FunTree: A Resource For Exploring The Functional Evolution Of Structurally Defined Enzyme Superfamilies
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FunTree: A Resource For Exploring The Functional Evolution Of Structurally Defined Enzyme Superfamilies
metasource: Fairsharing.org
version: FAIRsharing.org: FunTree; FunTree: A Resource For Exploring The Functional Evolution Of Structurally Defined Enzyme Superfamilies; DOI: https://doi.org/10.25504/FAIRsharing.556qpw; Last edited: April 16, 2021, 3:54 p.m.; Last accessed: Jan 03 2022 7:06 p.m.
FunTree
metasource: Fairsharing.org
version: FAIRsharing.org: FunTree; FunTree: A Resource For Exploring The Functional Evolution Of Structurally Defined Enzyme Superfamilies; DOI: https://doi.org/10.25504/FAIRsharing.556qpw; Last edited: April 16, 2021, 3:54 p.m.; Last accessed: Jan 03 2022 7:06 p.m.
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657
metasource: bio.tools
version: extracted_at: 2022-11-04T11:34:37.827407
funtree
metasource: bio.tools
version: extracted_at: 2022-11-04T11:34:37.827407
Names
More detailed information about this field from each metasource.
FunTree: A Resource For Exploring The Functional Evolution Of Structurally Defined Enzyme Superfamilies
metasource: Fairsharing.orgversion: FAIRsharing.org: FunTree; FunTree: A Resource For Exploring The Functional Evolution Of Structurally Defined Enzyme Superfamilies; DOI: https://doi.org/10.25504/FAIRsharing.556qpw; Last edited: April 16, 2021, 3:54 p.m.; Last accessed: Jan 03 2022 7:06 p.m.
FunTree
metasource: Fairsharing.orgversion: FAIRsharing.org: FunTree; FunTree: A Resource For Exploring The Functional Evolution Of Structurally Defined Enzyme Superfamilies; DOI: https://doi.org/10.25504/FAIRsharing.556qpw; Last edited: April 16, 2021, 3:54 p.m.; Last accessed: Jan 03 2022 7:06 p.m.
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657
metasource: bio.tools
version: extracted_at: 2022-11-04T11:34:37.827407
funtree
metasource: bio.toolsversion: extracted_at: 2022-11-04T11:34:37.827407
Names
More detailed information about this field from each metasource.
FunTree: A Resource For Exploring The Functional Evolution Of Structurally Defined Enzyme Superfamilies
metasource: Fairsharing.orgversion: FAIRsharing.org: FunTree; FunTree: A Resource For Exploring The Functional Evolution Of Structurally Defined Enzyme Superfamilies; DOI: https://doi.org/10.25504/FAIRsharing.556qpw; Last edited: April 16, 2021, 3:54 p.m.; Last accessed: Jan 03 2022 7:06 p.m.
FunTree
metasource: Fairsharing.orgversion: FAIRsharing.org: FunTree; FunTree: A Resource For Exploring The Functional Evolution Of Structurally Defined Enzyme Superfamilies; DOI: https://doi.org/10.25504/FAIRsharing.556qpw; Last edited: April 16, 2021, 3:54 p.m.; Last accessed: Jan 03 2022 7:06 p.m.
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657
metasource: bio.tools
version: extracted_at: 2022-11-04T11:34:37.827407
funtree
metasource: bio.toolsversion: extracted_at: 2022-11-04T11:34:37.827407
A resource for exploring the evolution of protein function through relationships in sequence, structure, phylogeny and function.
Description
More detailed information about this field from each metasource.
A resource for exploring the evolution of protein function through relationships in sequence, structure, phylogeny and function.
metasource: Fairsharing.orgversion: FAIRsharing.org: FunTree; FunTree: A Resource For Exploring The Functional Evolution Of Structurally Defined Enzyme Superfamilies; DOI: https://doi.org/10.25504/FAIRsharing.556qpw; Last edited: April 16, 2021, 3:54 p.m.; Last accessed: Jan 03 2022 7:06 p.m.
Evolution of novel enzyme functions in enzyme superfamilies
metasource: Nucleic Acid Research database catalogueversion: extracted_at: 2022-11-04T11:16:25.468657
Provides a range of data resources to detect the evolution of enzyme function within distant structurally related clusters within domain super families as determined by CATH.
metasource: bio.toolsversion: extracted_at: 2022-11-04T11:34:37.827407
Webpage:
http://www.funtree.info/FunTree/Webpage
More detailed information about this field from each metasource.
http://www.funtree.info/FunTree/
metasource: Fairsharing.orgversion: FAIRsharing.org: FunTree; FunTree: A Resource For Exploring The Functional Evolution Of Structurally Defined Enzyme Superfamilies; DOI: https://doi.org/10.25504/FAIRsharing.556qpw; Last edited: April 16, 2021, 3:54 p.m.; Last accessed: Jan 03 2022 7:06 p.m.
http://www.ebi.ac.uk/thornton-srv/databases/FunTree/
metasource: Nucleic Acid Research database catalogueversion: extracted_at: 2022-11-04T11:16:25.468657
metasource: bio.tools
version: extracted_at: 2022-11-04T11:34:37.827407
Publications:
Publications
More detailed information about this field from each metasource.
FunTree: a resource for exploring the functional evolution of structurally defined enzyme superfamilies
PMID: 22006843
metasource: Fairsharing.org
version: FAIRsharing.org: FunTree; FunTree: A Resource For Exploring The Functional Evolution Of Structurally Defined Enzyme Superfamilies; DOI: https://doi.org/10.25504/FAIRsharing.556qpw; Last edited: April 16, 2021, 3:54 p.m.; Last accessed: Jan 03 2022 7:06 p.m.
metasource: bio.tools
version: extracted_at: 2022-11-04T11:34:37.827407
FunTree: advances in a resource for exploring and contextualising protein function evolution
PMID: 26590404
metasource: Fairsharing.org
version: FAIRsharing.org: FunTree; FunTree: A Resource For Exploring The Functional Evolution Of Structurally Defined Enzyme Superfamilies; DOI: https://doi.org/10.25504/FAIRsharing.556qpw; Last edited: April 16, 2021, 3:54 p.m.; Last accessed: Jan 03 2022 7:06 p.m.
http://dx.doi.org/10.1093/nar/GKR852
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657
Publications
More detailed information about this field from each metasource.
FunTree: a resource for exploring the functional evolution of structurally defined enzyme superfamilies
PMID: 22006843
metasource: Fairsharing.org
version: FAIRsharing.org: FunTree; FunTree: A Resource For Exploring The Functional Evolution Of Structurally Defined Enzyme Superfamilies; DOI: https://doi.org/10.25504/FAIRsharing.556qpw; Last edited: April 16, 2021, 3:54 p.m.; Last accessed: Jan 03 2022 7:06 p.m.
metasource: bio.tools
version: extracted_at: 2022-11-04T11:34:37.827407
FunTree: advances in a resource for exploring and contextualising protein function evolution
PMID: 26590404
metasource: Fairsharing.org
version: FAIRsharing.org: FunTree; FunTree: A Resource For Exploring The Functional Evolution Of Structurally Defined Enzyme Superfamilies; DOI: https://doi.org/10.25504/FAIRsharing.556qpw; Last edited: April 16, 2021, 3:54 p.m.; Last accessed: Jan 03 2022 7:06 p.m.
http://dx.doi.org/10.1093/nar/GKR852
metasource: Nucleic Acid Research database catalogueversion: extracted_at: 2022-11-04T11:16:25.468657
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FunTree: a resource for exploring the functional evolution of structurally defined enzyme superfamilies
PubMed citations: 24.
24 articles citing: FunTree: a resource for exploring the functional evolution of structurally defined enzyme superfamilies
Three-dimensional Structure Databases of Biological Macromolecules. PMID:35507259
Multiple Profile Models Extract Features from Protein Sequence Data and Resolve Functional Diversity of Very Different Protein Families. PMID:35353898
Tracing Evolution Through Protein Structures: Nature Captured in a Few Thousand Folds. PMID:34041266
Bile Ductal Transcriptome Identifies Key Pathways and Hub Genes in Clonorchis sinensis-Infected Sprague-Dawley Rats. PMID:33202503
A strategy for large-scale comparison of evolutionary- and reaction-based classifications of enzyme function. PMID:32449511
Functional Evolution of Proteins. PMID:30714210
Large-scale mapping of bioactive peptides in structural and sequence space. PMID:29351315
To what extent do structural changes in catalytic metal sites affect enzyme function? PMID:29161638
Functional Annotations of Paralogs: A Blessing and a Curse. PMID:27618105
Isofunctional Protein Subfamily Detection Using Data Integration and Spectral Clustering. PMID:27348631
FunTree: advances in a resource for exploring and contextualising protein function evolution. PMID:26590404
Large-Scale Analysis Exploring Evolution of Catalytic Machineries and Mechanisms in Enzyme Superfamilies. PMID:26585402
The history of the CATH structural classification of protein domains. PMID:26253692
The Classification and Evolution of Enzyme Function. PMID:25986631
CATH: comprehensive structural and functional annotations for genome sequences. PMID:25348408
One origin for metallo-β-lactamase activity, or two? An investigation assessing a diverse set of reconstructed ancestral sequences based on a sample of phylogenetic trees. PMID:25185655
The evolution of enzyme function in the isomerases. PMID:25000289
The natural history of biocatalytic mechanisms. PMID:24874434
ENZYMAP: exploiting protein annotation for modeling and predicting EC number changes in UniProt/Swiss-Prot. PMID:24586563
The Structure-Function Linkage Database. PMID:24271399
Protein structure based prediction of catalytic residues. PMID:23433045
New functional families (FunFams) in CATH to improve the mapping of conserved functional sites to 3D structures. PMID:23203873
Enzyme informatics. PMID:23116471
Exploring the evolution of novel enzyme functions within structurally defined protein superfamilies. PMID:22396634 -
FunTree: advances in a resource for exploring and contextualising protein function evolution
PubMed citations: 3.
3 articles citing: FunTree: advances in a resource for exploring and contextualising protein function evolution
Computationally-guided drug repurposing enables the discovery of kinase targets and inhibitors as new schistosomicidal agents. PMID:30346968
Towards region-specific propagation of protein functions. PMID:30304483
Reaction Decoder Tool (RDT): extracting features from chemical reactions. PMID:27153692 - http://dx.doi.org/10.1093/nar/GKR852
Tags:
Tags
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enzyme
metasource: Fairsharing.org
version: FAIRsharing.org: FunTree; FunTree: A Resource For Exploring The Functional Evolution Of Structurally Defined Enzyme Superfamilies; DOI: https://doi.org/10.25504/FAIRsharing.556qpw; Last edited: April 16, 2021, 3:54 p.m.; Last accessed: Jan 03 2022 7:06 p.m.
evolution
metasource: Fairsharing.org
version: FAIRsharing.org: FunTree; FunTree: A Resource For Exploring The Functional Evolution Of Structurally Defined Enzyme Superfamilies; DOI: https://doi.org/10.25504/FAIRsharing.556qpw; Last edited: April 16, 2021, 3:54 p.m.; Last accessed: Jan 03 2022 7:06 p.m.
function analysis
metasource: Fairsharing.org
version: FAIRsharing.org: FunTree; FunTree: A Resource For Exploring The Functional Evolution Of Structurally Defined Enzyme Superfamilies; DOI: https://doi.org/10.25504/FAIRsharing.556qpw; Last edited: April 16, 2021, 3:54 p.m.; Last accessed: Jan 03 2022 7:06 p.m.
protein structure
metasource: Fairsharing.org
version: FAIRsharing.org: FunTree; FunTree: A Resource For Exploring The Functional Evolution Of Structurally Defined Enzyme Superfamilies; DOI: https://doi.org/10.25504/FAIRsharing.556qpw; Last edited: April 16, 2021, 3:54 p.m.; Last accessed: Jan 03 2022 7:06 p.m.
metabolic and signaling pathways
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657
enzymes and enzyme nomenclature
metasource: Nucleic Acid Research database catalogue
version: extracted_at: 2022-11-04T11:16:25.468657
enzymes
metasource: bio.tools
version: extracted_at: 2022-11-04T11:34:37.827407
small molecules
metasource: bio.tools
version: extracted_at: 2022-11-04T11:34:37.827407
protein folds and structural domains
metasource: bio.tools
version: extracted_at: 2022-11-04T11:34:37.827407
structure analysis
metasource: bio.tools
version: extracted_at: 2022-11-04T11:34:37.827407
phylogenetics
metasource: bio.tools
version: extracted_at: 2022-11-04T11:34:37.827407
Tags
More detailed information about this field from each metasource.
enzyme
metasource: Fairsharing.orgversion: FAIRsharing.org: FunTree; FunTree: A Resource For Exploring The Functional Evolution Of Structurally Defined Enzyme Superfamilies; DOI: https://doi.org/10.25504/FAIRsharing.556qpw; Last edited: April 16, 2021, 3:54 p.m.; Last accessed: Jan 03 2022 7:06 p.m.
evolution
metasource: Fairsharing.orgversion: FAIRsharing.org: FunTree; FunTree: A Resource For Exploring The Functional Evolution Of Structurally Defined Enzyme Superfamilies; DOI: https://doi.org/10.25504/FAIRsharing.556qpw; Last edited: April 16, 2021, 3:54 p.m.; Last accessed: Jan 03 2022 7:06 p.m.
function analysis
metasource: Fairsharing.orgversion: FAIRsharing.org: FunTree; FunTree: A Resource For Exploring The Functional Evolution Of Structurally Defined Enzyme Superfamilies; DOI: https://doi.org/10.25504/FAIRsharing.556qpw; Last edited: April 16, 2021, 3:54 p.m.; Last accessed: Jan 03 2022 7:06 p.m.
protein structure
metasource: Fairsharing.orgversion: FAIRsharing.org: FunTree; FunTree: A Resource For Exploring The Functional Evolution Of Structurally Defined Enzyme Superfamilies; DOI: https://doi.org/10.25504/FAIRsharing.556qpw; Last edited: April 16, 2021, 3:54 p.m.; Last accessed: Jan 03 2022 7:06 p.m.
metabolic and signaling pathways
metasource: Nucleic Acid Research database catalogueversion: extracted_at: 2022-11-04T11:16:25.468657
enzymes and enzyme nomenclature
metasource: Nucleic Acid Research database catalogueversion: extracted_at: 2022-11-04T11:16:25.468657
enzymes
metasource: bio.toolsversion: extracted_at: 2022-11-04T11:34:37.827407
small molecules
metasource: bio.toolsversion: extracted_at: 2022-11-04T11:34:37.827407
protein folds and structural domains
metasource: bio.toolsversion: extracted_at: 2022-11-04T11:34:37.827407
structure analysis
metasource: bio.toolsversion: extracted_at: 2022-11-04T11:34:37.827407
phylogenetics
metasource: bio.toolsversion: extracted_at: 2022-11-04T11:34:37.827407
enzyme evolution function analysis protein structure metabolic and signaling pathways enzymes and enzyme nomenclature enzyme small molecule protein folds and structural domains structure analysis phylogenetics
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