Population-Level Variance in Gene Expression Identifies Key Differences Between Tobacco- and HPV-Associated Oropharyngeal Carcinogenesis. PMID:26132601
Systems analysis of gene ontology and biological pathways involved in post-myocardial infarction responses. PMID:26100218
dbEMT: an epithelial-mesenchymal transition associated gene resource. PMID:26099468
Genome-Wide Gene Expression in relation to Age in Large Laboratory Cohorts of Drosophila melanogaster. PMID:26090231
CD24 tracks divergent pluripotent states in mouse and human cells. PMID:26076835
Pedican: an online gene resource for pediatric cancers with literature evidence. PMID:26073932
Predicting the Pathogenic Potential of BRCA1 and BRCA2 Gene Variants Identified in Clinical Genetic Testing. PMID:26052455
Analysis of gene expression during aging of CGNs in culture: implication of SLIT2 and NPY in senescence. PMID:26047956
Large-Scale Evolutionary Analysis of Genes and Supergene Clusters from Terpenoid Modular Pathways Provides Insights into Metabolic Diversification in Flowering Plants. PMID:26046541
The road from next-generation sequencing to personalized medicine. PMID:26000024
Draft Genome Sequence of Sporidiobolus salmonicolor CBS 6832, a Red-Pigmented Basidiomycetous Yeast. PMID:25999568
Differential Genes Expression between Fertile and Infertile Spermatozoa Revealed by Transcriptome Analysis. PMID:25973848
Comparative transcriptome profiling approach to glean virulence and immunomodulation-related genes of Fasciola hepatica. PMID:25956885
Identifying genes that mediate anthracyline toxicity in immune cells. PMID:25926793
Identification of Reproduction-Related Gene Polymorphisms Using Whole Transcriptome Sequencing in the Large White Pig Population. PMID:25917919
A mass spectrometric-derived cell surface protein atlas. PMID:25894527
Cardiac protein changes in rats after soybean oil treatment: a proteomic study. PMID:25889944
The proteome of postsurgical pancreatic juice. PMID:25875796
The nuclear receptors of Biomphalaria glabrata and Lottia gigantea: implications for developing new model organisms. PMID:25849443
Proteomic analysis of human follicular fluid from fertile women. PMID:25838815
Variability in pathogenicity prediction programs: impact on clinical diagnostics. PMID:25802880
Prediction of the damage-associated non-synonymous single nucleotide polymorphisms in the human MC1R gene. PMID:25794181
Phenotype specific analyses reveal distinct regulatory mechanism for chronically activated p53. PMID:25790137
Canine urothelial carcinoma: genomically aberrant and comparatively relevant. PMID:25783786
MicroRNAs are part of the regulatory network that controls EGF induced apoptosis, including elements of the JAK/STAT pathway, in A431 cells. PMID:25781916
LC-MS/MS-based serum proteomics for identification of candidate biomarkers for hepatocellular carcinoma. PMID:25778709
In silico screening, genotyping, molecular dynamics simulation and activity studies of SNPs in pyruvate kinase M2. PMID:25768091
Computational methodology for ChIP-seq analysis. PMID:25741452
The diagnostic role of cervico-vaginal fluid interleukins-1α in endometriosis: A case-control study. PMID:25709655
The alpaca melanocortin 1 receptor: gene mutations, transcripts, and relative levels of expression in ventral skin biopsies. PMID:25685836
The Arabidopsis alkaline ceramidase TOD1 is a key turgor pressure regulator in plant cells. PMID:25591940
Comparison and integration of deleteriousness prediction methods for nonsynonymous SNVs in whole exome sequencing studies. PMID:25552646
A 3-biomarker-panel predicts renal outcome in patients with proteinuric renal diseases. PMID:25540021
Essential role for TMEM100 in vascular integrity but limited contributions to the pathogenesis of hereditary haemorrhagic telangiectasia. PMID:25538155
Conserved proline-directed phosphorylation regulates SR protein conformation and splicing function. PMID:25529026
Accounting for eXentricities: analysis of the X chromosome in GWAS reveals X-linked genes implicated in autoimmune diseases. PMID:25479423
Pathway-based analysis tools for complex diseases: a review. PMID:25462153
Comparative genomics of closely related Salmonella enterica serovar Typhi strains reveals genome dynamics and the acquisition of novel pathogenic elements. PMID:25412680
Exome sequencing identifies novel and recurrent mutations in GJA8 and CRYGD associated with inherited cataract. PMID:25403472
Identification of regulatory factors for mesenchymal stem cell-derived salivary epithelial cells in a co-culture system. PMID:25402494
Genome-wide microarray expression and genomic alterations by array-CGH analysis in neuroblastoma stem-like cells. PMID:25392930
Genome-wide analyses and functional classification of proline repeat-rich proteins: potential role of eIF5A in eukaryotic evolution. PMID:25364902
From molecular signatures to predictive biomarkers: modeling disease pathophysiology and drug mechanism of action. PMID:25364744
Identification of novel tumor-associated cell surface sialoglycoproteins in human glioblastoma tumors using quantitative proteomics. PMID:25360666
The Long-HER study: clinical and molecular analysis of patients with HER2+ advanced breast cancer who become long-term survivors with trastuzumab-based therapy. PMID:25330188
Gene polymorphisms in pattern recognition receptors and susceptibility to idiopathic recurrent vulvovaginal candidiasis. PMID:25295030
Quantitative proteomics analysis identifies mitochondria as therapeutic targets of multidrug-resistance in ovarian cancer. PMID:25285166
Fluvastatin mediated breast cancer cell death: a proteomic approach to identify differentially regulated proteins in MDA-MB-231 cells. PMID:25268751
Quantitative phosphoproteomics reveals crosstalk between phosphorylation and O-GlcNAc in the DNA damage response pathway. PMID:25263469
Single nucleotide variations: biological impact and theoretical interpretation. PMID:25234433
Human germline and pan-cancer variomes and their distinct functional profiles. PMID:25232094
Identification of gene expression profile in the rat brain resulting from acute alcohol intoxication. PMID:25218841
A novel mutation in TFL1 homolog affecting determinacy in cowpea (Vigna unguiculata). PMID:25146839
Novel mitochondrial mutations in the ATP6 and ATP8 genes in patients with breast cancer. PMID:25110199
De novo missense mutations in the NAA10 gene cause severe non-syndromic developmental delay in males and females. PMID:25099252
High quality RNA in semen and sperm: isolation, analysis and potential application in clinical testing. PMID:25088949
Single Nucleotide Polymorphisms of NLRP12 Gene and Association with Non-specific Digestive Disorder in Rabbit. PMID:25049887
Nicotine and oxidative stress induced exomic variations are concordant and overrepresented in cancer-associated genes. PMID:24947164
Gene co-expression network analysis identifies porcine genes associated with variation in Salmonella shedding. PMID:24912583
In silico identification of genetic variants in glucocerebrosidase (GBA) gene involved in Gaucher's disease using multiple software tools. PMID:24904648
A bioinformatic and computational study of myosin phosphatase subunit diversity. PMID:24898838
Cooperativity and equilibrium with FOXA1 define the androgen receptor transcriptional program. PMID:24875621
An In silico Based Comparison of Drug Interactions in Wild and Mutant Human β-tubulin through Docking Studies. PMID:24834310
The histone lysine demethylase JMJD3/KDM6B is recruited to p53 bound promoters and enhancer elements in a p53 dependent manner. PMID:24797517
Mammalian Y chromosomes retain widely expressed dosage-sensitive regulators. PMID:24759411
Translation control of TAK1 mRNA by hnRNP K modulates LPS-induced macrophage activation. PMID:24751651
The KIT gene is associated with the english spotting coat color locus and congenital megacolon in Checkered Giant rabbits (Oryctolagus cuniculus). PMID:24736498
No large-effect low-frequency coding variation found for myocardial infarction. PMID:24728188
Oncostatin M mediates STAT3-dependent intestinal epithelial restitution via increased cell proliferation, decreased apoptosis and upregulation of SERPIN family members. PMID:24710357
Large-scale RNA interference screening in mammalian cells identifies novel regulators of mutant huntingtin aggregation. PMID:24705917
Transcriptomic analysis of the highly derived radial body plan of a sea urchin. PMID:24696402
Recent advances in functional region prediction by using structural and evolutionary information - Remaining problems and future extensions. PMID:24688747
PATHOME: an algorithm for accurately detecting differentially expressed subpathways. PMID:24681952
Endogenously imprinted genes in Drosophila melanogaster. PMID:24658702
Searching for novel Cdk5 substrates in brain by comparative phosphoproteomics of wild type and Cdk5-/- mice. PMID:24658276
General assessment of copy number variation in normal and tumor tissues of the domestic dog (Canis lupus familiaris). PMID:24573641
Brain microRNAs and insights into biological functions and therapeutic potential of brain enriched miRNA-128. PMID:24555688
Wig-1 regulates cell cycle arrest and cell death through the p53 targets FAS and 14-3-3σ. PMID:24469038
PredictSNP: robust and accurate consensus classifier for prediction of disease-related mutations. PMID:24453961
Novel pathophysiological markers are revealed by iTRAQ-based quantitative clinical proteomics approach in vascular dementia. PMID:24448401
A genetic model of differential susceptibility to human respiratory syncytial virus (RSV) infection. PMID:24421397
The demethylase JMJD2C localizes to H3K4me3-positive transcription start sites and is dispensable for embryonic development. PMID:24396064
Secretome analysis of human oligodendrocytes derived from neural stem cells. PMID:24392122
Quantitative phosphoproteomic analysis identifies activation of the RET and IGF-1R/IR signaling pathways in neuroblastoma. PMID:24349301
Next generation sequencing analysis of human platelet PolyA+ mRNAs and rRNA-depleted total RNA. PMID:24349131
Feature-based classification of amino acid substitutions outside conserved functional protein domains. PMID:24348198
Status quo of annotation of human disease variants. PMID:24305467
In-silico screening of cancer associated mutation on PLK1 protein and its structural consequences. PMID:24271645
Heterogeneous tempo and mode of conserved noncoding sequence evolution among four mammalian orders. PMID:24259317
Pthlh, a promising cancer modifier gene in rat tongue carcinogenesis. PMID:24253735
The human placental sexome differs between trophoblast epithelium and villous vessel endothelium. PMID:24205377
Widespread decreased expression of immune function genes in human peripheral blood following radiation exposure. PMID:24168352
Effect of curcumin on aged Drosophila melanogaster: a pathway prediction analysis. PMID:24155070
Rare variants in calcium homeostasis modulator 1 (CALHM1) found in early onset Alzheimer's disease patients alter calcium homeostasis. PMID:24069280
Integrated genomic analysis of triple-negative breast cancers reveals novel microRNAs associated with clinical and molecular phenotypes and sheds light on the pathways they control. PMID:24059244
Agrigenomics for microalgal biofuel production: an overview of various bioinformatics resources and recent studies to link OMICS to bioenergy and bioeconomy. PMID:24044362
IQdb: an intelligence quotient score-associated gene resource for human intelligence. PMID:24030781
Epstein-Barr virus induces global changes in cellular mRNA isoform usage that are important for the maintenance of latency. PMID:24027308
A genome- and phenome-wide association study to identify genetic variants influencing platelet count and volume and their pleiotropic effects. PMID:24026423
Review of processing and analysis methods for DNA methylation array data. PMID:23982603
Towards precision medicine: advances in computational approaches for the analysis of human variants. PMID:23962656
Green fluorescent protein expression triggers proteome changes in breast cancer cells. PMID:23899627
Functional coding variants in SLC6A15, a possible risk gene for major depression. PMID:23874702
Molecular mechanisms of disease-causing missense mutations. PMID:23871686
Large-scale gene function analysis with the PANTHER classification system. PMID:23868073
In silico screening and molecular dynamics simulation of disease-associated nsSNP in TYRP1 gene and its structural consequences in OCA3. PMID:23862152
Dietary selenium deficiency exacerbates DSS-induced epithelial injury and AOM/DSS-induced tumorigenesis. PMID:23861820
Characterizing the Genetic Basis for Nicotine Induced Cancer Development: A Transcriptome Sequencing Study. PMID:23825647
Identifying Mendelian disease genes with the variant effect scoring tool. PMID:23819870
In silico prediction of a disease-associated STIL mutant and its affect on the recruitment of centromere protein J (CENPJ). PMID:23772360
Genome-wide profiling of human cap-independent translation-enhancing elements. PMID:23770754
Phylogenetic portrait of the Saccharomyces cerevisiae functional genome. PMID:23749449
708 Common and 2010 rare DISC1 locus variants identified in 1542 subjects: analysis for association with psychiatric disorder and cognitive traits. PMID:23732877
The genome of the anaerobic fungus Orpinomyces sp. strain C1A reveals the unique evolutionary history of a remarkable plant biomass degrader. PMID:23709508
Proteomic signatures of acquired letrozole resistance in breast cancer: suppressed estrogen signaling and increased cell motility and invasiveness. PMID:23704778
Identification of single nucleotide polymorphisms in the agouti signaling protein (ASIP) gene in some goat breeds in tropical and temperate climates. PMID:23661018
Chronic carvedilol treatment partially reverses the right ventricular failure transcriptional profile in experimental pulmonary hypertension. PMID:23632417
P.Arg82Leu von Hippel-Lindau (VHL) gene mutation among three members of a family with familial bilateral pheochromocytoma in India: molecular analysis and in silico characterization. PMID:23626751
Predicting the functional consequences of cancer-associated amino acid substitutions. PMID:23620363
Differential gene expression related to Nora virus infection of Drosophila melanogaster. PMID:23603562
Knowledge discovery in variant databases using inductive logic programming. PMID:23589683
Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders. PMID:23583979
Gene expression analysis distinguishes tissue-specific and gender-related functions among adult Ascaris suum tissues. PMID:23572074
Functional recurrent mutations in the human mitochondrial phylogeny: dual roles in evolution and disease. PMID:23563965
Developmental profiles of the murine palatal methylome. PMID:23554260
Novel frem1-related mouse phenotypes and evidence of genetic interactions with gata4 and slit3. PMID:23536828
Systematic investigation of predicted effect of nonsynonymous SNPs in human prion protein gene: a molecular modeling and molecular dynamics study. PMID:23527686
Induction of RET dependent and independent pro-inflammatory programs in human peripheral blood mononuclear cells from Hirschsprung patients. PMID:23527089
Mass spectrometry identification of granins and other proteins secreted by neuroblastoma cells. PMID:23519838
Differential expression analysis for pathways. PMID:23516350
Protein function prediction using domain families. PMID:23514456
Cross-species analysis of nicotine-induced proteomic alterations in pancreatic cells. PMID:23456891
Cancer cell response to anthracyclines effects: mysteries of the hidden proteins associated with these drugs. PMID:23443080
Exome sequencing identifies GNB4 mutations as a cause of dominant intermediate Charcot-Marie-Tooth disease. PMID:23434117
A Case Study of Monozygotic Twins Apparently Homozygous for a Novel Variant of UDP-Galactose 4'-epimerase (GALE) : A Complex Case of Variant GALE. PMID:23430501
Multilevel omic data integration in cancer cell lines: advanced annotation and emergent properties. PMID:23418673
Concise review: new paradigms for Down syndrome research using induced pluripotent stem cells: tackling complex human genetic disease. PMID:23413375
A whole-genome RNA interference screen for human cell factors affecting myxoma virus replication. PMID:23408614
BRAF mutation-specific promoter methylation of FOX genes in colorectal cancer. PMID:23324568
Heuristic methods for finding pathogenic variants in gene coding sequences. PMID:23316295
MicroRNA expression profiling of peripheral blood samples predicts resistance to first-line sunitinib in advanced renal cell carcinoma patients. PMID:23308047
An Oct4-Sall4-Nanog network controls developmental progression in the pre-implantation mouse embryo. PMID:23295861
Gene trees and species trees: irreconcilable differences. PMID:23281654
Detecting rare variants for psychiatric disorders using next generation sequencing: a methods primer. PMID:23250814
Drosophila protein interaction map (DPiM): a paradigm for metazoan protein complex interactions. PMID:23222005
PANTHER in 2013: modeling the evolution of gene function, and other gene attributes, in the context of phylogenetic trees. PMID:23193289
TNAP and EHD1 are over-expressed in bovine brain capillary endothelial cells after the re-induction of blood-brain barrier properties. PMID:23119012
PPARG binding landscapes in macrophages suggest a genome-wide contribution of PU.1 to divergent PPARG binding in human and mouse. PMID:23118933
Beware of Hemizygous Deletions That May Unmask Deleterious Variants. PMID:23112749
Quantitative proteomics with siRNA screening identifies novel mechanisms of trastuzumab resistance in HER2 amplified breast cancers. PMID:23105007
Global analysis of the haematopoietic and endothelial transcriptome during zebrafish development. PMID:23072875
Comparative study of human and mouse postsynaptic proteomes finds high compositional conservation and abundance differences for key synaptic proteins. PMID:23071613
E2F8 is essential for polyploidization in mammalian cells. PMID:23064264
Predicting the functional effect of amino acid substitutions and indels. PMID:23056405
Interpretation of the consequences of mutations in protein kinases: combined use of bioinformatics and text mining. PMID:23055974
Predicting the functional, molecular, and phenotypic consequences of amino acid substitutions using hidden Markov models. PMID:23033316
WaveSeq: a novel data-driven method of detecting histone modification enrichments using wavelets. PMID:23029045
Splicing switch of an epigenetic regulator by RNA helicases promotes tumor-cell invasiveness. PMID:23022728
Characterization and ligand identification of a membrane progesterone receptor in fungi: existence of a novel PAQR in Sporothrix schenckii. PMID:22958375
Effects of heat shock protein 72 (Hsp72) on evolution of astrocyte activation following stroke in the mouse. PMID:22940431
FunSAV: predicting the functional effect of single amino acid variants using a two-stage random forest model. PMID:22937107
Quantitative proteomic analysis reveals novel mitochondrial targets of estrogen deficiency in the aged female rat heart. PMID:22930739
Beta adrenergic overstimulation impaired vascular contractility via actin-cytoskeleton disorganization in rabbit cerebral artery. PMID:22916309
Changes in proteomic profiles in different prostate lobes of male rats throughout growth and development and aging stages of the life span. PMID:22911278
A Bayesian ensemble approach with a disease gene network predicts damaging effects of missense variants of human cancers. PMID:22907477
Genetic variants and haplotypes of the UGT1A9, 1A7 and 1A1 genes in Chinese Han. PMID:22888291
Proteolytic Potential of the MSC Exosome Proteome: Implications for an Exosome-Mediated Delivery of Therapeutic Proteasome. PMID:22852084
Ontogenic expression pattern and genetic polymorphisms of the fatty acid transport protein 4 (FATP4) gene in Chinese chicken populations. PMID:22837665
Biochemical and physical characterisation of urinary nanovesicles following CHAPS treatment. PMID:22808001
Regulatory element copy number differences shape primate expression profiles. PMID:22797897
ProteinHistorian: tools for the comparative analysis of eukaryote protein origin. PMID:22761559
Paneth cells in intestinal homeostasis and tissue injury. PMID:22745693
A SEL1L mutation links a canine progressive early-onset cerebellar ataxia to the endoplasmic reticulum-associated protein degradation (ERAD) machinery. PMID:22719266
Global Approaches to the Role of miRNAs in Drug-Induced Changes in Gene Expression. PMID:22707957
An interferon-related signature in the transcriptional core response of human macrophages to Mycobacterium tuberculosis infection. PMID:22675550
KD4v: Comprehensible Knowledge Discovery System for Missense Variant. PMID:22641855
Involvement of microRNA lethal-7a in the regulation of embryo implantation in mice. PMID:22623977
Computational methods to work as first-pass filter in deleterious SNP analysis of alkaptonuria. PMID:22606059
Clusters of ancestrally related genes that show paralogy in whole or in part are a major feature of the genomes of humans and other species. PMID:22563380
Proteomic analysis of wild-type and mutant huntingtin-associated proteins in mouse brains identifies unique interactions and involvement in protein synthesis. PMID:22556411
Proton radiation-induced miRNA signatures in mouse blood: characterization and comparison with 56Fe-ion and gamma radiation. PMID:22551419
A metagenomic study of diet-dependent interaction between gut microbiota and host in infants reveals differences in immune response. PMID:22546241
THINK Back: KNowledge-based Interpretation of High Throughput data. PMID:22536867
Functional organization and its implication in evolution of the human protein-protein interaction network. PMID:22530615
Proteomic profiling of the rat hypothalamus. PMID:22519962
Global gene expression profiling of human osteosarcomas reveals metastasis-associated chemokine pattern. PMID:22518090
Candidate pathway based analysis for cleft lip with or without cleft palate. PMID:22499695
Host immune transcriptional profiles reflect the variability in clinical disease manifestations in patients with Staphylococcus aureus infections. PMID:22496797
Induction of cell proliferation in old rat liver can reset certain gene expression levels characteristic of old liver to those associated with young liver. PMID:22477361
PTRF/cavin-1 and MIF proteins are identified as non-small cell lung cancer biomarkers by label-free proteomics. PMID:22461895
Transcriptome landscape of the human placenta. PMID:22448651
Evolutionary forces shaping genomic islands of population differentiation in humans. PMID:22439654
Novel polysome messages and changes in translational activity appear after induction of adipogenesis in 3T3-L1 cells. PMID:22436005
Proteomic analysis of acquired tamoxifen resistance in MCF-7 cells reveals expression signatures associated with enhanced migration. PMID:22417809
Ten years of pathway analysis: current approaches and outstanding challenges. PMID:22383865
Dysfunction of lipid sensor GPR120 leads to obesity in both mouse and human. PMID:22343897
IDH1 mutation is sufficient to establish the glioma hypermethylator phenotype. PMID:22343889
Incorporating molecular and functional context into the analysis and prioritization of human variants associated with cancer. PMID:22319177
Functional dissection of lysine deacetylases reveals that HDAC1 and p300 regulate AMPK. PMID:22318606
Candidate hippocampal biomarkers of susceptibility and resilience to stress in a rat model of depression. PMID:22311638
Nucleotide diversity of the melanocortin 1 receptor gene (MC1R) in the gayal (Bos frontalis). PMID:22307797
Copy number variation of individual cattle genomes using next-generation sequencing. PMID:22300768
Analysis of DNA sequence variants detected by high-throughput sequencing. PMID:22290882
MicroRNA alterations in Barrett's esophagus, esophageal adenocarcinoma, and esophageal adenocarcinoma cell lines following cranberry extract treatment: Insights for chemoprevention. PMID:22279419
Myeloid translocation gene 16 is required for maintenance of haematopoietic stem cell quiescence. PMID:22266796
Genetic adaptation to high altitude in the Ethiopian highlands. PMID:22264333
Tight regulation of wingless-type signaling in the articular cartilage - subchondral bone biomechanical unit: transcriptomics in Frzb-knockout mice. PMID:22264237
A combined functional annotation score for non-synonymous variants. PMID:22261837
Discovery of variants unmasked by hemizygous deletions. PMID:22258528
Bioinformatics for personal genome interpretation. PMID:22247263
Cyclophilin B expression is associated with in vitro radioresistance and clinical outcome after radiotherapy. PMID:22241958
Genome-wide analysis of N1ICD/RBPJ targets in vivo reveals direct transcriptional regulation of Wnt, SHH, and hippo pathway effectors by Notch1. PMID:22232070
The murine caecal microRNA signature depends on the presence of the endogenous microbiota. PMID:22211115
Exploration of structural stability in deleterious nsSNPs of the XPA gene: A molecular dynamics approach. PMID:22190868
E2F7 represses a network of oscillating cell cycle genes to control S-phase progression. PMID:22180533
Genome characterization of the oleaginous fungus Mortierella alpina. PMID:22174787
Genomic analysis, cytokine expression, and microRNA profiling reveal biomarkers of human dietary zinc depletion and homeostasis. PMID:22171008
Small interfering RNA against transcription factor STAT6 leads to increased cholesterol synthesis in lung cancer cell lines. PMID:22162773
AutismKB: an evidence-based knowledgebase of autism genetics. PMID:22139918
The proteome of normal pancreatic juice. PMID:22129531
Multidrug resistance-associated protein 1 (MRP1/ABCC1) polymorphism: from discovery to clinical application. PMID:22086004
RNAi screening reveals requirement for host cell secretory pathway in infection by diverse families of negative-strand RNA viruses. PMID:22065774
EcoliWiki: a wiki-based community resource for Escherichia coli. PMID:22064863
Modulation of transcriptional and inflammatory responses in murine macrophages by the Mycobacterium tuberculosis mammalian cell entry (Mce) 1 complex. PMID:22039457
A protein complex network of Drosophila melanogaster. PMID:22036573
Identification of novel NPRAP/δ-catenin-interacting proteins and the direct association of NPRAP with dynamin 2. PMID:22022388
Jarid1b targets genes regulating development and is involved in neural differentiation. PMID:22020125
A homozygous mutant embryonic stem cell bank applicable for phenotype-driven genetic screening. PMID:22020066
Sperm transcriptome profiling in oligozoospermia. PMID:21989496
Determining signalling nodes for apoptosis by a genetic high-throughput screen. PMID:21966401
Functional genomic screen and network analysis reveal novel modifiers of tauopathy dissociated from tau phosphorylation. PMID:21949350
Network analysis of quantitative proteomics on asthmatic bronchi: effects of inhaled glucocorticoid treatment. PMID:21939520
Novel germline PALB2 truncating mutations in African American breast cancer patients. PMID:21932393
Computational and statistical approaches to analyzing variants identified by exome sequencing. PMID:21920052
Quantitative proteomic identification of host factors involved in the Salmonella typhimurium infection cycle. PMID:21919203
SNP analysis of follistatin gene associated with polycystic ovarian syndrome. PMID:21918632
Protein-based signatures of functional evolution in Plasmodium falciparum. PMID:21917172
Repressor transcription factor 7-like 1 promotes adipogenic competency in precursor cells. PMID:21914845
A network-based gene-weighting approach for pathway analysis. PMID:21894192
A filter-based feature selection approach for identifying potential biomarkers for lung cancer. PMID:21884628
Combination of hydrogel nanoparticles and proteomics to reveal secreted proteins associated with decidualization of human uterine stromal cells. PMID:21884602
Cellular reprogramming by the conjoint action of ERα, FOXA1, and GATA3 to a ligand-inducible growth state. PMID:21878914
A face in the crowd: recognizing peptides through database search. PMID:21876205
Proteomic identification of novel targets regulated by the mammalian target of rapamycin pathway during oligodendrocyte differentiation. PMID:21858874
Molecular analysis of the Retinoic Acid Induced 1 gene (RAI1) in patients with suspected Smith-Magenis syndrome without the 17p11.2 deletion. PMID:21857958
Needles in stacks of needles: finding disease-causal variants in a wealth of genomic data. PMID:21850043
Comparison of human glomerulus proteomic profiles obtained from low quantities of samples by different mass spectrometry with the comprehensive database. PMID:21827715
Exploiting publicly available biological and biochemical information for the discovery of novel short linear motifs. PMID:21799808
A comparative proteome analysis links tyrosine kinase 2 (Tyk2) to the regulation of cellular glucose and lipid metabolism in response to poly(I:C). PMID:21787891
Defining genome maintenance pathways using functional genomic approaches. PMID:21787120
The InterPro BioMart: federated query and web service access to the InterPro Resource. PMID:21785143
A genome-wide association study of aging. PMID:21782286
Algal Functional Annotation Tool: a web-based analysis suite to functionally interpret large gene lists using integrated annotation and expression data. PMID:21749710
Systematic approaches towards the development of host-directed antiviral therapeutics. PMID:21747723
Calcium/calmodulin kinase1 and its relation to thermotolerance and HSP90 in Sporothrix schenckii: an RNAi and yeast two-hybrid study. PMID:21745372
KOBAS 2.0: a web server for annotation and identification of enriched pathways and diseases. PMID:21715386
Mutations in the NRG1 gene are associated with Hirschsprung disease. PMID:21706185
Regulatory link mapping between organisms. PMID:21689479
GWAS for discovery and replication of genetic loci associated with sudden cardiac arrest in patients with coronary artery disease. PMID:21658281
Discovery of the serum biomarker proteins in severe preeclampsia by proteomic analysis. PMID:21646846
Binding site prediction for protein-protein interactions and novel motif discovery using re-occurring polypeptide sequences. PMID:21635751
Cell type-specific DNA methylation at intragenic CpG islands in the immune system. PMID:21628449
In silico survey of the mitochondrial protein uptake and maturation systems in the brown alga Ectocarpus siliculosus. PMID:21611166
The transcriptome of human epicardial, mediastinal and subcutaneous adipose tissues in men with coronary artery disease. PMID:21603615
In silico tandem affinity purification refines an Oct4 interaction list. PMID:21569470
Proteomic analysis of metabolic, cytoskeletal and stress response proteins in human heart failure. PMID:21545686
Sequence variants in COL4A1 and COL4A2 genes in Ecuadorian families with keratoconus. PMID:21527998
dbNSFP: a lightweight database of human nonsynonymous SNPs and their functional predictions. PMID:21520341
Ontologies and standards in bioscience research: for machine or for human. PMID:21519400
Enabling a robust scalable manufacturing process for therapeutic exosomes through oncogenic immortalization of human ESC-derived MSCs. PMID:21513579
Identification of novel target genes of nerve growth factor (NGF) in human mastocytoma cell line (HMC-1 (V560G c-Kit)) by transcriptome analysis. PMID:21501463
Global gene expression responses to low- or high-dose radiation in a human three-dimensional tissue model. PMID:21486161
Neurons show distinctive DNA methylation profile and higher interindividual variations compared with non-neurons. PMID:21467265
Identification of differentially expressed thyroid hormone responsive genes from the brain of the Mexican Axolotl (Ambystoma mexicanum). PMID:21457787
Alignment of gene expression profiles from test samples against a reference database: New method for context-specific interpretation of microarray data. PMID:21453538
Systems analysis of endothelial cell plasma membrane proteome of rat lung microvasculature. PMID:21447187
Radiation response and regulation of apoptosis induced by a combination of TRAIL and CHX in cells lacking mitochondrial DNA: a role for NF-κB-STAT3-directed gene expression. PMID:21440540
Tyrosine phosphorylation profiling in FGF-2 stimulated human embryonic stem cells. PMID:21437283
Radiation-induced micro-RNA expression changes in peripheral blood cells of radiotherapy patients. PMID:21420249
Effect of Xpcl1 activation and p27(Kip1) loss on gene expression in murine lymphoma. PMID:21412408
A pseudo-R2 measure for selecting genomic markers with crossing hazards functions. PMID:21401964
Cranberry proanthocyanidins mediate growth arrest of lung cancer cells through modulation of gene expression and rapid induction of apoptosis. PMID:21399574
Polymorphisms of β-defensin genes in Valle del Belice dairy sheep. PMID:21390500
Prediction of in vivo radiation dose status in radiotherapy patients using ex vivo and in vivo gene expression signatures. PMID:21388269
The microRNA cluster miR-106b~25 regulates adult neural stem/progenitor cell proliferation and neuronal differentiation. PMID:21386132
Combined transcriptome analysis of fetal human and mouse cerebral cortex exposed to alcohol. PMID:21368140
Meet me halfway: when genomics meets structural bioinformatics. PMID:21350909
Swedish population substructure revealed by genome-wide single nucleotide polymorphism data. PMID:21347369
Nonsynonymous substitution rate (Ka) is a relatively consistent parameter for defining fast-evolving and slow-evolving protein-coding genes. PMID:21342519
Development and validation of a computational method for assessment of missense variants in hypertrophic cardiomyopathy. PMID:21310275
Expression profiling of major histocompatibility and natural killer complex genes reveals candidates for controlling risk of graft versus host disease. PMID:21305040
Comprehensive DNA methylation analysis of human peripheral blood leukocytes and lymphoblastoid cell lines. PMID:21304276
MTGR1 is required for tumorigenesis in the murine AOM/DSS colitis-associated carcinoma model. PMID:21303973
Molecular evolutionary analysis of ABCB5: the ancestral gene is a full transporter with potentially deleterious single nucleotide polymorphisms. PMID:21298007
Quantitative profiling of in vivo-assembled RNA-protein complexes using a novel integrated proteomic approach. PMID:21285413
Whole mouse blood microRNA as biomarkers for exposure to γ-rays and (56)Fe ion. PMID:21271940
Recent human evolution has shaped geographical differences in susceptibility to disease. PMID:21261943
Analysis of the proteome of human airway epithelial secretions. PMID:21251289
Predicting disease-associated substitution of a single amino acid by analyzing residue interactions. PMID:21223604
1,000 structures and more from the MCSG. PMID:21219649
Time-series clustering of gene expression in irradiated and bystander fibroblasts: an application of FBPA clustering. PMID:21205307
Identification of genes required for neural-specific glycosylation using functional genomics. PMID:21203496
Time-resolved quantitative proteome analysis of in vivo intestinal development. PMID:21191033
Integrative bioinformatics analysis of proteins associated with the cardiorenal syndrome. PMID:21188212
Identification of host factors involved in coronavirus replication by quantitative proteomics analysis. PMID:21182195
Genetic factors and diet affect long-bone length in the F34 LG,SM advanced intercross. PMID:21170743
Comparative analysis of the lambda-interferons IL-28A and IL-29 regarding their transcriptome and their antiviral properties against hepatitis C virus. PMID:21170333
Transcriptomic analysis of cell-free fetal RNA suggests a specific molecular phenotype in trisomy 18. PMID:21152935
Analysis of kinase gene expression patterns across 5681 human tissue samples reveals functional genomic taxonomy of the kinome. PMID:21151926
Interaction of the heterotrimeric G protein alpha subunit SSG-1 of Sporothrix schenckii with proteins related to stress response and fungal pathogenicity using a yeast two-hybrid assay. PMID:21143936
Use of cervicovaginal fluid for the identification of biomarkers for pathologies of the female genital tract. PMID:21143851
ICF syndrome in Saudi Arabia: immunological, cytogenetic and molecular analysis. PMID:21120685
Improved detection of rare genetic variants for diseases. PMID:21079782
A large-scale electrophoresis- and chromatography-based determination of gene expression profiles in bovine brain capillary endothelial cells after the re-induction of blood-brain barrier properties. PMID:21078152
Detailed analysis of function divergence in a large and diverse domain superfamily: toward a refined protocol of function classification. PMID:21070951
Whole genome co-expression analysis of soybean cytochrome P450 genes identifies nodulation-specific P450 monooxygenases. PMID:21062474
Human and chicken TLR pathways: manual curation and computer-based orthology analysis. PMID:21052677
Identification of nuclear phosphatidylinositol 4,5-bisphosphate-interacting proteins by neomycin extraction. PMID:21048195
IRF6 Screening of Syndromic and a priori Non-Syndromic Cleft Lip and Palate Patients: Identification of a New Type of Minor VWS Sign. PMID:21045959
Ubiquitin accumulation in autophagy-deficient mice is dependent on the Nrf2-mediated stress response pathway: a potential role for protein aggregation in autophagic substrate selection. PMID:21041446
Protein evolution by molecular tinkering: diversification of the nuclear receptor superfamily from a ligand-dependent ancestor. PMID:20957188
Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution. PMID:20935629
Whole-genome positive selection and habitat-driven evolution in a shallow and a deep-sea urchin. PMID:20935062
A transcriptional map of the impact of endurance exercise training on skeletal muscle phenotype. PMID:20930125
Mutations in GRIN2A and GRIN2B encoding regulatory subunits of NMDA receptors cause variable neurodevelopmental phenotypes. PMID:20890276
Research resource: transcriptome profiling of genes regulated by RXR and its permissive and nonpermissive partners in differentiating monocyte-derived dendritic cells. PMID:20861222
Impairment of circulating endothelial progenitors in Down syndrome. PMID:20836844
Functional coupling between the extracellular matrix and nuclear lamina by Wnt signaling in progeria. PMID:20833363
Cooperative and individualistic functions of the microRNAs in the miR-23a~27a~24-2 cluster and its implication in human diseases. PMID:20815877
Characterization of the proteomes associating with three distinct membrane raft sub-types in murine sperm. PMID:20815087
A genetic screen identifies the Triple T complex required for DNA damage signaling and ATM and ATR stability. PMID:20810650
The landscape of human genes involved in the immune response to parasitic worms. PMID:20807397
Proteomic analysis in multiple myeloma research. PMID:20730509
Common inherited variation in mitochondrial genes is not enriched for associations with type 2 diabetes or related glycemic traits. PMID:20714348
Quantitative proteomics discloses MET expression in mitochondria as a direct target of MET kinase inhibitor in cancer cells. PMID:20713453
Modulation of the maternal immune system by the pre-implantation embryo. PMID:20707927
Identification of essential filovirion-associated host factors by serial proteomic analysis and RNAi screen. PMID:20702783
Characterization of murine brain membrane glycoproteins by detergent assisted lectin affinity chromatography. PMID:20700909
Transcriptional profiling of intrinsic PNS factors in the postnatal mouse. PMID:20696251
Double-stranded RNAs containing multiple IU pairs are sufficient to suppress interferon induction and apoptosis. PMID:20694008
Co-expressed immune and metabolic genes in visceral and subcutaneous adipose tissue from severely obese individuals are associated with plasma HDL and glucose levels: a microarray study. PMID:20687939
The Amphimedon queenslandica genome and the evolution of animal complexity. PMID:20686567
Comparative Membranome expression analysis in primary tumors and derived cell lines. PMID:20668533
Global analysis of lysine ubiquitination by ubiquitin remnant immunoaffinity profiling. PMID:20639865
Wnt signaling regulates mitochondrial physiology and insulin sensitivity. PMID:20634317
Global regulation of alternative splicing during myogenic differentiation. PMID:20634200
Gene promoter evolution targets the center of the human protein interaction network. PMID:20628608
Activated Notch1 target genes during embryonic cell differentiation depend on the cellular context and include lineage determinants and inhibitors. PMID:20628604
Genome sequence of the necrotrophic plant pathogen Pythium ultimum reveals original pathogenicity mechanisms and effector repertoire. PMID:20626842
Tumor lymphangiogenesis and metastasis to lymph nodes induced by cancer cell expression of podoplanin. PMID:20616339
Proteomics investigation of human platelets by shotgun nUPLC-MSE and 2DE experimental strategies: a comparative study. PMID:20606744
Mutations in centrosomal protein CEP152 in primary microcephaly families linked to MCPH4. PMID:20598275
Gene expression reveals overlap between normal aging and Alzheimer's disease genes. PMID:20570407
Direct activation of forkhead box O3 by tumor suppressors p53 and p73 is disrupted during liver regeneration in mice. PMID:20564353
Morphine treatment of human monocyte-derived macrophages induces differential miRNA and protein expression: impact on inflammation and oxidative stress in the central nervous system. PMID:20564181
Gene expression patterns of dengue virus-infected children from nicaragua reveal a distinct signature of increased metabolism. PMID:20559541
Long-term modulations in the vertebral transcriptome of adolescent-stage rats exposed to binge alcohol. PMID:20554695
Proteome-wide profiling of the MCF10AT breast cancer progression model. PMID:20543960
Integrative and comparative genomics analysis of early hepatocellular carcinoma differentiated from liver regeneration in young and old. PMID:20540791
The use of orthologous sequences to predict the impact of amino acid substitutions on protein function. PMID:20523748
ITIH3 is a potential biomarker for early detection of gastric cancer. PMID:20515073
Discovering causal signaling pathways through gene-expression patterns. PMID:20494976
miR-31 functions as a negative regulator of lymphatic vascular lineage-specific differentiation in vitro and vascular development in vivo. PMID:20479124
Propagation of adipogenic signals through an epigenomic transition state. PMID:20478996
PhenoFam-gene set enrichment analysis through protein structural information. PMID:20478033
Genome-wide in silico screen for CCCH-type zinc finger proteins of Trypanosoma brucei, Trypanosoma cruzi and Leishmania major. PMID:20444260
Smooth and cardiac muscle-selective knock-out of Kruppel-like factor 4 causes postnatal death and growth retardation. PMID:20439457
Human allelic variation: perspective from protein function, structure, and evolution. PMID:20399638
A novel mutation and first report of dilated cardiomyopathy in ALG6-CDG (CDG-Ic): a case report. PMID:20398363
Growth delay of human bladder cancer cells by Prostate Stem Cell Antigen downregulation is associated with activation of immune signaling pathways. PMID:20374648
Getting started in gene orthology and functional analysis. PMID:20361041
Mutation@A Glance: an integrative web application for analysing mutations from human genetic diseases. PMID:20360267
Genomic analysis of expressed sequence tags in American black bear Ursus americanus. PMID:20338065
Serial transcriptome analysis and cross-species integration identifies centromere-associated protein E as a novel neuroblastoma target. PMID:20233875
Gene--environment-wide association studies: emerging approaches. PMID:20212493
Rhabdoid tumor: gene expression clues to pathogenesis and potential therapeutic targets. PMID:20212451
SplicerAV: a tool for mining microarray expression data for changes in RNA processing. PMID:20184770
Cell-specific determinants of peroxisome proliferator-activated receptor gamma function in adipocytes and macrophages. PMID:20176806
Genome-wide identification of susceptibility alleles for viral infections through a population genetics approach. PMID:20174570
Molecular profiling of a 6-hydroxydopamine model of Parkinson's disease. PMID:20169470
A DNA damage-activated checkpoint kinase phosphorylates tau and enhances tau-induced neurodegeneration. PMID:20159774
LMNA mutations, skeletal muscle lipid metabolism, and insulin resistance. PMID:20130076
Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes. PMID:20124223
A map of open chromatin in human pancreatic islets. PMID:20118932
Dysregulation of the PDGFRA gene causes inflow tract anomalies including TAPVR: integrating evidence from human genetics and model organisms. PMID:20071345
NetPath: a public resource of curated signal transduction pathways. PMID:20067622
A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58. PMID:20059953
PANTHER version 7: improved phylogenetic trees, orthologs and collaboration with the Gene Ontology Consortium. PMID:20015972
Evidence of the adaptive evolution of immune genes in chicken. PMID:20003477
Geographical genomics of human leukocyte gene expression variation in southern Morocco. PMID:19966804
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Epigenetic control of skull morphogenesis by histone deacetylase 8. PMID:19605684
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PANTHER pathway: an ontology-based pathway database coupled with data analysis tools. PMID:19597783
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The Gene Ontology's Reference Genome Project: a unified framework for functional annotation across species. PMID:19578431
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Pervasive positive selection on duplicated and nonduplicated vertebrate protein coding genes. PMID:18562677
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Quantitative systems-level determinants of human genes targeted by successful drugs. PMID:18083776
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Transcriptional profiling of native inner medullary collecting duct cells from rat kidney. PMID:17956998
A second generation human haplotype map of over 3.1 million SNPs. PMID:17943122
Genome-level longitudinal expression of signaling pathways and gene networks in pediatric septic shock. PMID:17932561
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Adaptive evolution of conserved noncoding elements in mammals. PMID:17845075
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Gene expression profiling and differentiation assessment in primary human hepatocyte cultures, established hepatoma cell lines, and human liver tissues. PMID:17512962
Proteomic analysis of up-regulated proteins in human promonocyte cells expressing severe acute respiratory syndrome coronavirus 3C-like protease. PMID:17407183
Host cell responses to Chlamydia pneumoniae in gamma interferon-induced persistence overlap those of productive infection and are linked to genes involved in apoptosis, cell cycle, and metabolism. PMID:17353287
PANTHER version 6: protein sequence and function evolution data with expanded representation of biological pathways. PMID:17130144
Applications for protein sequence-function evolution data: mRNA/protein expression analysis and coding SNP scoring tools. PMID:16912992
Genomic scale sub-family assignment of protein domains. PMID:16877569
SSADH variation in primates: intra- and interspecific data on a gene with a potential role in human cognitive functions. PMID:16786440
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Accurate prediction of the functional significance of single nucleotide polymorphisms and mutations in the ABCA1 gene. PMID:16429166
Avoiding inconsistencies over time and tracking difficulties in Applied Biosystems AB1700/Panther probe-to-gene annotations. PMID:16372901
Polymorphic micro-inversions contribute to the genomic variability of humans and chimpanzees. PMID:16362346
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A scan for positively selected genes in the genomes of humans and chimpanzees. PMID:15869325
FlyBase: genes and gene models. PMID:15608223
The PANTHER database of protein families, subfamilies, functions and pathways. PMID:15608197
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Assessment of genome-wide protein function classification for Drosophila melanogaster. PMID:12952880
PANTHER: a browsable database of gene products organized by biological function, using curated protein family and subfamily classification. PMID:12520017 -
Large-scale gene function analysis with the PANTHER classification system
PubMed citations: 1191.
1191 articles citing: Large-scale gene function analysis with the PANTHER classification system
Tenogenic induction of human adipose-derived stem cells by soluble tendon extracellular matrix: composition and transcriptomic analyses. PMID:35906661
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Retinal Proteomic Analysis in a Mouse Model of Endotoxin-Induced Uveitis Using Data-Independent Acquisition-Based Mass Spectrometry. PMID:35742911
The arginine methyltransferase Carm1 is necessary for heart development. PMID:35736367
Full-Length Transcriptome Sequencing Analysis of Differentially Expressed Genes and Pathways After Treatment of Psoriasis With Oxymatrine. PMID:35721124
RNA Sequencing Unveils Very Small RNAs With Potential Regulatory Functions in Bacteria. PMID:35720117
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T-cell trans-synaptic vesicles are distinct and carry greater effector content than constitutive extracellular vesicles. PMID:35710644
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Ebola Virus Encodes Two microRNAs in Huh7-Infected Cells. PMID:35563619
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Molecular Evolutionary Rate Predicts Intraspecific Genetic Polymorphism and Species-Specific Selection. PMID:35456514
Semen Modulates Cell Proliferation and Differentiation-Related Transcripts in the Pig Peri-Ovulatory Endometrium. PMID:35453814
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Human primitive mesenchymal stem cell-derived retinal progenitor cells improved neuroprotection, neurogenesis, and vision in rd12 mouse model of retinitis pigmentosa. PMID:35395806
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Icariin and Icariside II Reciprocally Stimulate Osteogenesis and Inhibit Adipogenesis of Multipotential Stromal Cells through ERK Signaling. PMID:34956384
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Transcriptomic Analysis of Human Naïve and Primed Pluripotent Stem Cells. PMID:34870839
Brain atrophy progression in Parkinson's disease is shaped by connectivity and local vulnerability. PMID:34859216
Ionizing radiations induce shared epigenomic signatures unraveling adaptive mechanisms of cancerous cell lines with or without methionine dependency. PMID:34852845
Transcriptome-Based Identification of a Functional Fasciola hepatica Carboxylesterase B. PMID:34832612
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EP300 Selectively Controls the Enhancer Landscape of MYCN-Amplified Neuroblastoma. PMID:34772733
Ex Vivo Human Colon Tissue Exposure to Pristine Graphene Activates Genes Involved in the Binding, Adhesion and Proliferation of Epithelial Cells. PMID:34768873
MicroRNA profiling in bovine serum according to the stage of Mycobacterium avium subsp. paratuberculosis infection. PMID:34735546
PANTHER: Making genome-scale phylogenetics accessible to all. PMID:34717010
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Sexually Dimorphic Transcriptomic Changes of Developing Fetal Brain Reveal Signaling Pathways and Marker Genes of Brain Cells in Domestic Pigs. PMID:34572090
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Defining Gene Functions in Tumorigenesis by Ex vivo Ablation of Floxed Alleles in Malignant Peripheral Nerve Sheath Tumor Cells. PMID:34515675
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CSF Proteomic Alzheimer's Disease-Predictive Subtypes in Cognitively Intact Amyloid Negative Individuals. PMID:34449748
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FLAME: A Web Tool for Functional and Literature Enrichment Analysis of Multiple Gene Lists. PMID:34356520
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Intergenerational effect of short-term spaceflight in mice. PMID:34278272
Bioinformatic Analysis of Temporal and Spatial Proteome Alternations During Infections. PMID:34276775
Population differentiated copy number variation of Bos taurus, Bos indicus and their African hybrids. PMID:34253178
Time course profiling of host cell response to herpesvirus infection using nanopore and synthetic long-read transcriptome sequencing. PMID:34244540
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Epigenetic inheritance of DNA methylation changes in fish living in hydrogen sulfide-rich springs. PMID:34185679
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P23 Acts as Functional RBP in the Macrophage Inflammation Response. PMID:34179071
Systemic regulation of mitochondria by germline proteostasis prevents protein aggregation in the soma of C. elegans. PMID:34172445
Time-course transcriptome analysis of host cell response to poxvirus infection using a dual long-read sequencing approach. PMID:34167576
Circulating microRNAs predispose to takotsubo syndrome following high-dose adrenaline exposure. PMID:34155498
Automated generation of context-specific gene regulatory networks with a weighted approach in Drosophila melanogaster. PMID:34123358
LncRNAs serve as novel biomarkers for diagnosis and prognosis of childhood ALL. PMID:34112247
The proteome of the human endolymphatic sac endolymph. PMID:34088924
Age-Related Alterations in the Testicular Proteome of a Non-Human Primate. PMID:34074003
Evolutionary Processes Involved in the Emergence and Expansion of an Atypical O. sativa Group in Madagascar. PMID:34014423
Integrated transcriptomic and neuroimaging brain model decodes biological mechanisms in aging and Alzheimer's disease. PMID:34002691
Identification of Long Non-coding RNA Isolated From Naturally Infected Macrophages and Associated With Bovine Johne's Disease in Canadian Holstein Using a Combination of Neural Networks and Logistic Regression. PMID:33969037
Transcranial photobiomodulation prevents PTSD-like comorbidities in rats experiencing underwater trauma. PMID:33953158
DNA damage response- and JAK-dependent regulation of PD-L1 expression in head and neck squamous cell carcinoma (HNSCC) cells exposed to 5-fluorouracil (5-FU). PMID:33951601
SWATH Based Quantitative Proteomics Reveals Significant Lipid Metabolism in Early Myopic Guinea Pig Retina. PMID:33946922
Epigenome-wide association study of kidney function identifies trans-ethnic and ethnic-specific loci. PMID:33931109
From Proteomic Mapping to Invasion-Metastasis-Cascade Systemic Biomarkering and Targeted Drugging of Mutant BRAF-Dependent Human Cutaneous Melanomagenesis. PMID:33922182
Early Post-Prandial Regulation of Protein Expression in the Midgut of Chagas Disease Vector Rhodnius prolixus Highlights New Potential Targets for Vector Control Strategy. PMID:33920371
Cellular-resolution gene expression profiling in the neonatal marmoset brain reveals dynamic species- and region-specific differences. PMID:33903237
Drosophila primary microRNA-8 encodes a microRNA-encoded peptide acting in parallel of miR-8. PMID:33892772
TCA cycle metabolic compromise due to an aberrant S-nitrosoproteome in HIV-associated neurocognitive disorder with methamphetamine use. PMID:33876414
Protein Footprinting via Covalent Protein Painting Reveals Structural Changes of the Proteome in Alzheimer's Disease. PMID:33872013
iTRAQ-Based proteomic dataset for bovine pre-ovulatory plasma and follicular fluid containing high and low Estradiol. PMID:33869699
Multi-omic analyses in Abyssinian cats with primary renal amyloid deposits. PMID:33863921
A nonviral, nonintegrating DNA nanovector platform for the safe, rapid, and persistent manufacture of recombinant T cells. PMID:33853779
Identification of methylation changes associated with positive and negative growth deviance in Gambian infants using a targeted methyl sequencing approach of genomic DNA. PMID:33842847
Ancestral plastics exposure induces transgenerational disease-specific sperm epigenome-wide association biomarkers. PMID:33841921
Organoid modeling of Zika and herpes simplex virus 1 infections reveals virus-specific responses leading to microcephaly. PMID:33838105
Protein interactome of the Cancerous Inhibitor of protein phosphatase 2A (CIP2A) in Th17 cells. PMID:33817627
Gene Set Knowledge Discovery with Enrichr. PMID:33780170
Biologically Enhanced Genome-Wide Association Study Provides Further Evidence for Candidate Loci and Discovers Novel Loci That Influence Risk of Anterior Cruciate Ligament Rupture in a Dog Model. PMID:33763109
Epigenome-wide association study of whole blood gene expression in Framingham Heart Study participants provides molecular insight into the potential role of CHRNA5 in cigarette smoking-related lung diseases. PMID:33752734
Identification of disease treatment mechanisms through the multiscale interactome. PMID:33741907
Implementation of CRISPR/Cas9 Genome Editing to Generate Murine Lung Cancer Models That Depict the Mutational Landscape of Human Disease. PMID:33738287
A KDM5-Prospero transcriptional axis functions during early neurodevelopment to regulate mushroom body formation. PMID:33729157
Plant apocarotenoid metabolism utilizes defense mechanisms against reactive carbonyl species and xenobiotics. PMID:33721895
Faecal proteomics as a novel method to study mammalian behaviour and physiology. PMID:33720532
Neoadjuvant chemoradiation alters biomarkers of anticancer immunotherapy responses in locally advanced rectal cancer. PMID:33692216
Titanium Dioxide, but Not Zinc Oxide, Nanoparticles Cause Severe Transcriptomic Alterations in T98G Human Glioblastoma Cells. PMID:33669859
MicroRNA-mRNA Networks in Pregnancy Complications: A Comprehensive Downstream Analysis of Potential Biomarkers. PMID:33669156
Identification of Predictor Genes for Feed Efficiency in Beef Cattle by Applying Machine Learning Methods to Multi-Tissue Transcriptome Data. PMID:33664767
Transcriptome analysis of ciliary-dependent MCH signaling in differentiating 3T3-L1 pre-adipocytes. PMID:33649390
Novel gene signatures for stage classification of the squamous cell carcinoma of the lung. PMID:33649335
The genome of Magnolia biondii Pamp. provides insights into the evolution of Magnoliales and biosynthesis of terpenoids. PMID:33642574
Construction and Analysis of Survival-Associated Competing Endogenous RNA Network in Lung Adenocarcinoma. PMID:33628780
Genome-wide ancestry and introgression in a Zambian baboon hybrid zone. PMID:33624366
Evaluation of the susceptibility and fatality of lung cancer patients towards the COVID-19 infection: A systemic approach through analyzing the ACE2, CXCL10 and their co-expressed genes. PMID:33585826
A Meta-Analysis of the Effects of High-LET Ionizing Radiations in Human Gene Expression. PMID:33546472
Assessing technical and biological variation in SWATH-MS-based proteomic analysis of chronic lymphocytic leukaemia cells. PMID:33536534
Neutrophil degranulation interconnects over-represented biological processes in atrial fibrillation. PMID:33536523
GeneWalk identifies relevant gene functions for a biological context using network representation learning. PMID:33526072
Cardiolipin content controls mitochondrial coupling and energetic efficiency in muscle. PMID:33523852
The role of gene to gene interaction in the breast's genomic signature of pregnancy. PMID:33514799
Targeting BET Proteins BRD2 and BRD3 in Combination with PI3K-AKT Inhibition as a Therapeutic Strategy for Ovarian Clear Cell Carcinoma. PMID:33509905
Genome-Wide Association Study of Natural Variation in Arabidopsis Exposed to Acid Mine Drainage Toxicity and Validation of Associated Genes with Reverse Genetics. PMID:33498421
Failures of nerve regeneration caused by aging or chronic denervation are rescued by restoring Schwann cell c-Jun. PMID:33475496
Age-related loss of axonal regeneration is reflected by the level of local translation. PMID:33450233
High-resolution analysis of cell-state transitions in yeast suggests widespread transcriptional tuning by alternative starts. PMID:33446241
Pathophysiological subtypes of Alzheimer's disease based on cerebrospinal fluid proteomics. PMID:33439986
Investigating the complex interplay between genotype and high-fat-diet feeding in the lactating mammary gland using the Tph1 and Ldlr knockout models. PMID:33427054
A Protein Microarray-Based Investigation of Cerebrospinal Fluid Reveals Distinct Autoantibody Signature in Low and High-Grade Gliomas. PMID:33415070
RGS2-mediated translational control mediates cancer cell dormancy and tumor relapse. PMID:33393490
Epigenome-wide association study (EWAS) for potential transgenerational disease epigenetic biomarkers in sperm following ancestral exposure to the pesticide methoxychlor. PMID:33391823
Adipose MSCs Suppress MCF7 and MDA-MB-231 Breast Cancer Metastasis and EMT Pathways Leading to Dormancy via Exosomal-miRNAs Following Co-Culture Interaction. PMID:33374139
Epigenome-wide association study for atrazine induced transgenerational DNA methylation and histone retention sperm epigenetic biomarkers for disease. PMID:33326428
PEREGRINE: A genome-wide prediction of enhancer to gene relationships supported by experimental evidence. PMID:33320871
Protein Folding Stability Changes Across the Proteome Reveal Targets of Cu Toxicity in E. coli. PMID:33305953
PANTHER version 16: a revised family classification, tree-based classification tool, enhancer regions and extensive API. PMID:33290554
Quantitative Changes in the Mitochondrial Proteome of Cerebellar Synaptosomes From Preclinical Cystatin B-Deficient Mice. PMID:33281550
An Automated Functional Annotation Pipeline That Rapidly Prioritizes Clinically Relevant Genes for Autism Spectrum Disorder. PMID:33261099
Comparative Proteomic Analysis of Walnut (Juglans regia L.) Pellicle Tissues Reveals the Regulation of Nut Quality Attributes. PMID:33261033
Putative Epigenetic Biomarkers of Stress in Red Blood Cells of Chickens Reared Across Different Biomes. PMID:33240310
Cytoplasmic mRNA recapping has limited impact on proteome complexity. PMID:33234072
Multiomic analysis identifies natural intrapatient temporal variability and changes in response to systemic corticosteroid therapy in chronic rhinosinusitis. PMID:33220024
An Investigation into Proteomic Constituents of Cerebrospinal Fluid in Patients with Chronic Peripheral Neuropathic Pain Medicated with Opioids- a Pilot Study. PMID:33219474
MicroRNA expression profiling in PBMCs of Indian water Buffalo (Bubalus bubalis) infected with Brucella and Johne's disease. PMID:33209990
Phosphorylation of Ykt6 SNARE Domain Regulates Its Membrane Recruitment and Activity. PMID:33207719
Multiplexed quantitative proteomics provides mechanistic cues for malaria severity and complexity. PMID:33204009
Genome-wide transcriptional changes triggered by water deficit on a drought-tolerant common bean cultivar. PMID:33203368
Elucidating the impact of cottonseed hydrolysates on CHO cell culture performance through transcriptomic analysis. PMID:33201275
Molecular pathophysiology of diabetes mellitus during pregnancy with antenatal complications. PMID:33184417
The PAX-FOXO1s trigger fast trans-differentiation of chick embryonic neural cells into alveolar rhabdomyosarcoma with tissue invasive properties limited by S phase entry inhibition. PMID:33175861
How to Make a Rodent Giant: Genomic Basis and Tradeoffs of Gigantism in the Capybara, the World's Largest Rodent. PMID:33169792
Epigenetic Analyses of Human Left Atrial Tissue Identifies Gene Networks Underlying Atrial Fibrillation. PMID:33155827
Epigenome-wide association study for pesticide (Permethrin and DEET) induced DNA methylation epimutation biomarkers for specific transgenerational disease. PMID:33148267
Expression profiling of cultured podocytes exposed to nephrotic plasma reveals intrinsic molecular signatures of nephrotic syndrome. PMID:33147911
Smooth muscle-derived progenitor cell myofibroblast differentiation through KLF4 downregulation promotes arterial remodeling and fibrosis. PMID:33119549
Dynamic changes in the brain protein interaction network correlates with progression of Aβ42 pathology in Drosophila. PMID:33116184
Prometheus, an omics portal for interkingdom comparative genomic analyses. PMID:33112870
Cp1/cathepsin L is required for autolysosomal clearance in Drosophila. PMID:33112206
CUX2, BRAP and ALDH2 are associated with metabolic traits in people with excessive alcohol consumption. PMID:33093602
Early Detection of Daylengths with a Feedforward Circuit Coregulated by Circadian and Diurnal Cycles. PMID:33086045
A Genome-Wide RNAi Screen for Enhancers of a Germline Tumor Phenotype Caused by Elevated GLP-1/Notch Signaling in Caenorhabditis elegans. PMID:33077477
Search and comparison of (epi)genomic feature patterns in multiple genome browser tracks. PMID:33076821
Endothelial extracellular vesicles contain protective proteins and rescue ischemia-reperfusion injury in a human heart-on-chip. PMID:33055246
Microenvironmental Hypoxia Induces Dynamic Changes in Lung Cancer Synthesis and Secretion of Extracellular Vesicles. PMID:33050615
Transgenerational disease specific epigenetic sperm biomarkers after ancestral exposure to dioxin. PMID:33039529
Differential gene expression in skin RNA of horses affected with degenerative suspensory ligament desmitis. PMID:33028365
Preoperative serum circulating microRNAs as potential biomarkers for chronic postoperative pain after total knee replacement. PMID:33021154
Sprr2f protects against renal injury by decreasing the level of reactive oxygen species in female mice. PMID:33017192
High-quality nuclear genome for Sarcoptes scabiei-A critical resource for a neglected parasite. PMID:33001992
Establishment and maintenance of motor neuron identity via temporal modularity in terminal selector function. PMID:33001031
Leveraging TCGA gene expression data to build predictive models for cancer drug response. PMID:32998700
PRINS lncRNA Is a New Biomarker Candidate for HPV Infection and Prognosis of Head and Neck Squamous Cell Carcinomas. PMID:32998396
IDPology of the living cell: intrinsic disorder in the subcellular compartments of the human cell. PMID:32997198
Genome-wide CRISPR screens of oral squamous cell carcinoma reveal fitness genes in the Hippo pathway. PMID:32990596
Differential transcription of expanded gene families in central carbon metabolism of Streptomyces coelicolor A3(2). PMID:32974587
Functional gene networks reveal distinct mechanisms segregating in migraine families. PMID:32968778
SWI/SNF complexes act through CBP-1 histone acetyltransferase to regulate acute functional tolerance to alcohol. PMID:32957927
Exploring genomic variation associated with drought stress in Picea mariana populations. PMID:32953060
Next-Generation Sequencing Characterizes the Landscape of Somatic Mutations and Pathways in Metastatic Bile Tract Carcinoma. PMID:32952556
Targeting TRIM37-driven centrosome dysfunction in 17q23-amplified breast cancer. PMID:32908313
Epigenome-wide association study for transgenerational disease sperm epimutation biomarkers following ancestral exposure to jet fuel hydrocarbons. PMID:32905848
In silico identification of common and specific signatures in coronary heart diseases. PMID:32905032
Spleen proteomics data from high fat diet fed mice. PMID:32904176
The Zebrafish Perivitelline Fluid Provides Maternally-Inherited Defensive Immunity. PMID:32899417
Mortality Risk Profiling of Staphylococcus aureus Bacteremia by Multi-omic Serum Analysis Reveals Early Predictive and Pathogenic Signatures. PMID:32888495
Between-Generation Phenotypic and Epigenetic Stability in a Clonal Snail. PMID:32877512
Enrichment of microsomes from Chinese hamster ovary cells by subcellular fractionation for its use in proteomic analysis. PMID:32841274
Arabidopsis shoot stem cells display dynamic transcription and DNA methylation patterns. PMID:32815560
Adenosine-to-Inosine Editing of Vasoactive MicroRNAs Alters Their Targetome and Function in Ischemia. PMID:32814251
Modelling the developmental spliceosomal craniofacial disorder Burn-McKeown syndrome using induced pluripotent stem cells. PMID:32735620
PiggyBac mutagenesis and exome sequencing identify genetic driver landscapes and potential therapeutic targets of EGFR-mutant gliomas. PMID:32727536
High-Throughput Identification of the Rhodnius prolixus Midgut Proteome Unravels a Sophisticated Hematophagic Machinery. PMID:32722125
Preeclamptic placentae release factors that damage neurons: implications for foetal programming of disease. PMID:32714596
Correlation of drug resistance with single nucleotide variations through genome analysis and experimental validation in a multi-drug resistant clinical isolate of M. tuberculosis. PMID:32711461
An epigenome-wide association study of ambient pyrethroid pesticide exposures in California's central valley. PMID:32679516
A high-resolution transcriptome map identifies small RNA regulation of metabolism in the gut microbe Bacteroides thetaiotaomicron. PMID:32678091
Systematic Discovery of Short Linear Motifs Decodes Calcineurin Phosphatase Signaling. PMID:32645368
Integration of Transcriptome, Gross Morphology and Histopathology in the Gill of Sea Farmed Atlantic Salmon (Salmo salar): Lessons From Multi-Site Sampling. PMID:32636874
Developmental origins of transgenerational sperm histone retention following ancestral exposures. PMID:32628935
Incorporating hybrid models into lysine malonylation sites prediction on mammalian and plant proteins. PMID:32601280
Activation of SIRT6 by DNA hypomethylating agents and clinical consequences on combination therapy in leukemia. PMID:32587297
Composition of Caenorhabditis elegans extracellular vesicles suggests roles in metabolism, immunity, and aging. PMID:32578074
Proteomics Profiling of KAIMRC1 in Comparison to MDA-MB231 and MCF-7. PMID:32570693
TMT Sample Preparation for Proteomics Facility Submission and Subsequent Data Analysis. PMID:32568242
Functional and Structural Analysis of Predicted Proteins Obtained from Homo sapiens' Minisatellite 33.15-Tagged Transcript pAKT-45 Variants. PMID:32566673
Gene Expression Profiling in Fibromyalgia Indicates an Autoimmune Origin of the Disease and Opens New Avenues for Targeted Therapy. PMID:32532082
Cell-Specific Transcriptional Responses to Heat Shock in the Mouse Utricle Epithelium. PMID:32528249
Proteomic profiling of the monothiol glutaredoxin Grx3 reveals its global role in the regulation of iron dependent processes. PMID:32525871
Transcriptome Profiling of Toxoplasma gondii-Infected Human Cerebromicrovascular Endothelial Cell Response to Treatment with Monensin. PMID:32512820
Profiling and quantification of pluripotency reprogramming reveal that WNT pathways and cell morphology have to be reprogramed extensively. PMID:32490244
Posttranslational Arginylation Enzyme Arginyltransferase1 Shows Genetic Interactions With Specific Cellular Pathways in vivo. PMID:32435206
The Effect of Bee Venom Peptides Melittin, Tertiapin, and Apamin on the Human Erythrocytes Ghosts: A Preliminary Study. PMID:32413967
Mutation severity spectrum of rare alleles in the human genome is predictive of disease type. PMID:32413045
Amyloid-beta peptide neurotoxicity in human neuronal cells is associated with modulation of insulin-like growth factor transport, lysosomal machinery and extracellular matrix receptor interactions. PMID:32394972
Heterogeneity of proteome dynamics between connective tissue phases of adult tendon. PMID:32393437
A Literature Review of Gene Function Prediction by Modeling Gene Ontology. PMID:32391061
Comprehensive Molecular Profiles of Functionally Effective MSC-Derived Extracellular Vesicles in Immunomodulation. PMID:32380062
Comprehensive proteomics and functional annotation of mouse brown adipose tissue. PMID:32374735
A Genetic Investigation of Island Jersey Cattle, the Foundation of the Jersey Breed: Comparing Population Structure and Selection to Guernsey, Holstein, and United States Jersey Cattle. PMID:32362912
Exposure to the environmental pollutant bisphenol A diglycidyl ether (BADGE) causes cell over-proliferation in Drosophila. PMID:32347502
Amyotrophic Lateral Sclerosis Modifiers in Drosophila Reveal the Phospholipase D Pathway as a Potential Therapeutic Target. PMID:32345615
Ileal Transcriptome Profiles of Japanese Quail Divergent in Phosphorus Utilization. PMID:32316159
Prostate cancer cell-intrinsic interferon signaling regulates dormancy and metastatic outgrowth in bone. PMID:32314873
Predicting Protein Functions Based on Differential Co-expression and Neighborhood Analysis. PMID:32302512
The lasting after-effects of an ancient polyploidy on the genomes of teleosts. PMID:32298330
Network Systems Pharmacology-Based Mechanism Study on the Beneficial Effects of Vitamin D against Psychosis in Alzheimer's Disease. PMID:32273551
Whole genome detection of sequence and structural polymorphism in six diverse horses. PMID:32271776
Interference With Complex IV as a Model of Age-Related Decline in Synaptic Connectivity. PMID:32265651
Characterization of Signaling Pathways Associated with Pancreatic β-cell Adaptive Flexibility in Compensation of Obesity-linked Diabetes in db/db Mice. PMID:32265294
AthCNV: A Map of DNA Copy Number Variations in the Arabidopsis Genome. PMID:32265262
Phenotypic Screening of Chemical Libraries Enriched by Molecular Docking to Multiple Targets Selected from Glioblastoma Genomic Data. PMID:32243127
Proteomic mapping of Drosophila transgenic elav.L-GAL4/+ brain as a tool to illuminate neuropathology mechanisms. PMID:32214222
Vesicles Shed by Pathological Murine Adipocytes Spread Pathology: Characterization and Functional Role of Insulin Resistant/Hypertrophied Adiposomes. PMID:32214011
Hyena paleogenomes reveal a complex evolutionary history of cross-continental gene flow between spotted and cave hyena. PMID:32201717
An array of 60,000 antibodies for proteome-scale antibody generation and target discovery. PMID:32195335
The role of semen and seminal plasma in inducing large-scale genomic changes in the female porcine peri-ovulatory tract. PMID:32193402
CIP2A Constrains Th17 Differentiation by Modulating STAT3 Signaling. PMID:32171124
A light-dependent molecular link between competition cues and defence responses in plants. PMID:32170284
DJ-1 is indispensable for the S-nitrosylation of Parkin, which maintains function of mitochondria. PMID:32152416
Transcriptome analysis of Panax ginseng response to high light stress. PMID:32148414
The mitochondrial protein PGAM5 suppresses energy consumption in brown adipocytes by repressing expression of uncoupling protein 1. PMID:32144202
An Information Entropy-Based Approach for Computationally Identifying Histone Lysine Butyrylation. PMID:32117407
Proteomic Analysis of Mucopolysaccharidosis IIIB Mouse Brain. PMID:32111039
Proteomic Analysis of Salmonella-modified Membranes Reveals Adaptations to Macrophage Hosts. PMID:32102972
A Guide to Conquer the Biological Network Era Using Graph Theory. PMID:32083072
Genetic mechanisms of formation of radiation-induced instability of the genome and its transgenerational effects in the descendants of chronically irradiated individuals of Drosophila melanogaster. PMID:32076810
Changes in the proteome of sea urchin Paracentrotus lividus coelomocytes in response to LPS injection into the body cavity. PMID:32074628
Target prediction and validation of microRNAs expressed from FSHR and aromatase genes in human ovarian granulosa cells. PMID:32042028
The differences in brain stem transcriptional profiling in hypertensive ISIAH and normotensive WAG rats. PMID:32039698
Toward a gold standard for benchmarking gene set enrichment analysis. PMID:32026945
AQP5 enriches for stem cells and cancer origins in the distal stomach. PMID:32025032
Cancer LncRNA Census reveals evidence for deep functional conservation of long noncoding RNAs in tumorigenesis. PMID:32024996
Behavioral and Transcriptional Response to Selection for Olfactory Behavior in Drosophila. PMID:32024668
Listeria monocytogenes Exploits Mitochondrial Contact Site and Cristae Organizing System Complex Subunit Mic10 To Promote Mitochondrial Fragmentation and Cellular Infection. PMID:32019800
A comparative gene co-expression analysis using self-organizing maps on two congener filmy ferns identifies specific desiccation tolerance mechanisms associated to their microhabitat preference. PMID:32019526
Genetic Networks Underlying Natural Variation in Basal and Induced Activity Levels in Drosophila melanogaster. PMID:32014853
Demonstration and Characterization of Cyst-Like Structures in the Life Cycle of Trichomonas vaginalis. PMID:32010634
Cell-Type-Specific Analysis of Molecular Pathology in Autism Identifies Common Genes and Pathways Affected Across Neocortical Regions. PMID:32008165
Inhibition of cytoplasmic cap methylation identifies 5' TOP mRNAs as recapping targets and reveals recapping sites downstream of native 5' ends. PMID:31996904
Remethylation of Dnmt3a -/- hematopoietic cells is associated with partial correction of gene dysregulation and reduced myeloid skewing. PMID:31996479
Biomarker discovery for chronic liver diseases by multi-omics - a preclinical case study. PMID:31992752
Blood and brain gene expression trajectories mirror neuropathology and clinical deterioration in neurodegeneration. PMID:31989163
A Multi-Omics Analysis of Bone Morphogenetic Protein 5 (BMP5) mRNA Expression and Clinical Prognostic Outcomes in Different Cancers Using Bioinformatics Approaches. PMID:31973134
Heating quinoa shoots results in yield loss by inhibiting fruit production and delaying maturity. PMID:31971639
Placenta-Specific Genes, Their Regulation During Villous Trophoblast Differentiation and Dysregulation in Preterm Preeclampsia. PMID:31963593
Chronotherapy of Non-Steroidal Anti-Inflammatory Drugs May Enhance Postoperative Recovery. PMID:31949183
Duodenum Intestine-Chip for preclinical drug assessment in a human relevant model. PMID:31933478
ITGB5 Plays a Key Role in Escherichia coli F4ac-Induced Diarrhea in Piglets. PMID:31921118
A dual druggable genome-wide siRNA and compound library screening approach identifies modulators of parkin recruitment to mitochondria. PMID:31911436
Profiling of lincRNAs in human pluripotent stem cell derived forebrain neural progenitor cells. PMID:31909251
Genetic disruption of slc4a10 alters the capacity for cellular metabolism and vectorial ion transport in the choroid plexus epithelium. PMID:31906971
Different transcriptional response between susceptible and resistant common carp (Cyprinus carpio) fish hints on the mechanism of CyHV-3 disease resistance. PMID:31878870
Draft Genomes of Two Artocarpus Plants, Jackfruit (A. heterophyllus) and Breadfruit (A. altilis). PMID:31878322
An Integrated Workflow for Global, Glyco-, and Phospho-proteomic Analysis of Tumor Tissues. PMID:31859488
Whole-Exome Sequencing Characterized the Landscape of Somatic Mutations and Pathways in Colorectal Cancer Liver Metastasis. PMID:31814826
Expression And Biological Interaction Network Of RHOC For Hepatic Carcinoma With Metastasis In PBMC Samples. PMID:31806997
Heterogeneity and dynamics of active Kras-induced dysplastic lineages from mouse corpus stomach. PMID:31804471
Transcriptomic responses in mouse blood during the first week after in vivo gamma irradiation. PMID:31797975
From genome to phenome: Predicting multiple cancer phenotypes based on somatic genomic alterations via the genomic impact transformer. PMID:31797588
Landscape of heart proteome changes in a diet-induced obesity model. PMID:31792287
Phenotypic proteomic profiling identifies a landscape of targets for circadian clock-modulating compounds. PMID:31792063
Predicting novel genomic regions linked to genetic disorders using GWAS and chromosome conformation data - a case study of schizophrenia. PMID:31784692
Programmed DNA elimination of germline development genes in songbirds. PMID:31784533
Fibroblastic Reticular Cells Control Conduit Matrix Deposition during Lymph Node Expansion. PMID:31775047
Global targeting of functional tyrosines using sulfur-triazole exchange chemistry. PMID:31768034
Unraveling the Adipose Tissue Proteome of Transition Cows through Severe Negative Energy Balance. PMID:31766506
Adipocyte epigenetic alterations and potential therapeutic targets in transgenerationally inherited lean and obese phenotypes following ancestral exposures. PMID:31755359
Human induced pluripotent stem cells from two azoospermic patients with Klinefelter syndrome show similar X chromosome inactivation behavior to female pluripotent stem cells. PMID:31743397
Sperm DNA Methylation Epimutation Biomarkers for Male Infertility and FSH Therapeutic Responsiveness. PMID:31727924
Characterization of the placental transcriptome through mid to late gestation in the mare. PMID:31725741
The Endophytic Fungus Chaetomium cupreum Regulates Expression of Genes Involved in the Tolerance to Metals and Plant Growth Promotion in Eucalyptus globulus Roots. PMID:31717780
Single-Cell Profiling Reveals Sex, Lineage, and Regional Diversity in the Mouse Kidney. PMID:31689386
Epigenetic transgenerational inheritance of parent-of-origin allelic transmission of outcross pathology and sperm epimutations. PMID:31682807
Transcriptome Analysis of the Hierarchical Response of Histone Deacetylase Proteins That Respond in an Antagonistic Manner to Salinity Stress. PMID:31681394
Ingestion of lean meat elevates muscle inositol hexakisphosphate kinase 1 protein content independent of a distinct post-prandial circulating proteome in young adults with obesity. PMID:31678069
Transcriptome analysis of dog oral melanoma and its oncogenic analogy with human melanoma. PMID:31661138
Molecular Mechanism of Telomere Length Dynamics and Its Prognostic Value in Pediatric Cancers. PMID:31647544
The microbiota regulate neuronal function and fear extinction learning. PMID:31645720
An in silico Approach for Integrating Phenotypic and Target-based Approaches in Drug Discovery. PMID:31638744
EV-associated miRNAs from pleural lavage as potential diagnostic biomarkers in lung cancer. PMID:31636323
MicroRNA-411 and Its 5'-IsomiR Have Distinct Targets and Functions and Are Differentially Regulated in the Vasculature under Ischemia. PMID:31636041
De novo transcriptome of Gymnema sylvestre identified putative lncRNA and genes regulating terpenoid biosynthesis pathway. PMID:31619732
Computational design and interpretation of single-RNA translation experiments. PMID:31618265
Structural, functional and molecular dynamics analysis of cathepsin B gene SNPs associated with tropical calcific pancreatitis, a rare disease of tropics. PMID:31592339
Compound Dynamics and Combinatorial Patterns of Amino Acid Repeats Encode a System of Evolutionary and Developmental Markers. PMID:31589292
Rotator Cuff Tenocytes Differentiate into Hypertrophic Chondrocyte-Like Cells to Produce Calcium Deposits in an Alkaline Phosphatase-Dependent Manner. PMID:31561454
Quantitative proteomic analysis of enhanced cellular effects of electrochemotherapy with Cisplatin in triple-negative breast cancer cells. PMID:31558821
Ash2l interacts with Oct4-stemness circuitry to promote super-enhancer-driven pluripotency network. PMID:31555818
ΔN-Tp63 Mediates Wnt/β-Catenin-Induced Inhibition of Differentiation in Basal Stem Cells of Mucociliary Epithelia. PMID:31553905
Utilization of Interspecific High-Density Genetic Map of RIL Population for the QTL Detection and Candidate Gene Mining for 100-Seed Weight in Soybean. PMID:31552060
Similarities and differences in the biotransformation and transcriptomic responses of Caenorhabditis elegans and Haemonchus contortus to five different benzimidazole drugs. PMID:31542693
Genetic lines respond uniquely within the chicken thymic transcriptome to acute heat stress and low dose lipopolysaccharide. PMID:31541148
Sex Differences in Circulating Biomarkers of Cardiovascular Disease. PMID:31537263
Physico-chemical characterization and transcriptome analysis of 5-methyltryptophan resistant lines in rice. PMID:31532784
Epigenetic transgenerational inheritance of testis pathology and Sertoli cell epimutations: generational origins of male infertility. PMID:31528361
Seed-Stored mRNAs that Are Specifically Associated to Monosomes Are Translationally Regulated during Germination. PMID:31527088
Global Transcriptomic Analysis of the Candida albicans Response to Treatment with a Novel Inhibitor of Filamentation. PMID:31511371
Functional Genomic Analyses of Exopolysaccharide-Producing Streptococcus thermophilus ASCC 1275 in Response to Milk Fermentation Conditions. PMID:31507577
Epigenetic aspects of floral homeotic genes in relation to sexual dimorphism in the dioecious plant Mercurialis annua. PMID:31504768
Molecular determinants of response to high-dose androgen therapy in prostate cancer. PMID:31503550
Palaeoproteomic identification of breast milk protein residues from the archaeological skeletal remains of a neonatal dog. PMID:31492911
Label-Free Proteomics Revealed Oxidative Stress and Inflammation as Factors That Enhance Chemoresistance in Luminal Breast Cancer. PMID:31485295
YKL-40/CHI3L1 facilitates migration and invasion in HER2 overexpressing breast epithelial progenitor cells and generates a niche for capillary-like network formation. PMID:31482369
Long Non-Coding RNAs Modulate Sjögren's Syndrome Associated Gene Expression and Are Involved in the Pathogenesis of the Disease. PMID:31480511
A Survey of Copy Number Variation in the Porcine Genome Detected From Whole-Genome Sequence. PMID:31475038
Co-culture With Human Breast Adipocytes Differentially Regulates Protein Abundance in Breast Cancer Cells. PMID:31467226
Landscape of ribosome-engaged transcript isoforms reveals extensive neuronal-cell-class-specific alternative splicing programs. PMID:31451803
Systematic Immunotherapy Target Discovery Using Genome-Scale In Vivo CRISPR Screens in CD8 T Cells. PMID:31442407
The Δ133p53β isoform promotes an immunosuppressive environment leading to aggressive prostate cancer. PMID:31431617
A Gene Expression Atlas of the Domestic Water Buffalo (Bubalus bubalis). PMID:31428126
Intrinsically disordered proteins and structured proteins with intrinsically disordered regions have different functional roles in the cell. PMID:31425549
Identification of flowering-time genes in mast flowering plants using De Novo transcriptomic analysis. PMID:31412034
Topological gene expression networks recapitulate brain anatomy and function. PMID:31410377
Fragile X mental retardation protein protects against tumour necrosis factor-mediated cell death and liver injury. PMID:31409605
CAG Repeat Not Polyglutamine Length Determines Timing of Huntington's Disease Onset. PMID:31398342
Neuroinflammatory astrocytes generated from cord blood-derived human induced pluripotent stem cells. PMID:31395092
Population-specific long-range linkage disequilibrium in the human genome and its influence on identifying common disease variants. PMID:31388069
Long Non-Coding RNAs Target Pathogenetically Relevant Genes and Pathways in Rheumatoid Arthritis. PMID:31382516
Transcriptional profiling aligned with in situ expression image analysis reveals mosaically expressed molecular markers for GABA neuron sub-groups in the ventral tegmental area. PMID:31374129
Lysine harvesting is an antioxidant strategy and triggers underground polyamine metabolism. PMID:31367038
5-hydroxymethylcytosine Marks Mammalian Origins Acting as a Barrier to Replication. PMID:31363131
The impact of DNA methylation on the cancer proteome. PMID:31356589
Circadian Regulation of Cochlear Sensitivity to Noise by Circulating Glucocorticoids. PMID:31353184
The molecular genetic make-up of male breast cancer. PMID:31340200
lncRNA expression predicts mRNA abundance. PMID:31339345
Exosomes regulate neurogenesis and circuit assembly. PMID:31320591
Disease modeling of core pre-mRNA splicing factor haploinsufficiency. PMID:31304552
High Constitutive Cytokine Release by Primary Human Acute Myeloid Leukemia Cells Is Associated with a Specific Intercellular Communication Phenotype. PMID:31277464
Identification of genes regulated by a jasmonate- and salt-inducible transcription factor JRE3 in tomato. PMID:31275046
Precise co-registration of mass spectrometry imaging, histology, and laser microdissection-based omics. PMID:31263919
Oviductal extracellular vesicles interact with the spermatozoon's head and mid-piece and improves its motility and fertilizing ability in the domestic cat. PMID:31263184
Stochastic changes in gene expression promote chaotic dysregulation of homeostasis in clonal breast tumors. PMID:31240244
Transcriptomic analysis of 3D Cardiac Differentiation of Human Induced Pluripotent Stem Cells Reveals Faster Cardiomyocyte Maturation Compared to 2D Culture. PMID:31239450
Azithromycin induces epidermal differentiation and multivesicular bodies in airway epithelia. PMID:31234850
Atlas of Subcellular RNA Localization Revealed by APEX-Seq. PMID:31230715
Immature excitatory neurons develop during adolescence in the human amygdala. PMID:31227709
Mevalonate pathway activity as a determinant of radiation sensitivity in head and neck cancer. PMID:31225926
EV-associated miRNAs from peritoneal lavage as potential diagnostic biomarkers in colorectal cancer. PMID:31221189
De Novo Assembly and Annotation of the Larval Transcriptome of Two Spadefoot Toads Widely Divergent in Developmental Rate. PMID:31217263
Unilateral L4-dorsal root ganglion stimulation evokes pain relief in chronic neuropathic postsurgical knee pain and changes of inflammatory markers: part II whole transcriptome profiling. PMID:31217010
EV-Associated miRNAs from Peritoneal Lavage are a Source of Biomarkers in Endometrial Cancer. PMID:31216648
Specific Contributions of Cohesin-SA1 and Cohesin-SA2 to TADs and Polycomb Domains in Embryonic Stem Cells. PMID:31216471
The Plant Ontology Facilitates Comparisons of Plant Development Stages Across Species. PMID:31214208
Small RNA-seq reveals novel regulatory components for apomixis in Paspalum notatum. PMID:31195966
miR-17-92 and miR-106b-25 clusters regulate beta cell mitotic checkpoint and insulin secretion in mice. PMID:31187215
Sperm epimutation biomarkers of obesity and pathologies following DDT induced epigenetic transgenerational inheritance of disease. PMID:31186947
Exploratory locomotion, a predictor of addiction vulnerability, is oligogenic in rats selected for this phenotype. PMID:31182603
Spatial proteomics reveal that the protein phosphatase PTP1B interacts with and may modify tyrosine phosphorylation of the rhomboid protease RHBDL4. PMID:31177093
Global transcriptomic analysis of the arcuate nucleus following chronic glucocorticoid treatment. PMID:31176677
PROM1 and PROM2 expression differentially modulates clinical prognosis of cancer: a multiomics analysis. PMID:31164716
RNA methyltransferase BCDIN3D is crucial for female fertility and miRNA and mRNA profiles in Drosophila ovaries. PMID:31145769
New roles for the de-ubiquitylating enzyme OTUD4 in an RNA-protein network and RNA granules. PMID:31138677
mRNA profiling reveals significant transcriptional differences between a multipotent progenitor and its differentiated sister. PMID:31138122
DDX5 plays essential transcriptional and post-transcriptional roles in the maintenance and function of spermatogonia. PMID:31123254
Differential proteome analysis in adolescent idiopathic scoliosis patients with thoracolumbar/lumbar curvatures. PMID:31122237
Metabolic reprogramming and Notch activity distinguish between non-small cell lung cancer subtypes. PMID:31114017
Engram-specific transcriptome profiling of contextual memory consolidation. PMID:31110186
Retinal Gene Distribution and Functionality Implicated in Inherited Retinal Degenerations Can Reveal Disease-Relevant Pathways for Pharmacologic Intervention. PMID:31108889
Genetics of cocaine and methamphetamine consumption and preference in Drosophila melanogaster. PMID:31107875
6mA-DNA-binding factor Jumu controls maternal-to-zygotic transition upstream of Zelda. PMID:31101825
Effects of 12 Weeks of Hypertrophy Resistance Exercise Training Combined with Collagen Peptide Supplementation on the Skeletal Muscle Proteome in Recreationally Active Men. PMID:31091754
High-Throughput Single-Cell Transcriptome Profiling of Plant Cell Types. PMID:31091459
Co-cultivation of the anaerobic fungus Anaeromyces robustus with Methanobacterium bryantii enhances transcription of carbohydrate active enzymes. PMID:31089985
Differential Effects of Influenza Virus NA, HA Head, and HA Stalk Antibodies on Peripheral Blood Leukocyte Gene Expression during Human Infection. PMID:31088926
Cell Cycle Kinase Polo Is Controlled by a Widespread 3' Untranslated Region Regulatory Sequence in Drosophila melanogaster. PMID:31085682
Big Data to the Bench: Transcriptome Analysis for Undergraduates. PMID:31074696
modEnrichr: a suite of gene set enrichment analysis tools for model organisms. PMID:31069376
Transcriptomic analysis reveals cell apoptotic signature modified by heparanase in melanoma cells. PMID:31044520
Glutamate spillover in C. elegans triggers repetitive behavior through presynaptic activation of MGL-2/mGluR5. PMID:31015396
The AKT kinase signaling network is rewired by PTEN to control proximal BCR signaling in germinal center B cells. PMID:31011187
Assessment of Glyphosate Induced Epigenetic Transgenerational Inheritance of Pathologies and Sperm Epimutations: Generational Toxicology. PMID:31011160
Oncogenic Role of ZFAS1 lncRNA in Head and Neck Squamous Cell Carcinomas. PMID:31010087
OCT4 and PAX6 determine the dual function of SOX2 in human ESCs as a key pluripotent or neural factor. PMID:30999923
Quantitative proteomic analysis of a genetically induced prostate inflammation mouse model via custom 4-plex DiLeu isobaric labeling. PMID:30995113
Extracellular Vesicle-Based Therapeutic Targeting of β-Catenin to Modulate Anticancer Immune Responses in Hepatocellular Cancer. PMID:30976743
Genomic variants identified from whole-genome resequencing of indicine cattle breeds from Pakistan. PMID:30973947
A Therapeutic Strategy for Chemotherapy-Resistant Gastric Cancer via Destabilization of Both β-Catenin and RAS. PMID:30965636
The Primary Antisense Transcriptome of Halobacterium salinarum NRC-1. PMID:30959844
HOPX Is a ZNF750 Target that Promotes Late Epidermal Differentiation. PMID:30959041
Pregnancy lipidomic profiles and DNA methylation in newborns from the CHAMACOS cohort. PMID:30956810
Physiological profile of undifferentiated bovine blastocyst-derived trophoblasts. PMID:30952696
Identification of candidate cancer predisposing variants by performing whole-exome sequencing on index patients from BRCA1 and BRCA2-negative breast cancer families. PMID:30947698
Identification, classification, and evolution of putative xylosyltransferases from algae. PMID:30941581
Deciphering the Pharmacological Mechanism of the Herb Radix Ophiopogonis in the Treatment of Nasopharyngeal Carcinoma by Integrating iTRAQ-Coupled 2-D LC-MS/MS Analysis and Network Investigation. PMID:30936832
Human Bile-Mediated Regulation of Salmonella Curli Fimbriae. PMID:30936374
The identification of differentially expressed genes between extremes of placental efficiency in maternal line gilts on day 95 of gestation. PMID:30925895
Simple Tip-Based Sample Processing Method for Urinary Proteomic Analysis. PMID:30924636
Proteomic alterations of HDL in youth with type 1 diabetes and their associations with glycemic control: a case-control study. PMID:30922315
Location dependence of the transcriptional response of a potential G-quadruplex in gene promoters under oxidative stress. PMID:30916339
Transcriptional Analysis of the Human IgE-Expressing Plasma Cell Differentiation Pathway. PMID:30915071
Improved survival prognostication of node-positive malignant melanoma patients utilizing shotgun proteomics guided by histopathological characterization and genomic data. PMID:30914758
Transcriptome-wide analysis of differentially expressed chemokine receptors, SNPs, and SSRs in the age-related macular degeneration. PMID:30894217
Regulation of Gene Expression of Methionine Sulfoxide Reductases and Their New Putative Roles in Plants. PMID:30875880
Analyzing bioactive effects of the minor hop compound xanthohumol C on human breast cancer cells using quantitative proteomics. PMID:30875365
Shotgun Proteomics of Human Dentin with Different Prefractionation Methods. PMID:30872775
Transcriptome profiling analysis reveals that CXCL2 is involved in anlotinib resistance in human lung cancer cells. PMID:30871526
Multiomics Analysis Reveals that GLS and GLS2 Differentially Modulate the Clinical Outcomes of Cancer. PMID:30871151
In Systemic Sclerosis, a Unique Long Non Coding RNA Regulates Genes and Pathways Involved in the Three Main Features of the Disease (Vasculopathy, Fibrosis and Autoimmunity) and in Carcinogenesis. PMID:30866419
Proteomic Analysis of Novel Components of Nemopilema nomurai Jellyfish Venom: Deciphering the Mode of Action. PMID:30857234
Variable outcomes of human heart attack recapitulated in genetically diverse mice. PMID:30854227
CBP and SRF co-regulate dendritic growth and synaptic maturation. PMID:30850733
RNA-seq of Isolated Chromaffin Cells Highlights the Role of Sex-Linked and Imprinted Genes in Adrenal Medulla Development. PMID:30850723
Kidney micro-organoids in suspension culture as a scalable source of human pluripotent stem cell-derived kidney cells. PMID:30846463
Making Sense of the Epigenome Using Data Integration Approaches. PMID:30837884
Microsampling Capillary Electrophoresis Mass Spectrometry Enables Single-Cell Proteomics in Complex Tissues: Developing Cell Clones in Live Xenopus laevis and Zebrafish Embryos. PMID:30827088
Proteomic analysis of cholera toxin adjuvant-stimulated human monocytes identifies Thrombospondin-1 and Integrin-β1 as strongly upregulated molecules involved in adjuvant activity. PMID:30808871
PIRSitePredict for protein functional site prediction using position-specific rules. PMID:30805646
Protocol Update for large-scale genome and gene function analysis with the PANTHER classification system (v.14.0). PMID:30804569
BRN2 suppresses apoptosis, reprograms DNA damage repair, and is associated with a high somatic mutation burden in melanoma. PMID:30804224
Comparative Analysis of Brain and Fat Body Gene Splicing Patterns in the Honey Bee, Apis mellifera. PMID:30792192
AAV9-TAZ Gene Replacement Ameliorates Cardiac TMT Proteomic Profiles in a Mouse Model of Barth Syndrome. PMID:30788385
Genetic programming of macrophages generates an in vitro model for the human erythroid island niche. PMID:30787325
Application of Data-Independent Acquisition Approach to Study the Proteome Change from Early to Later Phases of Tomato Pathogenesis Responses. PMID:30781546
Human IFIT proteins inhibit lytic replication of KSHV: A new feed-forward loop in the innate immune system. PMID:30779786
Environmental Toxicant Induced Epigenetic Transgenerational Inheritance of Prostate Pathology and Stromal-Epithelial Cell Epigenome and Transcriptome Alterations: Ancestral Origins of Prostate Disease. PMID:30778168
H3.3 K27M depletion increases differentiation and extends latency of diffuse intrinsic pontine glioma growth in vivo. PMID:30770999
Multimodal Single-Cell Analysis Reveals Physiological Maturation in the Developing Human Neocortex. PMID:30770253
Retinal-input-induced epigenetic dynamics in the developing mouse dorsal lateral geniculate nucleus. PMID:30764861
Proteome data of Anopheles stephensi salivary glands using high-resolution mass spectrometry analysis. PMID:30761337
Transcriptome dataset of trunk neural crest cells migrating along the ventral pathway of chick embryos. PMID:30761336
Macrophages restrict the nephrogenic field and promote endothelial connections during kidney development. PMID:30758286
CFP suppresses breast cancer cell growth by TES-mediated upregulation of the transcription factor DDIT3. PMID:30755730
Genetic analysis of tomato root colonization by arbuscular mycorrhizal fungi. PMID:30753410
Smp38 MAP Kinase Regulation in Schistosoma mansoni: Roles in Survival, Oviposition, and Protection Against Oxidative Stress. PMID:30733716
The developmental stage of the hematopoietic niche regulates lineage in MLL-rearranged leukemia. PMID:30728174
The effect of physiological stretch and the valvular endothelium on mitral valve proteomes. PMID:30722697
Comparative transcriptome analysis reveals new molecular pathways for cucumber genes related to sex determination. PMID:30719568
Fluctuating Light Interacts with Time of Day and Leaf Development Stage to Reprogram Gene Expression. PMID:30718349
Leukocyte expression profiles reveal gene sets with prognostic value for seizure-free outcome following stereotactic laser amygdalohippocampotomy. PMID:30705324
Calcium-Phosphate Crystals Promote RANKL Expression via the Downregulation of DUSP1. PMID:30703868
Combined treatment with HMGN1 and anti-CD4 depleting antibody reverses T cell exhaustion and exerts robust anti-tumor effects in mice. PMID:30696484
Expression of Immune Regulatory Genes in the Porcine Internal Genital Tract Is Differentially Triggered by Spermatozoa and Seminal Plasma. PMID:30691059
Chromosome conformation capture resolved near complete genome assembly of broomcorn millet. PMID:30683940
Multiple genomic copy number variants associated with periventricular nodular heterotopia indicate extreme genetic heterogeneity. PMID:30683929
A Combined Targeted and Whole Exome Sequencing Approach Identified Novel Candidate Genes Involved in Heritable Pulmonary Arterial Hypertension. PMID:30679663
Robust in-silico identification of Cancer Cell Lines based on RNA and targeted DNA sequencing data. PMID:30674903
Neurons with Complex Karyotypes Are Rare in Aged Human Neocortex. PMID:30673605
A CATH domain functional family based approach to identify putative cancer driver genes and driver mutations. PMID:30670742
O-glycans truncation modulates gastric cancer cell signaling and transcription leading to a more aggressive phenotype. PMID:30662000
An interaction-based model for neuropsychiatric features of copy-number variants. PMID:30653500
The Role of Dimethyl Sulfoxide (DMSO) in Gene Expression Modulation and Glycosaminoglycan Metabolism in Lysosomal Storage Disorders on an Example of Mucopolysaccharidosis. PMID:30646511
Identification of Chondrocyte Genes and Signaling Pathways in Response to Acute Joint Inflammation. PMID:30643177
Protein Profiling of Arabidopsis Roots Treated With Humic Substances: Insights Into the Metabolic and Interactome Networks. PMID:30619394
Macrophages attenuate the transcription of CYP1A1 in breast tumor cells and enhance their proliferation. PMID:30615637
A Sam68-dependent alternative splicing program shapes postsynaptic protein complexes. PMID:30589479
Nucleoredoxin-Dependent Targets and Processes in Neuronal Cells. PMID:30584462
SCL/TAL1 cooperates with Polycomb RYBP-PRC1 to suppress alternative lineages in blood-fated cells. PMID:30560907
Transcriptional and Small RNA Responses of the White Mold Fungus Sclerotinia sclerotiorum to Infection by a Virulence-Attenuating Hypovirus. PMID:30558121
The AREB1 Transcription Factor Influences Histone Acetylation to Regulate Drought Responses and Tolerance in Populus trichocarpa. PMID:30538157
The draft genomes of five agriculturally important African orphan crops. PMID:30535374
Proteome modifications on tomato under extreme high light induced-stress. PMID:30534005
A map of constrained coding regions in the human genome. PMID:30531870
Unveiling the Role of the Most Impactful Cardiovascular Risk Locus through Haplotype Editing. PMID:30528432
PaDuA: A Python Library for High-Throughput (Phospho)proteomics Data Analysis. PMID:30525654
Specific MHC-I Peptides Are Induced Using PROTACs. PMID:30524438
The comparative analysis of phenotypic and whole transcriptome gene expression data of ascites susceptible versus ascites resistant chickens. PMID:30519813
Glucose intake hampers PKA-regulated HSP90 chaperone activity. PMID:30516470
Genomic identification and functional analysis of essential genes in Caenorhabditis elegans. PMID:30514206
Chromatogram libraries improve peptide detection and quantification by data independent acquisition mass spectrometry. PMID:30510204
Rapid niche expansion by selection on functional genomic variation after ecosystem recovery. PMID:30510178
Developmental origins of transgenerational sperm DNA methylation epimutations following ancestral DDT exposure. PMID:30500333
Functional Analysis and Fine Mapping of the 9p22.2 Ovarian Cancer Susceptibility Locus. PMID:30487138
Dosage Compensation and Gene Expression of the X Chromosome in Sheep. PMID:30482800
Reduced plasma levels of small HDL particles transporting fibrinolytic proteins in pulmonary arterial hypertension. PMID:30478197
Chronic platelet-derived growth factor receptor signaling exerts control over initiation of protein translation in glioma. PMID:30456354
Spen limits intestinal stem cell self-renewal. PMID:30452449
Genome-wide analysis reveals the evolution and structural features of WRINKLED1 in plants. PMID:30446819
lncRNA Expression after Irradiation and Chemoexposure of HNSCC Cell Lines. PMID:30441874
Contribution of Host Genetics to the Variation of Microbial Composition of Cecum Lumen and Feces in Pigs. PMID:30429843
Label-Free Quantitative Proteomics in a Methylmalonyl-CoA Mutase-Silenced Neuroblastoma Cell Line. PMID:30428564
Computational prediction of miRNAs in Nipah virus genome reveals possible interaction with human genes involved in encephalitis. PMID:30426028
MRG-1/MRG15 Is a Barrier for Germ Cell to Neuron Reprogramming in Caenorhabditis elegans. PMID:30425042
PANTHER version 14: more genomes, a new PANTHER GO-slim and improvements in enrichment analysis tools. PMID:30407594
A Screen Using iPSC-Derived Hepatocytes Reveals NAD+ as a Potential Treatment for mtDNA Depletion Syndrome. PMID:30404003
Exploring the genetic basis of gene transcript abundance and metabolite levels in loblolly pine (Pinus taeda L.) using association mapping and network construction. PMID:30400815
GnRH antagonist treatment of malignant adrenocortical tumors. PMID:30400009
The Lysosomal Transcription Factor TFEB Represses Myelination Downstream of the Rag-Ragulator Complex. PMID:30399334
Tandem Repeats Contribute to Coding Sequence Variation in Bumblebees (Hymenoptera: Apidae). PMID:30398620
A Systems-Level Analysis of Mechanisms of Platycodon grandiflorum Based on A Network Pharmacological Approach. PMID:30388815
The proteomic and metabolomic characterization of exercise-induced sweat for human performance monitoring: A pilot investigation. PMID:30383773
Identification of a Specific Translational Machinery via TCTP-EF1A2 Interaction Regulating NF1-associated Tumor Growth by Affinity Purification and Data-independent Mass Spectrometry Acquisition (AP-DIA). PMID:30381327
Experimental ischaemic stroke induces transient cardiac atrophy and dysfunction. PMID:30378296
The anticancer mechanism investigation of Tanshinone IIA by pharmacological clustering in protein network. PMID:30373594
Canonical and single-cell Hi-C reveal distinct chromatin interaction sub-networks of mammalian transcription factors. PMID:30359306
Case studies on potential G-quadruplex-forming sequences from the bacterial orders Deinococcales and Thermales derived from a survey of published genomes. PMID:30356061
Driver mutations in Janus kinases in a mouse model of B-cell leukemia induced by deletion of PU.1 and Spi-B. PMID:30355579
Lipoteichoic acid anchor triggers Mincle to drive protective immunity against invasive group A Streptococcus infection. PMID:30352847
The yellowtail (Seriola quinqueradiata) genome and transcriptome atlas of the digestive tract. PMID:30329019
Microglia innately develop within cerebral organoids. PMID:30301888
Transcriptional profiling of embryos lacking the lipoprotein receptor SR-B1 reveals a regulatory circuit governing a neurodevelopmental or metabolic decision during neural tube closure. PMID:30290792
Gene ontology enrichment analysis of congenital diaphragmatic hernia-associated genes. PMID:30287891
In Search of Biomarkers for Pathogenesis and Control of Leishmaniasis by Global Analyses of Leishmania-Infected Macrophages. PMID:30283744
SUMO-Targeted Ubiquitin Ligases (STUbLs) Reduce the Toxicity and Abnormal Transcriptional Activity Associated With a Mutant, Aggregation-Prone Fragment of Huntingtin. PMID:30279700
Protein Profile of Blood Monocytes is Altered in HTLV-1 Infected Patients: Implications for HAM/TSP Disease. PMID:30254298
Mapping of histone-binding sites in histone replacement-completed spermatozoa. PMID:30250204
Organophosphate pesticide exposure and differential genome-wide DNA methylation. PMID:30248838
Multi-Step Regulation of the TLR4 Pathway by the miR-125a~99b~let-7e Cluster. PMID:30245693
Examining the Roles of H3K4 Methylation States with Systematically Characterized Antibodies. PMID:30244833
Impact of vitamin D depletion during development on mouse sperm DNA methylation. PMID:30239288
A Human Adult Stem Cell Signature Marks Aggressive Variants across Epithelial Cancers. PMID:30232014
Regional Differences in mRNA and lncRNA Expression Profiles in Non-Failing Human Atria and Ventricles. PMID:30224797
Proteome data of Anopheles stephensi ovary using high-resolution mass spectrometry. PMID:30211266
Environmental toxicant induced epigenetic transgenerational inheritance of ovarian pathology and granulosa cell epigenome and transcriptome alterations: ancestral origins of polycystic ovarian syndrome and primary ovarian insufiency. PMID:30207508
Evaluation of dehydrated human umbilical cord biological properties for wound care and soft tissue healing. PMID:30199609
Transcriptomic Analysis Reveals Sex-Dependent Expression Patterns in the Basolateral Amygdala of Dominant and Subordinate Animals After Acute Social Conflict. PMID:30196395
Neuronal microRNA regulation in Experimental Autoimmune Encephalomyelitis. PMID:30194392
A rationally designed JAZ subtype-selective agonist of jasmonate perception. PMID:30194307
Rare variants in the genetic background modulate cognitive and developmental phenotypes in individuals carrying disease-associated variants. PMID:30190612
Transcriptome analysis of immune genes in peripheral blood mononuclear cells of young foals and adult horses. PMID:30183726
iTRAQ-based analysis of sperm proteome from normozoospermic men achieving the rescue-ICSI pregnancy after the IVF failure. PMID:30166971
Integrated analysis of dysregulated lncRNA expression in breast cancer cell identified by RNA-seq study. PMID:30159409
A genome-wide association study for harness racing success in the Norwegian-Swedish coldblooded trotter reveals genes for learning and energy metabolism. PMID:30157760
Vinclozolin induced epigenetic transgenerational inheritance of pathologies and sperm epimutation biomarkers for specific diseases. PMID:30157260
Changes in proteome solubility indicate widespread proteostatic disruption in mouse models of neurodegenerative disease. PMID:30140941
Sm-p80-based schistosomiasis vaccine: double-blind preclinical trial in baboons demonstrates comprehensive prophylactic and parasite transmission-blocking efficacy. PMID:30133707
Functional Interactions Between rsks-1/S6K, glp-1/Notch, and Regulators of Caenorhabditis elegans Fertility and Germline Stem Cell Maintenance. PMID:30126834
Silence is golden: gene silencing of V. cholerae during intestinal colonization delivers new aspects to the acid tolerance response. PMID:30110191
Genomic landscape and mutational impacts of recurrently mutated genes in cancers. PMID:30107644
Nuclear localized Raf1 isoform alters DNA-dependent protein kinase activity and the DNA damage response. PMID:30106602
Genomewide Association Study of Leisure-Time Exercise Behavior in Japanese Adults. PMID:30102679
Comparative proteomic analysis of QTL CTS-12 derived from wild rice (Oryza rufipogon Griff.), in the regulation of cold acclimation and de-acclimation of rice (Oryza sativa L.) in response to severe chilling stress. PMID:30097068
Precardiac organoids form two heart fields via Bmp/Wnt signaling. PMID:30087351
FACT Sets a Barrier for Cell Fate Reprogramming in Caenorhabditis elegans and Human Cells. PMID:30078731
Understanding Ovarian Cancer: iTRAQ-Based Proteomics for Biomarker Discovery. PMID:30065196
Pooled genome-wide CRISPR screening for basal and context-specific fitness gene essentiality in Drosophila cells. PMID:30051818
The Role of m6A/m-RNA Methylation in Stress Response Regulation. PMID:30048615
Calcium-binding proteins that are type B″ regulatory subunits of phosphatase 2A in Giardia intestinalis. PMID:30043281
A comparison of heat-stress transcriptome changes between wild-type Arabidopsis pollen and a heat-sensitive mutant harboring a knockout of cyclic nucleotide-gated cation channel 16 (cngc16). PMID:30041596
Translational proteomic study to address host protein changes during aspergillosis. PMID:30040865
Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals. PMID:30038396
Genomic Prediction of Breeding Values Using a Subset of SNPs Identified by Three Machine Learning Methods. PMID:30023001
Regulation of the interferon-gamma (IFN-γ) pathway by p63 and Δ133p53 isoform in different breast cancer subtypes. PMID:30018742
Seasonal Growth of Zygophyllum dumosum Boiss.: Summer Dormancy Is Associated with Loss of the Permissive Epigenetic Marker Dimethyl H3K4 and Extensive Reduction in Proteins Involved in Basic Cell Functions. PMID:30011962
PPARγ is a nexus controlling alternative activation of macrophages via glutamine metabolism. PMID:30006480
Global phosphoproteomics of CCR5-tropic HIV-1 signaling reveals reprogramming of cellular protein production pathways and identifies p70-S6K1 and MK2 as HIV-responsive kinases required for optimal infection of CD4+ T cells. PMID:29970186
Genome-scale analysis identifies paralog lethality as a vulnerability of chromosome 1p loss in cancer. PMID:29955178
Impact of RNA integrity and blood sample storage conditions on the gene expression analysis. PMID:29950862
Idiopathic Scoliosis Families Highlight Actin-Based and Microtubule-Based Cellular Projections and Extracellular Matrix in Disease Etiology. PMID:29930198
Plasma disturbance of phospholipid metabolism in major depressive disorder by integration of proteomics and metabolomics. PMID:29922061
Local and global influences on protein turnover in neurons and glia. PMID:29914620
Proteome data of Anopheles stephensi hemolymph using high resolution mass spectrometry. PMID:29900324
Enteric bacteria boost defences against oxidative stress in Entamoeba histolytica. PMID:29899530
Eccrine Sweat as a Biofluid for Profiling Immune Biomarkers. PMID:29882373
PRDM16 isoforms differentially regulate normal and leukemic hematopoiesis and inflammatory gene signature. PMID:29878897
Probing seco-steroid inhibition of the hedgehog signaling pathway. PMID:29876765
Regulation of Mesenchymal Stem to Transit-Amplifying Cell Transition in the Continuously Growing Mouse Incisor. PMID:29874594
Altered microRNA expression signature in Chikungunya-infected mammalian fibroblast cells. PMID:29872954
Expanding the horizons of microRNA bioinformatics. PMID:29871895
Progressive Recruitment of Mesenchymal Progenitors Reveals a Time-Dependent Process of Cell Fate Acquisition in Mouse and Human Nephrogenesis. PMID:29870722
The proteome of perilymph in patients with vestibular schwannoma. A possibility to identify biomarkers for tumor associated hearing loss? PMID:29856847
Notch2 and Proteomic Signatures in Mouse Neointimal Lesion Formation. PMID:29853569
p53 Mediates Vast Gene Expression Changes That Contribute to Poor Chemotherapeutic Response in a Mouse Model of Breast Cancer. PMID:29852458
Collaborative repressive action of the antagonistic ETS transcription factors Pointed and Yan fine-tunes gene expression to confer robustness in Drosophila. PMID:29848501
Early transcriptional response of human ovarian and fallopian tube surface epithelial cells to norepinephrine. PMID:29844388
The cyclin-dependent kinase inhibitor flavopiridol (alvocidib) inhibits metastasis of human osteosarcoma cells. PMID:29805751
Evaluating recovery potential of the northern white rhinoceros from cryopreserved somatic cells. PMID:29798851
Characterization of smooth muscle cells from human atherosclerotic lesions and their responses to Notch signaling. PMID:29795127
The modulation of acetic acid pathway genes in Arabidopsis improves survival under drought stress. PMID:29777132
FACS-Seq analysis of Pax3-derived cells identifies non-myogenic lineages in the embryonic forelimb. PMID:29769607
O-GlcNAc transferase missense mutations linked to X-linked intellectual disability deregulate genes involved in cell fate determination and signaling. PMID:29769320
Ablation of Sirtuin5 in the postnatal mouse heart results in protein succinylation and normal survival in response to chronic pressure overload. PMID:29769314
Navigating Xenbase: An Integrated Xenopus Genomics and Gene Expression Database. PMID:29761462
Chemokine C-C motif ligand 33 is a key regulator of teleost fish barbel development. PMID:29760055
Proteomic Investigation to Identify Anticancer Targets of Nemopilema nomurai Jellyfish Venom in Human Hepatocarcinoma HepG2 Cells. PMID:29748501
Gene Expression in Parp1 Deficient Mice Exposed to a Median Lethal Dose of Gamma Rays. PMID:29746213
Diverse reprogramming codes for neuronal identity. PMID:29743677
CD8 Follicular T Cells Promote B Cell Antibody Class Switch in Autoimmune Disease. PMID:29743314
Mycoplasma hyorhinis reduces sensitivity of human lung carcinoma cells to Nutlin-3 and promotes their malignant phenotype. PMID:29737431
Alterations in sperm DNA methylation, non-coding RNA expression, and histone retention mediate vinclozolin-induced epigenetic transgenerational inheritance of disease. PMID:29732173
Inhibition of miR-486 and miR-92a decreases liver and plasma cholesterol levels by modulating lipid-related genes in hyperlipidemic hamsters. PMID:29725814
Prognosis of ovarian cancer is associated with effector memory CD8+ T cell accumulation in ascites, CXCL9 levels and activation-triggered signal transduction in T cells. PMID:29721385
Adar3 Is Involved in Learning and Memory in Mice. PMID:29719497
Improved strategy for the curation and classification of kinases, with broad applicability to other eukaryotic protein groups. PMID:29717207
Click Chemistry-mediated Biotinylation Reveals a Function for the Protease BACE1 in Modulating the Neuronal Surface Glycoproteome. PMID:29716987
Increased chemical acetylation of peptides and proteins in rats after daily ingestion of diacetyl analyzed by Nano-LC-MS/MS. PMID:29713565
Sensing the cilium, digital capture of ciliary data for comparative genomics investigations. PMID:29713460
Functional and structural characterization of osteocytic MLO-Y4 cell proteins encoded by genes differentially expressed in response to mechanical signals in vitro. PMID:29712973
Chromatin conformation regulates the coordination between DNA replication and transcription. PMID:29686321
Novel Plasma Proteins in Nepalese School-aged Children are Associated with a Small Head Size at Birth. PMID:29686285
Systemic surfaceome profiling identifies target antigens for immune-based therapy in subtypes of advanced prostate cancer. PMID:29686080
Stability and Function of Hippocampal Mossy Fiber Synapses Depend on Bcl11b/Ctip2. PMID:29674952
Comparative transcriptome analysis to investigate the potential role of miRNAs in milk protein/fat quality. PMID:29674689
Donor-dependent variation of human umbilical cord blood mesenchymal stem cells in response to hypoxic preconditioning and amelioration of limb ischemia. PMID:29674661
Cellular and Molecular Responses of Dunaliella tertiolecta by Expression of a Plant Medium Chain Length Fatty Acid Specific Acyl-ACP Thioesterase. PMID:29670594
Phosphoproteomic insights into processes influenced by the kinase-like protein DIA1/C3orf58. PMID:29666759
Identification of H2O2 induced oxidative stress associated microRNAs in HLE-B3 cells and their clinical relevance to the progression of age-related nuclear cataract. PMID:29653565
Phosphoproteome dynamics during mitotic exit in budding yeast. PMID:29650682
Gene-level differential analysis at transcript-level resolution. PMID:29650040
Bioinformatic analysis reveals the key pathways and genes in early-onset breast cancer. PMID:29644522
Biological signaling pathways and potential mathematical network representations: biological discovery through optimization. PMID:29635835
Identification of an Unfavorable Immune Signature in Advanced Lung Tumors from Nrf2-Deficient Mice. PMID:29634345
HLA ligandome analysis of primary chronic lymphocytic leukemia (CLL) cells under lenalidomide treatment confirms the suitability of lenalidomide for combination with T-cell-based immunotherapy. PMID:29632711
Klf4 has an unexpected protective role in perivascular cells within the microvasculature. PMID:29631369
Single-molecule, full-length transcript sequencing provides insight into the extreme metabolism of the ruby-throated hummingbird Archilochus colubris. PMID:29618047
The impact of circulating preeclampsia-associated extracellular vesicles on the migratory activity and phenotype of THP-1 monocytic cells. PMID:29615814
Gon4l regulates notochord boundary formation and cell polarity underlying axis extension by repressing adhesion genes. PMID:29615614
Identification of long-lived synaptic proteins by proteomic analysis of synaptosome protein turnover. PMID:29610302
Maternal Choline Supplementation during Normal Murine Pregnancy Alters the Placental Epigenome: Results of an Exploratory Study. PMID:29597262
Epigenetic Transgenerational Inheritance of Altered Sperm Histone Retention Sites. PMID:29593303
Preferential retention of genes from one parental genome after polyploidy illustrates the nature and scope of the genomic conflicts induced by hybridization. PMID:29590103
Proteins involved in embryo-maternal interaction around the signalling of maternal recognition of pregnancy in the horse. PMID:29588480
The Pancreatic Cancer Microbiome Promotes Oncogenesis by Induction of Innate and Adaptive Immune Suppression. PMID:29567829
Expression profiling of disease progression in canine model of Duchenne muscular dystrophy. PMID:29554127
Distinct signalling properties of insulin receptor substrate (IRS)-1 and IRS-2 in mediating insulin/IGF-1 action. PMID:29550500
Secretome analysis of rat osteoblasts during icariin treatment induced osteogenesis. PMID:29532868
Reproducible proteomics sample preparation for single FFPE tissue slices using acid-labile surfactant and direct trypsinization. PMID:29527141
A kinome-wide RNAi screen identifies ALK as a target to sensitize neuroblastoma cells for HDAC8-inhibitor treatment. PMID:29515255
Insights into the ubiquitin-proteasome system of human embryonic stem cells. PMID:29511261
Streptococcus pyogenes Infection and the Human Proteome with a Special Focus on the Immunoglobulin G-cleaving Enzyme IdeS. PMID:29511047
Alterations in sperm DNA methylation, non-coding RNA and histone retention associate with DDT-induced epigenetic transgenerational inheritance of disease. PMID:29482626
Comparative and network-based proteomic analysis of low dose ethanol- and lipopolysaccharide-induced macrophages. PMID:29481576
Proteomic profiling of extracellular vesicles released from vascular smooth muscle cells during initiation of phosphate-induced mineralization. PMID:29471680
Proteomic analysis of the human retina reveals region-specific susceptibilities to metabolic- and oxidative stress-related diseases. PMID:29466423
The Alternative NF-κB Pathway in Regulatory T Cell Homeostasis and Suppressive Function. PMID:29459403
Ixr1 Regulates Ribosomal Gene Transcription and Yeast Response to Cisplatin. PMID:29449612
Conserved and Divergent Features of Mesenchymal Progenitor Cell Types within the Cortical Nephrogenic Niche of the Human and Mouse Kidney. PMID:29449449
Transcriptome variations among human embryonic stem cell lines are associated with their differentiation propensity. PMID:29444173
Inorganic Polyphosphate Is Essential for Salmonella Typhimurium Virulence and Survival in Dictyostelium discoideum. PMID:29441327
Phosphoproteomic analysis of the antitumor effects of ginsenoside Rg3 in human breast cancer cells. PMID:29435015
Overexpression of PGC-1α in aging muscle enhances a subset of young-like molecular patterns. PMID:29427317
Dissecting the biochemical architecture and morphological release pathways of the human platelet extracellular vesiculome. PMID:29427073
Retinal genes are differentially expressed in areas of primary versus secondary degeneration following partial optic nerve injury. PMID:29425209
Proteomic profiling of antibody-inducing immunogens in tumor tissue identifies PSMA1, LAP3, ANXA3, and maspin as colon cancer markers. PMID:29423100
Clptm1 Limits Forward Trafficking of GABAA Receptors to Scale Inhibitory Synaptic Strength. PMID:29395912
MGAT1 and Complex N-Glycans Regulate ERK Signaling During Spermatogenesis. PMID:29386567
Synthetic MicroProteins: Versatile Tools for Posttranslational Regulation of Target Proteins. PMID:29382693
Development of a Photo-Cross-Linkable Diaminoquinazoline Inhibitor for Target Identification in Plasmodium falciparum. PMID:29377668
Identification of a Common Different Gene Expression Signature in Ischemic Cardiomyopathy. PMID:29361784
Systems-level mechanisms of action of Panax ginseng: a network pharmacological approach. PMID:29348728
Novel Myopia Genes and Pathways Identified From Syndromic Forms of Myopia. PMID:29346494
∆133p53 isoform promotes tumour invasion and metastasis via interleukin-6 activation of JAK-STAT and RhoA-ROCK signalling. PMID:29343721
Single-cell transcriptomics of the developing lateral geniculate nucleus reveals insights into circuit assembly and refinement. PMID:29343640
Changes in the secretome of tri-dimensional spheroid-cultured human mesenchymal stem cells in vitro by interleukin-1 priming. PMID:29343288
Biomechanical Rigidity and Quantitative Proteomics Analysis of Segmental Regions of the Trabecular Meshwork at Physiologic and Elevated Pressures. PMID:29340639
Genomic Identification and Functional Characterization of Essential Genes in Caenorhabditis elegans. PMID:29339407
Enhanced MYC association with the NuA4 histone acetyltransferase complex mediated by the adenovirus E1A N-terminal domain activates a subset of MYC target genes highly expressed in cancer cells. PMID:29321817
Thyroid transcriptome analysis reveals different adaptive responses to cold environmental conditions between two chicken breeds. PMID:29320582
Inflammatory Proteomic Network Analysis of Statin-treated and Lipopolysaccharide-activated Macrophages. PMID:29317699
Reconstructing differentiation networks and their regulation from time series single-cell expression data. PMID:29317474
Characterization of a FOXG1:TLE1 transcriptional network in glioblastoma-initiating cells. PMID:29316219
Overexpression of Human-Derived DNMT3A Induced Intergenerational Inheritance of Active DNA Methylation Changes in Rat Sperm. PMID:29312436
De novo transcriptome assembly, annotation and comparison of four ecological and evolutionary model salmonid fish species. PMID:29310597
Dissection of affinity captured LINE-1 macromolecular complexes. PMID:29309035
A High-Resolution Proteomic Landscaping of Primary Human Dental Stem Cells: Identification of SHED- and PDLSC-Specific Biomarkers. PMID:29304003
Programming of Cell Resistance to Genotoxic and Oxidative Stress. PMID:29301323
Biomarkers for tissue engineering of the tendon-bone interface. PMID:29298298
Gene regulation and suppression of type I interferon signaling by STAT3 in diffuse large B cell lymphoma. PMID:29295936
Identification of genes highly downregulated in pancreatic cancer through a meta-analysis of microarray datasets: implications for discovery of novel tumor-suppressor genes and therapeutic targets. PMID:29288362
NGS Reveals Molecular Pathways Affected by Obesity and Weight Loss-Related Changes in miRNA Levels in Adipose Tissue. PMID:29280944
Age-related inflammatory bone marrow microenvironment induces ineffective erythropoiesis mimicking del(5q) MDS. PMID:29263441
The retina/RPE proteome in chick myopia and hyperopia models: Commonalities with inherited and age-related ocular pathologies. PMID:29259393
Transcriptome analysis of ruminal epithelia revealed potential regulatory mechanisms involved in host adaptation to gradual high fermentable dietary transition in beef cattle. PMID:29258446
Fine regulation of ARF17 for anther development and pollen formation. PMID:29258431
Biotinylation by antibody recognition-a method for proximity labeling. PMID:29256494
The RNA-Binding Protein hnRNP K Mediates the Effect of BDNF on Dendritic mRNA Metabolism and Regulates Synaptic NMDA Receptors in Hippocampal Neurons. PMID:29255796
Evolutionary transition from blood feeding to obligate nonbiting in a mosquito. PMID:29255013
A comprehensive genomic meta-analysis identifies confirmatory role of OBSCN gene in breast tumorigenesis. PMID:29254242
Constitutively elevated levels of SOCS1 suppress innate responses in DF-1 immortalised chicken fibroblast cells. PMID:29235573
Genome-Wide Profiling Reveals That Herbal Medicine Jinfukang-Induced Polyadenylation Alteration Is Involved in Anti-Lung Cancer Activity. PMID:29234412
The Human Blood-Nerve Barrier Transcriptome. PMID:29234067
Identification of a gene signature for discriminating metastatic from primary melanoma using a molecular interaction network approach. PMID:29229936
A proteolytic fragment of histone deacetylase 4 protects the heart from failure by regulating the hexosamine biosynthetic pathway. PMID:29227474
Vulvar squamous cell carcinoma aggressiveness is associated with differential expression of collagen and STAT1. PMID:29225558
YY1 Is a Structural Regulator of Enhancer-Promoter Loops. PMID:29224777
Model-based genome-wide determination of RNA chain elongation rates in Escherichia coli. PMID:29222445
Madeiran Arabidopsis thaliana Reveals Ancient Long-Range Colonization and Clarifies Demography in Eurasia. PMID:29216397
Migration-Selection Balance Drives Genetic Differentiation in Genes Associated with High-Altitude Function in the Speckled Teal (Anas flavirostris) in the Andes. PMID:29211852
Single-cell RNA-Seq analysis reveals dynamic trajectories during mouse liver development. PMID:29202695
Development and differentiation of early innate lymphoid progenitors. PMID:29183988
Genome-wide meta-analysis in Japanese populations identifies novel variants at the TMC6-TMC8 and SIX3-SIX2 loci associated with HbA1c. PMID:29170429
Cartilage intermediate layer protein 1 (CILP1): A novel mediator of cardiac extracellular matrix remodelling. PMID:29167509
Genome analysis of the foxtail millet pathogen Sclerospora graminicola reveals the complex effector repertoire of graminicolous downy mildews. PMID:29166857
Profiling of proteins secreted in the bovine oviduct reveals diverse functions of this luminal microenvironment. PMID:29155854
Generational comparisons (F1 versus F3) of vinclozolin induced epigenetic transgenerational inheritance of sperm differential DNA methylation regions (epimutations) using MeDIP-Seq. PMID:29147574
BRACHYURY directs histone acetylation to target loci during mesoderm development. PMID:29141987
Sub-minute Phosphoregulation of Cell Cycle Systems during Plasmodium Gamete Formation. PMID:29141230
Subcellular analysis of pigeon hair cells implicates vesicular trafficking in cuticulosome formation and maintenance. PMID:29140244
Artificial selection for odor-guided behavior in Drosophila reveals changes in food consumption. PMID:29132294
Comprehensive analysis of gene expression patterns in Friedreich's ataxia fibroblasts by RNA sequencing reveals altered levels of protein synthesis factors and solute carriers. PMID:29125828
Profiling of Protein O-GlcNAcylation in Murine CD8+ Effector- and Memory-like T Cells. PMID:29125738
Temporally distinct transcriptional regulation of myocyte dedifferentiation and Myofiber growth during muscle regeneration. PMID:29121865
Lung epithelial response to cigarette smoke and modulation by the nicotinic alpha 7 receptor. PMID:29117258
Transcriptional correlates of proximal-distal identify and regeneration timing in axolotl limbs. PMID:29107037
Neuropilin-1 is a glial cell line-derived neurotrophic factor receptor in glioblastoma. PMID:29088765
TU-Tagging: A Method for Identifying Layer-Enriched Neuronal Genes in Developing Mouse Visual Cortex. PMID:29085897
Genome-wide analysis reveals differential selection involved with copy number variation in diverse Chinese Cattle. PMID:29085051
Integrated Proteomic and Transcriptomic Analysis Reveals Long Noncoding RNA HOX Transcript Antisense Intergenic RNA (HOTAIR) Promotes Hepatocellular Carcinoma Cell Proliferation by Regulating Opioid Growth Factor Receptor (OGFr). PMID:29079719
Epigenetics and adaptive phenotypic variation between habitats in an asexual snail. PMID:29074962
Riboproteomics: A versatile approach for the identification of host protein interaction network in plant pathogenic noncoding RNAs. PMID:29073276
Interferon regulated gene (IRG) expression-signature in a mouse model of chikungunya virus neurovirulence. PMID:29067635
Cytoplasmic cyclin D1 controls the migration and invasiveness of mantle lymphoma cells. PMID:29066743
Regulatory remodeling in the allo-tetraploid frog Xenopus laevis. PMID:29065907
Whole transcriptome analysis of human erythropoietic cells during ontogenesis suggests a role of VEGFA gene as modulator of fetal hemoglobin and pharmacogenomic biomarker of treatment response to hydroxyurea in β-type hemoglobinopathy patients. PMID:29061162
Comprehensive immune transcriptomic analysis in bladder cancer reveals subtype specific immune gene expression patterns of prognostic relevance. PMID:29050337
Isotope-coded protein label based quantitative proteomic analysis reveals significant up-regulation of apolipoprotein A1 and ovotransferrin in the myopic chick vitreous. PMID:28978931
Early Life Exposure to Low Levels of AHR Agonist PCB126 (3,3',4,4',5-Pentachlorobiphenyl) Reprograms Gene Expression in Adult Brain. PMID:28973690
Low-dose rapamycin extends lifespan in a mouse model of mtDNA depletion syndrome. PMID:28973153
The molecular characterization of porcine egg precursor cells. PMID:28969006
Adenovirus E1A TRRAP-targeting domain-mediated enhancement of MYC association with the NuA4 complex activates a panel of MYC target genes enriched for gene expression and ribosome biogenesis. PMID:28965007
Anti-mycobacterial activity correlates with altered DNA methylation pattern in immune cells from BCG-vaccinated subjects. PMID:28951586
Relating protein functional diversity to cell type number identifies genes that determine dynamic aspects of chromatin organisation as potential contributors to organismal complexity. PMID:28945800
Intestinal Epithelial and Intraepithelial T Cell Crosstalk Mediates a Dynamic Response to Infection. PMID:28942917
Transcriptomic and bioinformatics analysis of the early time-course of the response to prostaglandin F2 alpha in the bovine corpus luteum. PMID:28932774
Small-Molecule Screens: A Gateway to Cancer Therapeutic Agents with Case Studies of Food and Drug Administration-Approved Drugs. PMID:28931623
Atrazine induced epigenetic transgenerational inheritance of disease, lean phenotype and sperm epimutation pathology biomarkers. PMID:28931070
Comparative transcriptome analysis provides clues to molecular mechanisms underlying blue-green eggshell color in the Jinding duck (Anas platyrhynchos). PMID:28899357
SERPING1 mRNA overexpression in monocytes from HIV+ patients. PMID:28889214
Disease-stabilizing treatment based on all-trans retinoic acid and valproic acid in acute myeloid leukemia - identification of responders by gene expression profiling of pretreatment leukemic cells. PMID:28877686
Tumor cell senescence response produces aggressive variants. PMID:28845296
Auxin Response Factor Genes Repertoire in Mulberry: Identification, and Structural, Functional and Evolutionary Analyses. PMID:28841197
Pervasive coexpression of spatially proximal genes is buffered at the protein level. PMID:28835372
Treating the placenta to prevent adverse effects of gestational hypoxia on fetal brain development. PMID:28831049
Excess Translation of Epigenetic Regulators Contributes to Fragile X Syndrome and Is Alleviated by Brd4 Inhibition. PMID:28823556
Gene structure and comparative and phylogenetic analyses of Catla catla CYP1A full-length cDNA and its responsiveness to benzo(a)pyrene and copper sulphate at early developmental stages. PMID:28822029
Comprehensive comparison of neonate and adult human platelet transcriptomes. PMID:28813466
A plant effector-triggered immunity signaling sector is inhibited by pattern-triggered immunity. PMID:28811287
RNA-Seq using bulked recombinant inbred line populations uncovers the importance of brassinosteroid for seed longevity after priming treatments. PMID:28808238
Draft de novo transcriptome assembly and proteome characterization of the electric lobe of Tetronarce californica: a molecular tool for the study of cholinergic neurotransmission in the electric organ. PMID:28806931
Silencing of Repetitive DNA Is Controlled by a Member of an Unusual Caenorhabditis elegans Gene Family. PMID:28801529
β-Catenin Knockdown Affects Mitochondrial Biogenesis and Lipid Metabolism in Breast Cancer Cells. PMID:28798698
Mechanical instability and titanium particles induce similar transcriptomic changes in a rat model for periprosthetic osteolysis and aseptic loosening. PMID:28795083
Identification of the SOX2 Interactome by BioID Reveals EP300 as a Mediator of SOX2-dependent Squamous Differentiation and Lung Squamous Cell Carcinoma Growth. PMID:28794006
In vivo Host-Pathogen Interaction as Revealed by Global Proteomic Profiling of Zebrafish Larvae. PMID:28791256
Use of Proteomics To Investigate Kidney Function Decline over 5 Years. PMID:28784837
Systematic Selection of Reference Genes for the Normalization of Circulating RNA Transcripts in Pregnant Women Based on RNA-Seq Data. PMID:28777335
High-Coverage Whole-Exome Sequencing Identifies Candidate Genes for Suicide in Victims with Major Depressive Disorder. PMID:28769055
Quantitative Proteomic Analysis of Optimal Cutting Temperature (OCT) Embedded Core-Needle Biopsy of Lung Cancer. PMID:28752479
Proteomic analysis of human follicular fluid associated with successful in vitro fertilization. PMID:28750635
RNA sequencing reveals resistance of TLR4 ligand-activated microglial cells to inflammation mediated by the selective jumonji H3K27 demethylase inhibitor. PMID:28747667
Porcine familial adenomatous polyposis model enables systematic analysis of early events in adenoma progression. PMID:28747659
Antarctic Moss Multiprotein Bridging Factor 1c Overexpression in Arabidopsis Resulted in Enhanced Tolerance to Salt Stress. PMID:28744295
MYC2 Orchestrates a Hierarchical Transcriptional Cascade That Regulates Jasmonate-Mediated Plant Immunity in Tomato. PMID:28733419
NoGOA: predicting noisy GO annotations using evidences and sparse representation. PMID:28732468
Proteomic profiling of early degenerative retina of RCS rats. PMID:28730077
Mutation intolerant genes and targets of FMRP are enriched for nonsynonymous alleles in schizophrenia. PMID:28719003
PLAG1 deficiency impairs spermatogenesis and sperm motility in mice. PMID:28706261
The miR-15 family reinforces the transition from proliferation to differentiation in pre-B cells. PMID:28705801
Elucidating Protein-DNA Interactions in Human Alphoid Chromatin via Hybridization Capture and Mass Spectrometry. PMID:28704058
Genome wide re-sequencing of newly developed Rice Lines from common wild rice (Oryza rufipogon Griff.) for the identification of NBS-LRR genes. PMID:28700714
TRPM7 senses oxidative stress to release Zn2+ from unique intracellular vesicles. PMID:28696294
Tsc2 disruption in mesenchymal progenitors results in tumors with vascular anomalies overexpressing Lgals3. PMID:28695825
Key Components of Different Plant Defense Pathways Are Dispensable for Powdery Mildew Resistance of the Arabidopsis mlo2 mlo6 mlo12 Triple Mutant. PMID:28674541
Large-Scale Analysis of Breast Cancer-Related Conformational Changes in Proteins Using SILAC-SPROX. PMID:28673085
In-Depth Proteomic Analysis of the Hippocampus in a Rat Model after Cerebral Ischaemic Injury and Repair by Danhong Injection (DHI). PMID:28672812
Quantitative Proteomics Analysis of Plasmodium vivax Induced Alterations in Human Serum during the Acute and Convalescent Phases of Infection. PMID:28667326
Identification and Characterization of miRNA Transcriptome in Asiatic Cotton (Gossypium arboreum) Using High Throughput Sequencing. PMID:28663752
METTL21B Is a Novel Human Lysine Methyltransferase of Translation Elongation Factor 1A: Discovery by CRISPR/Cas9 Knockout. PMID:28663172
Transcriptomic Profiling of Posterior Polymorphous Corneal Dystrophy. PMID:28654985
Effect of praziquantel on the differential expression of mouse hepatic genes and parasite ATP binding cassette transporter gene family members during Schistosoma mansoni infection. PMID:28650976
The evening complex coordinates environmental and endogenous signals in Arabidopsis. PMID:28650433
Characterizing the reproductive transcriptomic correlates of acute dehydration in males in the desert-adapted rodent, Peromyscus eremicus. PMID:28645248
Ageing and hypoxia cause protein aggregation in mitochondria. PMID:28644434
High-confidence assessment of functional impact of human mitochondrial non-synonymous genome variations by APOGEE. PMID:28640805
The islet-resident macrophage is in an inflammatory state and senses microbial products in blood. PMID:28630088
UHRF1 is required for basal stem cell proliferation in response to airway injury. PMID:28626588
Effect of Sweetened Dried Cranberry Consumption on Urinary Proteome and Fecal Microbiome in Healthy Human Subjects. PMID:28618237
Time-Dependent, HIV-Tat-Induced Perturbation of Human Neurons In Vitro: Towards a Model for the Molecular Pathology of HIV-Associated Neurocognitive Disorders. PMID:28611588
Gene Expression Profiling of Chemokines and Their Receptors in Low and High Grade Astrocytoma. PMID:28610419
Genome-wide profiling of S/MAR-based replicon contact sites. PMID:28609784
Low-coverage resequencing detects meiotic recombination pattern and features in tomato RILs. PMID:28605512
A mutant O-GlcNAcase enriches Drosophila developmental regulators. PMID:28604694
TCR Signal Strength Regulates Akt Substrate Specificity To Induce Alternate Murine Th and T Regulatory Cell Differentiation Programs. PMID:28600288
SPARC overexpression suppresses radiation-induced HSP27 and induces the collapse of mitochondrial Δψ in neuroblastoma cells. PMID:28599461
Ocoxin oral solution® as a complement to irinotecan chemotherapy in the metastatic progression of colorectal cancer to the liver. PMID:28599406
Genomewide Mutational Diversity in Escherichia coli Population Evolving in Prolonged Stationary Phase. PMID:28567442
Gene Set Enrichment Analyses: lessons learned from the heart failure phenotype. PMID:28559929
Identification of oral cancer related candidate genes by integrating protein-protein interactions, gene ontology, pathway analysis and immunohistochemistry. PMID:28559546
Early transcriptome responses of the bovine midcycle corpus luteum to prostaglandin F2α includes cytokine signaling. PMID:28549990
ChiPPI: a novel method for mapping chimeric protein-protein interactions uncovers selection principles of protein fusion events in cancer. PMID:28549153
Comparison between chaotropic and detergent-based sample preparation workflow in tendon for mass spectrometry analysis. PMID:28547889
LPS-induced systemic inflammation reveals an immunomodulatory role for the prion protein at the blood-brain interface. PMID:28532450
Proteomic analysis of cerebrospinal fluid from children with central nervous system tumors identifies candidate proteins relating to tumor metastatic spread. PMID:28526811
Role of carbonic anhydrases in skin wound healing. PMID:28524177
Early social learning triggers neurogenomic expression changes in a swordtail fish. PMID:28515207
Identification of preoptic sleep neurons using retrograde labelling and gene profiling. PMID:28514446
Proteoforms in Peripheral Blood Mononuclear Cells as Novel Rejection Biomarkers in Liver Transplant Recipients. PMID:28510335
In vivo mapping of tissue- and subcellular-specific proteomes in Caenorhabditis elegans. PMID:28508060
Proteomic responses to elevated ocean temperature in ovaries of the ascidian Ciona intestinalis. PMID:28500033
Proteomics analysis of pleomorphic adenoma of the human parotid gland. PMID:28497265
Characterization of Copy Number Variation's Potential Role in Marek's Disease. PMID:28486430
Nucleosome eviction along with H3K9ac deposition enhances Sox2 binding during human neuroectodermal commitment. PMID:28475175
Mutant IDH1 regulates the tumor-associated immune system in gliomas. PMID:28465358
Mercury-induced epigenetic transgenerational inheritance of abnormal neurobehavior is correlated with sperm epimutations in zebrafish. PMID:28464002
Single-cell topological RNA-seq analysis reveals insights into cellular differentiation and development. PMID:28459448
The ubiquitin ligase LIN41/TRIM71 targets p53 to antagonize cell death and differentiation pathways during stem cell differentiation. PMID:28430184
Decreased Levels of Foldase and Chaperone Proteins Are Associated with an Early-Onset Amyotrophic Lateral Sclerosis. PMID:28428745
Screening effective differential expression genes for hepatic carcinoma with metastasis in the peripheral blood mononuclear cells by RNA-seq. PMID:28427195
Robust in-silico identification of cancer cell lines based on next generation sequencing. PMID:28415721
Highly accessible AU-rich regions in 3' untranslated regions are hotspots for binding of regulatory factors. PMID:28410363
Longitudinal peripheral blood transcriptional analysis of a patient with severe Ebola virus disease. PMID:28404864
Quantitative Proteomic Analysis of Mosquito C6/36 Cells Reveals Host Proteins Involved in Zika Virus Infection. PMID:28404849
Biotagging of Specific Cell Populations in Zebrafish Reveals Gene Regulatory Logic Encoded in the Nuclear Transcriptome. PMID:28402863
The prominent proteins expressed in healthy gingiva: a pilot exploratory tissue proteomics study. PMID:28382581
Myt1l safeguards neuronal identity by actively repressing many non-neuronal fates. PMID:28379941
Fuento: functional enrichment for bioinformatics. PMID:28379299
Ultra-High Mass Resolution MALDI Imaging Mass Spectrometry of Proteins and Metabolites in a Mouse Model of Glioblastoma. PMID:28377615
A small-molecule screen reveals that HSP90β promotes the conversion of induced pluripotent stem cell-derived endoderm to a hepatic fate and regulates HNF4A turnover. PMID:28360131
Transcriptome Analysis of Hypothalamic Gene Expression during Daily Torpor in Djungarian Hamsters (Phodopus sungorus). PMID:28348515
Proteomics and integrative omic approaches for understanding host-pathogen interactions and infectious diseases. PMID:28348067
Comparative Sperm Proteomics in Mouse Species with Divergent Mating Systems. PMID:28333336
Azacitidine Mitigates Graft-versus-Host Disease via Differential Effects on the Proliferation of T Effectors and Natural Regulatory T Cells In Vivo. PMID:28330901
Identification and characterization of a missense mutation in the O-linked β-N-acetylglucosamine (O-GlcNAc) transferase gene that segregates with X-linked intellectual disability. PMID:28302723
Network reconstruction of the mouse secretory pathway applied on CHO cell transcriptome data. PMID:28298216
Extensive Copy Number Variation in Fermentation-Related Genes Among Saccharomyces cerevisiae Wine Strains. PMID:28292787
Chromatin landscapes and genetic risk for juvenile idiopathic arthritis. PMID:28288683
Identifying protein kinase-specific effectors of the osmostress response in yeast. PMID:28270554
Pre-Exposure Gene Expression in Baboons with and without Pancytopenia after Radiation Exposure. PMID:28257102
Prediction of GCRV virus-host protein interactome based on structural motif-domain interactions. PMID:28253857
The microstructure and micromechanics of the tendon-bone insertion. PMID:28250445
TFAP2 paralogs regulate melanocyte differentiation in parallel with MITF. PMID:28249010
Comparing Simplification Strategies for the Skeletal Muscle Proteome. PMID:28248220
Integrating Gene Expression with Summary Association Statistics to Identify Genes Associated with 30 Complex Traits. PMID:28238358
Plasma Exosome Profiling of Cancer Patients by a Next Generation Systems Biology Approach. PMID:28218293
Using predictive specificity to determine when gene set analysis is biologically meaningful. PMID:28204549
A novel hypothesis-unbiased method for Gene Ontology enrichment based on transcriptome data. PMID:28199395
Sm-p80-based schistosomiasis vaccine mediated epistatic interactions identified potential immune signatures for vaccine efficacy in mice and baboons. PMID:28192534
Serine ADP-Ribosylation Depends on HPF1. PMID:28190768
Transcriptome Profiling of In-Vivo Produced Bovine Pre-implantation Embryos Using Two-color Microarray Platform. PMID:28190024
Widespread signatures of positive selection in common risk alleles associated to autism spectrum disorder. PMID:28187187
Transcriptional regulation of male-sterility in 7B-1 male-sterile tomato mutant. PMID:28178307
Systematic Profiling of Short Tandem Repeats in the Cattle Genome. PMID:28172841
Estrogen receptor α wields treatment-specific enhancers between morphologically similar endometrial tumors. PMID:28167798
Comparative Transcriptomics of Malaria Mosquito Testes: Function, Evolution, and Linkage. PMID:28159865
Cardiac Med1 deletion promotes early lethality, cardiac remodeling, and transcriptional reprogramming. PMID:28159809
Deep-proteome mapping of WM-266-4 human metastatic melanoma cells: From oncogenic addiction to druggable targets. PMID:28158294
Identification of calgranulin B interacting proteins and network analysis in gastrointestinal cancer cells. PMID:28152021
Protein Bioinformatics Databases and Resources. PMID:28150231
Differential DNA Methylation Regions in Adult Human Sperm following Adolescent Chemotherapy: Potential for Epigenetic Inheritance. PMID:28146567
Identification of novel follicular dendritic cell sarcoma markers, FDCSP and SRGN, by whole transcriptome sequencing. PMID:28145886
Using the shared genetics of dystonia and ataxia to unravel their pathogenesis. PMID:28143763
Transcriptomic Modification in the Cerebral Cortex following Noninvasive Brain Stimulation: RNA-Sequencing Approach. PMID:28119786
Tissue resolved, gene structure refined equine transcriptome. PMID:28107812
Identification of shared and unique gene families associated with oral clefts. PMID:28106045
A compendium of human genes regulating feeding behavior and body weight, its functional characterization and identification of GWAS genes involved in brain-specific PPI network. PMID:28105929
The gene-expression profile of renal medulla in ISIAH rats with inherited stress-induced arterial hypertension. PMID:28105926
Molecular determinants of the adrenal gland functioning related to stress-sensitive hypertension in ISIAH rats. PMID:28105924
Dynamics of tRNA fragments and their targets in aging mammalian brain. PMID:28105302
Quantitative iTRAQ-based proteomic analysis of rice grains to assess high night temperature stress. PMID:28101936
Conserved gene expression in sperm reservoirs between birds and mammals in response to mating. PMID:28100167
Comparative proteomics of paired vocal fold and oral mucosa fibroblasts. PMID:28099887
MerR and ChrR mediate blue light induced photo-oxidative stress response at the transcriptional level in Vibrio cholerae. PMID:28098242
Association of Body Mass Index with DNA Methylation and Gene Expression in Blood Cells and Relations to Cardiometabolic Disease: A Mendelian Randomization Approach. PMID:28095459
Integrated proteomic and N-glycoproteomic analyses of doxorubicin sensitive and resistant ovarian cancer cells reveal glycoprotein alteration in protein abundance and glycosylation. PMID:28077793
Extracellular MicroRNA Signature of Human Helper T Cell Subsets in Health and Autoimmunity. PMID:28077577
Gene co-expression analysis for functional classification and gene-disease predictions. PMID:28077403
De novo assembly, annotation, and characterization of the whole brain transcriptome of male and female Syrian hamsters. PMID:28071753
IL-1β-induced modulation of gene expression profile in human dermal fibroblasts: the effects of Thai herbal Sahatsatara formula, piperine and gallic acid possessing antioxidant properties. PMID:28068976
Therapeutic Targeting of MLL Degradation Pathways in MLL-Rearranged Leukemia. PMID:28065413
LPS-induced modules of co-expressed genes in equine peripheral blood mononuclear cells. PMID:28056766
Species-Specific Responses of Juvenile Rockfish to Elevated pCO2: From Behavior to Genomics. PMID:28056071
Transcriptome Analysis Identifies Key Metabolic Changes in the Hooded Seal (Cystophora cristata) Brain in Response to Hypoxia and Reoxygenation. PMID:28046118
Normalization of Hepatic Homeostasis in the Npc1nmf164 Mouse Model of Niemann-Pick Type C Disease Treated with the Histone Deacetylase Inhibitor Vorinostat. PMID:28031458
Network Analysis-Based Approach for Exploring the Potential Diagnostic Biomarkers of Acute Myocardial Infarction. PMID:28018242
The C-Terminal SynMuv/DdDUF926 Domain Regulates the Function of the N-Terminal Domain of DdNKAP. PMID:27997579
The genome of the Gulf pipefish enables understanding of evolutionary innovations. PMID:27993155
Identifying ultrasensitive HGF dose-response functions in a 3D mammalian system for synthetic morphogenesis. PMID:27982133
Mobile-phone radiation-induced perturbation of gene-expression profiling, redox equilibrium and sporadic-apoptosis control in the ovary of Drosophila melanogaster. PMID:27960592
Gene Co-Expression Network Analysis Unraveling Transcriptional Regulation of High-Altitude Adaptation of Tibetan Pig. PMID:27936142
Datasets for the validation of the "in vivo" siRNA-silencing of CD40 and for the detection of new markers of atherosclerosis progression in ApoE-deficient mice. PMID:27924297
Evolutionary and Functional Features of Copy Number Variation in the Cattle Genome. PMID:27920798
Nitric Oxide Responsive Heavy Metal-Associated Gene AtHMAD1 Contributes to Development and Disease Resistance in Arabidopsis thaliana. PMID:27917181
The Hippo Pathway Kinases LATS1/2 Suppress Cancer Immunity. PMID:27912060
PANTHER version 11: expanded annotation data from Gene Ontology and Reactome pathways, and data analysis tool enhancements. PMID:27899595
TP53 mutations, expression and interaction networks in human cancers. PMID:27880943
Circulating microRNA levels predict residual beta cell function and glycaemic control in children with type 1 diabetes mellitus. PMID:27866223
A Platform for Designing Genome-Based Personalized Immunotherapy or Vaccine against Cancer. PMID:27832200
Primer on the Gene Ontology. PMID:27812933
Comparative Gene Expression Profiling of Primary and Metastatic Renal Cell Carcinoma Stem Cell-Like Cancer Cells. PMID:27812180
Ancient Out-of-Africa Mitochondrial DNA Variants Associate with Distinct Mitochondrial Gene Expression Patterns. PMID:27812116
Gene silencing pathways found in the green alga Volvox carteri reveal insights into evolution and origins of small RNA systems in plants. PMID:27806710
ATR maintains chromosomal integrity during postnatal cerebellar neurogenesis and is required for medulloblastoma formation. PMID:27803059
Application of rice microspore-preferred promoters to manipulate early pollen development in Arabidopsis: a heterologous system. PMID:27796586
ATM/G6PD-driven redox metabolism promotes FLT3 inhibitor resistance in acute myeloid leukemia. PMID:27791036
Differential expression analysis of the broiler tracheal proteins responsible for the immune response and muscle contraction induced by high concentration of ammonia using iTRAQ-coupled 2D LC-MS/MS. PMID:27761697
Human genome-wide RNAi screen reveals host factors required for enterovirus 71 replication. PMID:27748395
Gene Function Prediction Based on Developmental Transcriptomes of the Two Sexes in C. elegans. PMID:27732864
Detecting Sources of Transcriptional Heterogeneity in Large-Scale RNA-Seq Data Sets. PMID:27729424
Defining Trends in Global Gene Expression in Arabian Horses with Cerebellar Abiotrophy. PMID:27709457
Meta-analysis of gene expression and integrin-associated signaling pathways in papillary renal cell carcinoma subtypes. PMID:27705936
Depot specific differences in the adipogenic potential of precursors are mediated by collagenous extracellular matrix and Flotillin 2 dependent signaling. PMID:27689006
REV-ERBα influences the stability and nuclear localization of the glucocorticoid receptor. PMID:27686098
Transcriptional profile of SH-SY5Y human neuroblastoma cells transfected by Toxoplasma rhoptry protein 16. PMID:27666388
Opposing impacts on healthspan and longevity by limiting dietary selenium in telomere dysfunctional mice. PMID:27653523
Comparative protein profiling of B16 mouse melanoma cells susceptible and non-susceptible to alphavirus infection: Effect of the tumor microenvironment. PMID:27636533
Exploiting Gene Expression Kinetics in Conventional Radiotherapy, Hyperfractionation, and Hypofractionation for Targeted Therapy. PMID:27619247
Quantitative Proteomic Analysis of Escherichia coli Heat-Labile Toxin B Subunit (LTB) with Enterovirus 71 (EV71) Subunit VP1. PMID:27618897
RNA-seq analysis of the transcriptional response to blue and red light in the extremophilic red alga, Cyanidioschyzon merolae. PMID:27614431
Novel Aquaporin Regulatory Mechanisms Revealed by Interactomics. PMID:27609422
Sublethal salinity stress contributes to habitat limitation in an endangered estuarine fish. PMID:27606005
Distinct microenvironmental cues stimulate divergent TLR4-mediated signaling pathways in macrophages. PMID:27577261
A novel 3D human glioblastoma cell culture system for modeling drug and radiation responses. PMID:27576873
Molecular Principles of Gene Fusion Mediated Rewiring of Protein Interaction Networks in Cancer. PMID:27540857
An integrative transcriptomics approach identifies miR-503 as a candidate master regulator of the estrogen response in MCF-7 breast cancer cells. PMID:27539783
REST is a hypoxia-responsive transcriptional repressor. PMID:27531581
Supplements of vitamins B9 and B12 affect hepatic and mammary gland gene expression profiles in lactating dairy cows. PMID:27526683
Mammalian PNLDC1 is a novel poly(A) specific exonuclease with discrete expression during early development. PMID:27515512
Glucose or Altered Ceramide Biosynthesis Mediate Oxygen Deprivation Sensitivity Through Novel Pathways Revealed by Transcriptome Analysis in Caenorhabditis elegans. PMID:27507791
When the brain goes diving: transcriptome analysis reveals a reduced aerobic energy metabolism and increased stress proteins in the seal brain. PMID:27507242
Genome-wide analysis reveals conserved transcriptional responses downstream of resting potential change in Xenopus embryos, axolotl regeneration, and human mesenchymal cell differentiation. PMID:27499876
Integrative exploration of genomic profiles for triple negative breast cancer identifies potential drug targets. PMID:27472710
Function Over Form: Modeling Groups of Inherited Neurological Conditions in Zebrafish. PMID:27458342
Identification of SNP and SSR Markers in Finger Millet Using Next Generation Sequencing Technologies. PMID:27454301
Cortisol-treated zebrafish embryos develop into pro-inflammatory adults with aberrant immune gene regulation. PMID:27444789
Identifying Aspects of the Post-Transcriptional Program Governing the Proteome of the Green Alga Micromonas pusilla. PMID:27434306
Interaction of the Chromatin Remodeling Protein hINO80 with DNA. PMID:27428271
Analyses of Compact Trichinella Kinomes Reveal a MOS-Like Protein Kinase with a Unique N-Terminal Domain. PMID:27412987
Research Resource: A Reference Transcriptome for Constitutive Androstane Receptor and Pregnane X Receptor Xenobiotic Signaling. PMID:27409825
Cellular and molecular phenotypes depending upon the RNA repair system RtcAB of Escherichia coli. PMID:27402162
Whole-Genome Sequencing of Native Sheep Provides Insights into Rapid Adaptations to Extreme Environments. PMID:27401233
Uncovering the liver's role in immunity through RNA co-expression networks. PMID:27401171
Anti-Müllerian Hormone Signaling Regulates Epithelial Plasticity and Chemoresistance in Lung Cancer. PMID:27396341
Identification of learning-induced changes in protein networks in the hippocampi of a mouse model of Alzheimer's disease. PMID:27378549
Temporal Regulation of the Bacillus subtilis Acetylome and Evidence for a Role of MreB Acetylation in Cell Wall Growth. PMID:27376153
Computational Identification of the Paralogs and Orthologs of Human Cytochrome P450 Superfamily and the Implication in Drug Discovery. PMID:27367670
Desmoglein 2 promotes vasculogenic mimicry in melanoma and is associated with poor clinical outcome. PMID:27340778
Proteomic analyses of brain tumor cell lines amidst the unfolded protein response. PMID:27323862
Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine. PMID:27322543
Identification of long non-coding RNAs involved in neuronal development and intellectual disability. PMID:27319317
The alternative splicing program of differentiated smooth muscle cells involves concerted non-productive splicing of post-transcriptional regulators. PMID:27317697
Genome-wide characterization of human L1 antisense promoter-driven transcripts. PMID:27301971
De novo assembly of a tadpole shrimp (Triops newberryi) transcriptome and preliminary differential gene expression analysis. PMID:27292122
Emergence and Evolution of Hominidae-Specific Coding and Noncoding Genomic Sequences. PMID:27289096
Identification of circulating microRNAs during the liver neoplastic process in a murine model of hereditary tyrosinemia type 1. PMID:27282650
Identification of RNA-binding Proteins in Macrophages by Interactome Capture. PMID:27281784
Transplantation of iPSC-derived TM cells rescues glaucoma phenotypes in vivo. PMID:27274060
Horizontal gene transfer events reshape the global landscape of arm race between viruses and homo sapiens. PMID:27270140
Identification of the MicroRNA Repertoire in TLR-Ligand Challenged Bubaline PBMCs as a Model of Bacterial and Viral Infection. PMID:27257788
The proteome of the infectious bronchitis virus Beau-R virion. PMID:27257648
Sequence/structural analysis of xylem proteome emphasizes pathogenesis-related proteins, chitinases and β-1, 3-glucanases as key players in grapevine defense against Xylella fastidiosa. PMID:27257535
Minor intron splicing is regulated by FUS and affected by ALS-associated FUS mutants. PMID:27252488
Serum-derived exosomes from non-viremic animals previously exposed to the porcine respiratory and reproductive virus contain antigenic viral proteins. PMID:27246926
Heterologous Overexpression of Poplar SnRK2 Genes Enhanced Salt Stress Tolerance in Arabidopsis thaliana. PMID:27242819
Hyperosmotic stress memory in Arabidopsis is mediated by distinct epigenetically labile sites in the genome and is restricted in the male germline by DNA glycosylase activity. PMID:27242129
Proteomic Study of Entamoeba histolytica Trophozoites, Cysts, and Cyst-Like Structures. PMID:27228164
Transcriptome Analysis Reveals a Signature Profile for Tick-Borne Flavivirus Persistence in HEK 293T Cells. PMID:27222466
Genome-scale RNA interference screen identifies antizyme 1 (OAZ1) as a target for improvement of recombinant protein production in mammalian cells. PMID:27215166
Genome-wide analysis of the transcriptional response to porcine reproductive and respiratory syndrome virus infection at the maternal/fetal interface and in the fetus. PMID:27207143
Proteomic analysis of stromal proteins in different stages of colorectal cancer establishes Tenascin-C as a stromal biomarker for colorectal cancer metastasis. PMID:27191989
Identification of brain-enriched proteins in the cerebrospinal fluid proteome by LC-MS/MS profiling and mining of the Human Protein Atlas. PMID:27186164
Systems-level analysis of human aging genes shed new light on mechanisms of aging. PMID:27179790
Identification of novel direct targets of Drosophila Sine oculis and Eyes absent by integration of genome-wide data sets. PMID:27178668
The cis-acting replication element of the Hepatitis C virus genome recruits host factors that influence viral replication and translation. PMID:27165399
Building a glaucoma interaction network using a text mining approach. PMID:27152122
Neuronal cell lines as model dorsal root ganglion neurons: A transcriptomic comparison. PMID:27130590
Network-driven plasma proteomics expose molecular changes in the Alzheimer's brain. PMID:27112350
Unraveling molecular effects of ADAR1 overexpression in HEK293T cells by label-free quantitative proteomics. PMID:27104882
g:Profiler-a web server for functional interpretation of gene lists (2016 update). PMID:27098042
Global proteome profiling of dental cementum under experimentally-induced apposition. PMID:27095596
Ebola virus encodes a miR-155 analog to regulate importin-α5 expression. PMID:27094387
Screening of whole genome sequences identified high-impact variants for stallion fertility. PMID:27079378
Tissue- and stage-specific Wnt target gene expression is controlled subsequent to β-catenin recruitment to cis-regulatory modules. PMID:27068107
Unbiased identification of substrates of protein tyrosine phosphatase ptp-3 in C. elegans. PMID:27067626
Genome-wide DNA hydroxymethylation identifies potassium channels in the nucleus accumbens as discriminators of methamphetamine addiction and abstinence. PMID:27046646
Mechanistic evaluation of primary human hepatocyte culture using global proteomic analysis reveals a selective dedifferentiation profile. PMID:27039104
S-nitrosation of proteins relevant to Alzheimer's disease during early stages of neurodegeneration. PMID:27035958
Spatiotemporal Expression and Molecular Characterization of miR-344b and miR-344c in the Developing Mouse Brain. PMID:27034842
Evaluation of the mirn23a Cluster through an iTRAQ-based Quantitative Proteomic Approach. PMID:27028342
Characterization of site-specific glycosylation of secreted proteins associated with multi-drug resistance of gastric cancer. PMID:27015365
In-depth analysis of secretome and N-glycosecretome of human hepatocellular carcinoma metastatic cell lines shed light on metastasis correlated proteins. PMID:27014972
Integrated analysis of long non-coding RNAs in human colorectal cancer. PMID:27004403
Identification and Analysis of Novel Viral and Host Dysregulated MicroRNAs in Variant Pseudorabies Virus-Infected PK15 Cells. PMID:26998839
The acetyllysine reader BRD3R promotes human nuclear reprogramming and regulates mitosis. PMID:26947130
A bead-based cleavage method for large-scale identification of protease substrates. PMID:26935269
Major Transcriptome Changes Accompany the Growth of Pseudomonas aeruginosa in Blood from Patients with Severe Thermal Injuries. PMID:26933952
Premature termination codons in modern human genomes. PMID:26932450
Cells release subpopulations of exosomes with distinct molecular and biological properties. PMID:26931825
Key Immune Events of the Pathomechanisms of Early Cardioembolic Stroke: Multi-Database Mining and Systems Biology Approach. PMID:26927091
Genetic overlap between multiple sclerosis and several cardiovascular disease risk factors. PMID:26920376
Proteomic identification of fat-browning markers in cultured white adipocytes treated with curcumin. PMID:26915100
Genetic Risk Score Modelling for Disease Progression in New-Onset Type 1 Diabetes Patients: Increased Genetic Load of Islet-Expressed and Cytokine-Regulated Candidate Genes Predicts Poorer Glycemic Control. PMID:26904692
Bivalve-specific gene expansion in the pearl oyster genome: implications of adaptation to a sessile lifestyle. PMID:26900483
Ensembl comparative genomics resources. PMID:26896847
MiRNA-128 regulates the proliferation and neurogenesis of neural precursors by targeting PCM1 in the developing cortex. PMID:26883496
Whole genome resequencing of the human parasite Schistosoma mansoni reveals population history and effects of selection. PMID:26879532
Transcription-associated processes cause DNA double-strand breaks and translocations in neural stem/progenitor cells. PMID:26873106
Comparative analysis of Cu (I)-catalyzed alkyne-azide cycloaddition (CuAAC) and strain-promoted alkyne-azide cycloaddition (SPAAC) in O-GlcNAc proteomics. PMID:26853435
An integrated in silico approach for functional and structural impact of non- synonymous SNPs in the MYH1 gene in Jeju Native Pigs. PMID:26847462
Pet-1 Switches Transcriptional Targets Postnatally to Regulate Maturation of Serotonin Neuron Excitability. PMID:26843655
Reconstruction of the insulin-like signalling pathway of Haemonchus contortus. PMID:26842675
Anatomical heterogeneity of tendon: Fascicular and interfascicular tendon compartments have distinct proteomic composition. PMID:26842662
Defining the proteome of human iris, ciliary body, retinal pigment epithelium, and choroid. PMID:26834087
Interaction network of tobacco etch potyvirus NIa protein with the host proteome during infection. PMID:26830344
Genome-wide identification of copy number variation using high-density single-nucleotide polymorphism array in Japanese Black cattle. PMID:26809925
Quantitative phosphoproteomics reveals genistein as a modulator of cell cycle and DNA damage response pathways in triple-negative breast cancer cells. PMID:26783066
Comprehensive Proteomic Analysis of Mesenchymal Stem Cell Exosomes Reveals Modulation of Angiogenesis via Nuclear Factor-KappaB Signaling. PMID:26782178
Viral infection causes a shift in the self peptide repertoire presented by human MHC class I molecules. PMID:26768311
Sampling From the Proteome to the Human Leukocyte Antigen-DR (HLA-DR) Ligandome Proceeds Via High Specificity. PMID:26764012
Repurposing L-Menthol for Systems Medicine and Cancer Therapeutics? L-Menthol Induces Apoptosis through Caspase 10 and by Suppressing HSP90. PMID:26760959
Slowed aging during reproductive dormancy is reflected in genome-wide transcriptome changes in Drosophila melanogaster. PMID:26758761
Identification and preliminary characterization of chemosensory perception-associated proteins in the melon fly Bactrocera cucurbitae using RNA-seq. PMID:26752702
Environmental Correlation Analysis for Genes Associated with Protection against Malaria. PMID:26744416
Exome arrays capture polygenic rare variant contributions to schizophrenia. PMID:26740555
Expression of microRNAs in Horse Plasma and Their Characteristic Nucleotide Composition. PMID:26731407
Proteomic Characterization of Exosomes from HIV-1-Infected Cells. PMID:26714721
LymPHOS 2.0: an update of a phosphosite database of primary human T cells. PMID:26708986
Biomarker discovery in mass spectrometry-based urinary proteomics. PMID:26703953
The proteomic dataset for bone marrow derived human mesenchymal stromal cells: Effect of in vitro passaging. PMID:26702413
Integrative computational in-depth analysis of dysregulated miRNA-mRNA interactions in drug-resistant pediatric acute lymphoblastic leukemia cells: an attempt to obtain new potential gene-miRNA pathways involved in response to treatment. PMID:26700663
Leveraging global gene expression patterns to predict expression of unmeasured genes. PMID:26666289
Deep sequencing of Danish Holstein dairy cattle for variant detection and insight into potential loss-of-function variants in protein coding genes. PMID:26645365
The Haemonchus contortus kinome--a resource for fundamental molecular investigations and drug discovery. PMID:26644012
Global Profiling of Huntingtin-associated protein E (HYPE)-Mediated AMPylation through a Chemical Proteomic Approach. PMID:26604261
Osteoblast-released Matrix Vesicles, Regulation of Activity and Composition by Sulfated and Non-sulfated Glycosaminoglycans. PMID:26598647
O-Linked β-N-acetylglucosamine (O-GlcNAc) Acts as a Glucose Sensor to Epigenetically Regulate the Insulin Gene in Pancreatic Beta Cells. PMID:26598517
The anatomical distribution of genetic associations. PMID:26586807
Dual transcriptome sequencing reveals resistance of TLR4 ligand-activated bone marrow-derived macrophages to inflammation mediated by the BET inhibitor JQ1. PMID:26582142
PANTHER version 10: expanded protein families and functions, and analysis tools. PMID:26578592
Comparative Proteome Analysis of hAT-MSCs Isolated from Chronic Renal Failure Patients with Differences in Their Bone Turnover Status. PMID:26575497
Expression Profiling of Human Schlemm's Canal Endothelial Cells From Eyes With and Without Glaucoma. PMID:26567786
Shifts in rDNA levels act as a genome buffer promoting chromosome homeostasis. PMID:26566866
Conserved Molecular Underpinnings and Characterization of a Role for Caveolin-1 in the Tumor Microenvironment of Mature T-Cell Lymphomas. PMID:26566034
Cdk5 Regulates Activity-Dependent Gene Expression and Dendrite Development. PMID:26558783
Metformin inhibits hepatocellular glucose, lipid and cholesterol biosynthetic pathways by transcriptionally suppressing steroid receptor coactivator 2 (SRC-2). PMID:26548416
Characterization of the Saccharomyces cerevisiae ATP-Interactome using the iTRAQ-SPROX Technique. PMID:26530046
The RNA Splicing Response to DNA Damage. PMID:26529031
Olfactory bulb proteome dynamics during the progression of sporadic Alzheimer's disease: identification of common and distinct olfactory targets across Alzheimer-related co-pathologies. PMID:26517091
Mesenchymal Stem Cells Exhibit Regulated Exocytosis in Response to Chemerin and IGF. PMID:26513261
Cell-Specific mRNA Profiling of the Caenorhabditis elegans Somatic Gonadal Precursor Cells Identifies Suites of Sex-Biased and Gonad-Enriched Transcripts. PMID:26497144
Normal and Cystic Fibrosis Human Bronchial Epithelial Cells Infected with Pseudomonas aeruginosa Exhibit Distinct Gene Activation Patterns. PMID:26485688
Systems Biology for Smart Crops and Agricultural Innovation: Filling the Gaps between Genotype and Phenotype for Complex Traits Linked with Robust Agricultural Productivity and Sustainability. PMID:26484978
Single-Cell Expression Profiling Reveals a Dynamic State of Cardiac Precursor Cells in the Early Mouse Embryo. PMID:26469858
The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. PMID:26464438
Dynamics in Transcriptomics: Advancements in RNA-seq Time Course and Downstream Analysis. PMID:26430493
Time-Resolved Proteomic Visualization of Dendrimer Cellular Entry and Trafficking. PMID:26425924
Comparative proteomics reveals human pluripotent stem cell-derived limbal epithelial stem cells are similar to native ocular surface epithelial cells. PMID:26423138
The decrease in histone methyltransferase EZH2 in response to fluid shear stress alters endothelial gene expression and promotes quiescence. PMID:26416763
Short interspersed DNA elements and miRNAs: a novel hidden gene regulation layer in zebrafish? PMID:26363800
Proteomic analysis of HIV-1 Gag interacting partners using proximity-dependent biotinylation. PMID:26362536
Maternal SIN3A regulates reprogramming of gene expression during mouse preimplantation development. PMID:26353893
Integrative analysis of multi-omics data for identifying multi-markers for diagnosing pancreatic cancer. PMID:26328610
Blood-based lung cancer biomarkers identified through proteomic discovery in cancer tissues, cell lines and conditioned medium. PMID:26279647
Evaluating the Hypoxia Response of Ruffe and Flounder Gills by a Combined Proteome and Transcriptome Approach. PMID:26273839
Resistance to Inhibitors of Cholinesterase 3 (Ric-3) Expression Promotes Selective Protein Associations with the Human α7-Nicotinic Acetylcholine Receptor Interactome. PMID:26258666
ElemeNT: a computational tool for detecting core promoter elements. PMID:26226151
Transcriptome Profiling of Developing Murine Lens Through RNA Sequencing. PMID:26225632
The Esg Gene Is Involved in Nicotine Sensitivity in Drosophila melanogaster. PMID:26222315
Data for a comprehensive map and functional annotation of the human cerebrospinal fluid proteome. PMID:26217727
Whole transcriptome analysis reveals a role for OGG1-initiated DNA repair signaling in airway remodeling. PMID:26187872
Altering TET dioxygenase levels within physiological range affects DNA methylation dynamics of HEK293 cells. PMID:26186463
Heterogeneous susceptibility for uraemic media calcification and concomitant inflammation within the arterial tree. PMID:26185049
Understanding Xeroderma Pigmentosum Complementation Groups Using Gene Expression Profiling after UV-Light Exposure. PMID:26184184
Genome-Wide Profiling of Histone Modifications (H3K9me2 and H4K12ac) and Gene Expression in Rust (Uromyces appendiculatus) Inoculated Common Bean (Phaseolus vulgaris L.). PMID:26167691
ErbB-3 activation by NRG-1β sustains growth and promotes vemurafenib resistance in BRAF-V600E colon cancer stem cells (CSCs). PMID:26160848
High-throughput RNA sequencing reveals structural differences of orthologous brain-expressed genes between western lowland gorillas and humans. PMID:26132897
Quantitative Proteomics Reveals the Roles of Peroxisome-associated Proteins in Antiviral Innate Immune Responses. PMID:26124285
Conditional entropy in variation-adjusted windows detects selection signatures associated with expression quantitative trait loci (eQTLs). PMID:26111110
Biomarkers for Refractory Lupus Nephritis: A Microarray Study of Kidney Tissue. PMID:26110394
ZFIN, The zebrafish model organism database: Updates and new directions. PMID:26097180
Isolation of Novel CreERT2-Driver Lines in Zebrafish Using an Unbiased Gene Trap Approach. PMID:26083735
Novel Serum Biomarkers to Differentiate Cholangiocarcinoma from Benign Biliary Tract Diseases Using a Proteomic Approach. PMID:26060332
Altered exosomal protein expression in the serum of NF-κB knockout mice following skeletal muscle ischemia-reperfusion injury. PMID:26059504
Biased random walk model for the prioritization of drug resistance associated proteins. PMID:26039373
Systematic Genome-wide Screening and Prediction of microRNAs in EBOV During the 2014 Ebolavirus Outbreak. PMID:26011078
KLF4-dependent phenotypic modulation of smooth muscle cells has a key role in atherosclerotic plaque pathogenesis. PMID:25985364
Genomic landscape of rat strain and substrain variation. PMID:25943489
Argonaute 2 Binds Directly to tRNA Genes and Promotes Gene Repression in cis. PMID:25918241
RNA sequencing reveals distinct mechanisms underlying BET inhibitor JQ1-mediated modulation of the LPS-induced activation of BV-2 microglial cells. PMID:25890327
Inorganic Arsenic-induced cellular transformation is coupled with genome wide changes in chromatin structure, transcriptome and splicing patterns. PMID:25879800
MMP7 is required to mediate cell invasion and tumor formation upon Plakophilin3 loss. PMID:25875355
Age-associated DNA methylation changes in immune genes, histone modifiers and chromatin remodeling factors within 5 years after birth in human blood leukocytes. PMID:25874017
Effects of oral exposure to bisphenol A on gene expression and global genomic DNA methylation in the prostate, female mammary gland, and uterus of NCTR Sprague-Dawley rats. PMID:25862956
MPTP's pathway of toxicity indicates central role of transcription factor SP1. PMID:25851821
A Phosphoproteomic Comparison of B-RAFV600E and MKK1/2 Inhibitors in Melanoma Cells. PMID:25850435
Global analysis of protein folding thermodynamics for disease state characterization. PMID:25825992
Understanding the rules of the road: proteomic approaches to interrogate the blood brain barrier. PMID:25788875
Identification of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase as a novel autophagy regulator by high content shRNA screening. PMID:25772235
Glucose induces sensitivity to oxygen deprivation and modulates insulin/IGF-1 signaling and lipid biosynthesis in Caenorhabditis elegans. PMID:25762526
Proteasome Dysfunction Associated to Oxidative Stress and Proteotoxicity in Adipocytes Compromises Insulin Sensitivity in Human Obesity. PMID:25714483
Identification of mammalian proteins that collaborate with type III secretion system function: involvement of a chemokine receptor in supporting translocon activity. PMID:25691588
KCNN Genes that Encode Small-Conductance Ca2+-Activated K+ Channels Influence Alcohol and Drug Addiction. PMID:25662840
Comparison of human cell signaling pathway databases--evolution, drawbacks and challenges. PMID:25632107
Differential regulation of cytotoxicity pathway discriminating between HIV, HCV mono- and co-infection identified by transcriptome profiling of PBMCs. PMID:25623235
Deeper insight into chronic kidney disease-related atherosclerosis: comparative proteomic studies of blood plasma using 2DE and mass spectrometry. PMID:25622820
Whole transcriptome analysis reveals an 8-oxoguanine DNA glycosylase-1-driven DNA repair-dependent gene expression linked to essential biological processes. PMID:25614460
Nuclear matrix protein Matrin3 regulates alternative splicing and forms overlapping regulatory networks with PTB. PMID:25599992
Predicting protein functions using incomplete hierarchical labels. PMID:25591917
Colony stimulating factor-1 receptor signaling networks inhibit mouse macrophage inflammatory responses by induction of microRNA-21. PMID:25573988
Identification of caveolar resident proteins in ventricular myocytes using a quantitative proteomic approach: dynamic changes in caveolar composition following adrenoceptor activation. PMID:25561500
Identification of protein network alterations upon retinal ischemia-reperfusion injury by quantitative proteomics using a Rattus norvegicus model. PMID:25549249
Proteomic analysis and functional characterization of mouse brain mitochondria during aging reveal alterations in energy metabolism. PMID:25546256
ROCK1 is a potential combinatorial drug target for BRAF mutant melanoma. PMID:25538140
Computational methods and opportunities for phosphorylation network medicine. PMID:25530950
In vivo assessment of protease dynamics in cutaneous wound healing by degradomics analysis of porcine wound exudates. PMID:25516628
HMGB1 facilitates repair of mitochondrial DNA damage and extends the lifespan of mutant ataxin-1 knock-in mice. PMID:25510912
MOROKOSHI: transcriptome database in Sorghum bicolor. PMID:25505007
Neuromolecular responses to social challenge: common mechanisms across mouse, stickleback fish, and honey bee. PMID:25453090
Early depletion of primordial germ cells in zebrafish promotes testis formation. PMID:25434820
The InterPro protein families database: the classification resource after 15 years. PMID:25428371
Lysine malonylation is elevated in type 2 diabetic mouse models and enriched in metabolic associated proteins. PMID:25418362
The E. coli sirtuin CobB shows no preference for enzymatic and nonenzymatic lysine acetylation substrate sites. PMID:25417765
The proteome of human retina. PMID:25407473
Anatomo-proteomic characterization of human basal ganglia: focus on striatum and globus pallidus. PMID:25406675
Chronic exposure to TGFβ1 regulates myeloid cell inflammatory response in an IRF7-dependent manner. PMID:25385836
Sustained β-catenin activity in dermal fibroblasts promotes fibrosis by up-regulating expression of extracellular matrix protein-coding genes. PMID:25385294
Phenotypic and proteomic characteristics of human dental pulp derived mesenchymal stem cells from a natal, an exfoliated deciduous, and an impacted third molar tooth. PMID:25379041
Quantitative phosphoproteomic analysis of IL-33-mediated signaling. PMID:25367039
Proteomic analysis of oral cavity squamous cell carcinoma specimens identifies patient outcome-associated proteins. PMID:25295583
Next-generation sequencing identifies equine cartilage and subchondral bone miRNAs and suggests their involvement in osteochondrosis physiopathology. PMID:25227120
Conserved and host-specific features of influenza virion architecture. PMID:25226414
Protein deep sequencing applied to biobank samples from patients with pancreatic cancer. PMID:25216700
A highly efficient tumor-infiltrating MDSC differentiation system for discovery of anti-neoplastic targets, which circumvents the need for tumor establishment in mice. PMID:25151659
Uncovering molecular events associated with the chemosuppressive effects of flaxseed: a microarray analysis of the laying hen model of ovarian cancer. PMID:25150550
SILAC-based proteomic profiling of the human MDA-MB-231 metastatic breast cancer cell line in response to the two antitumoral lactoferrin isoforms: the secreted lactoferrin and the intracellular delta-lactoferrin. PMID:25116916
Plasma proteomic changes during hypothermic and normothermic cardiopulmonary bypass in aortic surgeries. PMID:25050567
Next generation sequencing gives an insight into the characteristics of highly selected breeds versus non-breed horses in the course of domestication. PMID:24996778
Expression of transcribed ultraconserved regions of genome in rat cerebral cortex. PMID:24953281
Membrane protein profiling of human colon reveals distinct regional differences. PMID:24889196
Single-step enrichment by Ti4+-IMAC and label-free quantitation enables in-depth monitoring of phosphorylation dynamics with high reproducibility and temporal resolution. PMID:24850871
TET1-mediated hydroxymethylation facilitates hypoxic gene induction in neuroblastoma. PMID:24835990
Mammalian Y chromosomes retain widely expressed dosage-sensitive regulators. PMID:24759411
Structural, kinetic and proteomic characterization of acetyl phosphate-dependent bacterial protein acetylation. PMID:24756028
Analysis of global changes in gene expression induced by human polynucleotide phosphorylase (hPNPase(old-35)). PMID:24729470
X-exome sequencing in Finnish families with intellectual disability--four novel mutations and two novel syndromic phenotypes. PMID:24721225
Comparative epigenomics in distantly related teleost species identifies conserved cis-regulatory nodes active during the vertebrate phylotypic period. PMID:24709821
Comparative proteomic analysis of human lung telocytes with fibroblasts. PMID:24674459
A framework for organizing cancer-related variations from existing databases, publications and NGS data using a High-performance Integrated Virtual Environment (HIVE). PMID:24667251
Core binding factor β (CBFβ) is retained in the midbody during cytokinesis. PMID:24648201
Structural interrogation of phosphoproteome identified by mass spectrometry reveals allowed and disallowed regions of phosphoconformation. PMID:24618394
Pharmacogenomics of 17-alpha hydroxyprogesterone caproate for recurrent preterm birth prevention. PMID:24594138
Molecular recognition in complexes of TRF proteins with telomeric DNA. PMID:24586793
MicroRNA responses to focal cerebral ischemia in male and female mouse brain. PMID:24574964
Quantitative proteomics by SWATH-MS reveals altered expression of nucleic acid binding and regulatory proteins in HIV-1-infected macrophages. PMID:24564501
An unbiased proteomic screen reveals caspase cleavage is positively and negatively regulated by substrate phosphorylation. PMID:24556848
Non-synonymous variations in cancer and their effects on the human proteome: workflow for NGS data biocuration and proteome-wide analysis of TCGA data. PMID:24467687
Functional annotation of conserved hypothetical proteins from Haemophilus influenzae Rd KW20. PMID:24391926
Characterization and in vivo functional analysis of the Schizosaccharomyces pombe ICLN gene. PMID:24298023 -
PANTHER version 11: expanded annotation data from Gene Ontology and Reactome pathways, and data analysis tool enhancements
PubMed citations: 1038.
1038 articles citing: PANTHER version 11: expanded annotation data from Gene Ontology and Reactome pathways, and data analysis tool enhancements
Analyzing BMP2, FGFR, and TGF Beta Expressions in High-Grade Osteosarcoma Untreated and Treated Autografts Using Proteomic Analysis. PMID:35806417
Comparative Use of Contralateral and Sham-Operated Controls Reveals Traces of a Bilateral Genetic Response in the Rat Brain after Focal Stroke. PMID:35806305
Epigenetic Differences in Long Non-coding RNA Expression in Finnish and Russian Karelia Teenagers With Contrasting Risk of Allergy and Asthma. PMID:35769561
Loss of the cleaved-protamine 2 domain leads to incomplete histone-to-protamine exchange and infertility in mice. PMID:35763544
Discovery of a Multifunctional Octapeptide from Lingzhi with Antioxidant and Tyrosinase Inhibitory Activity. PMID:35745603
Polyphenols and IUGR Pregnancies: Effects of the Antioxidant Hydroxytyrosol on the Hippocampus Proteome in a Porcine Model. PMID:35740029
Effects of ACTH-Induced Long-Term Hypercortisolism on the Transcriptome of Canine Visceral Adipose Tissue. PMID:35737302
Doxycycline Alters the Porcine Renal Proteome and Degradome during Hypothermic Machine Perfusion. PMID:35723325
Neuropilin-1 is present on Foxp3+ T regulatory cell-derived small extracellular vesicles and mediates immunity against skin transplantation. PMID:35676234
Evaluation of TILI-2 as an Anti-Tyrosinase, Anti-Oxidative Agent and Its Role in Preventing Melanogenesis Using a Proteomics Approach. PMID:35630706
Intracellular Protein S-Nitrosylation-A Cells Response to Extracellular S100B and RAGE Receptor. PMID:35625541
Constraint-Based, Score-Based and Hybrid Algorithms to Construct Bayesian Gene Networks in the Bovine Transcriptome. PMID:35625151
Loss of Prm1 leads to defective chromatin protamination, impaired PRM2 processing, reduced sperm motility and subfertility in male mice. PMID:35608054
Differential gene expression profile of multinodular goiter. PMID:35594253
Genome-wide Characterization of the JmjC Domain-Containing Histone Demethylase Gene Family Reveals GhJMJ24 and GhJMJ49 Involving in Somatic Embryogenesis Process in Cotton. PMID:35573733
Comprehensive Analysis of Long Noncoding RNA Modified by m6A Methylation in Oxidative and Glycolytic Skeletal Muscles. PMID:35562992
Identifying the molecular targets of Salvia miltiorrhiza (SM) in ox-LDL induced macrophage-derived foam cells based on the integration of metabolomics and network pharmacology. PMID:35542903
Global Transcriptomic Analysis of Bacteriophage-Host Interactions between a Kayvirus Therapeutic Phage and Staphylococcus aureus. PMID:35435752
Transcriptional profiling of macrophages reveals distinct parasite stage-driven signatures during early infection by Leishmania donovani. PMID:35430587
Human pluripotent stem cell-derived myogenic progenitors undergo maturation to quiescent satellite cells upon engraftment. PMID:35395188
Predicted mouse interactome and network-based interpretation of differentially expressed genes. PMID:35390003
Genetic Diversity and Genome-Wide Association Study of Morphological and Quality Traits in Peach Using Two Spanish Peach Germplasm Collections. PMID:35386674
Phosphorylation of CAD1, PLDdelta, NDT1, RPM1 Proteins Induce Resistance in Tomatoes Infected by Ralstonia solanacearum. PMID:35336608
Pediatric Brain Tumors: Signatures from the Intact Proteome. PMID:35328618
Network Meta-Analysis of Chicken Microarray Data following Avian Influenza Challenge-A Comparison of Highly and Lowly Pathogenic Strains. PMID:35327988
Novel prevention insights into depletion of oxidative stress status through regular exercise and grape seed effective substance in heart ischemia rat model. PMID:35311161
Breed dependent regulatory mechanisms of beneficial and non-beneficial fatty acid profiles in subcutaneous adipose tissue in cattle with divergent feed efficiency. PMID:35301378
Expression and regulatory network of long noncoding RNA in rats after spinal cord hemisection injury. PMID:35259853
Fine-Scale Analysis of Runs of Homozygosity Islands Affecting Fertility in Mares. PMID:35252415
Human iPSC-derived renal organoids engineered to report oxidative stress can predict drug-induced toxicity. PMID:35243244
Investigating Glioblastoma Multiforme Sub-Proteomes: A Computational Study of CUSA Fluid Proteomic Data. PMID:35216175
An Integrated Proteomics and Bioinformatics Analysis of the Anticancer Properties of RT2 Antimicrobial Peptide on Human Colon Cancer (Caco-2) Cells. PMID:35209215
Physical Interaction between Embryonic Stem Cell-Expressed Ras (ERas) and Arginase-1 in Quiescent Hepatic Stellate Cells. PMID:35159317
Three-dimensional spatial transcriptomics uncovers cell type localizations in the human rheumatoid arthritis synovium. PMID:35149753
Developmental alterations in DNA methylation during gametogenesis from primordial germ cells to sperm. PMID:35146397
Susceptibility to disease (tropical theileriosis) is associated with differential expression of host genes that possess motifs recognised by a pathogen DNA binding protein. PMID:35061738
Impact of circ-0000221 in the Pathogenesis of Hepatocellular via Modulation of miR-661-PTPN11 mRNA Axis. PMID:35057034
2',3'-cAMP treatment mimics the stress molecular response in Arabidopsis thaliana. PMID:35043968
Transcriptome analysis reveals upregulation of immune response pathways at the invasive tumour front of metastatic seminoma germ cell tumours. PMID:35022523
Hyperphosphorylation of HDAC2 promotes drug resistance in a novel dual drug resistant mouse melanoma cell line model: an in vitro study. PMID:35018231
Potential Molecular Mechanisms and Remdesivir Treatment for Acute Respiratory Syndrome Corona Virus 2 Infection/COVID 19 Through RNA Sequencing and Bioinformatics Analysis. PMID:34992355
Biotic Stress-Induced Priming and De-Priming of Transcriptional Memory in Arabidopsis and Apple. PMID:34991272
Integration of high-resolution promoter profiling assays reveals novel, cell type-specific transcription start sites across 115 human cell and tissue types. PMID:34949670
Genome-Wide RNA-Sequencing Reveals Massive Circular RNA Expression Changes of the Neurotransmission Genes in the Rat Brain after Ischemia-Reperfusion. PMID:34946819
Gene cascade analysis in human granulosa tumor cells (KGN) following exposure to high levels of free fatty acids and insulin. PMID:34930403
Novel Insights on Obligate Symbiont Lifestyle and Adaptation to Chemosynthetic Environment as Revealed by the Giant Tubeworm Genome. PMID:34893862
Starvation to Glucose Reprograms Development of Neurovascular Unit in Embryonic Retinal Cells. PMID:34869314
SBGNview: towards data analysis, integration and visualization on all pathways. PMID:34864890
A Standardized Brain Molecular Atlas: A Resource for Systems Modeling and Simulation. PMID:34858137
Mutational Analysis and mtDNA Haplogroup Characterization in Three Serbian Cases of Mitochondrial Encephalomyopathies and Literature Review. PMID:34829316
Mitotic Errors Promote Genomic Instability and Leukemia in a Novel Mouse Model of Fanconi Anemia. PMID:34804941
Inhibition of bone morphogenetic proteins signaling suppresses metastasis melanoma: a proteomics approach. PMID:34786044
Hif-1a suppresses ROS-induced proliferation of cardiac fibroblasts following myocardial infarction. PMID:34762860
Dietary Macronutrient Imbalances Lead to Compensatory Changes in Peripheral Taste via Independent Signaling Pathways. PMID:34753739
Aging whole blood transcriptome reveals candidate genes for SARS-CoV-2-related vascular and immune alterations. PMID:34741638
Sex differences in deleterious mutational effects in Drosophila melanogaster: combining quantitative and population genetic insights. PMID:34740242
Ubiquitination is essential for recovery of cellular activities after heat shock. PMID:34739326
Toward Integrated Multi-Omics Intervention: Rice Trait Improvement and Stress Management. PMID:34721467
PANTHER: Making genome-scale phylogenetics accessible to all. PMID:34717010
FA-nf: A Functional Annotation Pipeline for Proteins from Non-Model Organisms Implemented in Nextflow. PMID:34681040
Identification of Gene Signature as Diagnostic and Prognostic Blood Biomarker for Early Hepatocellular Carcinoma Using Integrated Cross-Species Transcriptomic and Network Analyses. PMID:34659334
Network Pharmacology-Based Study of the Underlying Mechanisms of Huangqi Sijunzi Decoction for Alzheimer's Disease. PMID:34650613
Downregulation of mitochondrial biogenesis by virus infection triggers antiviral responses by cyclic GMP-AMP synthase. PMID:34648591
Clustering Spatial Transcriptomics Data. PMID:34623423
Chemical Inhibition of Apurinic-Apyrimidinic Endonuclease 1 Redox and DNA Repair Functions Affects the Inflammatory Response via Different but Overlapping Mechanisms. PMID:34616737
SMC-Derived Hyaluronan Modulates Vascular SMC Phenotype in Murine Atherosclerosis. PMID:34615369
Dissecting Genomic Determinants of Positive Selection with an Evolution-Guided Regression Model. PMID:34597406
Identification of GOLPH3 Partners in Drosophila Unveils Potential Novel Roles in Tumorigenesis and Neural Disorders. PMID:34571985
Multi-omic Analysis of Non-human Primate Heart after Partial-body Radiation with Minimal Bone Marrow Sparing. PMID:34546217
Transcriptome profiles of the skeletal muscle of mature cows during feed restriction and realimentation. PMID:34530907
Analysis of RHOA mutations and their significance in the proliferation and transcriptome of digestive tract cancer cells. PMID:34466148
Small RNA sequencing evaluation of renal microRNA biomarkers in dogs with X-linked hereditary nephropathy. PMID:34465843
Urinary Proteomics Identifying Novel Biomarkers for the Diagnosis and Phenotyping of Carotid Artery Stenosis. PMID:34447787
Insights into the Host Specificity of a New Oomycete Root Pathogen, Pythium brassicum P1: Whole Genome Sequencing and Comparative Analysis Reveals Contracted Regulation of Metabolism, Protein Families, and Distinct Pathogenicity Repertoire. PMID:34445718
Severity of Idiopathic Scoliosis Is Associated with Differential Methylation: An Epigenome-Wide Association Study of Monozygotic Twins with Idiopathic Scoliosis. PMID:34440365
Investigating the effect of positional variation on mid-lactation mammary gland transcriptomics in mice fed either a low-fat or high-fat diet. PMID:34437559
Interferon stimulated binding of ISRE is cell type specific and is predicted by homeostatic chromatin state. PMID:34409284
Metabolic impacts of cordycepin on hepatic proteomic expression in streptozotocin-induced type 1 diabetic mice. PMID:34388207
Cortical Networks of Creative Ability Trace Gene Expression Profiles of Synaptic Plasticity in the Human Brain. PMID:34381343
Male Infertility Knowledgebase: decoding the genetic and disease landscape. PMID:34363073
Epigenetic Drifts during Long-Term Intestinal Organoid Culture. PMID:34359888
Loss of Interleukin-6 Influences Transcriptional Immune Signatures and Alters Bacterial Colonization in the Skin. PMID:34295313
Identification of key molecular biomarkers involved in reactive and neurodegenerative processes present in inherited congenital hydrocephalus. PMID:34215285
Mapping the transcriptomic changes of endothelial compartment in human hippocampus across aging and mild cognitive impairment. PMID:34184731
Gene expression analysis in EBV-infected ataxia-telangiectasia cell lines by RNA-sequencing reveals protein synthesis defect and immune abnormalities. PMID:34183044
Circulating microRNAs predispose to takotsubo syndrome following high-dose adrenaline exposure. PMID:34155498
Lasp1 regulates adherens junction dynamics and fibroblast transformation in destructive arthritis. PMID:34131132
Integrating protein networks and machine learning for disease stratification in the Hereditary Spastic Paraplegias. PMID:34113825
Comparative transcriptome analysis of inner blood-retinal barrier and blood-brain barrier in rats. PMID:34108511
Urinary Cell-Free miR-99a-5p as a Potential Biomarker for Estrus Detection in Buffalo. PMID:34079831
Identification of Novel Genomic-Variant Patterns of OR56A5, OR52L1, and CTSD in Retinitis Pigmentosa Patients by Whole-Exome Sequencing. PMID:34070492
Microarray and qPCR Analysis of Mitochondrial Metabolism Activation during Prenatal and Early Postnatal Development in Rats and Humans with Emphasis on CoQ10 Biosynthesis. PMID:34066731
Glucose treatment of human pancreatic β-cells enhances translation of mRNAs involved in energetics and insulin secretion. PMID:34051232
Proteome dataset of chili pepper plant (Capsicum frutescens) infested by broad mite (Polyphagotarsonemus latus). PMID:34041315
A human liver chimeric mouse model for non-alcoholic fatty liver disease. PMID:34036256
Endosperm and Seed Transcriptomes Reveal Possible Roles for Small RNA Pathways in Wild Tomato Hybrid Seed Failure. PMID:34009298
Evolutionary, proteomic, and experimental investigations suggest the extracellular matrix of cumulus cells mediates fertilization outcomes†. PMID:34007991
A small-molecule Psora-4 acts as a caloric restriction mimetic to promote longevity in C. elegans. PMID:33988831
Extracellular vesicle-enriched miRNA profiles across pregnancy in the MADRES cohort. PMID:33979365
Identification and Functional Prediction of Long Non-Coding RNAs in Dilated Cardiomyopathy by Bioinformatics Analysis. PMID:33936172
Erosion of human X chromosome inactivation causes major remodeling of the iPSC proteome. PMID:33910018
Boosting Detection of Low-Abundance Proteins in Thermal Proteome Profiling Experiments by Addition of an Isobaric Trigger Channel to TMT Multiplexes. PMID:33908254
Cell-type-specific expression quantitative trait loci associated with Alzheimer disease in blood and brain tissue. PMID:33907181
Chromatin occupancy and target genes of the haematopoietic master transcription factor MYB. PMID:33903675
Transcriptional profile in rat muscle: down-regulation networks in acute strenuous exercise. PMID:33859869
A novel predicted ADP-ribosyltransferase-like family conserved in eukaryotic evolution. PMID:33854844
Transcriptomic Analysis of Mouse Brain After Traumatic Brain Injury Reveals That the Angiotensin Receptor Blocker Candesartan Acts Through Novel Pathways. PMID:33828448
Protein interactome of the Cancerous Inhibitor of protein phosphatase 2A (CIP2A) in Th17 cells. PMID:33817627
Set-Based Rare Variant Expression Quantitative Trait Loci in Blood and Brain from Alzheimer Disease Study Participants. PMID:33804025
The Mitochondrial Genome of a Plant Fungal Pathogen Pseudocercospora fijiensis (Mycosphaerellaceae), Comparative Analysis and Diversification Times of the Sigatoka Disease Complex Using Fossil Calibrated Phylogenies. PMID:33803147
Prioritization of candidate genes for a South African family with Parkinson's disease using in-silico tools. PMID:33770142
G-quadruplexes originating from evolutionary conserved L1 elements interfere with neuronal gene expression in Alzheimer's disease. PMID:33758195
Mammalian Flavoproteome Analysis Using Label-Free Quantitative Mass Spectrometry. PMID:33751441
Corneal proteome and differentially expressed corneal proteins in highly myopic chicks using a label-free SWATH-MS quantification approach. PMID:33750851
Integrated Proteomics and Bioinformatics to Identify Potential Prognostic Biomarkers in Hepatocellular Carcinoma. PMID:33732023
Ultra-conserved sequences in the genomes of highly diverse Anopheles mosquitoes, with implications for malaria vector control. PMID:33730159
Identification of potential and novel target genes in pituitary prolactinoma by bioinformatics analysis. PMID:33709028
Increased numbers of nucleoli in a genome-wide RNAi screen reveal proteins that link the cell cycle to RNA polymerase I transcription. PMID:33689394
Queuine Is a Nutritional Regulator of Entamoeba histolytica Response to Oxidative Stress and a Virulence Attenuator. PMID:33688012
Limited Evidence for Parallel Evolution Among Desert-Adapted Peromyscus Deer Mice. PMID:33686424
Transcriptome programming of IL-3-dependent bone marrow-derived cultured mast cells by stem cell factor (SCF). PMID:33683709
Computational Analysis Indicates That PARP1 Acts as a Histone Deacetylases Interactor Sharing Common Lysine Residues for Acetylation, Ubiquitination, and SUMOylation in Alzheimer's and Parkinson's Disease. PMID:33681613
MiR-1539 and Its Potential Role as a Novel Biomarker for Colorectal Cancer. PMID:33680906
HIR V2: a human interactome resource for the biological interpretation of differentially expressed genes via gene set linkage analysis. PMID:33677507
Adipocyte-Derived Extracellular Vesicles: State of the Art. PMID:33670146
Identification of candidate genes and pathways in retinopathy of prematurity by whole exome sequencing of preterm infants enriched in phenotypic extremes. PMID:33654115
Comprehensive in silico analysis and molecular dynamics of the superoxide dismutase 1 (SOD1) variants related to amyotrophic lateral sclerosis. PMID:33630959
Identification of host proteins differentially associated with HIV-1 RNA splice variants. PMID:33629952
Annotation of chromatin states in 66 complete mouse epigenomes during development. PMID:33619351
A Multi-OMICs Approach Sheds Light on the Higher Yield Phenotype and Enhanced Abiotic Stress Tolerance in Tobacco Lines Expressing the Carrot lycopene β-cyclase1 Gene. PMID:33613605
redPATH: Reconstructing the Pseudo Development Time of Cell Lineages in Single-cell RNA-seq Data and Applications in Cancer. PMID:33607293
Bayesian parameter estimation for automatic annotation of gene functions using observational data and phylogenetic trees. PMID:33600408
The chromatin remodeler ISWI acts during Drosophila development to regulate adult sleep. PMID:33597246
Recent Evolutionary History of Tigers Highlights Contrasting Roles of Genetic Drift and Selection. PMID:33592092
Transcriptional response of Candida albicans to Pseudomonas aeruginosa in a polymicrobial biofilm. PMID:33580263
Transcriptome Response of Liver and Muscle in Heat-Stressed Laying Hens. PMID:33578825
Bioinformatics analyses of significant genes, related pathways, and candidate diagnostic biomarkers and molecular targets in SARS-CoV-2/COVID-19. PMID:33553808
Restriction of an intron size en route to endothermy. PMID:33550394
Age-dependent VDR peak DNA methylation as a mechanism for latitude-dependent multiple sclerosis risk. PMID:33541415
Assessing technical and biological variation in SWATH-MS-based proteomic analysis of chronic lymphocytic leukaemia cells. PMID:33536534
Identifying RBM47, HCK, CD53, TYROBP, and HAVCR2 as Hub Genes in Advanced Atherosclerotic Plaques by Network-Based Analysis and Validation. PMID:33519905
The human aortic endothelium undergoes dose-dependent DNA methylation in response to transient hyperglycemia. PMID:33515594
Altered offspring neurodevelopment in an arginine vasopressin preeclampsia model. PMID:33510137
LimeMap: a comprehensive map of lipid mediator metabolic pathways. PMID:33504811
The cytoprotective protein MANF promotes neuronal survival independently from its role as a GRP78 cofactor. PMID:33460650
EBF1 drives hallmark B cell gene expression by enabling the interaction of PAX5 with the MLL H3K4 methyltransferase complex. PMID:33452395
HIF-1α promotes cellular growth in lymphatic endothelial cells exposed to chronically elevated pulmonary lymph flow. PMID:33446832
Genes Influencing Phage Host Range in Staphylococcus aureus on a Species-Wide Scale. PMID:33441407
Investigating the complex interplay between genotype and high-fat-diet feeding in the lactating mammary gland using the Tph1 and Ldlr knockout models. PMID:33427054
Identification of differentially expressed proteins and clinicopathological significance of HMGB2 in cervical cancer. PMID:33407071
RNA-Seq identifies genes whose proteins are upregulated during syncytia development in murine C2C12 myoblasts and human BeWo trophoblasts. PMID:33403800
TDP-43 aggregation induced by oxidative stress causes global mitochondrial imbalance in ALS. PMID:33398173
Glioblastoma CUSA Fluid Protein Profiling: A Comparative Investigation of the Core and Peripheral Tumor Zones. PMID:33374813
Endothelial Reprogramming by Disturbed Flow Revealed by Single-Cell RNA and Chromatin Accessibility Study. PMID:33326796
PANTHER version 16: a revised family classification, tree-based classification tool, enhancer regions and extensive API. PMID:33290554
Intercellular Mitochondria Transfer to Macrophages Regulates White Adipose Tissue Homeostasis and Is Impaired in Obesity. PMID:33278339
Identification of potential mRNA panels for severe acute respiratory syndrome coronavirus 2 (COVID-19) diagnosis and treatment using microarray dataset and bioinformatics methods. PMID:33251083
Selective packaged circular RNAs in milk extracellular vesicles during Staphylococcus aureus infection may have potential against bacterial infection. PMID:33241726
Cytoplasmic mRNA recapping has limited impact on proteome complexity. PMID:33234072
RNA sequencing analysis reveals increased expression of interferon signaling genes and dysregulation of bone metabolism affecting pathways in the whole blood of patients with osteogenesis imperfecta. PMID:33228694
Multiomic analysis identifies natural intrapatient temporal variability and changes in response to systemic corticosteroid therapy in chronic rhinosinusitis. PMID:33220024
Predicted rat interactome database and gene set linkage analysis. PMID:33216897
Exploring the Proteomic Alterations from Untreated and Cryoablation and Irradiation Treated Giant Cell Tumors of Bone Using Liquid-Chromatography Tandem Mass Spectrometry. PMID:33207819
Transcriptional regulator-induced phenotype screen reveals drug potentiators in Mycobacterium tuberculosis. PMID:33199862
Digital microfluidic isolation of single cells for -Omics. PMID:33177493
Identification of a novel missense c.386G > A variant in a boy with the POMGNT1-related muscular dystrophy-dystroglycanopathy. PMID:33175337
Full function of exon junction complex factor, Rbm8a, is critical for interneuron development. PMID:33154347
Establishment and characterisation of testicular cancer patient-derived xenograft models for preclinical evaluation of novel therapeutic strategies. PMID:33144587
DNA methylation in canine brains is related to domestication and dog-breed formation. PMID:33119634
Mechanistic Analysis of an Extracellular Signal-Regulated Kinase 2-Interacting Compound that Inhibits Mutant BRAF-Expressing Melanoma Cells by Inducing Oxidative Stress. PMID:33109619
Comprehensive characterization of amino acid positions in protein structures reveals molecular effect of missense variants. PMID:33106425
A curated list of genes that affect the plant ionome. PMID:33103043
The efficacy of chemotherapeutic drug combinations may be predicted by concordance of gene response to the single agents. PMID:33093925
Prolonged Waking and Recovery Sleep Affect the Serum MicroRNA Expression Profile in Humans. PMID:33089155
A Genome-Wide RNAi Screen for Enhancers of a Germline Tumor Phenotype Caused by Elevated GLP-1/Notch Signaling in Caenorhabditis elegans. PMID:33077477
Predicted functional interactome of Caenorhabditis elegans and a web tool for the functional interpretation of differentially expressed genes. PMID:33076954
Cross-Species RNA-Seq Study Comparing Transcriptomes of Enriched Osteocyte Populations in the Tibia and Skull. PMID:33071985
A high-throughput CRISPR interference screen for dissecting functional regulators of GPCR/cAMP signaling. PMID:33052901
Analysis of Trans-Ancestral SLE Risk Loci Identifies Unique Biologic Networks and Drug Targets in African and European Ancestries. PMID:33031749
Alveolar barrier disruption in varicella pneumonia is associated with neutrophil extracellular trap formation. PMID:33021967
Multiple Isolated Transcription Factors Act as Switches and Contribute to Species Uniqueness. PMID:33003522
Genome Profiling for Aflatoxin B1 Resistance in Saccharomyces cerevisiae Reveals a Role for the CSM2/SHU Complex in Tolerance of Aflatoxin B1-Associated DNA Damage. PMID:32994210
Identification of osteoporosis markers through bioinformatic functional analysis of serum proteome. PMID:32991410
Transcriptome analysis in osmo-primed tomato seeds with enhanced longevity by heat shock treatment. PMID:32968476
Analysis of key genes and pathways in breast ductal carcinoma in situ. PMID:32963623
Review on the Computational Genome Annotation of Sequences Obtained by Next-Generation Sequencing. PMID:32962098
SWI/SNF complexes act through CBP-1 histone acetyltransferase to regulate acute functional tolerance to alcohol. PMID:32957927
Exploring genomic variation associated with drought stress in Picea mariana populations. PMID:32953060
Expression Profiles of Long Non-coding RNA and Messenger RNA in Human Traumatic Brain Injury. PMID:32919233
Identification of the Wallenda JNKKK as an Alk suppressor reveals increased competitiveness of Alk-expressing cells. PMID:32917927
Targeting TRIM37-driven centrosome dysfunction in 17q23-amplified breast cancer. PMID:32908313
ReactomeGSA - Efficient Multi-Omics Comparative Pathway Analysis. PMID:32907876
Maternal Transmission Ratio Distortion in Two Iberian Pig Varieties. PMID:32899475
Mass spectrometry-based analysis of formalin-fixed, paraffin-embedded distal cholangiocarcinoma identifies stromal thrombospondin-2 as a potential prognostic marker. PMID:32887625
Whole Mitochondrial Genome Analysis in Serbian Cases of Leber's Hereditary Optic Neuropathy. PMID:32887465
Critical Role for Cold Shock Protein YB-1 in Cytokinesis. PMID:32882852
Mutant thermal proteome profiling for characterization of missense protein variants and their associated phenotypes within the proteome. PMID:32878984
Synchronization of human retinal pigment epithelial-1 cells in mitosis. PMID:32878943
Identification of a Plasma Microrna Signature as Biomarker of Subaneurysmal Aortic Dilation in Patients with High Cardiovascular Risk. PMID:32872191
SBML Level 3: an extensible format for the exchange and reuse of biological models. PMID:32845085
Adenosine-to-Inosine Editing of Vasoactive MicroRNAs Alters Their Targetome and Function in Ischemia. PMID:32814251
Paired Box 9 (PAX9), the RNA polymerase II transcription factor, regulates human ribosome biogenesis and craniofacial development. PMID:32813698
Molecular insights into biochar-mediated plant growth promotion and systemic resistance in tomato against Fusarium crown and root rot disease. PMID:32811849
Pregnancy-associated changes in cervical noncoding RNA. PMID:32808540
Microarray-based transcriptional profiling of a mouse model of autoimmune hepatitis. PMID:32808463
Integrated Framework of the Immune-Defense Transcriptional Signatures in the Arabidopsis Shoot Apical Meristem. PMID:32796535
Mapping the Effects of Genetic Variation on Chromatin State and Gene Expression Reveals Loci That Control Ground State Pluripotency. PMID:32795400
S-Palmitoylation as a Functional Regulator of Proteins Associated with Cisplatin Resistance in Bladder Cancer. PMID:32792852
Molecular characterization, tissue expression and polymorphisms of buffalo PPARGC1A gene. PMID:32775610
Identification of Tomato Proteins That Interact With Replication Initiator Protein (Rep) of the Geminivirus TYLCV. PMID:32760417
Modelling the developmental spliceosomal craniofacial disorder Burn-McKeown syndrome using induced pluripotent stem cells. PMID:32735620
Protamine-2 Deficiency Initiates a Reactive Oxygen Species (ROS)-Mediated Destruction Cascade during Epididymal Sperm Maturation in Mice. PMID:32727081
Interplay of RFX transcription factors 1, 2 and 3 in motile ciliogenesis. PMID:32725242
Comparison of Capillary and Schirmer Strip Tear Fluid Sampling Methods Using SWATH-MS Proteomics Approach. PMID:32714642
High-fat but not normal-fat intake of extra virgin olive oil modulates the liver proteome of mice. PMID:32712699
Self-Reporting Transposons Enable Simultaneous Readout of Gene Expression and Transcription Factor Binding in Single Cells. PMID:32710817
Molecular evolution and diversification of the GRF transcription factor family. PMID:32706846
Transcriptomic comparison of human and mouse brain microvessels. PMID:32704093
Scalable phylogenetic profiling using MinHash uncovers likely eukaryotic sexual reproduction genes. PMID:32697802
Shifts in the Holstein dairy cow milk fat globule membrane proteome that occur during the first week of lactation are affected by parity. PMID:32695335
DAZL mediates a broad translational program regulating expansion and differentiation of spermatogonial progenitors. PMID:32686646
High fat diet causes distinct aberrations in the testicular proteome. PMID:32678325
Meta-Analysis of the Alzheimer's Disease Human Brain Transcriptome and Functional Dissection in Mouse Models. PMID:32668255
Unified inference of missense variant effects and gene constraints in the human genome. PMID:32667917
Nonsense-Mediated RNA Decay Factor UPF1 Is Critical for Posttranscriptional and Translational Gene Regulation in Arabidopsis. PMID:32665305
Effects of hesperidin in orange juice on blood and pulse pressures in mildly hypertensive individuals: a randomized controlled trial (Citrus study). PMID:32661681
Mapping signalling perturbations in myocardial fibrosis via the integrative phosphoproteomic profiling of tissue from diverse sources. PMID:32661320
Sexually dimorphic impact of the iron-regulating gene, HFE, on survival in glioblastoma. PMID:32642673
Identification of Novel Molecular Markers of Human Th17 Cells. PMID:32635226
Transcriptome Analyses of Candida albicans Biofilms, Exposed to Arachidonic Acid and Fluconazole, Indicates Potential Drug Targets. PMID:32631950
Transcriptome analysis of testis reveals the effects of developmental exposure to bisphenol a or 17α-ethinylestradiol in medaka (Oryzias latipes). PMID:32622090
MicroRNA-19a-PTEN Axis Is Involved in the Developmental Decline of Axon Regenerative Capacity in Retinal Ganglion Cells. PMID:32599451
Tfam Knockdown Results in Reduction of mtDNA Copy Number, OXPHOS Deficiency and Abnormalities in Zebrafish Embryos. PMID:32596237
PRC2-mediated H3K27me3 modulates shoot iron homeostasis in Arabidopsis thaliana. PMID:32594838
Maternal dietary resistant starch does not improve piglet's gut and liver metabolism when challenged with a high fat diet. PMID:32590936
A Conserved Amino Acid in the C Terminus of Human Papillomavirus E7 Mediates Binding to PTPN14 and Repression of Epithelial Differentiation. PMID:32581101
Understanding the early cold response mechanism in IR64 indica rice variety through comparative transcriptome analysis. PMID:32580699
Novel Insights into the Protective Properties of ACTH(4-7)PGP (Semax) Peptide at the Transcriptome Level Following Cerebral Ischaemia-Reperfusion in Rats. PMID:32580520
Drosophila models of pathogenic copy-number variant genes show global and non-neuronal defects during development. PMID:32579612
Hedgehog-FGF signaling axis patterns anterior mesoderm during gastrulation. PMID:32561646
Survey for positively selected coding regions in the genome of the hematophagous tsetse fly Glossina morsitans identifies candidate genes associated with feeding habits and embryonic development. PMID:32555940
System-wide analyses of the fission yeast poly(A)+ RNA interactome reveal insights into organization and function of RNA-protein complexes. PMID:32554781
Glutaredoxin AtGRXS8 represses transcriptional and developmental responses to nitrate in Arabidopsis thaliana roots. PMID:32537558
Proteomic analysis enables distinction of early- versus advanced-stage lung adenocarcinomas. PMID:32536039
Cell-Specific Transcriptional Responses to Heat Shock in the Mouse Utricle Epithelium. PMID:32528249
Proteomic profiling of the monothiol glutaredoxin Grx3 reveals its global role in the regulation of iron dependent processes. PMID:32525871
Transcriptome Profiling of Toxoplasma gondii-Infected Human Cerebromicrovascular Endothelial Cell Response to Treatment with Monensin. PMID:32512820
Translational profiling of macrophages infected with Leishmania donovani identifies mTOR- and eIF4A-sensitive immune-related transcripts. PMID:32479529
Principal component analysis on LC‑MS/MS and 2DE‑MALDI‑TOF in glioblastoma cell lines reveals that mitochondria act as organelle sensors of the metabolic state in glioblastoma. PMID:32468038
A memory of eS25 loss drives resistance phenotypes. PMID:32463448
Comparative analysis of the skim milk and milk fat globule membrane proteomes produced by Jersey cows grazing pastures with different plant species diversity. PMID:32448582
Extending the small-molecule similarity principle to all levels of biology with the Chemical Checker. PMID:32440005
Data on miRNome changes in human cells exposed to nano- or ionic- forms of Cadmium. PMID:32426426
Functional Conservation of Divergent p63-Bound cis-Regulatory Elements. PMID:32411176
MISCAST: MIssense variant to protein StruCture Analysis web SuiTe. PMID:32402084
PaccMann: a web service for interpretable anticancer compound sensitivity prediction. PMID:32402082
Pathway Analysis of Genes Identified through Post-GWAS to Underpin Prostate Cancer Aetiology. PMID:32397189
Functional genomics analysis of human colon organoids identifies key transcription factors. PMID:32390556
The First Draft Genome of the Plasterer Bee Colletes gigas (Hymenoptera: Colletidae: Colletes). PMID:32386319
Characterization of the immune profile of oral tongue squamous cell carcinomas with advancing disease. PMID:32383556
OPTN recruitment to a Golgi-proximal compartment regulates immune signalling and cytokine secretion. PMID:32376785
Impact of differential and time-dependent autophagy activation on therapeutic efficacy in a model of Huntington disease. PMID:32374203
A structural brain network of genetic vulnerability to psychiatric illness. PMID:32372008
The metabolome as a link in the genotype-phenotype map for peroxide resistance in the fruit fly, Drosophila melanogaster. PMID:32366330
circNFIB1 inhibits lymphangiogenesis and lymphatic metastasis via the miR-486-5p/PIK3R1/VEGF-C axis in pancreatic cancer. PMID:32366257
miR-196B-5P and miR-200B-3P Are Differentially Expressed in Medulloblastomas of Adults and Children. PMID:32365560
Phosphorylation-dependent substrate selectivity of protein kinase B (AKT1). PMID:32350110
Genetic background influences tumour development in heterozygous Men1 knockout mice. PMID:32348957
Inflammatory priming enhances mesenchymal stromal cell secretome potential as a clinical product for regenerative medicine approaches through secreted factors and EV-miRNAs: the example of joint disease. PMID:32345351
The landscape of RNA polymerase II-associated chromatin interactions in prostate cancer. PMID:32343676
GATA2 and Progesterone Receptor Interaction in Endometrial Stromal Cells Undergoing Decidualization. PMID:32335672
Proteomic analysis of the S. cerevisiae response to the anticancer ruthenium complex KP1019. PMID:32329475
Acrylonitrile-Mediated Nascent RNA Sequencing for Transcriptome-Wide Profiling of Cellular RNA Dynamics. PMID:32328408
Deamidation Shunts RelA from Mediating Inflammation to Aerobic Glycolysis. PMID:32325032
Self-Incompatibility Triggers Irreversible Oxidative Modification of Proteins in Incompatible Pollen. PMID:32321844
Prostate cancer cell-intrinsic interferon signaling regulates dormancy and metastatic outgrowth in bone. PMID:32314873
Identification of HO-1 as a novel biomarker for graft acute cellular rejection and prognosis prediction after liver transplantation. PMID:32309368
The lasting after-effects of an ancient polyploidy on the genomes of teleosts. PMID:32298330
Comprehensive Analysis of AR Alterations in Circulating Tumor DNA from Patients with Advanced Prostate Cancer. PMID:32297439
Stress-mediated convergence of splicing landscapes in male and female rock doves. PMID:32293250
In Silico Prediction of the Effects of Nonsynonymous Single Nucleotide Polymorphisms in the Human Catechol-O-Methyltransferase (COMT) Gene. PMID:32236879
Tetraspanin CD9 is Regulated by miR-518f-5p and Functions in Breast Cell Migration and In Vivo Tumor Growth. PMID:32224917
Oral lichen planus interactome reveals CXCR4 and CXCL12 as candidate therapeutic targets. PMID:32214134
De novo Sequencing and Analysis of Salvia hispanica Tissue-Specific Transcriptome and Identification of Genes Involved in Terpenoid Biosynthesis. PMID:32213996
Mylk3 null C57BL/6N mice develop cardiomyopathy, whereas Nnt null C57BL/6J mice do not. PMID:32213617
ECE2 regulates neurogenesis and neuronal migration during human cortical development. PMID:32207244
Drp1 modulates mitochondrial stress responses to mitotic arrest. PMID:32203171
Coxsackievirus B3 Infection of Human Neural Progenitor Cells Results in Distinct Expression Patterns of Innate Immune Genes. PMID:32192194
Network-based identification of signature genes KLF6 and SPOCK1 associated with oral submucous fibrosis. PMID:32190310
Redox-Regulated Adaptation of Streptococcus oligofermentans to Hydrogen Peroxide Stress. PMID:32184366
Ependymoma Pediatric Brain Tumor Protein Fingerprinting by Integrated Mass Spectrometry Platforms: A Pilot Investigation. PMID:32183175
The Transcription Factor-microRNA Regulatory Network during hESC-chondrogenesis. PMID:32179818
In-depth proteome analysis of more than 12,500 proteins in buffalo mammary epithelial cell line identifies protein signatures for active proliferation and lactation. PMID:32179766
CIP2A Constrains Th17 Differentiation by Modulating STAT3 Signaling. PMID:32171124
Genome-wide DNA hypomethylation shapes nematode pattern-triggered immunity in plants. PMID:32162327
Utilization of dried and long-term stored polyacrylamide gels for the advanced proteomic profiling of mitochondrial contact sites from rat liver. PMID:32161802
Central neurogenetic signatures of the visuomotor integration system. PMID:32144139
Gene expression networks in the Drosophila Genetic Reference Panel. PMID:32144088
Context-dependent genetic architecture of Drosophila life span. PMID:32134916
Comparative and population genomics approaches reveal the basis of adaptation to deserts in a small rodent. PMID:32130752
A de novo reference transcriptome for Bolitoglossa vallecula, an Andean mountain salamander in Colombia. PMID:32123704
Antimicrobial Activity of the Quinoline Derivative HT61 against Staphylococcus aureus Biofilms. PMID:32122902
Recent advances in functional research in Giardia intestinalis. PMID:32122532
Response of metastatic mouse invasive lobular carcinoma to mTOR inhibition is partly mediated by the adaptive immune system. PMID:32117586
Novel Combined Tissue Transcriptome Analysis After Lentogenic Newcastle Disease Virus Challenge in Inbred Chicken Lines of Differential Resistance. PMID:32117434
Alveolar Macrophage Chromatin Is Modified to Orchestrate Host Response to Mycobacterium bovis Infection. PMID:32117424
Proteomic Analysis of Mucopolysaccharidosis IIIB Mouse Brain. PMID:32111039
Secreted Factors and EV-miRNAs Orchestrate the Healing Capacity of Adipose Mesenchymal Stem Cells for the Treatment of Knee Osteoarthritis. PMID:32111031
Predicted Drosophila Interactome Resource and web tool for functional interpretation of differentially expressed genes. PMID:32103267
Readthrough Errors Purge Deleterious Cryptic Sequences, Facilitating the Birth of Coding Sequences. PMID:32101291
Exploring Integrative Analysis Using the BioMedical Evidence Graph. PMID:32097025
Comparative Interactome Analysis of Emerin, MAN1 and LEM2 Reveals a Unique Role for LEM2 in Nucleotide Excision Repair. PMID:32085595
Investigating cone photoreceptor development using patient-derived NRL null retinal organoids. PMID:32081919
A lncRNA survey finds increases in neuroprotective LINC-PINT in Parkinson's disease substantia nigra. PMID:32080970
Chronic maternal interleukin-17 and autism-related cortical gene expression, neurobiology, and behavior. PMID:32074626
Developmental and molecular characterization of novel staminodes in Aquilegia. PMID:32068783
NCBP2 modulates neurodevelopmental defects of the 3q29 deletion in Drosophila and Xenopus laevis models. PMID:32053595
Quantitative SUMO proteomics identifies PIAS1 substrates involved in cell migration and motility. PMID:32047143
Computational Identification of the Proteins Associated With Quorum Sensing and Biofilm Formation in Mycobacterium tuberculosis. PMID:32038515
Proteomic profiling and identification of significant markers from high-grade osteosarcoma after cryotherapy and irradiation. PMID:32034162
Altered Hippocampal Epigenetic Regulation Underlying Reduced Cognitive Development in Response to Early Life Environmental Insults. PMID:32033187
A rare subpopulation of melanoma cells with low expression of metastasis suppressor NME1 is highly metastatic in vivo. PMID:32029850
Exosomes mediate sensory hair cell protection in the inner ear. PMID:32027617
Cancer LncRNA Census reveals evidence for deep functional conservation of long noncoding RNAs in tumorigenesis. PMID:32024996
APOE genotype regulates pathology and disease progression in synucleinopathy. PMID:32024799
Behavioral and Transcriptional Response to Selection for Olfactory Behavior in Drosophila. PMID:32024668
Global site-specific neddylation profiling reveals that NEDDylated cofilin regulates actin dynamics. PMID:32015554
Genetic Networks Underlying Natural Variation in Basal and Induced Activity Levels in Drosophila melanogaster. PMID:32014853
Aging-associated decrease in the histone acetyltransferase KAT6B is linked to altered hematopoietic stem cell differentiation. PMID:32014431
Inactivation of Zeb1 in GRHL2-deficient mouse embryos rescues mid-gestation viability and secondary palate closure. PMID:32005677
Selecting for heat tolerance. PMID:32002241
Inhibition of cytoplasmic cap methylation identifies 5' TOP mRNAs as recapping targets and reveals recapping sites downstream of native 5' ends. PMID:31996904
Clostridioides difficile-Associated Antibiotics Alter Human Mucosal Barrier Functions by Microbiome-Independent Mechanisms. PMID:31988098
NAPAbench 2: A network synthesis algorithm for generating realistic protein-protein interaction (PPI) network families. PMID:31986158
Silencing Trisomy 21 with XIST in Neural Stem Cells Promotes Neuronal Differentiation. PMID:31978324
Proteomic Analysis of Saccharomyces cerevisiae Response to Oxidative Stress Mediated by Cocoa Polyphenols Extract. PMID:31973232
A Similar Genetic Architecture Underlies the Convergent Evolution of the Selfing Syndrome in Capsella. PMID:31964802
Ovarian Transcriptomic Analyses in the Urban Human Health Pest, the Western Black Widow Spider. PMID:31940922
Inflammaging is associated with shifted macrophage ontogeny and polarization in the aging mouse ovary. PMID:31940276
Cardiac mitochondrial function depends on BUD23 mediated ribosome programming. PMID:31939735
A pipeline to create predictive functional networks: application to the tumor progression of hepatocellular carcinoma. PMID:31937236
Placental effects on the maternal brain revealed by disrupted placental gene expression in mouse hybrids. PMID:31937228
F-Actin Interactome Reveals Vimentin as a Key Regulator of Actin Organization and Cell Mechanics in Mitosis. PMID:31928973
Comprehensive transcriptome analysis of cochlear spiral ganglion neurons at multiple ages. PMID:31913118
RNA-Seq Analysis Identified XLOC_009190 as Potential Therapeutic Target for Lung Adenocarcinoma. PMID:31908488
Genetic disruption of slc4a10 alters the capacity for cellular metabolism and vectorial ion transport in the choroid plexus epithelium. PMID:31906971
Reprogramming of human fibroblasts into osteoblasts by insulin-like growth factor-binding protein 7. PMID:31904196
RNase L promotes the formation of unique ribonucleoprotein granules distinct from stress granules. PMID:31896577
CoQ10 enhances PGC1α and increases expression of mitochondrial antioxidant proteins in chronically ischemic swine myocardium. PMID:31892934
The Acute Phase Response Is a Prominent Renal Proteome Change in Sepsis in Mice. PMID:31892161
A network view of microRNA and gene interactions in different pathological stages of colon cancer. PMID:31888617
Siglec1-expressing subcapsular sinus macrophages provide soil for melanoma lymph node metastasis. PMID:31872800
Identifying Early Warning Signals for the Sudden Transition from Mild to Severe Tobacco Etch Disease by Dynamical Network Biomarkers. PMID:31861938
Proteomics Analysis of Early Developmental Stages of Zebrafish Embryos. PMID:31861170
Dynamic Growth and Shrinkage of the Salmonella-Containing Vacuole Determines the Intracellular Pathogen Niche. PMID:31851926
The dynamics of DNA methylation during epigenetic reprogramming of primordial germ cells in medaka (Oryzias latipes). PMID:31851575
Hybridization-based capture of pathogen mRNA enables paired host-pathogen transcriptional analysis. PMID:31848386
Artificially cloaked viral nanovaccine for cancer immunotherapy. PMID:31848338
Drosophila RpS12 controls translation, growth, and cell competition through Xrp1. PMID:31841522
Progerin-Induced Transcriptional Changes in Huntington's Disease Human Pluripotent Stem Cell-Derived Neurons. PMID:31834602
An Annotated Draft Genome of the Mountain Hare (Lepus timidus). PMID:31834364
Transcriptomic analyses reveal physiological changes in sweet orange roots affected by citrus blight. PMID:31829190
Comparative Network Pharmacology Analysis of Classical TCM Prescriptions for Chronic Liver Disease. PMID:31824313
Atlas of quantitative single-base-resolution N6-methyl-adenine methylomes. PMID:31822664
Integrative Activity of Mating Loci, Environmentally Responsive Genes, and Secondary Metabolism Pathways during Sexual Development of Chaetomium globosum. PMID:31822585
Differential gene expression among three sex types reveals a MALE STERILITY 1 (CpMS1) for sex differentiation in papaya. PMID:31818257
Skeletal muscle alterations in tachycardia-induced heart failure are linked to deficient natriuretic peptide signalling and are attenuated by RAS-/NEP-inhibition. PMID:31800630
Global Transcriptomic Analysis of the Canine corpus luteum (CL) During the First Half of Diestrus and Changes Induced by in vivo Inhibition of Prostaglandin Synthase 2 (PTGS2/COX2). PMID:31798528
Transcriptomic responses in mouse blood during the first week after in vivo gamma irradiation. PMID:31797975
Xylem Cell Wall Formation in Pioneer Roots and Stems of Populus trichocarpa (Torr. & Gray). PMID:31781142
Fibroblastic Reticular Cells Control Conduit Matrix Deposition during Lymph Node Expansion. PMID:31775047
PCV2 Regulates Cellular Inflammatory Responses through Dysregulating Cellular miRNA-mRNA Networks. PMID:31766254
Human induced pluripotent stem cells from two azoospermic patients with Klinefelter syndrome show similar X chromosome inactivation behavior to female pluripotent stem cells. PMID:31743397
Comparative proteome and metabolome analyses of latex-exuding and non-exuding Taraxacum koksaghyz roots provide insights into laticifer biology. PMID:31740929
Genomic adaptations to chemosymbiosis in the deep-sea seep-dwelling tubeworm Lamellibrachia luymesi. PMID:31739792
Multi-strain Tn-Seq reveals common daptomycin resistance determinants in Staphylococcus aureus. PMID:31738809
Identification of the key differentially expressed genes and pathways involved in neutrophilia. PMID:31726910
The gene structure and hypervariability of the complete Penaeus monodon Dscam gene. PMID:31719551
Gene expression analysis of the cerebellar cortex in essential tremor. PMID:31707044
Formula feeding and immature gut microcirculation promote intestinal hypoxia, leading to necrotizing enterocolitis. PMID:31704804
Unique transcriptomic landscapes identified in idiopathic spontaneous and infection related preterm births compared to normal term births. PMID:31703110
Copy number of 8q24.3 drives HSF1 expression and patient outcome in cancer: an individual patient data meta-analysis. PMID:31699156
Graphene quantum dots rescue protein dysregulation of pancreatic β-cells exposed to human islet amyloid polypeptide. PMID:31695851
Ensembl 2020. PMID:31691826
Mast Cells Are Mediators of Fibrosis and Effector Cell Recruitment in Dermal Chronic Graft-vs.-Host Disease. PMID:31681336
Co-expression of synaptic genes in the sponge Amphimedon queenslandica uncovers ancient neural submodules. PMID:31673079
NK cell defects in X-linked pigmentary reticulate disorder. PMID:31672938
Tunneling nanotube-mediated intercellular vesicle and protein transfer in the stroma-provided imatinib resistance in chronic myeloid leukemia cells. PMID:31659149
ATXN1 N-terminal region explains the binding differences of wild-type and expanded forms. PMID:31655597
Molecular Mechanism of Telomere Length Dynamics and Its Prognostic Value in Pediatric Cancers. PMID:31647544
Pathway Commons 2019 Update: integration, analysis and exploration of pathway data. PMID:31647099
Identification of microRNAs and relative target genes in Moringa oleifera leaf and callus. PMID:31641153
Inter- and intra-breed genome-wide copy number diversity in a large cohort of European equine breeds. PMID:31640551
Reconstruction of the Global Neural Crest Gene Regulatory Network In Vivo. PMID:31639368
Improving drug discovery using image-based multiparametric analysis of the epigenetic landscape. PMID:31637999
MicroRNA-411 and Its 5'-IsomiR Have Distinct Targets and Functions and Are Differentially Regulated in the Vasculature under Ischemia. PMID:31636041
A cellular and proteomic approach to assess proteins extracted from cryopreserved human amnion in the cultivation of corneal stromal keratocytes for stromal cell therapy. PMID:31632999
Transcribed B lymphocyte genes and multiple sclerosis risk genes are underrepresented in Epstein-Barr Virus hypomethylated regions. PMID:31619767
High-resolution transcriptional profiling of Anopheles gambiae spermatogenesis reveals mechanisms of sex chromosome regulation. PMID:31619757
A genome-wide assessment of the ancestral neural crest gene regulatory network. PMID:31619682
Integration of Large-Scale Genomic Data Sources With Evolutionary History Reveals Novel Genetic Loci for Congenital Heart Disease. PMID:31613678
Quantitative Proteomics Reveals a Role for SERINE/ARGININE-Rich 45 in Regulating RNA Metabolism and Modulating Transcriptional Suppression via the ASAP Complex in Arabidopsis thaliana. PMID:31608083
Blast Preconditioning Protects Retinal Ganglion Cells and Reveals Targets for Prevention of Neurodegeneration Following Blast-Mediated Traumatic Brian Injury. PMID:31598627
Fertility of Pedicellate Spikelets in Sorghum Is Controlled by a Jasmonic Acid Regulatory Module. PMID:31597271
Exploratory study on microRNA profiles from plasma-derived extracellular vesicles in Alzheimer's disease and dementia with Lewy bodies. PMID:31592314
Changes in the microsomal proteome of tomato fruit during ripening. PMID:31586085
The midbody interactome reveals unexpected roles for PP1 phosphatases in cytokinesis. PMID:31586073
Binding to medium and long chain fatty acyls is a common property of HEAT and ARM repeat modules. PMID:31578417
Neurogenomic insights into paternal care and its relation to territorial aggression. PMID:31570726
Extrapituitary prolactin promotes generation of Eomes-positive helper T cells mediating neuroinflammation. PMID:31570595
Gene expression profiling of skeletal myogenesis in human embryonic stem cells reveals a potential cascade of transcription factors regulating stages of myogenesis, including quiescent/activated satellite cell-like gene expression. PMID:31560727
Drosophila Heterochromatin Stabilization Requires the Zinc-Finger Protein Small Ovary. PMID:31558581
Association study identified biologically relevant receptor genes with synergistic functions in celiac disease. PMID:31554915
Expression Profiling of Blood microRNAs 885, 361, and 17 in the Patients with the Parkinson's disease: Integrating Interaction Data to Uncover the Possible Triggering Age-Related Mechanisms. PMID:31551498
A ribosomal protein S5 isoform is essential for oogenesis and interacts with distinct RNAs in Drosophila melanogaster. PMID:31551467
Regional epigenetic differentiation of the Z Chromosome between sexes in a female heterogametic system. PMID:31548356
Multi-Omics Analysis of Fatty Alcohol Production in Engineered Yeasts Saccharomyces cerevisiae and Yarrowia lipolytica. PMID:31543895
Similarities and differences in the biotransformation and transcriptomic responses of Caenorhabditis elegans and Haemonchus contortus to five different benzimidazole drugs. PMID:31542693
Genetic lines respond uniquely within the chicken thymic transcriptome to acute heat stress and low dose lipopolysaccharide. PMID:31541148
Physico-chemical characterization and transcriptome analysis of 5-methyltryptophan resistant lines in rice. PMID:31532784
Comprehensive proteomic profiling of plasma-derived Extracellular Vesicles from dementia with Lewy Bodies patients. PMID:31527695
Early Life Supraphysiological Levels of Oxygen Exposure Permanently Impairs Hippocampal Mitochondrial Function. PMID:31527593
Identification of proteins and miRNAs that specifically bind an mRNA in vivo. PMID:31527589
Synergistic Cytotoxicity of Renieramycin M and Doxorubicin in MCF-7 Breast Cancer Cells. PMID:31527453
Molecular Profiling of the Drosophila Antenna Reveals Conserved Genes Underlying Olfaction in Insects. PMID:31527046
Identification of bovine CpG SNPs as potential targets for epigenetic regulation via DNA methylation. PMID:31513639
Functional Genomic Analyses of Exopolysaccharide-Producing Streptococcus thermophilus ASCC 1275 in Response to Milk Fermentation Conditions. PMID:31507577
IFN-gamma-induced PD-L1 expression in melanoma depends on p53 expression. PMID:31506076
RNase L Reprograms Translation by Widespread mRNA Turnover Escaped by Antiviral mRNAs. PMID:31494035
Auxin-sensitive Aux/IAA proteins mediate drought tolerance in Arabidopsis by regulating glucosinolate levels. PMID:31492889
Production of zosteric acid and other sulfated phenolic biochemicals in microbial cell factories. PMID:31492833
Gonadal mosaicism of large terminal de novo duplication and deletion in siblings with variable intellectual disability phenotypes. PMID:31475484
Dynamical Electrical Complexity Is Reduced during Neuronal Differentiation in Autism Spectrum Disorder. PMID:31474529
Identification of modules and functional analysis in CRC subtypes by integrated bioinformatics analysis. PMID:31469863
Metabolic switches from quiescence to growth in synchronized Saccharomyces cerevisiae. PMID:31468142
Cystatin B Involvement in Synapse Physiology of Rodent Brains and Human Cerebral Organoids. PMID:31467503
An equivalence approach to the integrative analysis of feature lists. PMID:31455218
Metabolism-induced oxidative stress and DNA damage selectively trigger genome instability in polyploid fungal cells. PMID:31448850
Skeletal Muscle-Released Extracellular Vesicles: State of the Art. PMID:31447684
Regulation of Co-transcriptional Pre-mRNA Splicing by m6A through the Low-Complexity Protein hnRNPG. PMID:31445886
Randomized trial of weight loss in primary breast cancer: Impact on body composition, circulating biomarkers and tumor characteristics. PMID:31442303
Comparative Transcriptome Analysis of Pinus densiflora Following Inoculation with Pathogenic (Bursaphelenchus xylophilus) or Non-pathogenic Nematodes (B. thailandae). PMID:31434977
MAP‑1B, PACS‑2 and AHCYL1 are regulated by miR‑34A/B/C and miR‑449 in neuroplasticity following traumatic spinal cord injury in rats: Preliminary explorative results from microarray data. PMID:31432119
VOLARE: visual analysis of disease-associated microbiome-immune system interplay. PMID:31429723
Differential Expression Profiles of the Transcriptome and miRNA Interactome in Synovial Fibroblasts of Rheumatoid Arthritis Revealed by Next Generation Sequencing. PMID:31426562
Intrinsically disordered proteins and structured proteins with intrinsically disordered regions have different functional roles in the cell. PMID:31425549
A novel CpG island methylation panel predicts survival in lung adenocarcinomas. PMID:31423161
Nucleo-cytoplasmic Partitioning of ARF Proteins Controls Auxin Responses in Arabidopsis thaliana. PMID:31421981
Gene Flow in the Müllerian Mimicry Ring of a Poisonous Papuan Songbird Clade (Pitohui; Aves). PMID:31418795
WRKY1 Mediates Transcriptional Regulation of Light and Nitrogen Signaling Pathways. PMID:31409699
HuR counteracts miR-330 to promote STAT3 translation during inflammation-induced muscle wasting. PMID:31405989
Transcriptome Analysis Reveals Distinct Responses to Physiologic versus Toxic Manganese Exposure in Human Neuroblastoma Cells. PMID:31396262
Methyl-CpG-binding domain 9 (MBD9) is required for H2A.Z incorporation into chromatin at a subset of H2A.Z-enriched regions in the Arabidopsis genome. PMID:31381567
Genome Analysis Reveals Genetic Admixture and Signature of Selection for Productivity and Environmental Traits in Iraqi Cattle. PMID:31379916
Development of a Chimeric Model to Study and Manipulate Human Microglia In Vivo. PMID:31375314
Transcriptional profiling aligned with in situ expression image analysis reveals mosaically expressed molecular markers for GABA neuron sub-groups in the ventral tegmental area. PMID:31374129
Identification of potential sialic acid binding proteins on cell membranes by proximity chemical labeling. PMID:31360427
Lack of long-term acclimation in Antarctic encrusting species suggests vulnerability to warming. PMID:31358752
Comparative characterization of human induced pluripotent stem cells (hiPSC) derived from patients with schizophrenia and autism. PMID:31358727
Equine arteritis virus long-term persistence is orchestrated by CD8+ T lymphocyte transcription factors, inhibitory receptors, and the CXCL16/CXCR6 axis. PMID:31356622
Canine osteosarcoma genome sequencing identifies recurrent mutations in DMD and the histone methyltransferase gene SETD2. PMID:31341965
The molecular genetic make-up of male breast cancer. PMID:31340200
MTP18 is a Novel Regulator of Mitochondrial Fission in CNS Neuron Development, Axonal Growth, and Injury Responses. PMID:31337818
A meta-analysis of multiple matched aCGH/expression cancer datasets reveals regulatory relationships and pathway enrichment of potential oncogenes. PMID:31335867
Transcriptome Analysis Did Not Show Endogenous Stem Cell Characteristics in Murine Lgr5+ Retinal Cells. PMID:31331079
Uncovering the molecular signature underlying the light intensity-dependent root development in Arabidopsis thaliana. PMID:31325959
Identification of important invasion and proliferation related genes in adrenocortical carcinoma. PMID:31321566
Differential gene expression and AKT targeting in triple negative breast cancer. PMID:31320990
Modulation of posterior intestinal mucosal proteome in rainbow trout (Oncorhynchus mykiss) after Yersinia ruckeri infection. PMID:31315687
An in vitro attempt at precision toxicology reveals the involvement of DNA methylation alteration in ochratoxin A-induced G0/G1 phase arrest. PMID:31314649
Stress-induced Changes in the S-palmitoylation and S-nitrosylation of Synaptic Proteins. PMID:31311849
Exploring the Molecular Mechanism of the Drug-Treated Breast Cancer Based on Gene Expression Microarray. PMID:31311202
Gene expression profiles of CMS2-epithelial/canonical colorectal cancers are largely driven by DNA copy number gains. PMID:31308487
Association of imputed prostate cancer transcriptome with disease risk reveals novel mechanisms. PMID:31308362
Disease modeling of core pre-mRNA splicing factor haploinsufficiency. PMID:31304552
A role for the Saccharomyces cerevisiae ABCF protein New1 in translation termination/recycling. PMID:31299085
ChIP-exo analysis highlights Fkh1 and Fkh2 transcription factors as hubs that integrate multi-scale networks in budding yeast. PMID:31299083
Proteomic Identification and Time-Course Monitoring of Secreted Proteins During Expansion of Human Mesenchymal Stem/Stromal in Stirred-Tank Bioreactor. PMID:31297369
Three-Dimensional Genomic Structure and Cohesin Occupancy Correlate with Transcriptional Activity during Spermatogenesis. PMID:31291573
Epimutations in Developmental Genes Underlie the Onset of Domestication in Farmed European Sea Bass. PMID:31289822
Canine Bone Marrow-derived Mesenchymal Stem Cells: Genomics, Proteomics and Functional Analyses of Paracrine Factors. PMID:31285283
VIPdb, a genetic Variant Impact Predictor Database. PMID:31283070
Identification of key candidate genes for pancreatic cancer by bioinformatics analysis. PMID:31281439
Restoration of histone acetylation ameliorates disease and metabolic abnormalities in a FUS mouse model. PMID:31277703
Surface PEGylation suppresses pulmonary effects of CuO in allergen-induced lung inflammation. PMID:31277695
Comparative genome analysis of Phyllosticta citricarpa and Phyllosticta capitalensis, two fungi species that share the same host. PMID:31277573
Deep evolutionary origin of limb and fin regeneration. PMID:31270239
Glial α-synuclein promotes neurodegeneration characterized by a distinct transcriptional program in vivo. PMID:31267577
Motor dysfunction and neurodegeneration in a C9orf72 mouse line expressing poly-PR. PMID:31266945
SRAssembler: Selective Recursive local Assembly of homologous genomic regions. PMID:31266441
Effects of ATP-competitive and function-selective ERK inhibitors on airway smooth muscle cell proliferation. PMID:31266368
Meta-Analysis of Microarray Expression Studies on Metformin in Cancer Cell Lines. PMID:31261735
Multimapping confounds ribosome profiling analysis: A case-study of the Hsp90 molecular chaperone. PMID:31254414
Estimation of allele-specific fitness effects across human protein-coding sequences and implications for disease. PMID:31249063
FunSet: an open-source software and web server for performing and displaying Gene Ontology enrichment analysis. PMID:31248361
Chlorophyll catabolism precedes changes in chloroplast structure and proteome during leaf senescence. PMID:31245770
An integrated transcriptomics and metabolomics analysis of the Cucurbita pepo nectary implicates key modules of primary metabolism involved in nectar synthesis and secretion. PMID:31245763
Noncoding dsRNA induces retinoic acid synthesis to stimulate hair follicle regeneration via TLR3. PMID:31243280
Stochastic changes in gene expression promote chaotic dysregulation of homeostasis in clonal breast tumors. PMID:31240244
CTCF variants in 39 individuals with a variable neurodevelopmental disorder broaden the mutational and clinical spectrum. PMID:31239556
On estimating evolutionary probabilities of population variants. PMID:31238981
OMA standalone: orthology inference among public and custom genomes and transcriptomes. PMID:31235654
ARL3 is downregulated and acts as a prognostic biomarker in glioma. PMID:31234870
Azithromycin induces epidermal differentiation and multivesicular bodies in airway epithelia. PMID:31234850
Seawater salt-trapped Pseudomonas aeruginosa survives for years and gets primed for salinity tolerance. PMID:31234794
Signal Integration of IFN-I and IFN-II With TLR4 Involves Sequential Recruitment of STAT1-Complexes and NFκB to Enhance Pro-inflammatory Transcription. PMID:31231385
Mevalonate pathway activity as a determinant of radiation sensitivity in head and neck cancer. PMID:31225926
Identification and prioritization of macrolideresistance genes with hypothetical annotation inStreptococcus pneumoniae. PMID:31223208
Microhomology-mediated end joining drives complex rearrangements and overexpression of MYC and PVT1 in multiple myeloma. PMID:31221783
Unilateral L4-dorsal root ganglion stimulation evokes pain relief in chronic neuropathic postsurgical knee pain and changes of inflammatory markers: part II whole transcriptome profiling. PMID:31217010
Seasonal adaptations of the hypothalamo-neurohypophyseal system of the dromedary camel. PMID:31211771
miRNA contributions to pediatric-onset multiple sclerosis inferred from GWAS. PMID:31211169
Inclusion of grape marc in dairy cattle rations alters the bovine milk proteome. PMID:31210125
Machine learning with the TCGA-HNSC dataset: improving usability by addressing inconsistency, sparsity, and high-dimensionality. PMID:31208324
Limits to a classic paradigm: most transcription factors in E. coli regulate genes involved in multiple biological processes. PMID:31194874
Sex differences in sympathetic gene expression and cardiac neurochemistry in Wistar Kyoto rats. PMID:31194790
Investigating the Protein Signature of Adamantinomatous Craniopharyngioma Pediatric Brain Tumor Tissue: Towards the Comprehension of Its Aggressive Behavior. PMID:31191748
Cell Cycle-Dependent Regulation and Function of ARGONAUTE1 in Plants. PMID:31189739
Specialized eRpL22 paralogue-specific ribosomes regulate specific mRNA translation in spermatogenesis in Drosophila melanogaster. PMID:31188709
Molecular Signature of Asthma-Enhanced Sensitivity to CuO Nanoparticle Aerosols from 3D Cell Model. PMID:31188557
Multifaceted Stoichiometry Control of Bacterial Operons Revealed by Deep Proteome Quantification. PMID:31178895
Evidence that DNA repair genes, a family of tumor suppressor genes, are associated with evolution rate and size of genomes. PMID:31174607
Culturing C2C12 myotubes on micromolded gelatin hydrogels accelerates myotube maturation. PMID:31174599
Endometriosis Knowledgebase: a gene-based resource on endometriosis. PMID:31169291
ResMarkerDB: a database of biomarkers of response to antibody therapy in breast and colorectal cancer. PMID:31169290
Identification of key modules and hub genes for small-cell lung carcinoma and large-cell neuroendocrine lung carcinoma by weighted gene co-expression network analysis of clinical tissue-proteomes. PMID:31166966
Monozygotic twins and triplets discordant for amyotrophic lateral sclerosis display differential methylation and gene expression. PMID:31164693
IL-27 promotes the expansion of self-renewing CD8+ T cells in persistent viral infection. PMID:31164392
Extensive genome analysis of Coxiella burnetii reveals limited evolution within genomic groups. PMID:31164106
Differential analysis of combinatorial protein complexes with CompleXChange. PMID:31159772
PRC2-Mediated H3K27me3 Contributes to Transcriptional Regulation of FIT-Dependent Iron Deficiency Response. PMID:31156682
Genome-Wide Scan Identifies Selection Signatures in Chinese Wagyu Cattle Using a High-Density SNP Array. PMID:31151238
LnCompare: gene set feature analysis for human long non-coding RNAs. PMID:31147707
Contrasting DNA methylation responses of inbred fish lines to different rearing environments. PMID:31144573
mRNA profiling reveals significant transcriptional differences between a multipotent progenitor and its differentiated sister. PMID:31138122
Lens differentiation is characterized by stage-specific changes in chromatin accessibility correlating with differentiation state-specific gene expression. PMID:31136738
Human pancreatic cancer cell exosomes, but not human normal cell exosomes, act as an initiator in cell transformation. PMID:31134894
AXL targeting reduces fibrosis development in experimental unilateral ureteral obstruction. PMID:31134766
Proteomics Profiling of Host Cell Response via Protein Expression and Phosphorylation upon Dengue Virus Infection. PMID:31134586
Whole-genome deep-learning analysis identifies contribution of noncoding mutations to autism risk. PMID:31133750
Exploratory Gene Ontology Analysis with Interactive Visualization. PMID:31127124
Mosaic origin of the eukaryotic kinetochore. PMID:31127038
Anopheles aquasalis transcriptome reveals autophagic responses to Plasmodium vivax midgut invasion. PMID:31126324
Loss of TLE3 promotes the mitochondrial program in beige adipocytes and improves glucose metabolism. PMID:31123067
Comprehensive Multiple eQTL Detection and Its Application to GWAS Interpretation. PMID:31123039
Transcriptional consequences of impaired immune cell responses induced by cystic fibrosis plasma characterized via dual RNA sequencing. PMID:31118097
Retinal Gene Distribution and Functionality Implicated in Inherited Retinal Degenerations Can Reveal Disease-Relevant Pathways for Pharmacologic Intervention. PMID:31108889
Interspaced Repeat Sequences Confer the Regulatory Functions of AtXTH10, Important for Root Growth in Arabidopsis. PMID:31100875
Multiple genetic loci affect place learning and memory performance in Drosophila melanogaster. PMID:31095869
SIRT2 Contributes to the Resistance of Melanoma Cells to the Multikinase Inhibitor Dasatinib. PMID:31091806
A blueprint of septin expression in human tissues. PMID:31089837
Characterization of the molecular changes associated with the overexpression of a novel epithelial cadherin splice variant mRNA in a breast cancer model using proteomics and bioinformatics approaches: identification of changes in cell metabolism and an increased expression of lactate dehydrogenase B. PMID:31086659
Cell Cycle Kinase Polo Is Controlled by a Widespread 3' Untranslated Region Regulatory Sequence in Drosophila melanogaster. PMID:31085682
Cardiac Reprogramming Factors Synergistically Activate Genome-wide Cardiogenic Stage-Specific Enhancers. PMID:31080136
Human Migration and the Spread of the Nematode Parasite Wuchereria bancrofti. PMID:31077328
Exact hypothesis testing for shrinkage-based Gaussian graphical models. PMID:31077287
Bioinformatic Analysis of Gene Variants from Gastroschisis Recurrence Identifies Multiple Novel Pathogenetic Pathways: Implication for the Closure of the Ventral Body Wall. PMID:31075877
Novel transcriptional responses to heat revealed by turning up the heat at night. PMID:31062216
Non-coding and Coding Transcriptional Profiles Are Significantly Altered in Pediatric Retinoblastoma Tumors. PMID:31058073
ALK4/5-dependent TGF-β signaling contributes to the crosstalk between neurons and microglia following axonal lesion. PMID:31053759
Filamentation Regulatory Pathways Control Adhesion-Dependent Surface Responses in Yeast. PMID:31053593
A Multigene Assay Determines Risk of Recurrence in Patients with Triple-Negative Breast Cancer. PMID:31048497
Transcriptomic analysis reveals cell apoptotic signature modified by heparanase in melanoma cells. PMID:31044520
HDAC Regulates Transcription at the Outset of Axolotl Tail Regeneration. PMID:31043677
Promiscuous Targeting of Cellular Proteins by Vpr Drives Systems-Level Proteomic Remodeling in HIV-1 Infection. PMID:31042482
Associations between Maternal Tobacco Smoke Exposure and the Cord Blood [Formula: see text] DNA Methylome. PMID:31039056
A combined FSTRA-shotgun proteomics approach to identify molecular changes in zebrafish upon chemical exposure. PMID:31036921
Loss of Msh2 and a single-radiation hit induce common, genome-wide, and persistent epigenetic changes in the intestine. PMID:31029155
A genome-wide single nucleotide polymorphism and copy number variation analysis for number of piglets born alive. PMID:31029102
Divergent Fine-Scale Recombination Landscapes between a Freshwater and Marine Population of Threespine Stickleback Fish. PMID:31028697
Comparative Transcriptome Analysis of Developing Seeds and Silique Wall Reveals Dynamic Transcription Networks for Effective Oil Production in Brassica napus L. PMID:31018533
A preliminary investigation of circulating extracellular vesicles and biomarker discovery associated with treatment response in head and neck squamous cell carcinoma. PMID:31014274
The Pathway to Cancer Cachexia: MicroRNA-Regulated Networks in Muscle Wasting Based on Integrative Meta-Analysis. PMID:31013615
Liquid Chromatography Mass Spectrometry (LC-MS) analysis in determining the saliva protein of orthodontic patients during retention phase. PMID:31001398
A Mobile Auxin Signal Connects Temperature Sensing in Cotyledons with Growth Responses in Hypocotyls. PMID:31000634
Variation in pigmentation gene expression is associated with distinct aposematic color morphs in the poison frog Dendrobates auratus. PMID:30995908
Single cell transcriptomics based-MacSpectrum reveals novel macrophage activation signatures in diseases. PMID:30990466
Transcriptional Reprogramming of Arabidopsis thaliana Defence Pathways by the Entomopathogen Beauveria bassiana Correlates With Resistance Against a Fungal Pathogen but Not Against Insects. PMID:30984142
Identification of Important Invasion-Related Genes in Non-functional Pituitary Adenomas. PMID:30982163
Population Genetics of Paramecium Mitochondrial Genomes: Recombination, Mutation Spectrum, and Efficacy of Selection. PMID:30980669
Mapping the transcriptional diversity of genetically and anatomically defined cell populations in the mouse brain. PMID:30977723
Extracellular Vesicle-Based Therapeutic Targeting of β-Catenin to Modulate Anticancer Immune Responses in Hepatocellular Cancer. PMID:30976743
Comparative RNA sequencing reveals that HPV16 E6 abrogates the effect of E6*I on ROS metabolism. PMID:30976051
Bayes Factor-Based Regulatory Gene Network Analysis of Genome-Wide Association Study of Economic Traits in a Purebred Swine Population. PMID:30974885
Transcriptional and Metabolomic Analyses Indicate that Cell Wall Properties are Associated with Drought Tolerance in Brachypodium distachyon. PMID:30974727
Brain Death Enhances Activation of the Innate Immune System and Leads to Reduced Renal Metabolic Gene Expression. PMID:30964836
Sex modifies placental gene expression in response to metabolic and inflammatory stress. PMID:30955704
Physiological profile of undifferentiated bovine blastocyst-derived trophoblasts. PMID:30952696
De novo genome assembly of the white-spotted flower chafer (Protaetia brevitarsis). PMID:30949689
Risk of cognition alteration and emotional frailty via circulating transcriptome in treatment naïve head and neck squamous cell cancer patients. PMID:30949427
PTCD1 Is Required for Mitochondrial Oxidative-Phosphorylation: Possible Genetic Association with Alzheimer's Disease. PMID:30948477
Metascape provides a biologist-oriented resource for the analysis of systems-level datasets. PMID:30944313
Differential urinary proteomics analysis of myocardial infarction using iTRAQ quantification. PMID:30942401
In silico identification of key genes and signaling pathways targeted by a panel of signature microRNAs in prostate cancer. PMID:30937635
Deciphering the Pharmacological Mechanism of the Herb Radix Ophiopogonis in the Treatment of Nasopharyngeal Carcinoma by Integrating iTRAQ-Coupled 2-D LC-MS/MS Analysis and Network Investigation. PMID:30936832
Construction of prognostic microRNA signature for human invasive breast cancer by integrated analysis. PMID:30936717
The identification of differentially expressed genes between extremes of placental efficiency in maternal line gilts on day 95 of gestation. PMID:30925895
Association of Rare Coding Mutations With Alzheimer Disease and Other Dementias Among Adults of European Ancestry. PMID:30924900
Too Many False Targets for MicroRNAs: Challenges and Pitfalls in Prediction of miRNA Targets and Their Gene Ontology in Model and Non-model Organisms. PMID:30919506
Sequential conditioning-stimulation reveals distinct gene- and stimulus-specific effects of Type I and II IFN on human macrophage functions. PMID:30918279
GO functional similarity clustering depends on similarity measure, clustering method, and annotation completeness. PMID:30917779
Improved survival prognostication of node-positive malignant melanoma patients utilizing shotgun proteomics guided by histopathological characterization and genomic data. PMID:30914758
Single-cell expression profiling reveals dynamic flux of cardiac stromal, vascular and immune cells in health and injury. PMID:30912746
Snakin-1 affects reactive oxygen species and ascorbic acid levels and hormone balance in potato. PMID:30909287
Novel proteomic changes in brain mitochondria provide insights into mitochondrial dysfunction in mouse models of Huntington's disease. PMID:30902619
PTPN14 degradation by high-risk human papillomavirus E7 limits keratinocyte differentiation and contributes to HPV-mediated oncogenesis. PMID:30894485
AYbRAH: a curated ortholog database for yeasts and fungi spanning 600 million years of evolution. PMID:30893420
Human pluripotent stem cell-derived brain pericyte-like cells induce blood-brain barrier properties. PMID:30891496
Reductive Stress Selectively Disrupts Collagen Homeostasis and Modifies Growth Factor-independent Signaling Through the MAPK/Akt Pathway in Human Dermal Fibroblasts. PMID:30890563
Gene Expression Networks Across Multiple Tissues Are Associated with Rates of Molecular Evolution in Wild House Mice. PMID:30889893
Proteomic profiling of the mouse diaphragm and refined mass spectrometric analysis of the dystrophic phenotype. PMID:30888583
A Syndromic Neurodevelopmental Disorder Caused by Mutations in SMARCD1, a Core SWI/SNF Subunit Needed for Context-Dependent Neuronal Gene Regulation in Flies. PMID:30879640
Infrastructures of systems biology that facilitate functional genomic study in rice. PMID:30874968
Comprehensive analysis of the GATA transcription factor gene family in breast carcinoma using gene microarrays, online databases and integrated bioinformatics. PMID:30872657
Histone demethylase KDM6A directly senses oxygen to control chromatin and cell fate. PMID:30872525
Multispecies genome-wide analysis defines the MAP3K gene family in Gossypium hirsutum and reveals conserved family expansions. PMID:30871456
Stress response to CO2 deprivation by Arabidopsis thaliana in plant cultures. PMID:30865661
Pharmacogenomics of Multiple Sclerosis: A Systematic Review. PMID:30863357
Epigenetically dysregulated genes and pathways implicated in the pathogenesis of non-syndromic high myopia. PMID:30858441
Human Pluripotent Stem Cell-Derived Multipotent Vascular Progenitors of the Mesothelium Lineage Have Utility in Tissue Engineering and Repair. PMID:30840882
Purification of cross-linked RNA-protein complexes by phenol-toluol extraction. PMID:30824702
Characterization of a novel murine Sost ERT2 Cre model targeting osteocytes. PMID:30820362
Comparative Phosphoproteomic Profiling of Type III Adenylyl Cyclase Knockout and Control, Male, and Female Mice. PMID:30814930
Metabolomic and transcriptomic changes underlying cold and anaerobic stresses after storage of table grapes. PMID:30814549
EMT is associated with an epigenetic signature of ECM remodeling genes. PMID:30814494
Amplification of a broad transcriptional program by a common factor triggers the meiotic cell cycle in mice. PMID:30810530
Podocyte-specific expression of Cre recombinase promotes glomerular basement membrane thickening. PMID:30810063
Endogenous Gene Regulation as a Predicted Main Function of Type I-E CRISPR/Cas System in E. coli. PMID:30795631
AAV9-TAZ Gene Replacement Ameliorates Cardiac TMT Proteomic Profiles in a Mouse Model of Barth Syndrome. PMID:30788385
Genetic programming of macrophages generates an in vitro model for the human erythroid island niche. PMID:30787325
White shark genome reveals ancient elasmobranch adaptations associated with wound healing and the maintenance of genome stability. PMID:30782839
Application of Data-Independent Acquisition Approach to Study the Proteome Change from Early to Later Phases of Tomato Pathogenesis Responses. PMID:30781546
Cell-of-origin susceptibility to glioblastoma formation declines with neural lineage restriction. PMID:30778149
A galling insect activates plant reproductive programs during gall development. PMID:30755671
Genetic analysis of tomato root colonization by arbuscular mycorrhizal fungi. PMID:30753410
Multimodel inference for biomarker development: an application to schizophrenia. PMID:30745560
Computational detection and experimental validation of segmental duplications and associated copy number variations in water buffalo ( Bubalus bubalis ). PMID:30734132
AntagomiR-103 and -107 Treatment Affects Cardiac Function and Metabolism. PMID:30731323
Rheumatoid arthritis reprograms circadian output pathways. PMID:30728072
The effect of physiological stretch and the valvular endothelium on mitral valve proteomes. PMID:30722697
Characterisation and validation of Mel38; A multi-tissue microRNA signature of cutaneous melanoma. PMID:30721246
Upregulation of miR-200a and miR-204 in MPP+ -treated differentiated PC12 cells as a model of Parkinson's disease. PMID:30712312
The Systems Architecture of Molecular Memory in Poplar after Abiotic Stress. PMID:30705134
Molecular mechanisms underpinning transgenerational plasticity in the green sea urchin Psammechinus miliaris. PMID:30700813
A genome-wide scan for diversifying selection signatures in selected horse breeds. PMID:30699152
Multi-omics dataset to decipher the complexity of drug resistance in diffuse large B-cell lymphoma. PMID:30696890
Loss of CRWN Nuclear Proteins Induces Cell Death and Salicylic Acid Defense Signaling. PMID:30696746
Genome structure and evolution of Antirrhinum majus L. PMID:30692677
X-ray irradiation induces subtle changes in the genome-wide distribution of DNA hydroxymethylation with opposing trends in genic and intergenic regions. PMID:30691379
Multiple-gene targeting and mismatch tolerance can confound analysis of genome-wide pooled CRISPR screens. PMID:30683138
DNA damage and transcriptional regulation in iPSC-derived neurons from Ataxia Telangiectasia patients. PMID:30679601
s ·nr: a visual analytics framework for contextual analyses of private and public RNA-seq data. PMID:30678634
Exploration of CTCF post-translation modifications uncovers Serine-224 phosphorylation by PLK1 at pericentric regions during the G2/M transition. PMID:30676316
Meiocyte-Specific and AtSPO11-1-Dependent Small RNAs and Their Association with Meiotic Gene Expression and Recombination. PMID:30674694
Genetic Determinants of Glycated Hemoglobin in Type 1 Diabetes. PMID:30674623
Transcriptome profiling of caspase-2 deficient EμMyc and Th-MYCN mouse tumors identifies distinct putative roles for caspase-2 in neuronal differentiation and immune signaling. PMID:30670683
Thiol isomerase ERp57 targets and modulates the lectin pathway of complement activation. PMID:30670593
Functional Characterization of Ubiquitin-Like Core Autophagy Protein ATG12 in Dictyostelium discoideum. PMID:30669443
A High-quality Draft Genome Assembly of Sinella curviseta: A Soil Model Organism (Collembola). PMID:30668671
Digoxin, an Overlooked Agonist of RORγ/RORγT. PMID:30666196
Determining consistent prognostic biomarkers of overall survival and vascular invasion in hepatocellular carcinoma. PMID:30662724
Epigenomic profiling of myelofibrosis reveals widespread DNA methylation changes in enhancer elements and ZFP36L1 as a potential tumor suppressor gene that is epigenetically regulated. PMID:30655376
Rab1b and ARF5 are novel RNA-binding proteins involved in FMDV IRES-driven RNA localization. PMID:30655362
Acute Proteomic Changes in the Lung After WTLI in a Mouse Model: Identification of Potential Initiating Events for Delayed Effects of Acute Radiation Exposure. PMID:30652977
p.E95K mutation in Indian hedgehog causing brachydactyly type A1 impairs IHH/Gli1 downstream transcriptional regulation. PMID:30651074
Endocardial Notch Signaling Promotes Cardiomyocyte Proliferation in the Regenerating Zebrafish Heart through Wnt Pathway Antagonism. PMID:30650349
Robust analysis of novel mRNA-lncRNA cross talk based on ceRNA hypothesis uncovers carcinogenic mechanism and promotes diagnostic accuracy in esophageal cancer. PMID:30643460
The side population enriches for leukemia-propagating cell activity and Wnt pathway expression in zebrafish acute lymphoblastic leukemia. PMID:30630989
Proteomic Evaluation of the Acute Radiation Syndrome of the Gastrointestinal Tract in a Murine Total-body Irradiation Model. PMID:30624357
Epstein-Barr virus microRNAs regulate B cell receptor signal transduction and lytic reactivation. PMID:30615681
Comparison of DNA methylation profiles associated with spontaneous preterm birth in placenta and cord blood. PMID:30606219
RNA-binding proteins distinguish between similar sequence motifs to promote targeted deadenylation by Ccr4-Not. PMID:30601114
Nucleoredoxin-Dependent Targets and Processes in Neuronal Cells. PMID:30584462
Predicting growth rate from gene expression. PMID:30578321
Classifying mild traumatic brain injuries with functional network analysis. PMID:30577783
Clinically Relevant Post-Translational Modification Analyses-Maturing Workflows and Bioinformatics Tools. PMID:30577541
Genome sequence of walking catfish (Clarias batrachus) provides insights into terrestrial adaptation. PMID:30572844
Identification of co-located QTLs and genomic regions affecting grapevine cluster architecture. PMID:30569367
iDEP: an integrated web application for differential expression and pathway analysis of RNA-Seq data. PMID:30567491
Transcriptional Landscape of a bla KPC-2 Plasmid and Response to Imipenem Exposure in Escherichia coli TOP10. PMID:30559731
A novel role for E2F3b in regulating cocaine action in the prefrontal cortex. PMID:30552390
New Insights in Bladder Cancer Diagnosis: Urinary miRNAs and Proteins. PMID:30544619
SOG1 activator and MYB3R repressors regulate a complex DNA damage network in Arabidopsis. PMID:30541889
Comparative Analysis of Oomycete Genome Evolution Using the Oomycete Gene Order Browser (OGOB). PMID:30535146
GOnet: a tool for interactive Gene Ontology analysis. PMID:30526489
Specific MHC-I Peptides Are Induced Using PROTACs. PMID:30524438
p73 regulates ependymal planar cell polarity by modulating actin and microtubule cytoskeleton. PMID:30518789
Porcine single nucleotide polymorphisms and their functional effect: an update. PMID:30514360
Hot water extract of Agaricus blazei Murrill specifically inhibits growth and induces apoptosis in human pancreatic cancer cells. PMID:30514293
Genomic identification and functional analysis of essential genes in Caenorhabditis elegans. PMID:30514206
Data on differentially expressed proteins in retinal emmetropization process in guinea pig using integrated SWATH-based and targeted-based proteomics. PMID:30505911
Genome-wide identification of RETINOBLASTOMA RELATED 1 binding sites in Arabidopsis reveals novel DNA damage regulators. PMID:30500810
Single-Cell Imaging of Metastatic Potential of Cancer Cells. PMID:30500482
Pro-osteoporotic miR-320a impairs osteoblast function and induces oxidative stress. PMID:30485349
Transcriptome analysis of adipose tissue from pigs divergent in feed efficiency reveals alteration in gene networks related to adipose growth, lipid metabolism, extracellular matrix, and immune response. PMID:30483895
Deciphering the transcriptome of prepubertal buffalo mammary glands using RNA sequencing. PMID:30467802
Constitutive Activation of the Canonical NF-κB Pathway Leads to Bone Marrow Failure and Induction of Erythroid Signature in Hematopoietic Stem Cells. PMID:30463008
integRATE: a desirability-based data integration framework for the prioritization of candidate genes across heterogeneous omics and its application to preterm birth. PMID:30453955
Nonrandom RNAseq gene expression associated with RNAlater and flash freezing storage methods. PMID:30447171
Analysis of RNA Expression Profiles Identifies Dysregulated Vesicle Trafficking Pathways in Creutzfeldt-Jakob Disease. PMID:30446946
NMT1 inhibition modulates breast cancer progression through stress-triggered JNK pathway. PMID:30446635
Epigenetic Regulation by lncRNAs: An Overview Focused on UCA1 in Colorectal Cancer. PMID:30441811
Label-Free Quantitative Proteomics in a Methylmalonyl-CoA Mutase-Silenced Neuroblastoma Cell Line. PMID:30428564
eggNOG 5.0: a hierarchical, functionally and phylogenetically annotated orthology resource based on 5090 organisms and 2502 viruses. PMID:30418610
Gold-containing compound BDG-I inhibits the growth of A549 lung cancer cells through the deregulation of miRNA expression. PMID:30416360
Sex-specific airway hyperreactivity and sex-specific transcriptome remodeling in neonatal piglets challenged with intra-airway acid. PMID:30407862
FusionGDB: fusion gene annotation DataBase. PMID:30407583
Proteome evolution under non-substitutable resource limitation. PMID:30405128
Exploring Seipin: From Biochemistry to Bioinformatics Predictions. PMID:30402103
Exploring the genetic basis of gene transcript abundance and metabolite levels in loblolly pine (Pinus taeda L.) using association mapping and network construction. PMID:30400815
Detection of copy number variations in brown and white layers based on genotyping panels with different densities. PMID:30400769
The Lysosomal Transcription Factor TFEB Represses Myelination Downstream of the Rag-Ragulator Com