Watch and Wait Trial

Collection of samples and data across the following diseases: Malignant lymphoma (disorder) Watch and Wait is a randomised phase III trial to determine whether initial treatment with rituximab in patients with advanced stage asymptomatic follicular lymphoma (grades 1, 2 and 3a) results in a significant delay in the initiation of chemotherapy or radiotherapy and the impact of each strategy on patient-related quality of life. 360 patients randomised to receive either Rituximab treatment and maintenance or to a Watch and Wait strategy. Samples collected for trial: Formalin fixed paraffin embedded tumour block or unstained slides (lymph node and bone marrow)- sent to HMDS. Blood and bone marrow sample taken at baseline and if patient in CR clinically and radiologically at 7, 13 and 25 months - sent to University College London Hospital.

Webpage:
https://www.healthdatagateway.org/dataset/30a0ee0e-d9f9-4341-b00c-2fab8f122b5f

Licence:
Name: HDR UK Innovation Gateway Access
URL: https://www.hdruk.ac.uk/infrastructure/gateway/terms-and-conditions/

Tags:

trial malignant lymphoma (disorder) watch and wait

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