RATHL Trial

Collection of samples and data across the following diseases: Malignant lymphoma (disorder) RATHL is a multicentre, randomised, phase III trial comparing treatment outcome for patients with advanced Hodgkin lymphoma, using FDG-PET imaging after 2 cycles of ABVD to determine response and subsequent management. Recruitment target: 1200 patients Patients received 2 cycles of ABVD and then had a PET-CT scan. PET negative patients were randomised to either ABVD or AVD for a further 4 cycles. PET positive patients received either BEACOPP-14, for 4-6 cycles or BEACOPP escalated, for 3-4 cycles. Samples collected for trial: Formalin fixed paraffin embedded tumour block - sent to HMDS, Leeds. Blood sample to be analysed at site. Blood sample - sent to Simpson Centre for Reproductive Health, Edinburgh.

Webpage:
https://www.healthdatagateway.org/dataset/99812cec-ea1c-4979-8e00-32df5bad000b

Licence:
Name: HDR UK Innovation Gateway Access
URL: https://www.hdruk.ac.uk/infrastructure/gateway/terms-and-conditions/

Tags:

fdg-pet hodgkin lymphoma trial abvd malignant lymphoma (disorder) rathl

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