POUT-T

Collection of samples and data across the following diseases: Malignant tumour of urinary bladder (disorder), Transitional cell carcinoma. POUT-T: The translational substudy of a phase III randomised trial of peri-operative chemotherapy versus surveillance in upper tract urothelial cancer. The objectives of POUT-T are: to investigate the molecular pathogenesis of Upper Tract Urothelial Carcinoma (UTUC); to identify prognostic and predictive biomarkers of UTUC; and to identify diagnostic biomarkers of UTUC. POUT-T participants are requested to provide the following specimens pre-operatively, post operatively, 6 months following surgery, and at disease recurrence: whole blood for germline DNA analysis; whole blood for cell-free DNA analysis; first morning urine for DNA, proteome and metabolome analyses. In addition, paraffin-embedded tumour tissue from nephro-ureterectomy is requested for immunohistochemistry and DNA/RNA analyses.

Webpage:
https://www.healthdatagateway.org/dataset/4dd3f23c-44be-4126-aac5-ba655d07855c

Licence:
Name: HDR UK Innovation Gateway Access
URL: https://www.hdruk.ac.uk/infrastructure/gateway/terms-and-conditions/

Tags:

malignant tumour of urinary bladder (disorder) pout-t utuc hematologic neoplasm (disorder) transitional cell carcinoma

More to explore:

1/20

Previous Next   



Need help integrating and/or managing biomedical data?