The Proteome database LEGER (http://leger2.gbf.de/cgi-bin/expLeger.pl) was developed to support functional genome analyses by combining information obtained by applying bioinformatics methods and from public databases to improve the original annotations. LEGER offers three unique key features: (i) it is the first comprehensive information system focusing on the functional assignment of genes and proteins. (ii) Integrated visualization tools (KEGG pathway and Genome Viewer) alleviate the functional exploration of complex data and (iii) LEGER presents results of systematic post-genome studies, thus facilitating analyses combining computational and experimental results. LEGER provides an unpublished membrane proteome analysis of L. innocua and in total visualizes experimentally validated information about the subcellular localizations of 789 different listerial proteins.



genomics prokaryotic genome

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